Clinical trials: Post-stroke Upper Limb Hemiparesis
Stroke, Hemiparesis
The Effects of Mirror-Based Virtual Reality Systems and Recalibration Software on Upper Extremity Function in Individuals Experiencing Hemiparesis Post-Stroke
The goal of this study is to learn about the benefits of using a virtual reality gaming system that can be adjusted for a person who has upper arm weakness from stroke.
- Trial name
- NCT05856669
- Testing
- Virtual reality gaming
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Alabama at Birmingham
Stroke, Post-Stroke Hemiparesis
Evaluation of a Wearable Exoskeleton for Functional Arm Training
The purpose of this study is to investigate how the cable-driven arm exoskeleton (CAREX) can assist task performance during 3D arm movement tasks under various experimental conditions in healthy individuals and patients with…
- Trial name
- NCT02726204
- Testing
- Gravity Elimination Alone, Path Assistance Alone, Path Assistance and Gravity Elimination
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Stroke, Hemiparesis
Constraint-Induced Movement Therapy (CIMT) with Motor Relearning Program (MRP) and Bobath Approach to Augment Functional Motor Recovery of Chronic Hemiparetic Arm
Hemiparesis is a condition characterized by weakness or the inability to move on one side of the body, making it difficult to perform everyday activities like eating or dressing (Iswatun et al., 2022).
- Conditions
- Stroke, Hemiparesis, Hemiparesis After Stroke, Motor Function
- Trial name
- CIMT-MRP (NCT06806553)
- Testing
- Constraint-Induced Movement Therapy (CIMT) With Motor Relearning Program (MRP), Bobath Therapy
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- University of Lahore
Stroke, Hemiparesis
Motor Learning for Upper Limb Hemiparesis After Stroke
The purpose of this research is to learn about practice conditions that may benefit stroke survivors when learning to use their more affected arm to perform a task. Participants will be randomized into two groups.
- Trial name
- NCT05765474
- Testing
- Practice Variable, No Practice Variable
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Columbia University
Stroke, Hemiplegia
Brain Stimulation and Rehabilitation for Adults With Chronic, Severe Arm Motor Impairment After Stroke
This pilot study will examine a combination therapy for adults with chronic, severe motor impairment of an arm after stroke. The intervention will combine brain stimulation with physical rehabilitation of the arm on the side of…
- Conditions
- Stroke, Hemiplegia, Hemiparesis
- Trial name
- NCT03538795
- Testing
- iTBS&eCIMT
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Alabama at Birmingham
Stroke, Hemiparesis
IpsiHand System for Rehabilitation of the Arm and Hand After Stroke
This study aims to assess whether the NeuroLutions Upper Extremity Rehabilitation System (known as IpsiHand) will help stroke patients regain strength and functional movements in their arm.
- Trial name
- NCT04123808
- Testing
- IpsiHand Treatment
- Sponsor
- Columbia University
Stroke, Brain Infarction
Arm Rehabilitation Study After Stroke
This study is about arm and hand recovery after a stroke. The investigators are testing an experimental arm therapy called Accelerated Skill Acquisition Program (ASAP) which combines challenging, intensive and meaningful practice…
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- ICARE (NCT00871715)
- Testing
- Accelerated Skill Acquisition Program (ASAP), Dose-Equivalent Usual & Customary Care - DEUCC, Usual and Customary Care - UCC
- Where
- 8 sites in United States
- Volunteers
- 361 people
- Sponsor
- University of Southern California
Ischemic Stroke, Upper Extremity Hemiparesis
Stroke Wearable Operative Rehabilitation Device Impact Trial
The objective of this study is to determine the impact of vibratory feedback on the quality and intensity of a common motor rehabilitation task of the upper-arm (hand-to-mouth) in stroke patients.
- Trial name
- SWORD-IT (NCT01967290)
- Testing
- Vibratory feedback and 3D movement analysis, Only 3D movement analysis
- Where
- 3 sites in Portugal
- Volunteers
- 44 people
- Sponsor
- Centro Hospitalar de Entre o Douro e Vouga
Cerebrovascular Accident
Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis
The results of this study will provide sound, scientific evidence of physiologic mechanisms responsible for upper-extremity weakness; evidence of the processes involved in neuromuscular adaptation; and will elucidate the…
- Trial name
- NCT00125658
- Testing
- Control, Experimental
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke, Hemiparesis
EEG Brain-Machine Interface Control of an Upper-Limb Robotic Exoskeleton for Robot-Assisted Rehabilitation After Stroke
The goal of this study is to develop a clinically feasible, low-cost, nonsurgical neurorobotic system for restoring function to motor-impaired stroke survivors that can be used at the clinic or at home.
- Trial name
- NeuroExo (NCT05374486)
- Testing
- NeuroExo co-robot neurorehabilitation system
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Houston
Stroke, Hemiparesis
Study of the Recovery of Muscle Function in the Arm/Hand After a Stroke
The purpose of this study is to examine if practicing joint movements using specially designed devices can help in the recovery of muscle function in the arm/hand after a stroke.
- Trial name
- NCT01422005
- Testing
- Simultaneous Bimanual training, Conventional Occupational Therapy
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- NYU Langone Health
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Stroke
Combining Robotic-Assisted Therapy and Pharmacotherapy in Post-Stroke Rehabilitation
Stroke is the leading cause of acquired long-term disability in adults in developed countries. Despite aggressive rehabilitation, lasting upper extremity impairment remains in the majority of stroke survivors.
- Trial name
- NCT02346630
- Testing
- Levodopa / Carbidopa, Armeo
- Where
- United States
- Sponsor
- Ross D. Zafonte, MD
Cerebrovascular Accident
Use of a Mechanically Passive Rehabilitation Device in Vietnam: Impact on Upper Extremity Hemiparesis After Stroke
The goal of this project is to test a device (Zondervan et al, 2013) that can provide active assistance for arm training for people in Vietnam with severe to moderate stroke, but that is also simple and does not rely on powered…
- Trial name
- NCT02327767
- Testing
- Resonating Arm Exerciser
- Where
- Vietnam
- Volunteers
- 30 people
- Sponsor
- California State University, Northridge
Upper Extremity Weakness, Stroke
A Study to Evaluate Lower Extremity Sleeve and Pump Device to Treat Hemiparesis
The primary purpose of this study is to establish that application of a Sequential Compression Device (SCD) and lower extremity (LE) sleeve applied to a hemi-paretic upper extremity is safe.
- Trial name
- NCT05535257
- Testing
- Sequential Compression Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Post-stroke Hemiparetic Patients (at Least 6 Months Post Stroke), Age Between 18-75 Years
Evaluation of the Effects of Rehabilitation Using the "Wii" on Upper Limb Kinematics in Chronic Stroke Patients.
The purpose of this study is to evaluate changes in strategies of hemiparetic upper limb movement in chronic stroke patients following rehabilitation using the "Nintendo Wii".
- Trial name
- WII (NCT01806883)
- Testing
- WII Rehabilitation, Traditional rehabilitation
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Spinal Cord Injuries and Disorders
Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis
This study plans to use systems that have been developed by Medtronic to investigate the use of cervical spinal cord stimulation to treat adults with upper limb hemiparesis resulting from a stroke.
- Conditions
- Stroke, Spinal Cord Injuries and Disorders, Hemiparesis After Stroke
- Trial name
- NCT07153536
- Testing
- Spinal Cord Stimulator (Medtronic Inceptiv™ System), Physical Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Marco Capogrosso
Stroke, Hemiplegia
Effects of Intermitted Theta Burst Stimulation (iTBS) on Motor Recovery of Upper Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of upper…
- Conditions
- Stroke, Hemiplegia, Hemiparesis After Stroke, Hand Functionality
- Trial name
- NIMBLE (NCT07073248)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Danderyd Hospital
Stroke, Hemiparesis of the Upper Limb Following Stroke
Repetitive Action Simulation Circuit Training to Reduce Arm Weakness After a Stroke
This study aims to examine the effect of an action simulation circuit training for individuals who have experienced upper extremity weakness following a stroke.
- Trial name
- NCT07772284
- Testing
- Upper Extremity Action Simulation Circuit Training
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Towson University
Stroke
Telerehabilitation for Post-Stroke Hand Function
This pilot randomized controlled trial will evaluate the feasibility and preliminary effects of a home-based, technology-enabled hand telerehabilitation program for adults with chronic stroke.
- Trial name
- NCT07792655
- Testing
- Technology-Supported Hand Training, Pamphlet-Supported Hand Activity
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan