Clinical trials: Post-operative Delirium
Delirium and Post-operative Cognitive Dysfunction (POCD)
Cognitive Outcome After Two-stage Liver-Operation
Cognitive outcome (delirium and post-operative cognitive deficiency) in patients undergoing two-time liver resection.
- Trial name
- 2-StaLi (NCT01809782)
- Where
- Germany
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Delirium
Hypertension and Controlled Hypotension in the Elderly
Comparision of Exposed Factors of Preoperative Hypertension and Intraoperative Controlled Hypotension on Postoperative Delirium in the Elderly under Radical Resection of Head, Neck and Maxillofacial Tumor
- Trial name
- NCT04433416
- Testing
- hypertension
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Zhang Lei
Delirium, Postoperative
Effect of Percutaneous Acupoint Electrical Stimulation on Delirium
This study is a multicenter, prospective, randomized controlled clinical trial that aims to observe the impact of Transcutaneous Electrical Acupoint Stimulation (TEAS) on plasma TK/MMP3 in a randomized controlled setting.
- Trial name
- NCT06360549
- Testing
- Transcutaneous Electrical Acupoint Stimulation
- Where
- 2 sites in China
- Volunteers
- 238 people
- Sponsor
- Qin Zhang
Delirium - Postoperative, Hip Fracture Surgeries
DEX-HIP Trial: Preoperative IV Dexamethasone 4 mg vs Placebo to Reduce Postoperative Delirium Burden in Adults ≥70 Undergoing Hip Fracture Surgery
This single-center, prospective, randomized, double-blind, placebo-controlled trial was conducted at the Department of Orthopaedic Surgery, JPMC, Karachi.
- Conditions
- Delirium - Postoperative, Hip Fracture Surgeries, Steroid
- Trial name
- NCT07651150
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Delirium - Postoperative, Anxiety Acute
Pediatric Recovery Delirium in Pediatric Patients Undergoing Surgery
The primary aim of this observational study is to evaluate the effect of playing a mother's voice to a child while the patient is being awakened from anesthesia on postoperative delirium.
- Trial name
- Delirium (NCT07413289)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Enes Celik
Frail Elderly Syndrome, Primary Prevention
Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams
The increase in the population over 60 years of age who could receive surgery due to changes in life expectancy and advances in surgical and anesthetic techniques.
- Conditions
- Frail Elderly Syndrome, Primary Prevention, Postoperative Delirium, Frailty
- Trial name
- NPPOD (NCT05993754)
- Testing
- Non-pharmacological intervention
- Where
- Chile
- Volunteers
- 400 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Postoperative Delirium (POD), Postoperative Sleep Disturbance
Effects of Esketamine on the Incidence of Postoperative Delirium and Postoperative Sleep Disturbance in Elderly Patients After Major Non-cardiac Surgery
Postoperative delirium (POD) is a common surgical complication.It is associated with a range of negative outcomes such as delayed postoperative recovery,prolonged hospitalization,additional medical expenditures and higher…
- Trial name
- EPISODE (NCT06900205)
- Testing
- Esketamine, 0.9 % saline
- Where
- China
- Sponsor
- RenJi Hospital
Postoperative Delirium, Elderly
The Association Between SIRI and POD in Older Patients
Postoperative delirium (POD) remains one of most common complication in elderly patients receiving surgery, which is characterized by acute and fluctuating change in the level of cognition and consciousness.
- Conditions
- Postoperative Delirium, Elderly, Surgery
- Trial name
- NCT05797194
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Changhai Hospital
Emergence Delirium, Pediatric Dental General Anesthesia
Pre-emptive Local Anesthesia and Emergence Behavior After Pediatric Dental General Anesthesia
This study will evaluate whether pre-emptive local anesthesia improves early recovery after ambulatory pediatric dental general anesthesia.
- Conditions
- Emergence Delirium, Pediatric Dental General Anesthesia, Postoperative Recovery
- Trial name
- PEDLA-QOR (NCT07604337)
- Testing
- Pre-emptive Local Anesthesia, Articaine Hydrochloride With Epinephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- seher orbay yasli
Postoperative Confusion
Automated Visual Monitoring for Improving Patient Safety (VIPSafe)
After an operation many patients are in a confused mental status at the intensive care unit. In this status they possibly fall out of their bed or pull out endotracheal tubes or central venous catheters accidentally.
- Trial name
- VIPSafe (NCT01317407)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Staedtisches Klinikum Karlsruhe
Emergence Delirium, Agitation, Emergence
Mitigation of Emergence Agitation Through Implementation of Masimo Bridge Therapy
This is a randomized, prospective, double-blinded (patient and outcome-assessor) trial. Our goal is to assess efficacy of Bridge Therapy (versus sham bridge therapy) to prevent emergence agitation following general anesthesia.
- Trial name
- NCT06387953
- Testing
- Bridge Therapy
- Sponsor
- University of Washington
Anesthesia, General
Maternal Voice on Anesthetic Emergence Period
Mother spend a large amount of time with their children. It is assumed that mother contributes to their neurological development not only with visual stimuli, but also with auditory stimuli.
- Trial name
- MatherVoice (NCT02860377)
- Testing
- recorded maternal voice, recorded stranger's voice
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Daegu Catholic University Medical Center
Frail Elderly Syndrome, Postoperative Delirium
Different Frailty Scores to Incidence of Post-operative Delirium and Cognitive Dysfunction
Patients who are frail will have higher rate for post-operative morbidities, mortality, prolonged hospital stays, loss of independence, increase in institutionalization, post-operative cognitive dysfunction (POCD) and delirium…
- Conditions
- Frail Elderly Syndrome, Postoperative Delirium, Postoperative Cognitive Dysfunction
- Trial name
- NCT04056871
- Testing
- Frailty Screening Tools
- Where
- Malaysia
- Volunteers
- 400 people
- Sponsor
- University of Malaya
Behavior Problem
Intranasal Dexmedetomidine or Esketamine for Negative Postoperative Behavioral Changes in Children
The goal of this clinical trial is to learn whether intranasal dexmedetomidine or esketamine given before anesthesia can reduce negative postoperative behavioral changes in children undergoing day surgery.
- Trial name
- PEDI-NPOBCs (NCT07570160)
- Testing
- Dexmedetomidine, Esketamine, Normal Saline
- Where
- China
- Volunteers
- 342 people
- Sponsor
- Nanjing Children's Hospital
Postoperative Delirium, Gut Microbiota
Characterisation of Gut Microbiota in Patients Undergoing Gastrointestinal Surgery With Postoperative Delirium (GIM-POD)
The study is a case-controlled observational trial. Sixty patients will be divided into 2 groups depending on whether postoperative delirium or not.
- Trial name
- GIM-POD (NCT04316910)
- Testing
- General anesthetic
- Where
- China
- Volunteers
- 30 people
- Sponsor
- China Medical University, China
Confusion, Inflammation
Confusion in the Elderly After Colon Surgery
A study will be conducted to determine if there is any cognitive benefit in elderly patients having open versus minimally invasive colon cancer surgery.
- Conditions
- Confusion, Inflammation, Acute Phase Reaction, Surgery
- Trial name
- NCT01623297
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- New York Hospital Queens
Electroencephalogram, Postoperative Delirium (POD)
Electroencephalogram Characteristics of Surgical Anesthetized Patients and Postoperative Dilirium
Objective: To construct a perioperative EEG database for elderly patients under general anesthesia and to explore the relationship between their EEG spectrum characteristics and the occurrence and severity of postoperative…
- Trial name
- NCT06394778
- Testing
- Delirium test scale：3D-CAM
- Where
- China
- Volunteers
- 375 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Postoperative Delirium, PD
Perioperative Cognitive Function - Dexmedetomidine and Cognitive Reserve
Elderly patients who undergo anesthesia and non-cardiac surgery are subject to deterioration of brain function including the development of postoperative delirium (PD) and postoperative cognitive dysfunction (POCD).
- Conditions
- Postoperative Delirium, PD, Postoperative Cognitive Dysfunction, POCD
- Trial name
- NCT00561678
- Testing
- Precedex (Dexmedetomidine)
- Where
- 10 sites in United States
- Volunteers
- 404 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anemia, Delirium
Elderly With Hip Fracture and Perioperative Hemoglobin and Perfusion Index Levels
The overall aim of the study is to investigate the time difference in the diagnosing of anemia among elderly with hip fracture, between measurements with standard blood samples and non-invasive SpHb-measuring.
- Trial name
- NCT02838706
- Testing
- Surgery for hip fracture
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Hvidovre University Hospital
Emergence Delirium, Perioperative Neurocognitive Disorder
Quantitative Neurofeedback Techniques for Treating Perioperative Cognitive Disorders in Elderly Patients
The goal of this clinical trial is to learn if quantitative measurement of brain and neurofeedback intervention techniques works to prevent perioperative neurocognitive deficits in elderly oncology patients who are to undergo…
- Trial name
- NCT06752148
- Testing
- neurofeedback intervention training game
- Volunteers
- 390 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences