Clinical trials: Postoperative Nausea and Vomiting (PONV)
Postoperative Nausea and Vomiting
Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery
Postoperative pain, the great concern for the patients undergoing spine surgery, has led to common use of opioid-based intravenous patient-controlled analgesia (IV-PCA) postoperatively.
- Trial name
- NCT01825733
- Testing
- ramosetron, palonosetron
- Volunteers
- 196 people
- Sponsor
- Yonsei University
Menstrual Cycle, Optic Nerve Sheath Diameter
Effects of Menstrual Cycle on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery
This observational study aims to evaluate the effect of menstrual cycle phase on optic nerve sheath diameter (ONSD) in women undergoing elective laparoscopic gynecologic surgery.
- Conditions
- Menstrual Cycle, Optic Nerve Sheath Diameter, Postoperative Nausea and Vomiting
- Trial name
- NCT07539831
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital
Anesthesia, Cancer
Evaluation of Pain and Postoperative Nausea Vomiting Incidence in Outpatient Surgery at IUCT-Oncopole Hospital
The effectiveness of the analgesic and anti-nausea prevention techniques of the investigators justifies being evaluated regularly in order to adapt the management strategy to the specificities of each surgical act.
- Conditions
- Anesthesia, Cancer, Surgery
- Trial name
- NCT03669328
- Testing
- locoregional anesthesia
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Institut Claudius Regaud
Postoperative Nausea and Vomiting
Effect of Lavender Aromatherapy on Post-Operative Nausea and Vomiting Among Laparotomy Patients
Post-operative nausea and vomiting are critical problems that occur commonly after the administration of general anesthesia, which can lead to serious health complications such as hemorrhage, electrolyte imbalance and ultimate…
- Trial name
- NCT06060418
- Testing
- aromtherapy
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- University of Health Sciences Lahore
Postoperative Nausea and Vomiting
Risk Factors for Nausea and Vomiting After Cesarean
Investigators will observe the incidence of post-cesarean nausea or vomiting and try to associate it with some risk factors.
- Trial name
- NCT03171688
- Where
- Brazil
- Volunteers
- 361 people
- Sponsor
- Brasilia University Hospital
Nausea and Vomiting
A Clinical Study to Evaluate Cyclopofol Injection for the Prevention of Postoperative Nausea and Vomiting
This study uses cyclopropofol as a positive control and adopts a large sample, multicenter, randomized, single-blind, positive parallel control test design to explore the clinical application value of cyclopropofol in preventing…
- Trial name
- NCT05837156
- Testing
- Heptaflurane combined Cyclophenol, Heptaflurane, Cyclophenol
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Mengchang Yang
Postoperative Nausea and Vomiting, Bowel Functions
Menthol Chewing Gum After Laparoscopic Colorectal Surgery
This randomized controlled trial was conducted to evaluate the effect of menthol chewing gum on postoperative nausea and vomiting, bowel function, and recovery in patients undergoing laparoscopic colorectal surgery.
- Conditions
- Postoperative Nausea and Vomiting, Bowel Functions, Postoperative Recovery
- Trial name
- NCT07796529
- Testing
- Menthol Chewing Gum
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sennur Kula Şahin
Penehyclidine, Postoperative Nausea and Vomiting
Penehyclidine for Prevention of Nausea and Vomiting After Bimaxillary Surgery
Postoperative nausea and vomiting (PONV) is a common complication after surgery. Patients undergoing orthognathic surgery are reported to have a high rate of PONV, especially those undergoing bimaxillary surgery.
- Conditions
- Penehyclidine, Postoperative Nausea and Vomiting, Bimaxillar Surgery
- Trial name
- NCT04454866
- Testing
- Single injection of penehyclidine, Continuous infusion of penehyclidine
- Where
- China
- Volunteers
- 354 people
- Sponsor
- Peking University First Hospital
Postoperative Nausea and Vomiting
Aprepitant for Postoperative Nausea and Vomiting in Laparoscopic Hysterectomy
Gynecological surgery is associated with a high incidence of postoperative nausea and vomiting. NK1 receptor antagonists such as aprepitant appear to be highly effective for treating acute and delayed emesis, and yet…
- Trial name
- NCT01440673
- Testing
- Aprepitant
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Gachon University Gil Medical Center
Postoperative Nausea and Vomiting
A Study of Vestipitant (GW597599) in the Treatment of Breakthrough Postoperative Nausea and Vomiting (PONV)
This study will evaluate single IV doses of Vestipitant (GW597599) compared to 4 mg IV ondansetron for treating breakthrough postoperative nausea and vomiting (PONV) after failure of PONV prophylaxis with a regimen that includes…
- Trial name
- NCT01507194
- Testing
- Ondansetron, Vestipitant
- Where
- 7 sites in United States
- Volunteers
- 131 people
- Sponsor
- Accenture
Postoperative Nausea and Vomiting
The Effects of Gabapentin and Ramosetron on Postoperative Nausea and Vomiting in Laparoscopic Gynecological Surgery
This study was designed to compare the effects of gabapentin and ramosetron on PONV in patients undergoing laparoscopic gynecologic surgery.
- Trial name
- PONV (NCT02617121)
- Testing
- Gabapentin, Ramosetron, Gabapentin and Ramosetron
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hallym University Medical Center
Postoperative Nausea and Vomiting
Safety of Preoperative Oral Administration of a High Caloric Drink With Protein
The purpose of the study is to determine whether the oral administration of a high caloric drink with protein decreases the postoperative nausea and vomiting in patients with dysgnathia.
- Trial name
- NCT00151099
- Testing
- high caloric drink with protein
- Where
- Germany
- Sponsor
- University Hospital Muenster
Postoperative Nausea and Vomiting, Respiratory Conditions Due to Other External Agents
A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery
The investigators will track bariatric patients who received sugammadex versus neostigmine in the post anesthesia care unit until discharge and assess their length of stay and possible nausea / vomiting / hypoxia episodes.
- Trial name
- NCT03276026
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Postoperative Nausea, Postoperative Vomiting
The Impact of Nasogastric Tube Gastric Decompression on Postoperative Nausea and Vomiting in Orthognathic Surgery
This study will compare the incidence of postoperative nausea and vomiting during the first 24 hours following corrective jaw surgery (orthognathic surgery) in patients with and without nasogastric tube gastric decompression.
- Trial name
- NCT06422793
- Testing
- No NG tube gastric decompression
- Where
- Canada
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Nausea and Vomiting, Postoperative
An Economic Study of HSK21542 Injection for Prevention of Postoperative Nausea and Vomiting
This study analyzed the efficacy and safety results of HSK21542 injection for the prevention of postoperative nausea and vomiting in a multicentre, randomized, double-blind, placebo-controlled dose-exploration study, as well as…
- Trial name
- NCT06359535
- Testing
- HSK21542
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Mengchang Yang
Postoperative Nausea and Vomiting
Comparison of Three Different Prophylactic Treatments of Postoperative Nausea and Vomiting (PONV) in Children
Incidence of postoperative nausea and vomiting (PONV) in children after tonsillectomy with or without adenoidectomy may be as high as 75%.
- Trial name
- NCT01434017
- Testing
- Dexamethasone, Dexamethasone and droperidol, Dexamethasone and Ondansetron
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Postoperative Nausea and Vomiting, Hysterectomy
Effect of SmtO2 Guided Care on PONV (iMODIPONV)
This randomized controlled trial is to investigate if SmtO2-guided management on top of the usual care, compared with the usual care only, during laparoscopic hysterectomy significantly reduces the incidence of PONV.
- Conditions
- Postoperative Nausea and Vomiting, Hysterectomy, Tissue Oxygenation, Cardiac Output Management
- Trial name
- iMODIPONV (NCT03641625)
- Testing
- Muscular tissue oxygen saturation guided care
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Yale University
Gynecologic Disease
Opioid-free Anesthesia in Gynecologic Surgery
Post-operative nausea and vomiting (PONV) is common for the patients undergoing laparoscopic gynecologic surgery. PONV is a major factor for patient dissatisfaction, delayed patient recovery and increased medical expenses.
- Trial name
- NCT04700761
- Testing
- Opioid-free anesthesia, Opioid-using anesthesia
- Where
- South Korea
- Volunteers
- 164 people
- Sponsor
- Seoul National University Bundang Hospital
Anesthesia
Evaluation of Regional Blocks Efficacy in Orthognathic Surgery
The proposed study, which will be carried out on 72 male and female patients, who have reached bone maturity, are younger than 50 years and underwent orthognathic surgical procedures.
- Trial name
- NCT07133048
- Testing
- Levobupivakain 0.25 %, NaCl 0.9 %
- Where
- Croatia
- Volunteers
- 72 people
- Sponsor
- Clinical Hospital Center Rijeka
Surgery
The Effect of Oral Carbohydrate Inhalation Given to Patients Before Coronary Artery Bypass Graft Operation on Recovery
The aim of this study was to investigate the effect of oral carbohydrate solution given to patients before coronary artery bypass graft surgery on nausea-vomiting, hunger, thirst, physiologic parameters and recovery.
- Trial name
- NCT06788951
- Testing
- administration of oral carbohydrate solution to patients before coronary artery bypass graft surgery, giving flavored water to patients before coronary artery bypass graft surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yasemin Bozkurt