Clinical trials: Post-surgical Wound Healing
Rotator Cuff Tears
Hydrotherapy Versus Classical Rehabilitation After Surgical Rotator Cuff Repair
Postoperative rehabilitation following rotator cuff repair is important to promote tendon healing, restore strength, and recover normal function.
- Trial name
- NCT05106842
- Testing
- Hydrotherapy, Land-based Therapy
- Where
- Switzerland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- La Tour Hospital
Decubitus Ulcer
Case Series Assessing TissuGlu® Surgical Adhesive in Flap Surgery for Decubitus Repair
To evaluate the impact of a high strength lysine-based adhesive (TissuGlu® Surgical Adhesive) on complications and revision rates in large flap surgery for decubitus repair.
- Trial name
- NCT03482999
- Testing
- TissuGlu Surgical Adhesive
- Volunteers
- 50 people
- Sponsor
- Cohera Medical, Inc.
Impacted Mandibular Third Molar
Does Vitamin C Improve Postoperative Healing
This randomized, split-mouth clinical trial investigates the effect of oral vitamin C supplementation on postoperative recovery following the surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07012564
- Testing
- Vitamin C
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Wound Healing
Cell Suspension With Biologic Dressing for Burn Wounds
This study is a prospective, multicenter, real-world observational study. It aims to evaluate the effectiveness and safety of a combined therapy-autologous epidermal cell suspension followed by biological dressing (porcine…
- Trial name
- NCT07555418
- Testing
- Autologous Epidermal Cell Suspension
- Volunteers
- 386 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Laceration of Skin
Evaluation of Zip Device to Conventional Sutures for Laceration Repair in Pediatrics in an Emergency Department
A prospective, randomized, controlled post-market clinical investigation that will enroll pediatric subjects requiring laceration repair.
- Trial name
- ZIPPED (NCT04122859)
- Testing
- Zip Skin Closure Device
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- ZipLine Medical Inc.
Palatal Donor Site Wound Healing, Periodontal Plastic Surgery
MOUTHRİNSES AND PALATAL DONOR SİTE HEALİNG AFTER FREE GİNGİVAL GRAFT
This single-blind randomized controlled clinical trial aimed to compare the effects of hypochlorous acid, hyaluronic acid, and chlorhexidine mouthrinses on palatal donor site healing following free gingival graft surgery.
- Trial name
- NCT07689695
- Testing
- Hypochlorous Acid, Hyaluronic Acid (HA), Chlorhexidine gluconate 0.2%
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Yuzuncu Yil University
Inguinal Hernia Repair, Post Operative Pain
Nitrous Oxide On Acute Postoperative Pain and Opioid Consumption and Chronic Pain After Inguinal Hernia Repair Surgery
To compare postoperative pain, opioid consumption and chronic pain in patients undergoing to hernia repair surgery after receiving nitrous oxide or oxygen during the general anesthesia.
- Trial name
- NCT01622322
- Testing
- Nitrous Oxide, oxygen
- Where
- Turkey (Türkiye)
- Sponsor
- The Cleveland Clinic
Inguinal Hernia Unilateral, Postoperative Pain Management
Transversalis Fascia Plane Block Versus Surgical Wound Infiltration for Postoperative Analgesia in Open Inguinal Hernia Repair
The purpose of this clinical trial is to evaluate whether two different analgesic techniques - ultrasound-guided Transversalis Fascia Plane Block (TFPB) and surgical wound infiltration - can improve postoperative pain control in…
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain Management, Regional Anaesthesia, Transversalis Fascia Plane Block
- Trial name
- TFPB-WIN (NCT07238829)
- Testing
- Ultrasound-Guided Transversalis Fascia Plane Block (TFPB), Surgical Wound Infiltration
- Volunteers
- 104 people
- Sponsor
- Ondokuz Mayıs University
Postoperative Complications
Effect of Probiotics on Pain and Oral Wound Healing After Third Molar Surgery
The aim of this research is to study the effect of probiotic supplements (Lactobacillus reuteri) on post-surgical complications and oral wound healing after extraction of impacted third molars.
- Trial name
- PROVIS (NCT02572531)
- Testing
- L. reuteri DSM 17938/ATCC PTA
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Wound Surgical, Wound Heal
Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part I
The purpose of the present study is to observe and compare -through a biomolecular analysis- the differences in the gene expression and cellular behavior in the early wound healing process -24 hours after injury- between the…
- Conditions
- Wound Surgical, Wound Heal, Oral Soft Tissue Conditions
- Trial name
- NCT04202822
- Testing
- Oral soft tissues biopsies
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Roma La Sapienza
Arthroscopic Knee Repair, Arthroscopic Hip Repair
PO Methadone Ortho Outpatient
The goal of this clinical trial is to learn if oral methadone given before surgery works to minimize post-operative pain and opioid usage.
- Trial name
- NCT06351215
- Testing
- Methadone group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Keck School of Medicine of USC
Scars
Safety and Efficacy of SLI-F06 in Wound Healing and Scar Appearance
Multicenter, double-blind study comparing SLI-F06 to vehicle formulation buffer for the improvement in scar appearance and wound strength in routine surgical excisions, as well as post-operative abdominoplasty scar appearance.
- Trial name
- NCT03880058
- Testing
- SLI-F06, Formulation buffer
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Scarless Laboratories, Inc.
Peritoneal Surface Malignancy, Postoperative Adhesion
SurgiPerito Trial: High-Purity Type-I Collagen for Peritoneal Reconstruction After Cytoreductive Surgery
This dual-centre, randomized controlled trial evaluates the safety and efficacy of high-purity Type-I collagen-based biomaterial, as a peritoneal substitute following peritonectomy in patients undergoing cytoreductive surgery…
- Conditions
- Peritoneal Surface Malignancy, Postoperative Adhesion, Bowel Obstruction, Wound Complications
- Trial name
- NCT07241091
- Testing
- High-Purity Type-I Collagen Scaffold, Standard Peritonectomy Closure
- Where
- 2 sites in India
- Volunteers
- 60 people
- Sponsor
- Adichunchanagiri Institute of Medical Sciences, B G Nagara
Anal Wound
Impact of Topical Antiadhesion Therapy on Wound Healing and Postoperative Pain After Anal Surgery
2QR-complex is a patented molecule extracted from Aloe vera barbadensis leaves that blocks the adhesion of pathogenic microbes to human epithelial cells and tissues [9].
- Trial name
- NCT04275596
- Testing
- 2QR complex
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Perianal Abscess
Effect of Different Sitz Bath Methods on Perianal Abscess After Surgery
Perianal abscess is a purulent infection of the tissues surrounding the anal canal and rectum. The postoperative wound is prone to infection, and the literature indicates that hip bathing is helpful to prevent infection, reduce…
- Trial name
- NCT07142382
- Testing
- Ordinary sitz bath, manual flushing sitz bath, electric flushing sitz bath
- Where
- China
- Volunteers
- 102 people
- Sponsor
- The Affiliated Hospital of Putian University
Aortic Aneurysm
Melatonin and Cardiac Outcome After Major Surgery
The purpose of this study is to assess whether treatment with melatonin can reduce cell damage and inflammatory stress response and thereby occurrence of myocardial injury after abdominal aortic surgery.
- Trial name
- NCT00315926
- Testing
- Melatonin
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Pain, Rotator Cuff
Single Shot vs Continuous Interscalene Block for Rotator Cuff Repair
1. Rotator cuff have painful post surgery recovery. 2. Single shot interscalene with oral analgesics may or may not be enough 3. Continuous nerve block may be too much for the surgery 4.
- Conditions
- Pain, Rotator Cuff, Surgery
- Trial name
- NCT01122745
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Chicago
Healing of the Wound After Rectovaginal Fistula Surgery
the Method of Cotton Padding Promoting the Rectovaginal Fistula Surgery
The method of Cotton Padding (mCP) was summarized by combining with many years clinical experience and the traditional ancient books.The mCP could be used in Rectovaginal Fistula (RVF) post operation effectively,in order to…
- Trial name
- NCT05138965
- Testing
- the mCP with alginates dressing, only alginates dressing
- Where
- 3 sites in China
- Volunteers
- 20 people
- Sponsor
- China Academy of Chinese Medical Sciences
Gingival Enlargement
Efficacy of Hyaluronic Acid Gel and Photobiomodulation on Wound Healing After Surgical Gingivectomy
The aim of this study was to evaluate the effect of hyaluronic acid gel after photobiomodulation on the healing of surgical gingivectomy sites
- Trial name
- NCT05787912
- Testing
- Photobiomodulation, Hyaluronic acid after photobiomodulation
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Orthopedics, Traumatology
Influence of an Anti-osteoporotic Drug on Healing After Surgical Repair of Chronic Rotator Cuff Lesions of the Shoulder
This is a prospective, single-center, placebo-controlled, non-comparative, phase II study to evaluate the influence of an adjuvant, intravenous therapy with zoledronic acid (single dose) on healing after arthroscopic repair of…
- Trial name
- ZORRO (NCT05677152)
- Testing
- Intravenous Infusion of Aclasta®
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- AUVA Traumazentrum Vienna Site UKH Meidling