Clinical trials: Post-operative Pain Management
Post-operative Pain, Post-operative Nausea and Vomiting
Multimodal Perioperative Pain Management: ComfortSafe Program
Proposed is a demonstration project to characterize the immediate, short-term and long-term pain and other post-operative outcomes of 60, self-selected breast (n=20), caesarian-section (n=20) and abdominal (n=20) surgical…
- Conditions
- Post-operative Pain, Post-operative Nausea and Vomiting, Respiratory Depression, Confusion Postoperative
- Trial name
- NCT04046068
- Testing
- ComfortSafe Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Georgetown University
Analgesia
Nociception Level During Opioid-sparing Anaesthesia Versus Conventional Opioid-based Anaesthesia
The aim of this double blind, randomised controlled non-inferiority trial is to compare the antinociceptive efficiency of an opioid-sparing and a conventional opioid-based anaesthesia protocol with the help of the CEcertificated…
- Trial name
- NOL_Basel (NCT05485480)
- Testing
- conventional opioid-based group, opioid-sparing group
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University Hospital, Basel, Switzerland
Abdominal Surgery, Thoracic Surgery
Parent/Nurse Controlled Analgesia in the Neonatal Intensive Care Unit
The aim of this study is to examine the safety and effectiveness of 2 morphine delivery systems for post-surgical neonates. The investigators hypothesize that this study will be feasible to conduct, and that neonates receiving…
- Trial name
- PNCA (NCT01823497)
- Testing
- Morphine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Medical College of Wisconsin
Post Operative Pain
Post-Operative Kinesio Taping Impact on Pain in Thoracotomy vs Thoracoscopy
The project is of a comparative nature. It seeks to study pain reduction following two forms of chest surgery and compare results between both procedures. It will use kinesio taping as the studied pain reducer.
- Trial name
- NCT05200689
- Testing
- Kinesiotaping (KT)
- Where
- 5 sites in Egypt, Italy and 2 more
- Volunteers
- 310 people
- Sponsor
- Al-Quds University
Post Operative Pain
Systemic Lidocaine Infusion for Pain Control in Ventral Hernia
Ventral hernia repair leads to more than expected pain. This is thought to be secondary to nerve pain at the lateral transfixion sutures. Systemic lidocaine given pre-op has in other situations decreased neurogenic pain.
- Trial name
- NCT03484650
- Testing
- Lidocaine Hydrochloride
- Where
- United States
- Sponsor
- Carilion Clinic
Pain, Postoperative
Erector Spinae Plane Block in Liver Transplantation Donors
Living donor liver transplantation has become a common treatment option for patients with end-stage liver disease. Donor hepatectomy is associated with significant postoperative pain due to inverted L-shaped incision.
- Trial name
- NCT05406388
- Testing
- Erector Spinae Plane Block, Intravenous fentanyl patient control device
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medipol University
Pain, Postoperative, Brachial Plexus Block
Liposomal Bupivacaine Single-Injection Interscalene Block vs. Continuous Interscalene Block for Primary Total Shoulder Arthroplasty
This study aims to assess analgesia efficacy between liposomal bupivacaine single injection interscalene blockade vs. continuous interscalene nerve block for patients undergoing primary total shoulder arthroplasty.
- Trial name
- NCT05005260
- Testing
- Bupivacaine HCl, Liposomal bupivacaine + Bupivacaine Hcl 0.5% Inj
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Mayo Clinic
Postoperative Pain
Method Study: Bilateral TAP Block With 24 Hours Infusion
The purpose of this method study in healthy volunteers is to determine the extent of sensory block following Transversus Abdominis Plane (TAP) block with 24 hours infusion of ropivacaine versus infusion of saline.
- Trial name
- NCT01577940
- Testing
- Infusion of ropivacaine, Infusion of saline
- Where
- 2 sites in Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Shoulder Pain, Shoulder Disease
Interscalene Block vs Serratus Posterior Superior Intercostal Plane Block
Postoperative pain is important following arthroscopic shoulder surgery. Postoperative effective pain treatment provides early mobilization and a shorter hospital stay.
- Trial name
- NCT07278050
- Testing
- Erector spinae plane block, Serratus posterior superior intercostal plane block, Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Osteo Arthritis Knee
Post-op Ketamine Study
The purpose of this study is to establish the effect of sub-anesthetic dosing of ketamine with spinal anesthesia during total knee arthroplasty on post-operative pain and narcotic consumption.
- Trial name
- NCT03865550
- Testing
- Isotonic saline, Ketamine Injectable Solution
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Rothman Institute Orthopaedics
Post-operative Intercostal Neuralgia
Minocycline for the Prevention of Post-operative Intercostal Neuralgia
In about half the patients who have an open chest surgery there is persistent severe pain in the chest. The investigators are examining whether minocycline, a commonly used antibiotic, will prevent pain.
- Trial name
- NCT01314482
- Testing
- Minocycline
- Where
- Australia
- Volunteers
- 116 people
- Sponsor
- University of Adelaide
Erector Spinae Block
Erector Spinae Plane (ESP) Block For Postoperative Pain Management In Lumbar Spine Surgery
Lumbar vertebra surgery is one of the most common surgical procedures. After lumbar veretebra surgery, patients complain of excessive pain.
- Trial name
- NCT03997227
- Testing
- Erector spinae Block
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Aydin Adnan Menderes University
Post Operative Pain, Analgesia
Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years
During general anesthesia, objective monitoring for analgesia is still lacking. The administration of opioids relies on the experience of the anesthesiologist.
- Conditions
- Post Operative Pain, Analgesia, Children, Only, Narcotic Use
- Trial name
- NCT05758090
- Testing
- NIPE monitor, Control
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Khon Kaen University
Thoracic Surgery, Video-Assisted
Erector Spinae Plane Block For Analgesia Following Video-Assisted Thoracoscopic Surgery
Erector spinae (ESP) block is a recently described plane block designed to block the dorsal and ventral rami of the thoracic spinal nerves. It is meant to block the ipsilateral trunk.
- Trial name
- NCT03860480
- Testing
- ESP with Bupivacaine 0.5%, ESP with Saline 0.9%
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Hysterectomy, Post Operative Analgesia
Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use
The purpose of this study is to determine whether an injection of a local anesthetic (Bupivacaine with epinephrine) in the vaginal cuff prior to closure would result in less immediate postoperative pain medication and increase…
- Trial name
- NCT06719180
- Testing
- Bupivacain
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- MediSys Health Network
Post Thoracotomy Pain
The Pre-Emptive Administration Of Ketamine for Controlling Post-thoracotomy Pain
The goal of this paper is to evaluate whether the pre-emptive administration of Ketamine would potentiate the effect of intravenous morphine analgesia in management of post thoracotomy pain.
- Trial name
- NCT03415191
- Testing
- Ketamine, Normal Saline
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University of Campania Luigi Vanvitelli
Knee Osteoarthritis, Knee Injuries
Para-sartorial Compartment Block in Knee Surgery
Selective blockade of the saphenous nerve branches is among the regional anesthesia techniques in knee surgery. In this block, analgesia is provided without motor block and is an essential advantage in terms of early mobilization…
- Conditions
- Knee Osteoarthritis, Knee Injuries, Knee Disease, Knee Arthritis
- Trial name
- NCT05566561
- Testing
- Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Post Operative Pain
Comparative Study Between Ultrasound Guided Quadratus Lumborum Versus Ilioingunial/ Iliohypogastric Nerves Block as Post-operative Analgesia for Patients Undergoing Inguinal Hernia Repair Surgeries
Postoperative pain management is becoming an integral part of anesthesia care. Various techniques of pain relief have been designed.
- Trial name
- NCT06661707
- Testing
- Sonar guided Quadratus Lumborum block, Sonar guided Ilioinguinal/Iliohypogastric block
- Volunteers
- 44 people
- Sponsor
- Ain Shams University
Breast Cancer, Breast Neoplasms
Pectoral Nerve Block Type-II and Rhomboid Intercostal Block for Pain Management Following Mastectomy Surgery
Postoperative pain is an important issue in patients underwent mastectomy and axillary dissection surgery. Postoperative effective pain treatment provides early mobilization and shorter hospital stay.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Diseases, Breast Fibroadenoma
- Trial name
- NCT04297007
- Testing
- PECS block, Rhomboid intercostal block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Cardiac Surgery, Post-operative Pain
Reduce Nonsteroidal Antiinflammatory Drugs Doses for Analgesia After Sternotomy
Currently, the management of pain after cardiac surgery is based on the concept of multimodal analgesia: Combined use of non-opioid analgesics associated with morphine intravenous analgesia by a system controlled by the patient…
- Trial name
- LoDoNSAID (NCT02180087)
- Testing
- Ketoprofen
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
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