Clinical trials: Postoperative Death
Organ Transplantation, Immunosuppressive Agents
Immunosuppressants to Postoperative Infection and Death
The goal of this observational study is to explore the different immunosuppressive agents and related outcomes in organ transplantation patients in Taiwan.
- Conditions
- Organ Transplantation, Immunosuppressive Agents, Cohort Study
- Trial name
- NCT06121804
- Testing
- Immunosuppressive Agents
- Where
- Taiwan
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Elective Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after elective surgery.
- Trial name
- NCT04929886
- Where
- 5 sites in China
- Volunteers
- 1,000,000 people
- Sponsor
- Huazhong University of Science and Technology
Hepatocellular Carcinoma
SHR-1210 Plus Apatinib in Patients With Hepatocellular Carcinoma After Surgery
SHR-1210 is a humanized anti-PD1 Immunoglobulin G4 (IgG4) monoclonal antibody. This is an open- label，single center ，non-randomized ，Single Arm Exploratory Study .
- Trial name
- NCT03722875
- Testing
- SHR-1210, apatinib
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Shanghai Zhongshan Hospital
Heart Diseases, Death
Registry for the Improvement of Postoperative OutcomeS in Cardiac and Thoracic surgEry
The registry for the improvement of postoperative outcomes in cardiac and thoracic surgery aims to prospectively collect data in order to test the association between various preoperative and per-operative variables ; and several…
- Conditions
- Heart Diseases, Death, Postoperative Complications, Cardiac Complication
- Trial name
- RIPOSTE (NCT03209674)
- Testing
- Cardiothoracic surgery
- Where
- France
- Volunteers
- 8,000 people
- Sponsor
- CMC Ambroise Paré
Postoperative Mortality, Anesthesia
The Study of Anesthesia-related Risk Factors for Postoperative Death in Elderly Non-cardiac Surgery Patients in China
At present, the elderly population in China has reached 241 million, and there are more than 20 million elderly surgical patients every year, accounting for about 25% of the surgical population.
- Conditions
- Postoperative Mortality, Anesthesia, Elderly Patients, Noncardiac Surgery
- Trial name
- NCT04389008
- Testing
- no interventions
- Where
- China
- Volunteers
- 300,000 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Cardiovascular Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after cardiac and vascular surgery.
- Trial name
- NCT04926012
- Where
- 5 sites in China
- Volunteers
- 100,000 people
- Sponsor
- Huazhong University of Science and Technology
Kidney Transplantation, Acute Kidney Tubular Necrosis
Effect of BM-MSCs on Early Graft Function Recovery After DCD Kidney Transplant.
This study is designed to investigate whether allogeneic bone marrow-derived mesenchymal stem cells (BM-MSCs) can promote function recovery in patients with poor early graft function after kidney transplantation from Chinese…
- Trial name
- NCT02563366
- Testing
- BM-MSCs, Saline
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Postoperative Complications, Complications of Surgical Procedures or Medical Care
Effects of Checklists in Surgical Care - a Study on Complications, Death and Quality of Patient Administrative Data
This project aims to produce a systematic review on present knowledge on effects of using safety checklists in medicine. Implementation of a checklist system throughout surgical care may reduce patient morbidity and mortality.
- Trial name
- NCT01872195
- Testing
- The comprehensive patient safety checklist system
- Where
- Norway
- Volunteers
- 21,000 people
- Sponsor
- Haukeland University Hospital
Cardiology, Critical Care Medicine, Emergency Medical Service
TIMECARD(TaIwan Network of Post-arrest ManagEment for CARDiac Arrest)IIRegistry
This study aims to collect the post-cardiac arrest patients with ICU admission.
- Trial name
- TIMECARDII (NCT06218329)
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- National Taiwan University Clinical Trial Center
Hypotension, Postoperative Complications
Biomarkers, Blood Pressure, BIS: Risk Stratification/Management of Patients at Cardiac Risk in Major Noncardiac Surgery
Major adverse cardiovascular events (MACE) are a leading cause of serious complications and death following major noncardiac surgery.
- Conditions
- Hypotension, Postoperative Complications, Acute Coronary Syndrome, Heart Failure
- Trial name
- BBB (NCT02533128)
- Testing
- Liberal blood pressure management, Tight blood pressure management
- Where
- Switzerland
- Volunteers
- 458 people
- Sponsor
- Miodrag Filipovic, Prof. Dr. med.
Perioperative/Postoperative Complications, Morbidity, Multiple
Machine Learning Modeling of Intraoperative Hemodynamic Predictors of Postoperative Outcomes
With population aging and limited resources, strategies to improve outcomes after surgery are ever more important. There is a limited understanding of what ranges of hemodynamic variables under anesthesia are associated with…
- Conditions
- Perioperative/Postoperative Complications, Morbidity, Multiple, Surgery, Anesthesia
- Trial name
- NCT04014010
- Testing
- Blood pressure, Heart rate, Use of hemodynamic medications (i.e. special medications for blood pressure)
- Volunteers
- 35,000 people
- Sponsor
- Janny Xue Chen Ke
Sudden Cardiac Death, Ventricular Fibrillation
Prognostic Value of Ventricular Fibrillation Spectral Analysis in Sudden Cardiac Death
Ventricular fibrillation (VF)-related sudden cardiac death (SCD) is a leading cause of mortality. Patients may survive with neurological damage despite state-of-the-art treatment.
- Conditions
- Sudden Cardiac Death, Ventricular Fibrillation, Reperfusion Injury
- Trial name
- AWAKE (NCT03248557)
- Testing
- Spectral analysis of ventricular fibrillation tracings
- Where
- 5 sites in Spain
- Volunteers
- 168 people
- Sponsor
- Hospital San Carlos, Madrid
Myocardial Infarction Postoperative, Myocardial Injury
Preoperative BNP: Epidemiological Patterns, Management Strategies and Cost Analysis of Care
Recently, the use of preoperative BNP as a preoperative risk stratifcation tool was added to the Canadian Cardiovascular Society (CCS) guidelines (4) on perioperative cardiac risk assessment and management for patients who…
- Conditions
- Myocardial Infarction Postoperative, Myocardial Injury, Death, Cardiac
- Trial name
- NCT04077294
- Testing
- Cardiac risk stratification using preoperative BNP measurement, followed by postoperative cardiac monitoring, Use of traditional perioperative cardiac risk stratification only
- Where
- Canada
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Noncardiac Surgery, Postoperative Myocardial Infarction
The Prognostic Capabilities Of A Preoperative Six-Minute Walk Test To Independently Inform Cardiovascular Risk After Major Noncardiac Surgery
This prospective cohort study aims to determine whether the addition of the 6MWT to the RCRI score improves the risk prediction of postoperative cardiovascular outcomes after noncardiac surgery.
- Conditions
- Noncardiac Surgery, Postoperative Myocardial Infarction, Postoperative Death, Risk Assessment
- Trial name
- NCT02860754
- Testing
- Six-minute walk test to perform before surgery
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Kidney Disease, Liver Disease
Remote Ischemic Preconditioning In Abdominal Organ Transplantation
Does remote ischemic preconditioning (RIPC) induced by a brief period of occlusion of blood flow to the lower extremity prior to organ recovery in deceased donors, improve short and long term outcomes after transplantation of…
- Conditions
- Kidney Disease, Liver Disease, Pancreas Disease
- Trial name
- RIPCOT (NCT00975702)
- Testing
- RIPC by Inflation of Pneumatic Tourniquet
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Surgery, Death
Risk Calculators Validation for Elective Major General Surgery
Nowadays, over 300 million surgical operations take place every year worldwide, which increase at a rate of 33.6% comparing data from 2005 to 2013.
- Trial name
- RCVEMG (NCT04041076)
- Testing
- Major surgical operation
- Where
- Hong Kong
- Volunteers
- 5,000 people
- Sponsor
- Chinese University of Hong Kong
Type 1 Diabetes, Insulin-requiring Type 2 Diabetes Mellitus
Use of Closed Loop Insulin Delivery for Glucose Control in Patients With Insulin Dependent Diabetes Mellitus After Kidney Transplantation
This study will be a prospective, single center, randomized controlled parallel group open-label trial. Participants with insulin requiring diabetes mellitus who have been offered an organ for living or deceased donor kidney…
- Conditions
- Type 1 Diabetes, Insulin-requiring Type 2 Diabetes Mellitus, End Stage Renal Disease (ESRD)
- Trial name
- NCT04189510
- Testing
- Artificial Pancreas, Multiple Daily Injections
- Sponsor
- University of Virginia
End Stage Chronic Renal Failure, Chronic Kidney Disease (Stages 4 and 5)
Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage
The goal of this clinical trial is to test how storage temperature of deceased donor kidneys affects kidney function after transplant in adult patients receiving a kidney transplant.
- Conditions
- End Stage Chronic Renal Failure, Chronic Kidney Disease (Stages 4 and 5), Kidney Transplantation Recipients
- Trial name
- NCT07385651
- Testing
- 10˚C deceased donor kidney storage using Traferox XPort
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Survival Myocardial Area After Acute Myocardial Death, Left Ventricular Ejection Fraction
Clinical Study of Cardiomyopeptidin on Postoperative Ischemia-reperfusion Injury in Patients With Primary PCI
In this study, advanced techniques of myocardial nuclear magnetic perfusion scanning were used to quantitatively assess infarct size after acute myocardial infarction, saved viable myocardium, and microcirculatory obstruction…
- Trial name
- NCT03958422
- Testing
- cardiomyopeptidin
- Volunteers
- 160 people
- Sponsor
- Dalian Zhen-Ao Bio-Tech Co., Ltd.
Electrolyte Imbalance, Kidney Transplant; Complications
The Comparison Between Ringer Lactate Solution and Normal Saline With Dextrose Water in Post-Operative Period of Kidney Transplantation
This is a randomized controlled pragmatic clinical trial. We aim to evaluate the effect of Ringer lactate solution (RLS) and normal saline solution (NSS) with dextrose water (D5W) on the electrolyte abnormality of kidney…
- Trial name
- RINNOR (NCT06030609)
- Testing
- Ringer's Lactate Crystalloid Solutions, Normal saline
- Where
- Thailand
- Volunteers
- 159 people
- Sponsor
- King Chulalongkorn Memorial Hospital