Clinical trials: Post-operative Pain Control
Post Operative Pain
Analgesic Effect of M-TAPA and TAPB on Laparoscopic Cholesistectomy
Cholecystectomy is the most frequently performed abdominal surgery in developed nations, with laparoscopic cholecystectomy being recognized as the gold standard technique for treating gallstones.
- Trial name
- NCT06662617
- Testing
- modified thoracoabdominal nerve block through perichondrial approach, Transversus Abdominal Plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Root Canal Treatment, Post Operative Pain
A First in Human Study to Compare Feasibility of Inertial Cavitation Irrigation to SNI in Root Canal Treatment.
The study design is a single-center 2-arm randomized controlled clinical trial. 10 subjects (teeth) requiring a root canal treatment will be enrolled in 2 groups (5 in each group).
- Trial name
- NCT05374434
- Testing
- Conventional irrigation, Inertial cavitation
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lumendo AG
Arthropathy of Hip
Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty
The goal of this retrospective chart review is to evaluate if the implementation of lumbar plexus block placement for postoperative pain have improved conditions in the postoperative period for patients undergoing total hip…
- Trial name
- NCT02493621
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Endodontically Treated Teeth, Post Operative Pain
Bioceramics Pain Control
Postoperative pain in endodontic retreatment cases presents a challenge to any endodontist. Tricalcium silicate materials as mineral trioxide aggregate (MTA) and bioceramics have shown favorable periapical tissue reactions and…
- Trial name
- NCT05399303
- Testing
- obturation
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Misr International University
Total Knee Arthroplasty
Ultrasound-guided Continuous Proximal Adductor Canal vs Continuous Femoral Nerve Block for Postoperative Pain Control and Rehabilitation Following Total Knee Arthroplasty
The purpose of the study is to compare continuous femoral nerve block with continuous proximal adductor canal block for postoperative pain control and rehabilitation.
- Trial name
- NCT02495805
- Testing
- Continuous proximal adductor canal block, Continuous femoral nerve block
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Post-operative Analgesia
Bilateral Ultrasound Guided ESP Block Versus TAP Block on Post-operative Analgesia After Total Abdominal Hysterectomy
Abdominal hysterectomy is an open surgical procedure associated with considerable post-operative pain. Narcotics are often required during patient recovery but can result in adverse side effects.
- Trial name
- NCT03965156
- Testing
- 1) Ultrasound guided Erector spinae block, Ultrasound guided transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pain
Ear Acupuncture for Pain Associated With Ambulatory Arthroscopic Knee Surgery
The investigators propose to complete a randomized controlled trial to compare ear acupuncture at Cingulate gyrus, thalamus, omega 2, shen-men, and point zero on the right and left ear plus standard of care versus standard of…
- Trial name
- BFAKnee (NCT01447329)
- Testing
- Ear Acupuncture, Standard Treatment
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Mike O'Callaghan Military Hospital
Choroidal Melanoma, Melanoma
Pain Relief - Tramadol Versus Ibuprofen
The purpose of this study is to assess post operative pain following the insertion of radioactive plaque for choroidal melanoma in patients after receiving either ibuprofen or tramadol.
- Conditions
- Choroidal Melanoma, Melanoma, Eye Neoplasms
- Trial name
- NCT00111046
- Testing
- Ibuprofen, Tramadol
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Royal Liverpool University Hospital
Pain, Postoperative
Fentanyl Ultra Low Doses Effects on the Nociceptive Threshold
Exaggerated pain and hyperalgesia are major issues after surgery and can lead to chronic pain. Opioid are parts of pain sensitization processes but remain absolutely necessary in the intraoperative period.
- Trial name
- FENTANULD (NCT00454259)
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Shoulder Pain
Lavage and Suction of the Right Upper Quadrant to Reduce Post Laparoscopic Shoulder Pain
The use of laparoscopy in gynecologic surgery has been well established to decrease morbidity, blood loss, hospital stay, and post-operative pain when compared to traditional open abdominal surgery.
- Trial name
- NCT02004470
- Testing
- Active lavage and suction
- Where
- 4 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Knee Osteoarthritis, Knee Pain Chronic
iPACK Block for Total Knee Arthroplasty
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the rehabilitation process of the Interspace between the Popliteal Artery and Capsule of the Posterior Knee (iPACK) block in total knee…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT06087562
- Testing
- Ropivacaine 0.5% Injectable Solution 20mL, 0,9% normal saline 20mL
- Where
- Poland
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Post Operative Pain
Comparison Between Two Instrumentation Techniques on Postoperative Pain and Level of Neuropeptides
General aim: assessment of post operative pain and time of preparation with the execution of manual-less technique and conventional technique.
- Trial name
- NCT07357233
- Testing
- Manual-less, Conventional technique
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Post Operative Pain
Pre-incision Versus Lapaorscopic-assisted Transversus Abdominis Plane (TAP) and Rectus Sheath Block for Post-Cholecystectomy Pain
The goal of this clinical trial is to compare pre-incision vs laparoscopic assisted Transversus abdominis plane and rectus sheath block in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT05856682
- Testing
- Laparoscopic-assisted TAP block(LATAP) and Rectus Sheath block
- Where
- Pakistan
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Patel Hospital, Pakistan
Rotator Cuff Tear, Pain, Postoperative
Single Shot Liposomal Bupivicaine in Rotator Cuff Surgery
This document is a protocol for a human research study. This study is to be conducted according to United States standards of Good Clinical Practice in accordance with applicable Federal regulations and institutional research…
- Trial name
- NCT03822182
- Testing
- liposomal bupivicaine, Dexamethasone
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Indiana University
Post Operative Pain
Opioid Analgesic Reduction Study (OARS) - Pilot
The purpose of this study is to test protocols being developed for the conduct of a large sale multi-site clinical trial which will compare opioids to non-opioids for managing post-surgical impacted 3rd molar extraction pain.
- Trial name
- OARS-Pilot (NCT05283499)
- Testing
- OPIOID, NON-OPIOID
- Where
- 5 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Pain, Postoperative
Cesarean Delivery and Post-operative Pain Management With Local Anesthesia
The use of .5% Bupivacaine with epinephrine at the time of skin closure in cesarean deliveries will decrease post-op pain.
- Trial name
- NCT00298571
- Testing
- .5% bupivacaine with epinephrine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Analgesia, Pain, Post Operative
Comparison of OSTAP and EOIP Blocks in Laparoscopic Cholecystectomies
Laparoscopic cholecystectomy (LC) surgery causes postoperative severe pain. As part of multimodal analgesia aimed at reducing postoperative opioid consumption and providing effective analgesia, ultrasound (US)-guided transversus…
- Trial name
- NCT06172465
- Testing
- EOIP, OSTAP
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samsun University
Opioid Use, Post-operative Pain
Opioid Use After Laparoscopic Salpingectomy
The purpose of this study is to evaluate patient-reported post-operative pain scores following minimally invasive tubal sterilization procedures to determine if a multimodal, non-opioid pain control regimen is non-inferior to a…
- Conditions
- Opioid Use, Post-operative Pain, Sterility, Female
- Trial name
- NCT06434233
- Testing
- Acetaminophen, Ibuprofen, Oxycodone
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Liposomal Bupivacaine
Exparel Versus Bupivacaine in Post-operative Pain Control
This is a prospective, randomized study to evaluate anaesthetic parameters, postoperative analgesia and oral analgesic consumption comparing exparel (liposomal bupivacaine) vs. standard bupivacaine
- Trial name
- NCT06547255
- Testing
- Bupivacaine liposome injectable suspension
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Pain, Post Operative Pain
Erector Spinae Plane Block for Postoperative Pain Management
Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles.
- Trial name
- NCT05697315
- Testing
- Control, Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University