Clinical trials: Post-operative Pain Management
Chronic Pain, Cesarean Section Complications
Reducing Chronic Pain Following Cesarean Delivery
This pilot study will evaluate the feasibility and acceptability of delivering Empowered Relief (ER), a single-session pain relief skills class, to postpartum women with ongoing pain and/or pain interference following cesarean…
- Conditions
- Chronic Pain, Cesarean Section Complications, Postpartum
- Trial name
- NCT07799883
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Postoperative Pain, Quality of Recovery
SPSIPB vs. SAPB in Breast Surgery
The effects of the newly defined serratus posterior superior intercostal plane block and serratus anterior plane block on postoperative analgesia and quality of recovery in women undergoing breast surgery will be investigated.
- Trial name
- NCT06948383
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Serratus Anterior Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Postoperative Pain Management
Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine
The investigators are evaluating postoperative outcomes in patients undergoing hip replacement surgery performed with either spinal or general anesthesia, who also receive a suprainguinal fascia iliaca block using either…
- Trial name
- NCT07316166
- Testing
- Dexmedetomidine, Ropivacaine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Rhode Island Hospital
Postoperative Pain, Cryptorchidism
Comparison of Posterior QLB and QIPB in Pediatric Undescended Testis Surgery.
This randomized, double-blind study compares the postoperative analgesic efficacy of ultrasound-guided Posterior Quadratus Lumborum Block (QLB) versus Quadroiliac Plane Block (QIPB) in pediatric patients aged 1-7 years undergoing…
- Trial name
- NCT07426796
- Testing
- Ultrasound-guided Posterior Quadratus Lumborum Block., Ultrasound-guided Quadroiliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Medipol University
Bilateral Total Knee Arthroplasty
Efficacy of Pain Control in Different Bupivacaine Dose in Periarticular Injection in Bilateral Total Knee Arthroplasty
To study efficacy of postoperative pain control of different concentrations of bupivacaine for periarticular infiltration, part of multimodal analgesia, in bilateral total knee arthroplasty.
- Trial name
- NCT03249662
- Testing
- bupivacaine 200 mg, bupivacaine 100 mg
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Postoperative Analgesia
Effectiveness of Interscalene Brachial Plexus Block and Intra-articular Injection of Ropivacaine for Post-operative Analgesia in Arthroscopic Shoulder Stabilization Surgery
This study evaluates two anaesthetic techniques namely interscalene brachial plexus block and intra-articular local anaesthetic injection.
- Trial name
- NCT01589354
- Testing
- Interscalene brachial plexus block, Intra-articular Ropivacaine injection, Ultrasound guided technique
- Volunteers
- 60 people
- Sponsor
- NHS Grampian
Pain, Postoperative, Osteoarthritis
Pain Treatment After Total Knee Replacement - Continuous Epidural Versus Intravenous Patient Controlled Analgesia With Morphine
The study purpose is to compare the effectiveness of different methods for post-operative pain treatment after total knee replacement.
- Trial name
- NCT00270322
- Testing
- Marcaine 0.166% + Fentanyl 3.33 mcg/ml, Morphine sulphate
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rambam Health Care Campus
Postoperative Pain Management
Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Hysterectomy
To compare the effects of intravenous paracetamol and ibuprofen on postoperative pain and morphine consumption in patients undergoing hysterectomy surgery and the side effects associated with opioids.
- Trial name
- ibupro-hyst (NCT04691856)
- Testing
- Morphine Sulfate, Intravenous paracetamol, Intravenous ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Inonu University
Tonsillitis, Airway Obstruction
Acetaminophen's Efficacy For Post-operative Pain
The purpose of this study is to compare IV acetaminophen to oral acetaminophen for pain control in children undergoing tonsillectomy with or without adenoidectomy.
- Conditions
- Tonsillitis, Airway Obstruction, Difficulty Swallowing
- Trial name
- NCT01721486
- Testing
- IV acetaminophen, PO acetaminophen
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Kaveh Aslani, MD
Head and Neck Cancer, Free Tissue Transfer
Local Infusion of Ropivacaine for Post-Op Pain Control After Osseocutaneous Free Flaps
Head and neck oncologic surgery often requires the use of free tissue transfer, or microvascular reconstruction, to reconstruct defects created by tumor resections.
- Trial name
- NCT03349034
- Testing
- Ropivicaine, Local Saline Infusion
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gastric Cancer
Comparison of Ropivacaine-Poloxamer 407 Hydrogel and TAP Block for Postoperative Pain Management in Laparoscopic/Robotic Gastrectomy
This study aims to determine whether Ropivacaine-Poloxamer 407 hydrogel provides non-inferior pain control compared to TAP block for patients undergoing minimally invasive gastrectomy.
- Trial name
- NCT06839716
- Testing
- Arm I (Ropivacaine-Poloxamer 407 hydrogel group), Arm II (TAP block group)
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- Gangnam Severance Hospital
Hypospadias Repair, Pediatric Anesthesia
Caudal vs Dorsal Penile Nerve Block for Postoperative Analgesia in Children Undergoing Hypospadias Repair (CaD-DPNB)
This prospective, randomized clinical trial conducted at Ain Shams University Hospitals evaluated the analgesic efficacy of dorsal penile nerve block versus caudal epidural block in 30 male children undergoing primary hypospadias…
- Conditions
- Hypospadias Repair, Pediatric Anesthesia, Postoperative Analgesia
- Trial name
- CaD-DPNB (NCT07306806)
- Testing
- Caudal epidural block, Dorsal Penile nerve Block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Post-op Pain
PO vs. IV Acetaminophen Given Perioperatively for 24 hr Post-op Pain Control Following Total Hip or Knee Replacement
The purpose of the study is to evaluate post-op pain requirements in patients undergoing hip or knee replacement surgery who perioperatively receive either Oral acetaminophen or IV acetaminophen
- Trial name
- KHEA (NCT02244619)
- Testing
- Oral acetaminophen, IV acetaminophen
- Where
- United States
- Volunteers
- 515 people
- Sponsor
- Kettering Health Network
Pain, Postoperative
Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management
Effective post surgical pain control in patients undergoing unilateral deep inferior epigastric perforator (DIEP) free flap reconstruction.
- Trial name
- NCT04284930
- Testing
- Depobupivacaine, OnQ pump, 0.25% Bupivacaine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The Cleveland Clinic
Post Operative Pain
Bupivacaine With Dexmedetomidine Versus Bupivacaine Alone for Transversus Abdominis Plane Block in Caesarean Section
Transversus Abdominis plane (TAP) block is a regional technique for providing analgesia of the anterolateral abdominal wall. TAP block are commonly given in patients who have undergone various abdominal as well as pelvic…
- Trial name
- NCT06292273
- Testing
- Transversus Abdominis Plane Block with bupivacain Plus dexamethasone, Transversus Abdominis Plane Block with bupivacain
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Opioid Use
Opioid Analgesic Reduction Study
The goal is to provide health care professionals, including dentists, with the best possible evidence for clinical decision making when deciding upon analgesics for acute post-surgical pain management, a double-blind, stratified…
- Trial name
- OARS (NCT04452344)
- Testing
- opioid-containing analgesic, two over-the-counter analgesics
- Where
- 5 sites in United States
- Volunteers
- 1,815 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Spinal Fusion, Adolescent Idiopathic Scoliosis
Low Dose Dexmedetomidine as a Postoperative Pain Adjunct
This randomized controlled trial examines whether the addition of a low-dose dexmedetomidine infusion to our current multimodal pain management plan decreases narcotic consumption and reduces side effects in adolescent patients…
- Trial name
- NCT06067893
- Testing
- Dexmedetomidine, Normal Saline
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nichole Doyle
Analgesia, Surgery
Evaluation of the Added Value of Metamizole to Standard Post-operative Treatment After Ambulant Surgery
The aim of this study is to investigate if the addition of metamizole to the standard post-operative treatment, i.e. paracetamol and ibuprofen, is superior in reducing post-operative pain on day 1 after ambulatory surgery…
- Conditions
- Analgesia, Surgery, Recovery
- Trial name
- NCT04082728
- Testing
- Metamizole
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- Jessa Hospital
The Effect of Preoperative Administration of Oral Tizanidine, Post Operative Pain
The Effect of Preoperative Administration of Oral Tizanidine on the Postoperative Pain and Sleep Quality
The majority of lower limb fractures treated with surgery often leading to significant morbidity and mortality. Despite improvements in perioperative care, about 20% suffer from severe postoperative complications.
- Trial name
- Tizanidine (NCT07800364)
- Testing
- Tizanidine
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Tanta University
Postoperative Pain, Abdominal Aortic Aneurysm
Pain Control After Aortic EndoaneurYsmEctomy (POPEYE)
Open abdominal aortic aneurysm repair (OR-AAA) is an operation associated with high morbidity, and has 30-day mortality rates of between 4 and 14%. Post-operative pain management represents a primary anesthetic focus.
- Trial name
- POPEYE (NCT06244732)
- Testing
- Postoperative pain control
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Policlinico S. Donato
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.