Clinical trials: Postinduction Hypotension
Hypertension, Fentanyl
Lidocaine Versus Fentanyl for Hemodynamic Stability
Hypertension is an important health challenge that affects millions of people across the world today and is a major risk factor for multiple system comorbidities. Intraoperative hypotension may lead to negative outcomes.
- Conditions
- Hypertension, Fentanyl, Lidocaine
- Trial name
- NCT06557473
- Testing
- Lidocaine IV, Fentanyl
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Theodor Bilharz Research Institute
Postinduction Hypotension
Continuous Versus Bolus Norepinephrine Administration to Treat Postinduction Hypotension
INDUCT-Multi is a multicenter randomized trial investigating whether continuous, compared to bolus, administration of norepinephrine during induction of general anesthesia reduces postinduction hypotension in high-risk…
- Trial name
- INDUCT-Multi (NCT07538388)
- Testing
- Continuous Norepinephrine Administration
- Where
- 4 sites in Germany
- Volunteers
- 446 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Postinduction Hypotension, Hypotension During Surgery
The Effect of Preoperative Intravenous Fluid Bolus on Post-induction Hypotension in Elective Cystoscopies.
This study aims to determine whether a standardized, weight-based crystalloid fluid bolus administered preoperatively reduces the incidence of postinduction hypotension (PIH) in patients undergoing cystoscopy.
- Trial name
- NCT06985654
- Testing
- Lactated Ringers
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Missouri-Columbia
Blood Pressure, Perioperative Hypotension
Effect of Continuous Invasive Blood Pressure Monitoring on Postinduction Hypotension in Patients Having Major Surgery
This is a randomized trial (1) investigating whether continuous invasive arterial blood pressure monitoring using an arterial catheter reduces the area under a mean arterial pressure (MAP) of 65 mmHg within the first 15 minutes…
- Conditions
- Blood Pressure, Perioperative Hypotension, Postinduction Hypotension
- Trial name
- NCT04894019
- Testing
- Continuous invasive blood pressure monitoring, Intermittent non-invasive blood pressure monitoring
- Where
- Germany
- Volunteers
- 242 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hypotension Drug-Induced, Anesthesia
Pre-op Fluid Study
Theoretical framework: Hypotension during surgery directly impacts patients' postoperative outcomes and complications. Decrease in blood pressure measurements secondary to anesthetic drugs is an expected scenario in most surgical…
- Trial name
- NCT05079269
- Testing
- Crystalloid Solutions
- Where
- 2 sites in Austria
- Volunteers
- 550 people
- Sponsor
- Medical University of Graz
Postinduction Hypotension
Intermittent Ephedrine Boluses for Prophylaxis Against Postinduction Hypotension
The aim of this work is to assess the efficacy of intermittent ephedrine boluses in prophylaxis against postinduction hypotension in high-risk patients undergoing major abdominal surgery, compared to standard care.
- Trial name
- NCT07722013
- Testing
- Normal Saline, Ephedrine
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Cairo University
Post-induction Hypotension
Comparison of the Hemodynamic Effect of Three Positions During Induction of Anesthesia
The most common methods for prevention of post-induction hypotension are preoperative fluid loading and vasopressors. Leg elevation induces an intrinsic transfusion of 150 mL blood from the lower limbs to the central fluid…
- Trial name
- NCT03996213
- Testing
- head down position, leg elevation position
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Cairo University
Hypotension
Efficacy of Dexamethasone in Attenuation of Postinduction Hypotension in Geriatric Patients Undergoing General Anesthesia
Geriatric patients who undergo general anesthesia experience post induction hypotension which is treated with intravenous fluids and ephedrine.
- Trial name
- NCT04908592
- Testing
- Dexamethasone
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Post-induction Hypotension, Intestinal Obstruction
SV and IVC Collapsibility Index to Predict Postinduction Hypotension
Postinduction hypotension (PIH) is a frequent complication during general anesthesia. This study aims to compare the predictive effectiveness and diagnostic accuracy of stroke volume (SV) measured via left ventricular outflow…
- Trial name
- NCT07742904
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Hypotension on Induction
Perfusion Index as a Predictor of Postinduction Hypotension of General Anesthesia in Geriatric Patients
The influence of hemodynamic aberrations during anesthesia on adverse outcomes is an important clinical issue. There is evidence that hypotension and hypertension during general anesthesia are independently associated with…
- Trial name
- NCT04682717
- Testing
- perfusion index monitoring for postinduction hypotension
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypotension, Anesthesia
Avoiding Postinduction Hypotension: the Clinical ZERO-HYPOTENSION Proof-of-concept Study
In this clinical proof-of-concept study, the aim is to investigate the efficacy of a hypotension avoidance strategy to prevent post-induction hypotension.
- Conditions
- Hypotension, Anesthesia, Hypotension on Induction
- Trial name
- NCT05842759
- Testing
- Monitoring, Norepinephrine preparation, Propofol administration
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Postinduction Hypotension, Elderly
Opioid-based Versus Lidocaine-based Induction of Anesthesia With Propofol in Elderly
Advances in the medical service and public health increased longevity; hence, more elderly patients (>65 years) are encountered by the anesthetists for variety of surgical interventions.
- Trial name
- NCT05051007
- Testing
- fentanyl, Lidocaine IV
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kasr El Aini Hospital
Hypotension on Induction, Emergency Surgery
5 Versus 10 mcg Norepinephrine Bolus in Treatment of Postinduction and Early Intraoperative Hypotension in Emergency Abdominal Surgery
Postinduction hypotension is a frequent intraoperative complication, particularly in emergency abdominal surgery due to factors such as sepsis, hypovolemia, and limited preoperative cardiac assessment.
- Conditions
- Hypotension on Induction, Emergency Surgery, Norepinephrine
- Trial name
- NCT07719075
- Testing
- Norepinephrine 10 mcg, Norepinephrine 5 mcg
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Cairo University