Clinical trials: Post-operative Pain Management
Analgesia, Post-Operative Pain
A Prospective Pilot Study of a Non-Narcotic Post-Operative Course After Colectomy
With this pilot investigation, the investigators aim to challenge the reliance on opiate analgesia following colon and rectal surgery.
- Conditions
- Analgesia, Post-Operative Pain, Breakthrough Pain, Colectomy
- Trial name
- NCT05200806
- Testing
- Non-Narcotic ERAS Post-Operative Pain Management
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Hernia, Inguinal, Post Operative Pain
Herniorrhaphy for Postoperative Pain
Subjects receive either CPL-01, positive control, or negative control after herniorrhaphy and are then followed.
- Trial name
- NCT05813847
- Testing
- local anaesthetic injection of CPL-01, Morphine (rescue medication), Acetaminophen (rescue medication)
- Where
- United States
- Volunteers
- 518 people
- Sponsor
- Cali Pharmaceuticals LLC
Anxiety, Postoperative Pain
Sublingual Melatonin for Anxiety and Pain in Elective Gynecologic Surgery
This prospective randomized controlled study aims to evaluate the anxiolytic effect of preoperative sublingual melatonin and its impact on postoperative pain scores when administered in two different doses to female patients…
- Conditions
- Anxiety, Postoperative Pain, Anesthesia
- Trial name
- NCT06997263
- Testing
- Melatonin 3 mg Sublingual, Melatonin 6 mg Sublingual
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Benha University
Postoperative Pain Management
COMPARISON OF THE EFFECTS OF ERECTOR SPINAE PLANE (ESP) BLOCK AND QUADRO İLİAC PLANE (QIP) BLOCK ON POSTOPERATIVE OPIOID CONSUMPTION AND PAIN IN LUMBAR SPINAL SURGERY
COMPARISON OF THE EFFECTS OF ERECTOR SPINAE PLANE (ESP) BLOCK AND QUADRO İLİAC PLANE (QIP) BLOCK ON POSTOPERATIVE OPIOID CONSUMPTION AND PAIN IN LUMBAR SPINAL SURGERY
- Trial name
- NCT07852104
- Testing
- NRS Score, total tramadol consumption, Post Operative Pain Relievers
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Aydin Adnan Menderes University
Postoperative Pain
Surgical Nurses' Pain Management Self-Efficacy and Patients' Postoperative Pain Outcomes
This study examines whether surgical nurses' confidence in managing patients' pain (pain management self-efficacy) is related to how well their patients' pain is managed after surgery.
- Trial name
- NCT07830498
- Testing
- Pain Management Self-Efficacy and Postoperative Pain Outcome Assessment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Volkan Gokmen
Post Operative Analgesia, Rebound Pain
Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block (REBOUND)_part A
Rebound pain after peripheral nerve blocks reduces the benefits of regional anesthesia and increases opioid consumption. This rebound pain most likely results from suboptimal pain management, as patients receiving a peripheral…
- Conditions
- Post Operative Analgesia, Rebound Pain, Post Operative Pain, Acute
- Trial name
- REBOUND (NCT07666971)
- Testing
- Morphine provided via oral PCA, Morphine provided via oral PCA + morphine administered at a scheduled regimen
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Pain Management
Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain
Bupivacaine is the most widely used local anesthetic agent across majority of the Cardiac Implantable Electronic device (CIED) implant procedures in the United States.
- Trial name
- NCT05575999
- Testing
- Bupivacaine alone OR Bupivacaine-Ketorolac-Ketamine (BKK) Combination
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Peripheral Arterial Occlusive Disease
Interest of a Bi-truncal Nerve Block (Femoral + Sciatic) Extended, Systematically Associated With General Anesthesia, in the Femoropopliteal Bypass: Study of Post-operative Analgesia and Peripheral Circulation Downstream
The aim of this study is to assess, in patients scheduled for femoropopliteal bypass, the benefit of a double peripheral nerve block (femoral + sciatic) with levobupivacaine and clonidine in a single dose, performed before…
- Trial name
- BLOC-FEMPOP (NCT01785693)
- Testing
- levobupivacaine, clonidine
- Where
- France
- Volunteers
- 47 people
- Sponsor
- University Hospital, Clermont-Ferrand
Postoperative Analgesia
Adductor Canal Block With IPACK Versus Genicular Nerves Block With IPACK for Post-operative Analgesia
In our study, we will find out the efficacy of those peripheral nerve blocks on postoperative pain in knee arthroscopy. The aim is to evaluate the efficacy of combined ultrasound-guided IPACK with adductor canal nerve block…
- Trial name
- IPACK (NCT07258277)
- Testing
- IPACK with adductor canal block, IPACK with Genicular nerves block, Spinal Block
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Minia University
Hemorrhoids, Postoperative Pain
Oral Nifedipine Versus Placebo for Pain and Healing After Hemorrhoidectomy
The goal of this clinical trial is to evaluate whether oral nifedipine reduces postoperative pain and improves wound healing after hemorrhoidectomy in adult patients aged 18-65 years undergoing elective surgery for grade III or…
- Conditions
- Hemorrhoids, Postoperative Pain, Wound Healing, Analgesia
- Trial name
- NIFEDIPINE-HD (NCT07659665)
- Testing
- Nifedipine 20 Mg
- Where
- Yemen
- Volunteers
- 100 people
- Sponsor
- Sana'a University
Pain, Post Operative Pain
Erector Spina Plane Block for Multilevel Major Spinal Surgery
Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles.
- Trial name
- NCT05983393
- Testing
- Erector spinae plane block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Postoperative Pain
Surgicel and Analgesic Reservoir
Laparoscopic cholecystectomy (LC) is a widespread surgical procedure with superior outcomes in terms of the incurred postoperative pain, recovery time, cosmetic, and morbidity issues.
- Trial name
- NCT03730714
- Testing
- "Local Anesthetic", "Epinephrine" and "Morphine", "Local Anesthetic", "Epinephrine", "Morphine" and "Surgicel", "Normal Saline"
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Laparoscopic Cholecystectomy, Post Operative Analgesia
Postoperative Pain After Instillation Of Bupivacaine During Laparoscopic Cholecystectomy
This study aims to compare the level of postoperative pain experienced by patients undergoing laparoscopic cholecystectomy with and without the use of intraperitoneal bupivacaine.
- Conditions
- Laparoscopic Cholecystectomy, Post Operative Analgesia, Bupivacaine
- Trial name
- BUPA-LC (NCT07098429)
- Testing
- Bupivacain (Postoperative), Normal (0.9%) saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh
Postoperative Pain
A Safety and Effectiveness Study of SABER®-Bupivacaine for Pain Following Shoulder Surgery
This is a research study testing SABER-Bupivacaine (an experimental pain-relieving medication). SABER-Bupivacaine is designed to continuously deliver bupivacaine, a common local anesthetic, for a few days in order to treat local…
- Trial name
- NCT00818363
- Testing
- SABER-Bupivacaine
- Where
- 9 sites in Australia, New Zealand
- Volunteers
- 60 people
- Sponsor
- Durect
Post Operative Pain
Superior Trunk Block Applied for Upper Arm Surgery
Nerve blocks applied with ultrasonography are currently used for many post-operative pain and operations. Providing adequate area analgesia is the primary goal of clinicians, as early mobilization is suggested after shoulder and…
- Trial name
- NCT05474014
- Testing
- superior trunk block, intravenous patient-controlled analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Analgesia, Post Operative Pain
Morphine vs Sufentanil PCA: Same Same or Different?
Patient-controlled intravenous analgesia (PCA) has already proven its quality. However, with new strategies starting to emerge and the current concept of opioid sparing, it is a goal to find the optimal PCA strategy capable of…
- Conditions
- Analgesia, Post Operative Pain, Patient Satisfaction, Chronic Pain
- Trial name
- NCT05259098
- Testing
- Sufentanil Sublingual Tablet System, Intravenous Patient-Controlled Analgesia with morfine
- Where
- Portugal
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital Central do Funchal
Anesthesiology, Orthopedic
PO Pain Management With Extended-release Dinalbuphine Sebacate in Patients Undergoing Arthroscopic Shoulder Surgery
Postoperative pain is common, and the pain intensity can be moderate to severe depending on the site of surgery during the first few days after surgery, and an estimated 15% to 45% experience chronic postsurgical pain.
- Trial name
- NCT05115955
- Testing
- DS group, Control group
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Postoperative Pain Management
Intravenous Lidocaine and Postoperative Pain Management
This study was to evaluate the effect of intraoperative intravenous lidocaine on postoperative pain management after laparoscopic cholecystectomy.
- Trial name
- NCT02997215
- Testing
- Lidocaine
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Tongren Hospital
Post Operative Pain
Preemptive Acetaminophen for Postoperative Pain Control Following Minimally Invasive Hysterectomy
This study is investigating whether administration of acetaminophen the day before surgery improves post operative pain following minimally invasive hysterectomy.
- Trial name
- NCT04360135
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children
Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population
The goal of this randomized clinical trial is to determine if administration of Exparel via local infiltration for medial patellofemoral ligament (MPFL) reconstruction procedures in pediatric orthopaedic sports medicine patients…
- Conditions
- Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Trial name
- NCT06559215
- Testing
- Exparel
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Texas Scottish Rite Hospital for Children
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