Clinical trials: Post-operative Pain Control
Pregnancy
Comparative Study of Ropivacaine and Ropivacaine With Dexmeditomedine in TAP Blocks
Comparative study of Ropivacaine and Ropivacaine with dexmedetomidine in transversus abdominis plane (TAP) block for post-operative analgesia in patients undergoing Caesarean Section.
- Trial name
- NCT02472522
- Testing
- Ropivacaine + Dexmedetomidine, Ropivacaine
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Tata Main Hospital
Post Operative Pain
Postoperative Anelgesic Effect of Rhomboid Intercostal Nerve Block Versus Erector Spinae Plane Block
Despite of analgesic effect of intravenous analgesic medications at intraoperative and postoperative time , The regional anesthetic techniquehas more benefits suchbetter control of Acute pain and hence less chronic pain and…
- Trial name
- NCT05452369
- Testing
- Rhomboid intercostal plane block
- Where
- 2 sites in Egypt
- Volunteers
- 104 people
- Sponsor
- ghada fouad
Post Operative Pain, Opioid Analgesic Adverse Reaction
Postoperative Analgesia Intervention With Non-opioid Alternatives (PAIN-Alt) Trial - Breast Surgery
North America is experiencing a crisis of opioid use and abuse, partially caused by excessive prescribing by doctors. People often receive their first opioid prescription for pain treatment after outpatient breast surgery (i.e.…
- Conditions
- Post Operative Pain, Opioid Analgesic Adverse Reaction, Surgery, Postoperative Pain
- Trial name
- PAIN-Alt (NCT06507345)
- Testing
- Opioid Analgesia (OA) [Multimodal analgesia including opioid drugs], Opioid-Free Analgesia (OFA) [Multimodal analgesia not including opioid drugs]
- Where
- Canada
- Volunteers
- 540 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pain
Post-operative Pain Management In Patients Undergoing Hullax Valgus Surgery
The purpose of this study is to investigate the efficacy and cost analysis of intravenous fentanyl combined with either local anesthesia infiltration or peroneal nerves block in patients with Hallux Valgus undergoing orthopedic…
- Trial name
- NCT01960595
- Testing
- IV fentanyl PCA, local bupivacaine infiltration and post-OP IV fentanyl PCA, Nerve Blocks and post-OP IV fentanyl PCA
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Post Operative Pain
Comparison of Ultrasound-Guided Continuous Erector Spinae Plane Block Versus Thoracic Epidural Analgesia
There are limited studies comparing these two modalities ( thoracic epidural and erector spine block) for relieving the pain after thoracic surgeries .this study aim to investigate this purpose
- Trial name
- TEAVSESPB (NCT06571188)
- Testing
- THORACIC EPIDURAL BLOCK, ERECTOER SPINE BLOCK
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Menoufia University
Postoperative Pain
Evaluation of Postoperative Pain Following Bascom Cleft Lift Operation
The purpose of this study is to evaluate postoperative pain in Bascom Cleft Lift operation receiving multimodal analgesia in day-case surgery setting.
- Trial name
- NCT02196727
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Hvidovre University Hospital
Post Operative Pain, Inguinal Hernia
Comparison of Two Different Analgesic Regional Block Techniques in Pediatric Patients Undergoing a Hernia Repair
Lower abdominal operations; especially inguinal hernia repairs are one of the most frequently performed operations in the daily practice of pediatric surgeries.Regional anesthesia techniques are frequently and effectively used…
- Trial name
- NCT05896072
- Testing
- Erector Spinae Plane Block, Caudal Block
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Abant Izzet Baysal University
Pain, Postoperative, Osteoarthritis
Pain Treatment After Total Knee Replacement - Continuous Epidural Versus Intravenous Patient Controlled Analgesia With Morphine
The study purpose is to compare the effectiveness of different methods for post-operative pain treatment after total knee replacement.
- Trial name
- NCT00270322
- Testing
- Marcaine 0.166% + Fentanyl 3.33 mcg/ml, Morphine sulphate
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rambam Health Care Campus
Total Knee Arthroplasty (Postoperative Pain)
Phase 2B Study Assessing Pain Relief After Replacement of the Knee
The goal of the ATX101-TKA-004 clinical trial aims to evaluate the efficacy and safety of ATX101 1,500 mg in participants undergoing primary unilateral total knee arthroplasty.
- Trial name
- SPARK2 (NCT06799845)
- Testing
- ATX101, bupivacaine hydrochloride
- Where
- 11 sites in United States
- Volunteers
- 226 people
- Sponsor
- Allay Therapeutics, Inc.
Pain
Betamethasone to Control Postoperative Pain in Emergency Endodontic Care
The objective of this randomized double-blind study was to evaluate the effect of betamethasone in the control of postoperative pain in patients undergoing endodontic treatment.
- Trial name
- NCT02865746
- Testing
- Bethametasone
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Acupuncture, Pain, Postoperative
Acupuncture for Vasectomy Pre-procedural Anxiety and Pain Control in the Primary Care Setting
This study compares auricular (ear) acupuncture and body acupuncture (Koffman protocol) versus clinic standardized pre-vasectomy medications to determine which has better outcomes at improving pre-procedural anxiety and…
- Conditions
- Acupuncture, Pain, Postoperative, Vasectomy
- Trial name
- NCT03938415
- Testing
- Acupuncture, Standardized pre-procedure medications
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Matthew Snyder
Postoperative Pain
Oral Versus Intravenous Acetaminophen in Lumbar Spine Surgery
The goal of this study is to compare whether oral or intravenous acetaminophen works better for pain control in patients undergoing lumbar spine fusion surgery
- Trial name
- NCT07203079
- Testing
- Acetaminophen Oral Tablet, Acetaminophen infusion
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Stanford University
Postoperative Pain, Breast Cancer
Administration of Ketamine to Prevent the Post-operative Pain
The surgery of breast cancer is responsible for post-operative pain, needing in about 30% some morphine consumption; like that, the association of ketamine with general anaesthesia may decrease morphine's use and so its adverse…
- Trial name
- KETAMINE (NCT00210210)
- Testing
- Ketamine, Saline solution
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Institut Bergonié
Obesity, Bariatric Surgery
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Conditions
- Obesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Acute Post Operative Pain
- Trial name
- NCT06515691
- Testing
- M-TAPA block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Post Operative Pain, Total Knee Replacement
Comparative Pain Control Between 0.2 or 0.3 Spinal Morphine and 0.25 or 0.5 % Bupivacaine for FNB After TKA
Comparative efficacy of 24 and 48 hours post operative pain control in single total knee replacement between intrathecal bupivacaine with 0.2 or 0.3 mg morphine together with 0.25 or 0.5 % bupivacaine for single femoral nerve…
- Trial name
- NCT00795223
- Testing
- morphine and bupivacaine, spinal morphine and marcaine
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Postoperative Pain
Local Infiltration With Ropivacaine Improves Postoperative Pain Control in Patients
The purpose of this study is to evaluate the effect of pain relief after infusion of ropivacaine at port sites at end of laparoscopic cholecystectomy (LC)compared with placebo (0.9% normal saline).
- Trial name
- NCT02649179
- Testing
- Ropivacaine, 0.9% saline
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Air Force Military Medical University, China
Root Canal Treatment, Irreversible Pulpitis With Apical Periodontitis
Effect of Probiotics, Double Antibiotic Paste, and Calcium Hydroxide on Postoperative Pain in Irreversible Pulpitis: A Randomized Trial
The goal of this clinical trial is to learn whether probiotics, double antibiotic paste (DAP), or calcium hydroxide paste help reduce postoperative pain after root canal treatment in adults with symptomatic irreversible pulpitis.
- Conditions
- Root Canal Treatment, Irreversible Pulpitis With Apical Periodontitis, Pulpitis - Irreversible, Post Operative Pain, Acute
- Trial name
- NCT07270159
- Testing
- Probiotic
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Local Analgesia Via Nerve Block
A Study of Bupivacaine Liposome Injection in the Treatment of Pain After Thoracoscopic Surgery
The objective of this study is to evaluate the efficacy, safety, and tolerability of bupivacaine liposomes for paravertebral nerve block in the treatment of thoracoscopic postoperative pain, and to evaluate the relevant human…
- Trial name
- NCT06529432
- Testing
- Bupivacaine Liposome Injection, Bupivacaine Hydrochloride Injection
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Post Operative Pain
Effect of Preoperative Information About Pain on Postoperative Pain Experience and Patient Satisfaction
Patients are randomized into 2 groups. The intervention group which receives preoperative counseling about pain and a control group which does not receive this counseling.
- Trial name
- epps (NCT03056521)
- Testing
- preoperative information about pain
- Where
- Uganda
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Makerere University
Pain, Postoperative
Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery
This study will compare IV (intravenous) versus oral (PO) acetaminophen for postoperative pain after scheduled, elective Cesarean delivery.
- Trial name
- NCT02487303
- Testing
- Acetaminophen Intravenous, Acetaminophen Oral
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina