Clinical trials: Post-operative Wound Healing
Furcation Defects
Effect of Two Irrigation Protocols Applied Prior to Furcation Repair
Perforations are mishaps that might occur during the course of endodontic treatment mainly due to iatrogenic factors. However, they might also occur due to extensive decay of dentinal structure.
- Trial name
- NCT06757660
- Testing
- Furcation Repair
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Ischemia-Reperfusion Injury, Free Flap
Non-invasive Remote Ischemic PreConditioning (RIPC) in Free Flaps for Breast Reconstruction
This prospective randomized clinical study investigates the effects of Remote Ischemic Conditioning (RIC) on tissue perfusion and ischemia-reperfusion injury in patients undergoing free flap reconstruction in reconstructive…
- Conditions
- Ischemia-Reperfusion Injury, Free Flap, Conditioning Therapy
- Trial name
- RIPC (NCT07487220)
- Testing
- Remote ischemic preconditiong
- Where
- Germany
- Volunteers
- 49 people
- Sponsor
- Ruhr University of Bochum
Postoperative Pain
Factors Influencing Postoperative Pain After Gingival Graft Harvesting
This prospective cohort study aims to evaluate patient-related, psychological, and clinical factors influencing postoperative pain following gingival graft harvesting from the palate.
- Trial name
- NCT07377370
- Testing
- Gingival graft harvesting from the palate
- Where
- Spain
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Wound Healing and Prevention, Oral Inflammation
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation.
- Conditions
- Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management
- Trial name
- NCT07095556
- Testing
- Low-level laser therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Healing Surgical Wounds
Platelet Rich Fibrin in Soft Tissue Healing After Implant Uncovering
This study represents a prospective, controlled and randomized clinical trial assessing the effects of L-PRF on the healing time of the donor area and on the patient's postoperative morbidity in the 4 weeks following the Apically…
- Trial name
- NCT05375357
- Testing
- Application of L-PRF on the donor area, Secondary intention healing of the donor area
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Chronic Pain
Effect of Intraoperative Infiltration With Bupivacain on the Development of Chronic Pain After Inguinal Hernia Repair
The effect of intraoperative infiltration of the operation site with bupivacain on the development of chronic pain is the object of our trial.
- Trial name
- NCT00484731
- Testing
- Infiltration with Saline, Infiltration with Bupivacaine
- Where
- Switzerland
- Volunteers
- 404 people
- Sponsor
- Luzerner Kantonsspital
Post Operative Pain
Nalbuphine Plus Caudal Bupivacaine in Hypospadius Repair
Caudal aneasthesia for pediatric surgery was first reported in 1933. Since then, studies have described the indications for pediatric caudal block, the level of analgesia, doses, advantages and disadvantages of this technique.
- Trial name
- NCT03476772
- Testing
- Nalbuphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Gingival Recession
The Use of Cyanoacrylate on Palatal Wound
The palatal donor site of autogenous free gingival grafts significantly influences the patient's morbidity. The purpose of this study was to evaluate the efficacy of cyanoacrylate on palatal wound healing and postoperative…
- Trial name
- NCT03273010
- Testing
- Free gingival graft, Cyanoacrylate application
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ordu University
Ptosis, Blepharoptosis
Bandage Contact Lens in Post Operative Ptosis Patients
This study is being conducted to determine whether the use of bandage contact lens after ptosis surgery provides any benefits for the patient or is unnecessary.
- Trial name
- NCT03375879
- Testing
- Bandage contact lens
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Postoperative Morbidity, Trauma
Fruit And Vegetables and OUtcomes After Removal of Impacted TEeth
The proposed study will test the following hypotheses: 1. Pre-operative daily dual supplementation with Juice Plus+ (fruit \& vegetable) for 11 weeks will result in reduced post-operative morbidity in terms of quality of life…
- Conditions
- Postoperative Morbidity, Trauma, Wound Healing
- Trial name
- FAVOURITE (NCT01145820)
- Testing
- Juice plus
- Where
- United Kingdom
- Volunteers
- 246 people
- Sponsor
- University of Birmingham
Surgical Wound
Early Debridement Within 24 Hours After Surgery for Wound Healing of Abdominal Incision
Wound healing after surgery is a complex procedure. Liquefaction of the fat and necrosis of inactivated tissue, as well as blood clots are always accumulated mostly within 24 hours after surgery.
- Trial name
- NCT03798041
- Testing
- Debridement Within 24 Hours After Surgery
- Where
- China
- Volunteers
- 480 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Mitral Regurgitation, Computed Tomography
Atrial Fibrillation Risk After Miniinvasive Mitral Valve Repair
This retrospective cohort study investigates how CT-derived tissue quality parameters, serving as markers of metabolic status, predict post-operative atrial fibrillation risk in patients undergoing minimally invasive mitral valve…
- Conditions
- Mitral Regurgitation, Computed Tomography, Atrial Fibrillation
- Trial name
- NCT06707506
- Volunteers
- 114 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Free Gingival Graft
A-PRF and CGF in Palatal Donor Site Healing
The objective of this study was to compare and evaluate the effects of concentrated growth factor (CGF) and advanced platelet-rich fibrin (A-PRF) clot membranes on palatal epithelial wound healing and postoperative discomfort…
- Trial name
- FGG (NCT07439068)
- Testing
- Advanced platelet-rich fibrin, Concentrated growth factor, Sterile gelatin sponge
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ordu University
Post-operative Pain
Effectiveness of Continuous Femoral Nerve Block Versus Single Shot Femoral Nerve Block for Pain Control
Both single shot femoral nerve block and continuous femoral nerve block with catheter have been shown to be effective for pain control after anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT01916590
- Testing
- Bupivicaine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Colorado, Denver
Wound Heal, Postoperative Pain
Assessing the Efficacy of a Hydrogen Peroxide Gel for Oral Wound Healing and Oral Hygiene
This study aims to assess the effectiveness and safety of a hydrogen carbamide/peroxide gel, called UNISEPT® ORAL GEL, in promoting oral wound healing, alleviating postoperative symptoms, and enhancing oral hygiene.
- Conditions
- Wound Heal, Postoperative Pain, Biopsy Wound, Wound; Mouth
- Trial name
- NCT06370260
- Testing
- Hydrogen Carbamide/Peroxide Gel
- Where
- Greece
- Volunteers
- 54 people
- Sponsor
- National and Kapodistrian University of Athens
Inguinal Hernia
Peri-Operative Rehab Program for Inguinal Hernia Repair Surgery
Inguinal hernia repair is one of the most common surgeries, with more than 20 million performed globally each year. It is estimated that approximately 15% of patients undergoing inguinal hernia repair will experience persistent…
- Trial name
- NCT05069142
- Testing
- Rehabilitation
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of Alberta
Wound Healing
Efficacy of Early Postoperative ON101 Application for Lower-extremity Fracture Incisions: a Prospective Evaluator-blinded Controlled Study of Scar Quality and Digital-clinical Concordance
Background: Postoperative scars after lower-extremity fracture fixation endure high tension, where excessive scarring can restrict periarticular mobility.
- Trial name
- ON101 Efficacy (NCT07854470)
- Testing
- ON101
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- LIN Kai-Cheng
Cardiac Surgical Procedures, Wound Healing
Use of the Bra as Prevention of Sternal Wound Dehiscence in Cardiac Surgery
The aim of the study was to assess the efficacy of bra application as a prevention of dehiscence in women with median sternotomy.
- Trial name
- DEHISCENCIA (NCT04290260)
- Testing
- Use of breast bra, Usual care (not use of bra)
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Germans Trias i Pujol Hospital
Meniscus Disorder, Meniscus, Torn Tibial
Blood Flow Restriction After Meniscus Repair
The purpose of this study is to evaluate post-operative outcomes after meniscus surgery in participants undergoing blood flow restriction training as a rehabilitative adjunct compared to those with standard rehabilitation.
- Conditions
- Meniscus Disorder, Meniscus, Torn Tibial, Meniscus Lesion, Meniscus Tear, Tibial
- Trial name
- NCT04436523
- Testing
- Blood flow restriction (Delfi Personalized Tourniquet System), Standard rehabilitation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Local Analgesia Via Infiltration, Wound Heal
Comparison of Postoperative Effects of Articaine and Lidocaine in Mucogingival Surgery
The aim of this study is to compare and evaluate the effects of using lidocaine 2% (with adrenaline) and articaine 4% (with adrenaline) in free gingival graft (FGG) surgery on postoperative wound healing, changes in blood flow in…
- Conditions
- Local Analgesia Via Infiltration, Wound Heal, Pain, Postoperative, Hemorrhage
- Trial name
- NCT07145879
- Testing
- Lidocaine hydrochloride 2% with epinephrine 1:100 000, Articaine 4% with epinephrine 1:100,000, Free gingival graft (FGG)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pamukkale University