Clinical trials: Post-stroke Dysphagia
Stroke, Swallowing Disorders
Description and Modeling of Swallowing Disorders After a Stroke
The oropharyngeal junction participates in 3 interpenetrating functions: Swallowing, Breathing and Speech. In the context of ischemic or hemorrhagic stroke, these are altered, isolated or associated manner, causing major…
- Trial name
- AVC-MODE (NCT02974530)
- Testing
- Neurological evaluation, Laryngological evaluation, MRI evaluation
- Where
- 4 sites in France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Stroke
The Changes of Masticatory / Swallowing Functions and Oropharyngeal Muscle Mass on Sonography After Comprehensive Swallowing Training and Tongue - Pressure Resistance Training in Stroke Patients With Dysphagia
The aims of this study are: 1. Comparing the ultrasound imaging performance of swallowing and chewing function, tongue pressure and oropharyngeal muscle thickness in stroke patients with different levels of swallowing function 2.
- Trial name
- NCT06269718
- Testing
- swallowing therapy, IOPI therapy
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Acute Stroke, Dysphagia
Improving SWAllowing After Stroke With Transcranial Direct Current Stimulation
In the acute phase of stroke, dysphagia (difficulty/inability to swallow) is a common problem that can have serious consequences such as aspiration pneumonia, increased lenght of hospitalisation, and death.
- Trial name
- iSWAT (NCT01758991)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Dysphagia, Stroke
Fostering Eating After Stroke With Transcranial Direct Current Stimulation
Swallowing difficulties are common after a stroke and can lead to serious complications like pneumonia and malnutrition. Unfortunately, there are no effective treatment for improving swallowing in stroke patients.
- Trial name
- FEASt (NCT01919112)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Dysphagia After Stroke, Cortical Swallowing Network
To Explore the Functional Connectivity Pattern of Cortical Swallowing Network in the Oral Phase of Post-stroke Dysphagia Based on Dynamic Causal Modelling
Swallowing activity in the oral phase is regulated by the cortical swallowing network, and the functional connectivity pattern of the cortical swallowing network is related to swallowing activity.
- Conditions
- Dysphagia After Stroke, Cortical Swallowing Network, Functional Magnetic Resonance Imaging, Oral Phase
- Trial name
- NCT06564688
- Testing
- Swallowing function test
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Fujian University of Traditional Chinese Medicine
Stroke, Dysphagia
The Relative Effectiveness of BOLUS Versus Continuous Nasogastric Feeding After Stroke: a Proof of Principal Study
Patients with severe strokes are often unable to be take oral diet food and fluids safely because they cannot swallow effectively.
- Trial name
- BOLUS (NCT04011787)
- Testing
- bolus NGT feeding, Continuous NGT feeding, Continuous Glucose Monitoring
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals of North Midlands NHS Trust
Dysphagia
Tongue Pressure Profile Training for Dysphagia Post Stroke
People with swallowing impairment experience particular difficulty swallowing thin liquids safely; the fast flow of liquids makes them difficult to control.
- Trial name
- TPPT (NCT01370083)
- Testing
- Tongue Pressure Profile Training, Tongue-Pressure Strength-and-Accuracy Training
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Toronto Rehabilitation Institute
Stroke
Changes of Swallowing Function and Oropharyngeal Muscle Mass on Sonography After Comprehensive Swallowing Therapy and Neuromuscular Electrical Stimulation in Stroke Patients With Dysphagia
1. The inter-rater and intra-rater reliability of sonography. 2. To explore that sonography is a clinically practical tool for assessing the changes of oropharyngeal muscles mass. 3.
- Trial name
- NCT04728737
- Testing
- swallowing therapy, IOPI therapy, neuromuscular electrical stimulation (NMES) therapy
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Oropharyngeal Dysphagia, Stroke
The Utility of Cerebellar Transcranial Magnetic Stimulation in the Neurorehabilitation of Dysphagia After Stroke
The study is designed to explore the effectiveness of non-invasive cerebellar stimulation to enhance motor plasticity in the cortex after stroke.
- Trial name
- NCT03274947
- Testing
- Cerebellar TMS
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Dysphagia, Videofluoroscopy
Dysphagia After Different Swallowing Therapies
Dysphagia after stroke is associated to increased pulmonary complications and mortality. The swallowing therapies could decrease the pulmonary complications and improve the quality of life after stroke.
- Conditions
- Dysphagia, Videofluoroscopy, Stroke
- Trial name
- NCT03048916
- Testing
- general swallowing therapy, NMES therapy
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Dysphagia
Mechanisms of Air-pulse Pharyngeal Sensory Stimulation Regulation Post-stroke Swallowing Neural Network Remodeling Via TRPV4 Channel
This randomized, double-blind, sham-controlled clinical trial will investigate the effects and potential neural mechanisms of pharyngeal air-pulse sensory stimulation in patients with post-stroke dysphagia.
- Trial name
- NCT07782424
- Testing
- Air-Pulse Sensory Stimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Foshan