Clinical trials: Post-surgical Wound Healing
Corneal Dystrophy, Epithelial Basement Membrane, Epithelial Recurrent Erosion Dystrophy
Cacicol20® in Corneal Wound Healing and Nerve Regeneration After Phototherapeutic Keratectomy
The objective of this clinical study is to test the efficacy of CACICOL20® (RGTA OTR 4120) in improving wound healing and nerve regeneration in the anterior cornea, in a patient population undergoing therapeutic laser treatment…
- Conditions
- Corneal Dystrophy, Epithelial Basement Membrane, Epithelial Recurrent Erosion Dystrophy, Corneal Erosions
- Trial name
- CACICOL-PTK (NCT02373397)
- Testing
- Cacicol20
- Where
- 2 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Neil Lagali
Surgical Site Infection (SSI), Mediastinitis
Use of Platelet-Rich Plasma to Reduce Sternal Wound Complications After CABG With Median Sternotomy
The goal of this clinical trial is to learn whether applying autologous platelet-rich plasma (PRP) to the sternal wound during heart surgery improves wound healing and reduces complications after surgery.
- Conditions
- Surgical Site Infection (SSI), Mediastinitis, Delayed Wound Healing
- Trial name
- NCT07352020
- Testing
- Autologous Platelet-Rich Plasma (PRP) Application, Standard Sternal Wound Closure
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Atrial Fibrillation
Vitamin C for Prophylaxis of Post-operative Atrial Fibrillation in On-pump Cardiac Surgery Procedures
The purpose of this study is to determine whether vitamin C is effective in the prophylaxis of post-operative atrial fibrillation in on-pump cardiac surgery
- Trial name
- NCT01107730
- Testing
- Vitamin C, L-Carnitine
- Where
- Greece
- Volunteers
- 33 people
- Sponsor
- Attikon Hospital
Soft Tissue Support and Repair
The SeriScaffold® Use in Reconstruction Post Market Study for Tissue Support and Repair in Breast Reconstruction Surgery in Europe
This is a post-market study of the use of SeriScaffold® for soft tissue support and repair in breast reconstruction surgery.
- Trial name
- NCT01389232
- Testing
- SeriScaffold® Surgical Scaffold
- Where
- 5 sites in Germany, Italy and 2 more
- Volunteers
- 104 people
- Sponsor
- Sofregen Medical, Inc.
Surgical Site Infection, Wound Heal
The Efficacy of Purse-string Skin Closure With Negative Pressure Wound Therapy (NPWT) After Ileostomy Reversal
Evaluating the effectiveness of the existing 'linear suture + wound drain placement' and 'purse-string suture + negative pressure wound therapy' through a prospective comparative study
- Trial name
- NCT04986111
- Testing
- Linear skin closure with wound drain, Purse-string skin closure with negative pressure wound therapy
- Where
- South Korea
- Volunteers
- 138 people
- Sponsor
- Seoul National University Bundang Hospital
Gastroschisis
Music Therapy: An Adjunct To Gastroschisis Infants' Care
The investigators hope to determine if music therapy will have beneficial effects on physiologic parameters, behavioral states, and pain scale evaluations in infants with gastroschisis defects and if music therapy promotes…
- Trial name
- MAGIC (NCT01469208)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Wounds and Injuries
Study to Evaluate Polyheal-1 in Treatment of Recalcitrant Wounds
The objective of this study is to evaluate the performance of Polyheal-1 compared to Saline in the treatment of recalcitrant wounds including venous, post-operative and post-traumatic chronic wounds with different etiologies…
- Trial name
- NCT00552643
- Testing
- Suspension of polystyrene beads (POLYHEAL 1), Saline (0.9% NaCl)
- Where
- 6 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Polyheal Ltd.
Edentulous Alveolar Ridge, Dental Trauma
Dimensional Changes of the Labial Alveolar Ridge After Socket Shield Technique With Computer Guided Root Sectioning
In this study, the dimensional changes of the labial alveolar ridge are digitally assessed after immediate implant placement using the socket shield technique with computer guided sectioning of the root.
- Trial name
- NCT05366985
- Testing
- Socket shield technique with computer guided sectioning of the root
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Otitis Media Chronic, Temporal Bone
Efficacy of Platelet- and Extracellular Vesicle-rich Plasma in Chronic Postsurgical Temporal Bone Inflammations
This clinical study evaluates the efficacy of the autologous blood-derived product called platelet- and extracellular vesicle-rich plasma (PVRP) for the treatment of chronically inflamed post-surgical temporal bone cavities.
- Trial name
- PvRP-ear (NCT04281901)
- Testing
- Platelet- and extracellular vesicle-rich plasma, Standard conservative treatment
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- University Medical Centre Ljubljana
Carotid Endarterectomy
Blood Flow Evaluation After Carotid Surgical Treatment
Approximately 20% of strokes originate from the rupture of an atherosclerotic plaque in the carotid artery. Surgical revascularization, i.e.
- Trial name
- BEAT (NCT06827509)
- Testing
- Ultrasound-based flow imaging
- Volunteers
- 40 people
- Sponsor
- Rijnstate Hospital
Wound Healing, Abdominal Surgery
Management of Abdominal Post-surgical Scar With Ozoaqua Versus Standard Care
A prospective, randomized clinical study with a blinded evaluator to compare a post-surgical abdominal scar care protocol using Ozoaqua products versus standard care in patients undergoing open abdominal surgery.
- Conditions
- Wound Healing, Abdominal Surgery, Scar Improvement
- Trial name
- NCT07678372
- Testing
- Ozonated product-based protocol for scar hygiene and care
- Where
- 2 sites in Spain
- Volunteers
- 144 people
- Sponsor
- Laboratorios Ozoaqua
Hernia, Ventral, Body Image
Functional Outcome After Incisional Hernia Repair: Open Versus Laparoscopic Repair
Background: Midline incisional hernia is reported from 0,5 to 11% after abdominal operations. Primary repair without mesh reinforcement is almost abandoned because of high recurrence rates (24 to 46%).
- Conditions
- Hernia, Ventral, Body Image, Respiratory Function Tests, Quality of Life
- Trial name
- GINCISHERNIA (NCT00625053)
- Testing
- Laparoscopic repair, Open midline incisional hernia repair
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Geneva
External Oblique Intercostal Fascial Plane Block, Rectus Sheath Block
External Oblique Intercostal Fascial Plane Block Versus Rectus Sheath Block for Postoperative Analgesia
This study aimed to compare the analgesic efficacy of the external oblique intercostal fascial plane block (EOIPB) versus the rectus sheath block (RSB) for managing postoperative pain following paraumbilical hernioplasty.
- Conditions
- External Oblique Intercostal Fascial Plane Block, Rectus Sheath Block, Pain
- Trial name
- NCT07601945
- Testing
- External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Helwan University
Apical Periodontitis, Endodontically Treated Teeth
Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery
The purpose of this study is to evaluate the effect of Photobiomodulation (PBM) in postoperative pain after endodontic microsurgery (EMS) in patients from the University of Texas Health Science Center at Houston, School of…
- Conditions
- Apical Periodontitis, Endodontically Treated Teeth, Endodontic Disease, Apical Cyst
- Trial name
- NCT06574152
- Testing
- PBM treatment, EMS
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- The University of Texas Health Science Center, Houston
Chronic Inflammatory Gingival Enlargement, Gingival Enlargement
Wound Healing After Gingivectomy
Gingival enlargement caused by chronic inflammation may require surgical intervention when non-surgical periodontal therapy is insufficient.
- Conditions
- Chronic Inflammatory Gingival Enlargement, Gingival Enlargement, Gingival Hyperplasia
- Trial name
- OZONE-GING (NCT07517328)
- Testing
- Gaseous ozone application, Gingivectomy/gingivoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ataturk University
Surgical Wound, Healed, Post Operative Pain
Impact of Advanced Platelet Rich Fibrin and Enamel Matrix Derivative on Clinical and Molecular Wound Healing Parameters After Surgical Removal of Mandibular Third Molars
Brief summary The goal of this study is to compare the effects of advanced platelet rich fibrin and enamel matrix derivative placed in the extraction alveoli of patients who had surgical removal of mandibular wisdom teeth.
- Trial name
- NCT06190015
- Testing
- Advanced platelet rich fibrin (APRF) clots, Enamel matrix derivative (EMD) group
- Where
- Serbia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Tooth, Impacted
Piezoelectric Vibrations and Tissue, Cellular and Molecular Mechanisms of Oral Wound Healing After Third Molar Surgery
The aim of this clinical trial is to investigate and compare the effect of piezoelectric surgery on tissue, cellular and molecular level of oral surgical wound healing and postoperative outcomes (pain, swelling, trismus) after…
- Trial name
- NCT02942108
- Testing
- piezo surgery, conventional surgery
- Where
- Serbia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Supraspinatus Tear
Does Autologous Conditioned Plasma Enhance Rotator Cuff Tendon Healing After Surgery?
The aim of this study is to establish if the application of autologous conditioned plasma (ACP), also described as platelet rich plasma (PRP), to the site of supraspinatus tendon repair beginning within two weeks of surgery, can…
- Trial name
- NCT01414764
- Testing
- Autologous conditioned plasma (ACP)
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- The University of Western Australia
Diabetic Foot, Postoperative Wound Healing
OEOd-Based Wound Dressing in Post-Surgical Diabetic Foot Ulcers
This study is a prospective randomized controlled pilot study evaluating the efficacy and safety of an OEOd-based wound dressing compared with standard wound care in patients with post-surgical diabetic foot ulcers.
- Trial name
- OEOd-DFU-pilot (NCT07368816)
- Testing
- OEOd-based wound dressing, Standard of Care (Investigator Choice)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Ospedale San Donato
Heart Valve Diseases, Mitral Valve Insufficiency
Normal Values in Stress Echocardiographic Parameters in Patients After Successful Mitral Valve Repair for Organic MR
Surgical treatment is the only approach with potentially defined clinical success for organic mitral valve (MV) regurgitation. Recurrent or persistent complaints after initial successful MV repair is a clinical challenge in…
- Conditions
- Heart Valve Diseases, Mitral Valve Insufficiency, Heart; Dysfunction Postoperative, Cardiac Surgery, Heart; Disease, Mitral(Valve)
- Trial name
- SEP (NCT02371863)
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- UMC Utrecht