Clinical trials: Post-stroke Upper Limb Hemiparesis
Stroke, Stroke Acute
Research on the Effectiveness of Neurorehabilitation After Stroke
This clinical trial aims to investigate the effectiveness of a novel neurorehabilitation technology for treating stroke in adults.
- Conditions
- Stroke, Stroke Acute, Stroke with Hemiparesis, Stroke, Acute
- Trial name
- NCT06753006
- Testing
- Neurorehabilitation simulator, Standard course
- Where
- Russia
- Volunteers
- 44 people
- Sponsor
- Neurotechnika
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Hemiparesis
Robotic Brace Incorporating Electromyography for Moderate Affected Arm Impairment After Stroke
Of the 5.7 million stroke survivors in the United States, up to 80% exhibit significant weakness in one arm (called "hemiparesis"). This devastating impairment undermines performance of valued activities and quality of life.
- Trial name
- NCT01654315
- Testing
- Myomo Robotic Arm, RTP Standard Therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Ohio State University
Stroke, Hemiparesis
Motor Learning for Upper Limb Hemiparesis After Stroke
The purpose of this research is to learn about practice conditions that may benefit stroke survivors when learning to use their more affected arm to perform a task. Participants will be randomized into two groups.
- Trial name
- NCT05765474
- Testing
- Practice Variable, No Practice Variable
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Columbia University
Stroke (CVA) or TIA, Hemiparesis
Mirror Therapy on Motor Recovery and Pain of Hemiparetic Arm
evaluate the effect of mirror therapy on motor recovery and pain of hemiparetic arm post stroke
- Trial name
- NCT07358169
- Testing
- technique, Control
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Stroke, Cerebrovascular Accident (CVA)
Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke
The purpose of this study is to evaluate if multiple therapy sessions of Transcutaneous Vagus Nerve Stimulation (tVNS) combined with robotic arm therapy lead to a greater functional recovery in upper limb mobility after stroke…
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Hemiparesis
- Trial name
- tVNS (NCT03592745)
- Testing
- Transcutaneous Vagus Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Northwell Health
Hemiparesis
A Music-based VR Intervention for Upper Limb Motor Rehabilitation in Hemiparetic Patients
Hemiparesis affects the majority of stroke patients in the acute phase. In post-stroke motor rehabilitation patients can re-learn motor sequences through repetitive training.
- Trial name
- NCT04977609
- Testing
- VR+MUSIC, VR, TAU
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Catholic University of the Sacred Heart
Stroke, Upper Limb Motor Impairment
tDCS Combined With Constraint-Induced Therapy in Post-Stroke Upper Limb Rehabilitation
The objective of this clinical trial is to evaluate the effects of transcranial direct current stimulation (tDCS) combined with constraint-induced therapy (CIT) on upper limb motor recovery in individuals after stroke.
- Conditions
- Stroke, Upper Limb Motor Impairment, Post-Stroke Hemiparesis
- Trial name
- tDCS-CIT Strok (NCT07458503)
- Testing
- transcranial direct current stimulation (tDCS), Constraint-induced movement therapy
- Where
- 2 sites in Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade do Estado do Pará
Stroke
Transcranial Galvanic Stimulation After Stroke
Transcranial galvanic stimulation (tDCS) seems to promote motor recovery after stroke by stimulating (anodal) or inhibiting (cathodal) neural circuits in the brain.
- Trial name
- TraGAT (NCT00407667)
- Testing
- transcranial galvanic stimulation
- Where
- 3 sites in Germany, Italy
- Volunteers
- 96 people
- Sponsor
- Charite University, Berlin, Germany
Stroke
Robotic Rehabilitation of the Upper Limb After a Stroke
Hemiparesis is the most common motor disorder after a stroke. Most patients do not recover functional use of their paretic upper limb.
- Trial name
- ROBOASSIST (NCT03584477)
- Testing
- Robot InMotion 2.0, Conventional rehabilitation
- Where
- 2 sites in France
- Volunteers
- 54 people
- Sponsor
- Clinique Les Trois Soleils
Stroke, Post-Stroke Spasticity
ESTIM-UL: FES for Upper Limb Recovery After Stroke
Stroke is a leading cause of long-term disability, frequently resulting in impaired upper limb motor function and spasticity. Although Botulinum Toxin Type A (BoNT-A) is effective in reducing focal spasticity, functional recovery…
- Conditions
- Stroke, Post-Stroke Spasticity, Post-Stroke Hemiparesis
- Trial name
- ESTIM-UL (NCT07513714)
- Testing
- Functional Electrical Stimulation (FES), Conventional Rehabilitation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Foggia
Stroke
"Reliability of Motricity Index Strength Assessments for Upper Extremity in Post Stroke Hemiparesis- a Correlation Study''
Initially, a written consent was obtained from each participant. Then they became familiar with the procedure. For intrarater reliability, the first rater assessed the strength of pinch grip, elbow flexion and shoulder abduction…
- Trial name
- NCT02353520
- Testing
- motricity index strength assessment
- Volunteers
- 20 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Hemiplegia and/or Hemiparesis Following Stroke
Upper Extremity Robotic Rehabilitation in Patients With Hemiplegia
Comparison of Upper Extremity Robotic Rehabilitation Efficiency with Conventional Rehabilitation in Patients with Hemiplegia after Cerebrovascular Event
- Trial name
- NCT04393480
- Testing
- Robotic therapy, Conventional therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Sahel Taravati, M.D.
Cerebrovascular Accident
Use of a Mechanically Passive Rehabilitation Device in Vietnam: Impact on Upper Extremity Hemiparesis After Stroke
The goal of this project is to test a device (Zondervan et al, 2013) that can provide active assistance for arm training for people in Vietnam with severe to moderate stroke, but that is also simple and does not rely on powered…
- Trial name
- NCT02327767
- Testing
- Resonating Arm Exerciser
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- California State University, Northridge
Upper Extremity Weakness, Stroke
A Study to Evaluate Lower Extremity Sleeve and Pump Device to Treat Hemiparesis
The primary purpose of this study is to establish that application of a Sequential Compression Device (SCD) and lower extremity (LE) sleeve applied to a hemi-paretic upper extremity is safe.
- Trial name
- NCT05535257
- Testing
- Sequential Compression Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Stroke, Cerebrovascular Disorders
Dose Optimization for Stroke Evaluation
This study is about rehabilitation of arm function after a stroke. The investigators are testing the dosage of therapy that is needed for meaningful recovery of arm and hand function.
- Conditions
- Stroke, Cerebrovascular Disorders, Brain Ischemia, Infarction
- Trial name
- DOSE (NCT01749358)
- Testing
- Accelerated Skill Acquisition Program (ASAP), Active Monitoring
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Southern California
Stroke
Telerehabilitation for Post-Stroke Hand Function
This pilot randomized controlled trial will evaluate the feasibility and preliminary effects of a home-based, technology-enabled hand telerehabilitation program for adults with chronic stroke.
- Trial name
- NCT07792655
- Testing
- Technology-Supported Hand Training, Pamphlet-Supported Hand Activity
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Cerebrovascular Accident
Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis
The results of this study will provide sound, scientific evidence of physiologic mechanisms responsible for upper-extremity weakness; evidence of the processes involved in neuromuscular adaptation; and will elucidate the…
- Trial name
- NCT00125658
- Testing
- Control, Experimental
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke
Study of Neurophysiological Markers of Motor Recovery in Post-stroke Patients.
The aim of the study was to explore potential pathways for recovery and adaptation of neural pathways after stroke by examining electrical activity of the brain cortex and cortico-spinal excitability using transcranial magnetic…
- Trial name
- NCT06386627
- Testing
- Stimulus response task, Transcranial magnetic stimulation
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Stroke, Hemiparesis
Proprioceptive Stimulation With Manual Bilateral Rhythmic Exercise in Post-stroke Patients
The purpose of this study is to evaluate the effect of the repetitive proprioceptive bilateral stimulation for the early recovery of the voluntary muscle contraction in stroke patients.
- Trial name
- BAT (NCT03155399)
- Testing
- Proprioceptive based training (PBT), Conventional neuromotor treatment (CNT).
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy