Clinical trials: Post-operative Nausea and Vomiting (PONV)
Colonic Diseases, Functional
Adequacy of Anaesthesia for Colonoscopic Procedures
The aim of this randomized prospective trial is to assess the utility of Adequacy of Anaesthesia technique (Response Entropy and Surgical Pleth Index) for monitoring pain perception intraoperatively and its influence on…
- Trial name
- AoAColon (NCT03922815)
- Testing
- rescue fentanyl, rescue propofol
- Where
- Poland
- Volunteers
- 158 people
- Sponsor
- Medical University of Silesia
Postoperative Nausea and Vomiting (PONV)
Dexamethasone for Prevention of Postoperative Vomiting After Laparoscopic Gynecologic Surgery
Postoperative nausea and vomiting (PONV) are common and distressing complications following laparoscopic gynecologic surgery. This randomized controlled trial evaluated whether a single preoperative intravenous dose of…
- Trial name
- PONV-DEX-GYN (NCT07421817)
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Rawalpindi Medical College
Enhanced Recovery After Surgery, Hospital Stay, Length of Stay in Hospital From Time of Surgery Till Discharge
Resumption of Enteral Feeding After Bowel Anastomosis
Resumption of oral feeding after small intestine surgery is a matter of controversy .Some surgeons advocate early resumption while others don't.early feeding is initiated as soon as the patient recovers from effects of…
- Conditions
- Enhanced Recovery After Surgery, Hospital Stay, Length of Stay in Hospital From Time of Surgery Till Discharge, Defecation, Vomiting, Postoperative
- Trial name
- NCT06906289
- Testing
- resumption of enteral feeding within 24 hours of surgery, resumption of enteral feeding after 24-48 hours
- Where
- Pakistan
- Volunteers
- 204 people
- Sponsor
- Khyber Teaching Hospital
Postoperative Nausea and Vomiting
The Effects of Gabapentin and Ramosetron on Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
This study was designed to compare the effects of gabapentin and ramosetron on PONV in patients undergoing laparoscopic gynecologic surgery.
- Trial name
- PONV (NCT02617121)
- Testing
- Gabapentin, Ramosetron, Gabapentin and Ramosetron
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hallym University Medical Center
Nausea, Vomiting
Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries
The combination of aprepitant and lower dose dexamethasone is superior to aprepitant alone with respect to the proportion of patients with a complete response (no vomiting and no use of rescue therapy) during 24 hours after the…
- Trial name
- NCT00835965
- Testing
- Dexamethasone, Aprepitant
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Main Line Health
Laparoscopic Surgery, Pediatrics
Effect of Palonosetron, Ondansetron and Dexamethasone in the Prevention of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) is an important outcome for the patient; patients generally rate PONV as worse than postoperative pain.
- Conditions
- Laparoscopic Surgery, Pediatrics, Nausea and Vomiting, Postoperative, Antiemetics
- Trial name
- NCT05439798
- Testing
- Ondansetron+Dexamethasone, Palonosetron+Dexamethasone, Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Selcuk University
PONV, BIS
Effect of BIS-Guided Anesthesia on Postoperative Nausea and Vomiting in Pediatric Patients
This randomized controlled trial will evaluate the effect of bispectral index (BIS)-guided anesthesia on postoperative nausea and vomiting (PONV) in children aged 3-8 years undergoing elective adenoidectomy.
- Trial name
- NCT07189845
- Testing
- BIS GROUP, CONTROL GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Engin Çetin
Vitreoretinal Surgeries, Postoperative Nausea and Vomiting
Different Peribulbar Blocks With SPI-guided Anaesthesia for VRS (P&MSPIVRS)
The aim of this randomized trial is to assess the efficacy of preventive analgesia using different peribulbar blocks (PBB) under SPI-guided anaesthesia for vitreoretinal surgery (VRS), presence of PONV (postoperative nausea and…
- Conditions
- Vitreoretinal Surgeries, Postoperative Nausea and Vomiting, Postoperative Pain, Oculocardiac Reflex
- Trial name
- PBBVRS (NCT03413371)
- Testing
- paracetamol, 0,5 % bupivacaine with of 2% lidocaine, 1 % Ropivacaine
- Where
- Poland
- Volunteers
- 184 people
- Sponsor
- Medical University of Silesia
Nausea and Vomiting, Postoperative
Impact of ERAS on Postoperative Nausea and Vomiting After Sleeve
The use of bariatric surgery in the treatment of severe obesity has several benefits in terms of sustainable weight loss, improvements, or resolution of several metabolic comorbidities as well as improved life expectancy.
- Trial name
- NCT05996887
- Testing
- standard care protcol, enhanced recovery protocol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Postoperative Nausea and Vomiting
Preemptive Versus Preventive Antiemetic Treatment
Patients aged between 20 and 70 years, ASA physical status I-III, and scheduled for laparoscopic cholecystectomy under general anaesthesia will be enrolled in the study.
- Trial name
- NCT03023306
- Testing
- Antiemetics perioperatively
- Where
- Greece
- Volunteers
- 115 people
- Sponsor
- University of Athens
Postoperative Nausea and Vomiting, Postoperative Pain
Postoperative Nausea, Vomiting and Pain After Bariatric Surgery - a National Registry Study
Around 4,000-5,000 bariatric (weight-loss) operations are performed in Sweden every year. Nausea, vomiting and pain are common immediately after these operations, cause considerable suffering and increase the intensity and length…
- Conditions
- Postoperative Nausea and Vomiting, Postoperative Pain, Obesity, Morbid, Bariatric Surgery
- Trial name
- BAROSPOR (NCT07797374)
- Where
- 2 sites in Sweden
- Volunteers
- 30,000 people
- Sponsor
- Umeå University
Postoperative Nausea and Vomiting, Opioid Use
Effect of Opioid-free Anesthesia on PostOperative Nausea and Vomiting in Patients Undergoing Video-assisted Thoracoscopic Surgery
This study aimed to verify whether an Opioid-free Anesthesia (OFA) could effectively reduce the incidence of PONV after thoracoscopic-assisted surgery compared with standard general anesthesia (OA) regimens.
- Conditions
- Postoperative Nausea and Vomiting, Opioid Use, Thoracic Diseases
- Trial name
- OFA-PONV (NCT05411159)
- Testing
- Opioid-Free Anesthesia (OFA), Standard general anesthesia (OA)
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Beijing Chao Yang Hospital
Postoperative Nausea and Vomiting, Postoperative Complications
Early PONV - a Registry Based Study in Sweden.
The study is an registry study based on data from the Swedish Perioperative Registry (SPOR) during the years 2016-2022 with the aim to explore the risk for postoperative nausea and vomiting at the recovery unit (early PONV).
- Trial name
- SPOR-PONV (NCT04433676)
- Testing
- no intervention
- Where
- Sweden
- Volunteers
- 1,500,000 people
- Sponsor
- Jakob Wallden
Postoperative Nausea, Postoperative Vomiting
Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial
The goal of this prospective, unblinded, pragmatic and repeated crossover trial is to learn if clinical decision support alerts will impact postoperative nausea and vomiting (PONV) prophylaxis and reduce PONV rates in adult…
- Trial name
- ASPIRE-PONV (NCT07152249)
- Testing
- AW-D Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 19,480 people
- Sponsor
- Vanderbilt University Medical Center
Postoperative Nausea and Vomiting
Effects of taVNS Combined With Dexmedetomidine on POVN
To explore the effects and possible mechanisms of dexmedetomidine combined with taVNS on the incidence of postoperative nausea and vomiting in female patients undergoing laparoscopic surgery
- Trial name
- NCT07271147
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulator, Dexmedetomidine
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Affiliated Hospital of Nantong University
Pediatric Anesthesia, Postoperative Nausea and Vomiting (PONV)
Inflammatory Biomarkers as Predictors of PONV Following Pediatric Orchiopexy
Orchiopexy is a common surgical procedure for the treatment of cryptorchidism in the pediatric population, with a high incidence of postoperative nausea and vomiting (PONV).
- Conditions
- Pediatric Anesthesia, Postoperative Nausea and Vomiting (PONV), Inflammatory Biomarkers
- Trial name
- NCT07148063
- Testing
- Measurement of Preoperative Inflammatory Biomarkers
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Postoperative Nausea and Vomiting
Antiemetic Efficacy and Safety of Dexamethasone in Obstetric Surgical Patients
This is a randomised controlled double blinded clinical trial to determine the antiemetic efficacy and safety of either 8 mg of dexamethasone or normal saline (placebo) given 1 hour before induction of either spinal or general…
- Trial name
- NCT01028547
- Testing
- dexamethasone, normal saline
- Where
- Uganda
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Makerere University
Dexamethasone Adverse Reaction, Postoperative Pain
Role of Dexamethasone in Multimodal Analgesia for Postoperative Pain in Thoracic Surgery
The aim of the study is to evaluate the analgesic properties of dexamethasone and to quantify the possible associated postoperative complications, such as wound infections and hyperglycaemia, in patients who underwent lobectomy…
- Conditions
- Dexamethasone Adverse Reaction, Postoperative Pain, Postoperative Thoracic Procedure Complication, Analgesia
- Trial name
- NCT04325984
- Testing
- Dexamethasone
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- University of Trieste
Postoperative Shivering
Dexemedetomidine on Shivering Cesarean Section Under Spinal Anesthesia A Randomized Clinical Trial
Participants will examine dexemedetomidine versus dexamethasone on postoperative shivering after spinal anesthesia for caesarean section
- Trial name
- NCT05952752
- Testing
- giving dexemedetomidine 12 microgram Iv dripping, Dexamethsone IV
- Where
- Egypt
- Volunteers
- 382 people
- Sponsor
- Assiut University
Postoperative Nausea and Vomiting
The Effect of Ginger and Peppermint on Postoperative Nausea and Vomiting in Patients After Thyroid Surgery
The study was planned as a randomized controlled experimental study to determine the effect of inhalation use of ginger and peppermint on postoperative nausea and vomiting in patients undergoing thyroidectomy surgery.
- Trial name
- NCT04874298
- Testing
- Ginger, Peppermint
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Sona PASHAEI