Clinical trials: Postmenopausal Disorder
Breast Cancer, Aromatase Inhibitors
Combined Training on Body Composition of Postmenopausal Women Undergoing Treatment for Breast Cancer
Breast cancer is a multifactorial disease affecting women, and one of the treatments for its healing and survival is hormone therapy.
- Conditions
- Breast Cancer, Aromatase Inhibitors, Postmenopausal
- Trial name
- NCT02804308
- Testing
- Combined Training
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Obesity
Effect of Whole-grape Powder on Body Composition, Fat and Bone Serum Biomarkers in Postmenopausal Women
The purpose of the study is to provide whole-grape powder or a placebo as a supplement to postmenopausal women for 12 weeks to determine the effects on body composition and bone formation.It is hypothesized that 12 weeks of…
- Trial name
- NCT01717820
- Testing
- Freeze-dried whole-grape powder
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Metabolic Syndrome, Postmenopausal Disorder
Inofolic NRT and the Metabolic Syndrome
A prospective, randomized, controlled, open-label study will be carried out on 80 post-menopausal women affected by the metabolic syndrome (criteria are described in NIH ATP III).
- Trial name
- NCT01400724
- Testing
- Inofolic NRT
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Messina
Elderly, Hormones
Aerobic Exercise With Diet Induces Hormonal, Metabolic, and Psychological Changes
PURPOSE: to determine the effect of aerobic exercise training and diet on sex hormones , insulin resistance and depression and if is there correlation between these factors effect in postmenopausal obese women BACKGROUND: The…
- Conditions
- Elderly, Hormones, Insulin Resistance, Depression
- Trial name
- NCT05136742
- Testing
- aerobic exercise and diet program, diet program
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postmenopausal Osteoporosis
CLCF1 Gene Associated With Postmenopausal Osteoporosis of Kidney Yin Deficiency Syndrome
For nearly 112 million patients with osteoporosis in China, it is of great significance for preventing and treating by clearly understanding the molecular mechanism of kidney deficiency.
- Trial name
- PMOP (NCT02981732)
- Testing
- Liuwei Dihuang Pill
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- xuhuijuan
Insulin Resistance, Obesity
Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity
A combination of generally regarded as safe (GRAS) compounds named GLY-LOW, which included: alpha lipoic acid, pyridoxamine, nicotinamide, piperine and thiamine, were examined in pre-clinical experiments.
- Conditions
- Insulin Resistance, Obesity, Cardiovascular Diseases, Cognitive Impairment
- Trial name
- NCT06242535
- Testing
- GLY-LOW
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hoskinson Health and Wellness Clinic
Complementary Alternative Medicine, Menopause
Therapeutic Touch and Foot Reflexology on Sleep Quality and Menopausal Symptoms
This randomized controlled trial was designed to compare the effects of therapeutic touch and reflexology on sleep quality and menopausal symptoms in postmenopausal women affected by the February 6, 2023 Kahramanmaraş…
- Conditions
- Complementary Alternative Medicine, Menopause, Sleep Disturbance
- Trial name
- NCT07767318
- Testing
- Therapeutic Touch, Foot Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Osmaniye Korkut Ata University
Stress Urinary Incontinence
Urethral Rotation Angles and Foot Pronation Mechanical Changes in Postmenopausal Women
Stress urinary incontinence (SUI) occur secondary to increased intra abdominal pressure, that directed the researchers to study the mechanical changes in urethra and bladder that associated with it.
- Trial name
- NCT06576791
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cardiovascular Diseases, Coronary Disease
Effects of Training Intensity on the CHD Risk Factors in Postmenopausal Women
The purpose of this research is to find out whether training at different exercise intensities reduces the risk of developing cardiovascular disease (CVD) to a different extent.
- Trial name
- NCT00000108
- Testing
- Exercise
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Vitamin D Deficiency
The Impact of Severe Vitamin D Deficiency and Its Correction on Bone Mineral Density (BMD) in Postmenopausal Women
It is well known that postmenopausal women are at risk for osteoporosis. The study hypothesis is that vitamin D deficiency (≤17.5nmol/L) is frequently associated with osteomalacia and will cause low BMD estimation in DXA scan due…
- Trial name
- Vitamin D (NCT01694355)
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Atrophic Vaginitis, Menopause
Vaginal and Urinary Microbiome Trial
A randomized controlled trial looking at the effects of vaginal estrogen and a nonhormonal alternative on the vaginal and urinary microbiome in women with genitourinary syndrome of menopause.
- Conditions
- Atrophic Vaginitis, Menopause, Recurrent Urinary Tract Infections
- Trial name
- NCT02869165
- Testing
- Conjugated equine estrogen topical cream, Apricot kernel oil
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Postmenopausal Osteoporosis
Study on the microRNA Expression Level in Postmenopausal Osteoporosis
The miRNA plays an important regulation role in gene expression, and also closely related to bone metabolism. Previous research found that postmenopausal osteoporosis with kidney Yin deficiency syndrome (POP) is associated with…
- Trial name
- microRNA (NCT02128009)
- Testing
- osteoporosis
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fujian Academy of Traditional Chinese Medicine
Vitamin D Deficiency, Osteoporosis
Change in Free 25(OH)D After High Dose in Vitamin D Deficient Postmenopausal Women
Total 25(OH)D is currently used as a biomarker of vitamin D status. However, there is some debate as to whether total 25(OH)D is the best marker to use.
- Trial name
- NCT02553044
- Testing
- Cholecalciferol (Vitamin D3)
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Perimenopausal Bone Loss
Natto Supplementation to Prevent Loss of Bone Mass in Women Immediately After Menopause
Study Objective: To determine whether Natto supplementation in women immediately after menopause might prevent severe bone loss Study population: Women 50 - 60 years, 1-5 years after menopause Study Design: Double-blind…
- Trial name
- NCT00290212
- Testing
- Natto capsules (food suppl.) cont. 360 microg. vit K2/day
- Where
- 2 sites in Norway
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Sex Behavior
Safety Study of Transdermal Testosterone for Low Libido in Pre and Postmenopausal Women
Female sexual dysfunction (FSD) is an established side effect of Selective serotonin reuptake inhibitors (SSRIs) and serotonin noradrenalin reuptake inhibitors (SNRIs), causing symptoms such as loss of libido, arousal…
- Trial name
- TESTOSTERONE (NCT02215434)
- Testing
- Testosterone, Transdermal, Behavior
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Potiguar
Postmenopausal Women
Everolimus and/or Exercise to Prevent Bone Loss in Postmenopausal Women
It is estimated that women lose around 20-25% of bone mass during the 5-10 years period of postmenopausal transition, and menopause is considered a major risk factor for osteoporotic fragility fracture.
- Trial name
- RapaLoad (NCT06789900)
- Testing
- Everolimus (Afinitor®), Football Fitness Concept
- Where
- Denmark
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Hypertension, Dyslipidemia
Effect of Pumpkin Seed Oil or Pumpkin Seeds on Blood Pressure and Menopausal Symptoms in Postmenopausal Women
The purpose of this randomized control trial is to compare the effect of pumpkin seed oil 2g/day with pumpkin seeds given as a dose of 1½ teaspoons/ 4.1 grams a day to provide 2g of lipid (equivalent to 2 grams of oil) on BP…
- Trial name
- NCT02727036
- Testing
- Pumpkin seed oil, Pumpkin seeds
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Postmenopausal Flushing, Cardiovascular Risk Factor
Hot Flash as a Marker of Cardiovascular Risk in Recent Postmenopause: Effects of Non-hormonal Treatments
Hot flashes, vasomotor symptoms that affect many postmenopausal women, are associated with cardiovascular disease and endothelial dysfunction.
- Conditions
- Postmenopausal Flushing, Cardiovascular Risk Factor, Endothelial Dysfunction
- Trial name
- NCT03149419
- Testing
- Paroxetine
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Cardiovascular Disease, Osteoporosis
The Effect of Soy Isoflavone Supplementation on Endothelial Function
A randomized double blind controlled trial was conducted to evaluate the effect of daily supplementation with soy isoflavone 100 mg/day for 12 months on 182 postmenopausal women aged 47 to 60 years at subdistrict South Jakarta…
- Trial name
- NCT01463436
- Testing
- soy isoflavone, control group
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Trisakti University
Postmenopausal Osteoporosis
The Deferasirox-calcium-vitamin D3 Therapy for Postmenopausal Osteoporosis (PMOP)
In 2006, Weinberg proposed a hypothesis that iron accumulation was a risk factor for osteoporosis. Osteoporosis is a common complication in various diseases, such as hemochromatosis, African hemosiderosis, thalassemia, and sickle…
- Trial name
- PMOP (NCT02854722)
- Testing
- Deferasirox and calcium-vitamin D3, Calcium-vitamin D3
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Soochow University