Clinical trials: Postoperative Pain Following Hysterectomy
Postoperative Pain, Hysterectomy
Comparison of Butorphanol and Tramadol Associated Patient-Controlled Analgesia (PCA) After Hysterectomy
Intravenous patient-controlled analgesia (PCA) is a popular technique for postoperative pain management. Although several drugs are recognized as effective therapeutic options, optimal selection of drugs in hysterectomy patients…
- Trial name
- BATPCAH (NCT00510666)
- Testing
- Saline, Butorphanol tartrate, Tramadol Hydrochloride
- Where
- China
- Volunteers
- 841 people
- Sponsor
- Nanjing Medical University
Abdominal Hysterectomy
Effect of Intrathecal Magnesium Sulfate Versus Intravenous Magnesium Sulfate on Postoperative Pain After Abdominal Hysterectomy
The present study aims to compare the effect of adding IV magnesium sulfate versus magnesium sulfate to intrathecal hyperbaric bupivacaine in total abdominal hysterectomy regarding the duration of postoperative analgesia…
- Trial name
- NCT06367595
- Testing
- Magnesium sulfate
- Volunteers
- 90 people
- Sponsor
- Assiut University
Pain
Bupivacaine Injections Into Uterosacral Ligaments During Robotic Assisted Total Hysterectomies
Will patients that receive injections of Marcaine into the uterine nerve via the uterosacral ligaments experience less pain postoperatively, need less narcotic pain medication and return to activities of daily living sooner.
- Trial name
- NCT02230735
- Testing
- Bipivacaine 0.5% with epinephrine, Normal Saline
- Where
- United States
- Sponsor
- Souza, Amanda, M.D.
Pain Postoperative
Analgesic Efficacy of Transmuscular Quadratus Lumborum in Patients Undergoing Total Abdominal Hysterectomy
Patients who have undergone laparotomies often require multimodal postoperative pain regimes. In recent years, abdominal wall blocks have been included to become part of this in order to overcome side effects of systemic opioids…
- Trial name
- NCT02586454
- Testing
- Transmuscular quadratus lumborum block, morphine, ropivacaine
- Where
- Malaysia
- Volunteers
- 64 people
- Sponsor
- Kuala Lumpur General Hospital
Pain Intensity
Intraoperative Intravenous Lidocaine
The objective of the present study was to evaluate the effect of intraoperative intravenous lidocaine on postoperative pain after hysterectomy.
- Trial name
- NCT00965796
- Testing
- Lidocaine
- Where
- 2 sites in Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Hysterectomy
Quadratus Lumborum Block Versus Dual Transversus Abdominis Plane and Ilioinguinal/Iliohypogastric Nerve Blocks for Postoperative Analgesia Following Total Abdominal Hysterectomy
Multimodal pain management program is needed to control severe pain after abdominal hysterectomy which is considered as one of the major abdominal surgeries.
- Trial name
- NCT04382274
- Testing
- Quadratus Lumborum Block, Dual Transversus Abdominis Plane and Ilioinguinal/Iliohypogastric Nerve blocks
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Pain, Postoperative
Injection of Local Anesthetic to Trocar Insertion Sites After Laparoscopy
The primary objective of this study is to assess if injection of local anesthetic to the laparoscopic trocar sites after a hysterectomy will make a difference in a patient's pain after surgery.
- Trial name
- NCT01688596
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Milton S. Hershey Medical Center
Postoperative Analgesia
Epidural Versus Continuous Wound Ropivacaine Infusion Analgesia
Study Hypothesis: The analgesic requirements and pain scores postoperatively differ between the epidural and continuous wound infusion techniques.
- Trial name
- NCT01916473
- Testing
- Epidural analgesia, Continuous wound infusion
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- University of Athens
Pain, Postoperative
Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy
Hysterectomy is the most common major gynecologic surgery performed in the US and is performed for a variety of indications including malignancy, pelvic mass, endometriosis, leiomyoma, and pelvic organ prolapse.
- Trial name
- RA-TLH (NCT04429022)
- Testing
- Gabapentin, Acetaminophen, Celecoxib
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Acute Pain
Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery
The purpose of this study is to determine the effectiveness and safety of single intravenous doses of the kappa opioid agonist CR845 in relieving pain in patients following laparoscopic-assisted hysterectomy surgery.
- Trial name
- NCT00877799
- Testing
- CR845
- Where
- 12 sites in United States
- Volunteers
- 114 people
- Sponsor
- Cara Therapeutics, Inc.
Postoperative Pain
Efficacy and Safety of a Collagen Bupivacaine Implant in Women Following Abdominal Hysterectomy
The purpose of this study is to determine whether the CollaRx Bupivacaine implant is safe and effective in reducing the amount of narcotic pain medication needed to control pain during the first 24 hours after abdominal…
- Trial name
- NCT00624910
- Testing
- Bupivacaine Collagen Sponge (CollaRx®)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Innocoll
Postoperative Pain
Bupivacaine for Postoperative Pain After Laparoscopic Hysterectomy
This prospective, randomized, single-blind controlled study aims to evaluate the effect of bupivacaine injection at trocar entry sites and the vaginal cuff on postoperative pain in patients undergoing total laparoscopic…
- Trial name
- bupivacaine (NCT07435909)
- Testing
- Bupivacaine %0.5 (hyperbaric)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Serkan Kumbasar
Postoperative Pain, Abdominal Hysterectomy
Effect of Different Volumes of Erector Spinae Plane Block on Postoperative Opioid Consumption After Total Abdominal Hysterectomy
his study aims to investigate the effects of different volumes of ultrasound-guided erector spinae plane block (ESPB) on postoperative pain and opioid consumption in patients undergoing total abdominal hysterectomy.
- Conditions
- Postoperative Pain, Abdominal Hysterectomy, Pain
- Trial name
- NCT07533760
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Şule Arıcan
Postoperative Pain Following Hysterectomy
TAP Block With Lidocaine and Ropivacaine 0.2% (0.4 ml/kg/Side) for Pain and Opioid Reduction After Hysterectomy
The goal of this study is to evaluate whether the Transversus Abdominis Plane (TAP) block can effectively reduce postoperative pain and opioid consumption in patients undergoing elective hysterectomy.
- Trial name
- TAP (NCT07139691)
- Testing
- Pre-incisional Transversus Abdominis Plane (TAP) block performed under ultrasound guidance. The block will be administered bilaterally using a mixture of lidocaine and ropivacaine 0.2%, Participants in this arm will receive standard analgesia for postoperative pain management following elective hysterectomy
- Where
- Romania
- Volunteers
- 82 people
- Sponsor
- Matild Keresztes
Hysterectomy, Genital Diseases, Female
Follow-up Strategies for Improved Postoperative Recovery After Benign Hysterectomy
The purpose of the study is to investigate the effect of four different follow-up strategies on postoperative recovery following vaginal or abdominal hysterectomy for benign conditions.
- Conditions
- Hysterectomy, Genital Diseases, Female, Pain
- Trial name
- POSTHYSTREC (NCT01526668)
- Testing
- Follow-up strategy, No contact after discharge
- Where
- 5 sites in Sweden
- Volunteers
- 525 people
- Sponsor
- University Hospital, Linkoeping
Uterine Disease, Postoperative Pain
Postoperative Pain After Total Laparoscopic Hysterectomy: a Comparison of Single-port and Three-port Laparoscopy
The objective of this study is to compare postoperative pain between single-port access total laparoscopic hysterectomy (SPA-TLH) using a transumbilical single-port system and conventional multi (three)-port access total…
- Trial name
- NCT02390804
- Testing
- single-port laparoscopic hysterectomy(single port trochar), multi-port laparoscopic hysterectomy(multi port trochar)
- Volunteers
- 60 people
- Sponsor
- The Catholic University of Korea
Uterine Bleeding, Uterine Neoplasms
Anterior Quadratus Lumborum Block as a Component of Multimodal Analgesia for Abdominal Hysterectomies
The main goal of this randomised double-blinded controlled trial is to assess whether adding anterior quadratus lumborum block preoperatively can reduce intraoperative and postoperative opioid consumption, reduce pain after…
- Conditions
- Uterine Bleeding, Uterine Neoplasms, Uterine Diseases, Uterine Fibroids
- Trial name
- NCT07046949
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, Parenteral administration of analgesics, General Anesthesia (GA)
- Where
- Ukraine
- Volunteers
- 56 people
- Sponsor
- Yuri Semenyuk Rivne Regional Clinical Hospital
Post Operative Pain
Effect of Pregabalin on Post Operative Pain in Abdominal Hysterectomy Under Spinal Anesthesia With Intrathecal Morphine
This study aims to compare the effect of pre-operative oral pregabalin on post operative morphine consumption after abdominal hysterectomy with/without salpingo-oophorectomy.
- Trial name
- NCT02285010
- Testing
- Pregabalin
- Where
- Thailand
- Volunteers
- 125 people
- Sponsor
- Mahidol University
Postoperative Pain, vNOTES
Does Intraperitoneal Washout Further Reduce Pain After Low-Pressure vNOTES Hysterectomy?
The evolution of minimally invasive gynecology has transitioned from traditional laparotomy to laparoscopy, and most recently, to vNOTES (Vaginal Natural Orifice Transluminal Endoscopic Surgery).
- Trial name
- Low-Pressure (NCT07467577)
- Testing
- warm saline
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Pain, Postoperative, Pain Uterus
Effects of Tapentadol Versus Oxycodone After Hysterectomy.
Opioids remain the first-line drugs for the treatment of moderate to severe postoperative pain, but the use is limited by well-known side-effects, most of which are dose-dependent.
- Conditions
- Pain, Postoperative, Pain Uterus, Pain, Acute, Opioid Use
- Trial name
- NCT03314792
- Testing
- Tapentadol, Oxycodone
- Where
- Norway
- Volunteers
- 86 people
- Sponsor
- Oslo University Hospital