Clinical trials: Post-thoracotomy Pain
Postoperative Pain
Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control
This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients…
- Trial name
- NCT07763249
- Testing
- Continuous Thoracic Paravertebral Block, Continuous Thoracic Epidural Block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Post-thoracotomy Pain, Acute Post-thoracotomy Pain
Intraoperative Cryoanalgesia for Extended Pain Management Following Thoracotomy
The ICE Study study will compare standard therapy (thoracic epidural) versus a novel approach (Cryoanalgesia combined with thoracic epidural) in subjects undergoing unilateral thoracotomy.
- Conditions
- Chronic Post-thoracotomy Pain, Acute Post-thoracotomy Pain, Post-thoracotomy Pain Syndrome
- Trial name
- ICE (NCT03538340)
- Testing
- Thoracic Epidural, Intercostal Cryoanalgesia
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- University of Maryland, Baltimore
Post-operative Pain, Respiratory Depression
Dexmedetomidine for the Control of Post-Operative Pain in Thoracotomy Patients
The purpose of this study is to evaluate the safety, efficacy, hemodynamic and respiratory stability of a low-dose of dexmedetomidine infusion in post-operative surgical in-patients undergoing thoracic surgery after discharge…
- Trial name
- NCT00345384
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Baylor Research Institute
Thoracic Anesthesia, Thoracotomy
Opioid Consumption After Thoracotomy and Factors Affecting Postoperative Acute Pain
Thoracic surgery operations constitute a significant portion of surgical procedures performed in hospitals. In the United States, more than 50,000 thoracic surgical procedures are performed annually, and more than 80% of these…
- Conditions
- Thoracic Anesthesia, Thoracotomy, Opioid, Postoperative Pain Management
- Trial name
- NCT07329855
- Testing
- Opioid Analgesic, Pain Medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Pain Following Thoracotomy Surgery
Study of Exparel Versus Epidural for Pain Control After Thoracotomy
Unilateral intercostal nerve blocks provide pain control as effectively as a continuous thoracic epidural, and will a lower incidence of side effects.
- Trial name
- NCT02178553
- Testing
- Epidural, Intercostal Bupivicaine (Exparel)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Mayo Clinic
Thoracic Diseases
Comparison of Continuous Erector Spina Plane Block With Intercostal Block in Acute and Chronic Pain Control After Thoracotomy
Thoracotomy is associated with severe postoperative pain due to surgical incision, rib retraction or resection, and intercostal nerve damage.
- Trial name
- NCT04309630
- Testing
- intercostal block, erector spina plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara University
Postoperative Pain
NSAIDs With Morphine-PCA Compared to Epidural Analgesia in Thoracotomy Pain
The investigators investigated whether a strictly controlled pain management with patients participating in a clinical study can attenuate persistence of post-thoracotomy pain.
- Trial name
- NCT01541137
- Testing
- Diclofenac, parecoxib/ valdecoxib, patient controlled epidural analgesia
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital
Pain
The cryoICE™ CryoAnalgesia Study For Pain Management in Post thoRacic Procedures Via intercOSTal Cryoanalgesia (FROST)
The investigators propose to assess whether intra-operative intercostal cryoanalgesia using the cryoICE® probe (AtriCure®, Inc., 7555 Innovation Way, Mason, Ohio) provides superior post-operative analgesic efficacy as compared to…
- Trial name
- FROST (NCT02922153)
- Testing
- Cryoanalgesia, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 84 people
- Sponsor
- AtriCure, Inc.
Shoulder Pain
Superficial Cervical Plexus Block for Shoulder Pain After Lung Surgery
The investigators want to know whether injecting numbing medication on the side of the neck (also called superficial cervical plexus block) can prevent or reduce shoulder pain that patients commonly experience after lung surgery.
- Trial name
- SCPB (NCT01550302)
- Testing
- Superficial Cervical Plexus Block, Bupivacaine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Washington
Pain, Postoperative, Opioid Use
Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain
The goal of this pilot study is to describe and compare Ultrasound-Guided Erector Spinae Plane (ESP) Blocks using Exparel® (bupivacaine liposome injectable suspension) to Marcaine® (bupivacaine hydrochloride) for pain management…
- Conditions
- Pain, Postoperative, Opioid Use, Perioperative Complication, Heart Diseases
- Trial name
- NCT06077422
- Testing
- bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Rutgers, The State University of New Jersey
Post Operative Pain
Post-Operative Kinesio Taping Impact on Pain in Thoracotomy vs Thoracoscopy
The project is of a comparative nature. It seeks to study pain reduction following two forms of chest surgery and compare results between both procedures. It will use kinesio taping as the studied pain reducer.
- Trial name
- NCT05200689
- Testing
- Kinesiotaping (KT)
- Where
- 5 sites in Egypt, Italy and 2 more
- Volunteers
- 310 people
- Sponsor
- Al-Quds University
Lung Cancer
Neuropathic in the Acute Post Operative Phase
Investigation of thermal thresholds and sensory mapping to thermal stimuli
- Trial name
- NCT01300702
- Where
- 2 sites in Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post-thoracotomy Pain Syndrome
Effects of Intravenous Acetaminophen in Patients Undergoing Thoracoscopic Surgery
This is a single-center, randomized, double-blind, placebo-controlled trial. A total of 100 patients, 50 per treatment arm, undergoing minimally invasive thoracic surgery will be randomized 1:1 across 2 treatment arms: Ofiramev®…
- Trial name
- IVTylenol (NCT03051932)
- Testing
- Ofiramev® (IV Acetaminophen)
- Sponsor
- The University of Texas Medical Branch, Galveston
Laser Therapy, Post Thoracotomy Pain
Laser Therapy in the Treatment of Post Thoracotomy Pain; A Pilot Study
The purpose of this study is to demonstrate the safety of the AvicennaTM class IV laser for application over the skin of human subjects.
- Trial name
- NCT00623909
- Testing
- AvicennaTM class IV laser application
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Pain, Acute, Breathing, Mouth
Combined Acupressure Effects on Post-Thoracotomy Pain and Lung Volume
Pain is a subjective, sensory and emotionally unpleasant experience resulting from real or hidden injuries in tissues. The pain experience is a subjective and unique experience in physiological and psychological terms and is the…
- Conditions
- Pain, Acute, Breathing, Mouth, Relaxation; Diaphragm, Cough
- Trial name
- NCT07411417
- Testing
- Acupressure group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Özgül Aydemir
Pain, Postoperative, Surgery, Thoracic
Influence of Preoperative Support on Anxiety, Pain and Satisfaction With Postoperative Analgesia
The aim of this study was to analyze a relationship between information support provided by an interdisciplinary team and the levels of anxiety, pain and satisfaction with postoperative analgesia in children and adolescents…
- Trial name
- NCT03488459
- Testing
- Routine preoperative information from a nurse, Additional information support from a psychologist
- Where
- Poland
- Volunteers
- 112 people
- Sponsor
- National Institute for Tuberculosis and Lung Diseases, Poland
Post-thoracotomy Pain
Duloxetine Role in Reducing Opioid Consumption After Thoracotomy
A total of 60 patients scheduled for thoracotomy with the aim of excision of pleural or lung cancer, will be randomized by the use of a computer-generated table of random numbers to receive duloxetine 60 mg orally 2 hours before…
- Trial name
- NCT03618225
- Testing
- Oral Duloxetine 60mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Thoracotomy, Pain
The Effects of Soy Protein on Post-thoracotomy Pain
This study seeks to determine whether soy protein supplements reduce the pain that often occurs following surgery for a lung tumor.
- Trial name
- NCT00344097
- Testing
- Soy protein
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Post Thoracic Surgery
Intrapleural Bupivacaine for Ipsilateral Shoulder Pain After Thoracotomy
While thoracic epidural could control incisional pain after thoracotomy, an excruciating ipsilateral shoulder pain happens post thoracotomy and could affect up to 85% of thoracotomy patients.
- Trial name
- NCT03862404
- Testing
- Bupivacaine-epinephrine, Normal saline
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Post-operative Intercostal Neuralgia
Minocycline for the Prevention of Post-operative Intercostal Neuralgia
In about half the patients who have an open chest surgery there is persistent severe pain in the chest. The investigators are examining whether minocycline, a commonly used antibiotic, will prevent pain.
- Trial name
- NCT01314482
- Testing
- Minocycline
- Where
- Australia
- Volunteers
- 116 people
- Sponsor
- University of Adelaide