Clinical trials: Post-prandial Glucose Response
Hyperglycemia, Diabetes, and Obesity
Effects of Resistant Starch in a Beverage on Post-prandial Glycemic and Insulinemic Responses
Hypothesis: A beverage with a resistant starch will blunt and sustain the post-prandial rise in blood glucose and insulin concentrations compared to beverage with maltodextrin (an easily digested carbohydrate).
- Trial name
- NCT02161250
- Testing
- Resistant Starch, Control
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Gastric Emptying, Diabetes Mellitus
The Effect of Natural Food Flavourings on Gastrointestinal and Cardiovascular Physiological Responses.
The purpose of this study is to determine whether 3 g cinnamon was sufficient to delay the gastric emptying rate of a high-fat solid meal and subsequently reduce postprandial blood glucose and lipid responses, oxidative stress…
- Trial name
- CinnGastEmpt (NCT01350284)
- Testing
- Cinnamon
- Where
- Ireland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Glucose Intolerance, Glucose and Insulin Response
Sucralose and Glucose Metabolism in Young Healthy Adults
This study aimed to investigate the effects of a three-week consumption of sucralose-sweetened beverages (low-calorie sweetener) on postprandial glycemic responses in healthy adults, compared with sugar-sweetened beverages under…
- Conditions
- Glucose Intolerance, Glucose and Insulin Response, Glucose Homeostasis, Low-grade Inflammation
- Trial name
- NARELO (NCT07194772)
- Testing
- Low-calorie sweeteners (LCS), Refined sugars (SSB), Natural sugars (FJ)
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Blood Glucose Concentration, Glycemic Index
Non-alcoholic, Fiber-enriched Beer and Its Effect on Blood Glucose Concentration
This study examines how various non-alcoholic beverages affect blood sugar levels. The beverages are a non-alcoholic, fiber-enriched beer, a conventional non-alcoholic beer, and a sugar solution.
- Conditions
- Blood Glucose Concentration, Glycemic Index, Dietary Fiber, Non-alcoholic Beer
- Trial name
- NCT07131904
- Testing
- non-alcoholic, fiber-enriched beer (FEB), conventional, non-alcoholic beer, glucose solution
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- David Faeh
Type 1 Diabetes, Hyperglycemia, Postprandial
Glucagon Response to Prandial Insulin Administration in Persons With Type 1 Diabetes
Glucagon regulation and response in persons with T1D at the basal state and in response to various stimuli remains unclear. Dr. Philip Cryer has previously reported that, in T1D young adults with a course of the disease of 16+9…
- Trial name
- NCT04079881
- Testing
- Insulin
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Washington University School of Medicine
Post-prandial Glycaemic Response
Effect of Pea Flour in Bread on Blood Glucose
This study's overall goal is to investigate methods to improve the acceptability of pulse containing foods that provide a health benefit to consumers.
- Trial name
- NCT03506932
- Testing
- Untreated, Heat treated with 0% moisture, Heat treated with 10% moisture
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- St. Boniface Hospital
Post-prandial Glycemia
Effect of Mulberry Leaf Extract on Glucose Response of a Test Meal
The aim of this study is to test the effects of Mulberry leaf extract on glucose response of a standardized complete meal when taken just before or when mixed with the meal.
- Trial name
- NCT05112133
- Testing
- Mulberry leaf extract, Water
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Local Registration Trial in China Humalog Mix 50
The primary objective of this study is to compare the 2-hour PPBG excursion following a standard test meal in insulin-requiring diabetic patients treated twice daily with human insulin mix 50/50, versus the 2-hour PPBG excursion…
- Trial name
- NCT00191581
- Testing
- Humalog Mix 50, Human Insulin Mix 50:50
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus, Type 1
What is the Dose Response of Varying Meal Content of Fat on Postprandial Glycaemia in Children With T1DM?
Background: Based on international evidence, current management of people with T1DM on intensive insulin therapy (IIT) use algorithms based on the meal carbohydrate content (MCC) to calculate the prandial insulin dose.
- Trial name
- REQINSOIL (NCT02371694)
- Testing
- Test drink
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Cork University Hospital
Health, Subjective
Influence of Rapeseed Proteins on the Postprandial Metabolic Response
The aim of the study is to investigate the effect of rapeseed proteins on the postprandial metabolic response. Therefore, study participants will receive a meal rich in fat and carbohydrates with and without rapeseed protein or…
- Trial name
- NCT03620812
- Testing
- rapeseed or soy protein or no protein
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Healthy
Various Serving Sizes of Lentils on Blood Glucose and Insulin
The purpose of this study is to assess the effects of consuming either 1/2 or 1/4 cup servings of lentils on post-prandial blood glucose and insulin as compared to 4 types of starchy foods (corn, macaroni, white potato, white…
- Trial name
- NCT02940158
- Testing
- 1/4 cup- Small red lentil, 1/4 cup- Small green lentil, 1/4 cup- corn
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Type 1 Diabetes Mellitus, Adolescent
Effect of High Fat High Protein Meal in Type 1 Diabetes
Aim: Despite optimal glycemic control in individuals with type 1 diabetes, post-meal hyperglycemia remains a clinical challenge, and it has been identified as an independent risk factor for the development of long-term…
- Trial name
- T1DM-HFHP (NCT07158385)
- Testing
- Standard test meal (SM), High fat high protein meal-carbohydrate counting (HFHP), High fat high protein meal-fat counting (HFHP-a)
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people
- Sponsor
- Cumhuriyet University
Obesity, Diabetes
Comparison of Pulse Chips and Commercial Snacks on Food Intake, Appetite and Blood Glucose in Healthy Young Adults
Consumers are often forced to eat fast, convenient foods and snacks ("eat on the go") in order to match the pace of their lifestyles. However, these snack options more often than not offer little health benefit to the consumer.
- Trial name
- NCT03297931
- Testing
- Corn Chips + Onion Dip, Yellow pea chip + hummus, Pinto bean chip + hummus
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Prediabetes, Normal Plasma Glucose
The Effects of Nextida-GC and Whey Protein on Postprandial Glycemic and Insulinemic Responses When Given 30min Before, 10min Before or With a Standardized Breakfast Test-meal in Healthy Adults With and Without Prediabetes
The goals of this clinical trial are to learn if Nextida-GC (a peptide derived from collagen) will reduce postprandial glucose responses when taken 30 minutes before, 10 minutes before or with the first bite of a breakfast…
- Conditions
- Prediabetes, Normal Plasma Glucose, Normoglycemia
- Trial name
- NCT07174323
- Testing
- Peptide derived from collagen protein, Whey protein isolate
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- INQUIS Clinical Research
Glucose, High Blood, Inflammatory Response
Foodprint 1.0: Physiological Acute Responses After Consumption of Confectionary Products
The composition of a food or a meal consumed plays an important role in the rate of postprandial endocrine and metabolic response, especially if high in fats, sugars and total energy content and a reduction in its entity is…
- Conditions
- Glucose, High Blood, Inflammatory Response, Oxidative Stress, Endotoxemia
- Trial name
- FP1 (NCT03972878)
- Testing
- control snack, control cream, cream version 1
- Where
- Italy
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Parma
Obesity
Role of Colonic Short Chain Fatty Acids in Obesity
The excess production of colonic short-chain-fatty-acids (SCFA) has been implicated in the promotion of obesity, but colonic fermentation of dietary-fiber to SCFA may also play a role in preventing diabetes.
- Trial name
- NCT02562014
- Testing
- Glucose, Inulin, Resistant Starch
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy, Healthy Volunteer
Avocado and Postprandial Responses
The purpose of this study is to see how adding avocado to a breakfast meal affects blood sugar control and signals of hunger and fullness after eating.
- Conditions
- Healthy, Healthy Volunteer, Healthy Volunteers, Healthy Adult
- Trial name
- NCT06818032
- Testing
- Negative control, Avocado, Fat and fiber addition
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Vermont Medical Center
Type 1 Diabetes Mellitus, Glycemic Variability
Impact of Dietary Fat and Menstrual Cycle Phases in Type 1 Diabetes
This clinical trial aims to evaluate how variations in dietary fat content and hormonal status influence postprandial glycemic response in individuals with type 1 diabetes (T1D), with a special focus on women.
- Conditions
- Type 1 Diabetes Mellitus, Glycemic Variability, Sex Characteristics, Menstrual Cycle
- Trial name
- DIABETEXX/3 (NCT07278063)
- Testing
- Low Fat Mixed Meal, High Fat Mixed Meal
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Healthy
To Test the Effect of Selected Fibres and Flours in Flat Bread on Post-Prandial Blood Glucose and Insulin Responses in Healthy Indian Population
Double-blind, randomized, controlled, cross-over design with 3 test products and one control product. To evaluate the effect of 4 different flour compositions (guar gum 2% and 4%, chickpea flour 15% and barley flour 2% and 5%) of…
- Trial name
- NCT02814357
- Testing
- Control (market standard), wheat flour, chickpea flour
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Type 2 Diabetes Mellitus
Glycemic and Satiety Response Study of Fibre-Enriched Pudding Products
The purpose of this study is to determine the specific properties of a variety of dietary fibres that lead to different postprandial glycemic and satiety responses in individuals at risk for type 2 diabetes.
- Trial name
- Pudding (NCT02289612)
- Testing
- Yellow Mustard Gum Fibre, Soluble Flaxseed Gum Fibre, Fenugreek Gum Fibre
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Guelph