Clinical trials: Posterior Capsule Opacification
Posterior Capsule Opacification After Phacoemulsification and IOL Implantation
Long-term Evaluation of Single-piece ACrysof IOL Implantation on Development of Posterior Capsule Opacification
Although contemporary cataract surgery has made tremendous strides in technological advancement, posterior capsular opacification (PCO) is still the most frequent long-term complication leading to decreased visual functions and…
- Trial name
- NCT01820065
- Testing
- Cataract surgery with IOL implantation
- Where
- India
- Volunteers
- 390 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract
Posterior Capsule Opacification Study
First object is to compare square edge PMMA with round edge PMMA IOL where the materials are same. Next objective is to compare square edge PMMA IOL with Acrysof IOL where the materials are different
- Trial name
- NCT00312299
- Testing
- Square edge PMMA IOL, Round edge PMMA IOL, Acrysof IOL
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Aurolab
Posterior Capsule Opacification, Pseudophakia
IOL Position and Refractive Change After Nd:YAG Laser Posterior Capsulotomy
After cataract surgery, the thin natural membrane that holds the artificial lens in place can slowly turn cloudy. This is called posterior capsule opacification. It makes vision blurry and can cause glare.
- Conditions
- Posterior Capsule Opacification, Pseudophakia, Refractive Errors
- Trial name
- YAG-IOL-POS (NCT07802145)
- Testing
- Nd:YAG laser posterior capsulotomy, Anterior segment swept-source OCT, Swept-source optical biometry
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Vienna Hospital Association
Capsule Opacification, Pseudophakia
Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two Microincision IOLs: Hoya iMics NY-60 vs Acrysof SN60WF
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. In the UK, more than half of people who are over 65 have some cataract development in one or both eyes.
- Conditions
- Capsule Opacification, Pseudophakia, Cataract
- Trial name
- NCT01732484
- Testing
- intraocular lens implantation
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Cataract, Postoperative Complications
Validation of an Artificial Intelligence System for Postoperative Management of Cataract Patients
Cataract surgery is the current standard of management for cataract patients, which is typically succeeded by a postoperative follow-up schedule.
- Conditions
- Cataract, Postoperative Complications, Artificial Intelligence
- Trial name
- NCT04138771
- Testing
- An artificial intelligence system for postoperative management of cataract patients
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-sen University
Dysphotopsia, Posterior Capsule Opacification
Clinical Evaluation of Low Contrast Visual Performance and Low Light Phenomena in Patients With Various Intraocular Lens Implants
The goal of this clinical investigation is to evaluate visual acuity and contrast sensitivity in low lighting conditions using several different testing devices, and measure nighttime side effects of intraocular lens (IOL)…
- Conditions
- Dysphotopsia, Posterior Capsule Opacification, Visual Acuity, Visual Function
- Trial name
- NCT07213167
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Dr. Daniel H. Chang, MD
Posterior Capsule Opacification
Influence of CleaRing Open-capsule Device on Refractive Predictability in Cataract Patients (Part 2)
The Hanita CleaRing device is an intraocular implant designed for inhibition of PCO leading to reduction in the Nd:YAG treatment rate.
- Trial name
- CleaRing (NCT06083025)
- Testing
- CleaRing
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Hanita Lenses
Posterior Capsule Opacification, Cataract
Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two IOLs: Hoya iMics Y-60H vs. Bausch&Lomb MI60 (MIMI)
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. The only treatment that can restore functional visual ability is cataract surgery where the opacified crystalline lens is removed by…
- Trial name
- NCT01786356
- Testing
- HOYA iMics Y-60H, B&L MI60
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Posterior Capsule Opacification
Posterior Capsule Opacification Following Cataract Surgery With Implantation of the MICS IOL L313
This study collects intra- and postoperative data from the patients´charts retrospectively and evaluates retro- and prospectively the rate of posterior capsule opacification (PCO) following implantation of the intraocular lens L…
- Trial name
- NCT03184428
- Testing
- Postoperative observation and survey
- Where
- Germany
- Volunteers
- 3,785 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Cataract, Pediatric Cataract
AquaLase Capsule Wash for Pediatric Eyes
To determine whether AquaLase capsule wash reduces posterior capsule opacification (PCO) in pediatric eyes.
- Trial name
- NCT00756327
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
Dextenza Within Upper Lid Canaliculus Compared With Lower Lid Canaliculus Following Bilateral Cataract Extraction Surgery With PCIOL.
Assessing DEXTENZA efficacy when placed within the upper eyelid canaliculus as opposed to the lower eyelid canaliculus.
- Trial name
- NCT04592081
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kerry Assil, MD
Cataract
Influence of Two Different Preloaded Intraocular Lens (IOLs) on Posterior Capsule Opacification
Studies showed that a sharp posterior optic edge of an intraocular lens (IOL) inhibits migration of lens epithelial cells in between posterior capsule and optic of the IOL and therefore reduces the rate of posterior capsule…
- Trial name
- NCT00673803
- Testing
- cataract surgery
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Hospital Hietzing
Posterior Capsule Opacification Obscuring Vision
Efficacy and Outcomes of Neodymium-doped Yttrium Aluminum Garnet (Nd: YAG) Laser Capsulotomy Performed by Optometrists
The purpose of this study is to formally assess the efficacy and outcomes of optometrist-performed neodymium-doped yttrium aluminum garnet (Nd: YAG) laser capsulotomy procedures.
- Trial name
- NCT04027595
- Testing
- Neodymium-doped Yttrium Aluminum Garnet (Nd: YAG) Laser Capsulotomy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Northeastern State University
Development of Posterior Capsule Opacification
Evaluation of Posterior Capsule Opacification in Eyes With Diabetes Mellitus
To compare the development of posterior capsule opacification (PCO) between eyes with and without a history of diabetes mellitus (DM) after single-piece hydrophobic acrylic intraocular lens (IOL) implantation 4 years…
- Trial name
- DM & PCO (NCT01480934)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Posterior Capsule Opacification, Cataract
Posterior Capsule Opacification Development With Two Different Intraocular Lenses
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. The only treatment that can restore functional visual ability is cataract surgery where the opacified crystalline lens is removed by…
- Trial name
- MIPHY (NCT01734343)
- Testing
- HOYA iMics Y-60H, PhysIOL microAY
- Where
- Austria
- Volunteers
- 65 people
- Sponsor
- Medical University of Vienna
Cataract, Posterior Capsule Opacification
Two Different Cataract Surgical Procedures to Prevent Posterior Capsule Opacification
In this study, the investigators introduce a new "capsule-reserved" cataract surgical procedure in which anterior lens capsule is reserved and attached onto posterior lens capsule in the purpose of preventing posterior capsule…
- Trial name
- NCT02445274
- Testing
- Anterior lens capsule was reserved
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Sun Yat-sen University
Posterior Capsule Opacification, Ocular Hypertension
Brinzolamide/Brimonidine Combination vs Brimonidine 0.2% in the Prevention of IOP Rise After Nd-YAG Laser Capsulotomy
To compare the efficacy of a Brinzolamide/Brimonidine fixed combination (FC) with Brimonidine 0.2% in preventing intraocular pressure (IOP) elevations after neodymium: yttrium-aluminum-garnet (Nd:YAG) laser posterior capsulotomy.
- Trial name
- NCT03192826
- Testing
- Brinzolamide/Brimonidine FC, Brimonidine 0.2%, Artificial tears
- Where
- Greece
- Volunteers
- 79 people
- Sponsor
- University Hospital of Patras
Cataract, Pseudophakia
Effect of Optic Edge Design in a Silicone Intraocular Lens on Posterior Capsule Opacification
Purpose: To compare the posterior capsule opacification (PCO) inhibiting effect of the sharp posterior optic edge design of the Clariflex silicone intraocular lens (IOL) with that of the double-round edge design of the SI40…
- Trial name
- NCT00428363
- Testing
- Cataract surgery with implantation of an intraocular lens
- Where
- Austria
- Volunteers
- 52 people
- Sponsor
- Medical University of Vienna
Posterior Capsule Opacification
Novel Technique of Pneumatic Posterior Capsulorhexis for Treatment and Prevention of Posterior Capsular Opacification
ABSTRACT PURPOSE: To evaluate a new technique of posterior capsulorhexis using air support to treat primary posterior capsular opacification (PCO) during cataract extraction surgery or to prevent post-operative PCO.
- Trial name
- PCO (NCT04007965)
- Testing
- Pneumatic Posterior Capsulorhexis
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Minia University
Posterior Capsule Opacification
Refraction Changes After Using ND: YAG LASER In Treatment of Posterior Capsular Opacification In Pseudo Phakic Eye
The most prevalent long term consequence of cataract surgery in both phacoemulsification and extracapsular cataract excision is posterior capsular opacification (PCO) PCO occurred in 11.8 percent of patients one year after…
- Trial name
- NCT05501535
- Testing
- ND:YAG LASER
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University