Clinical trials: Postoperative Pain Following Hysterectomy
Laparoscopic Hysterectomy
Post Operative Pain After Laparoscopic Hysterectomy Using Airseal® Versus Standard Insufflation System
Airseal® is an insufflation management system for laparoscopic surgery which provides stable pneumoperitoneum, continuous smoke evacuation and valve-free access to the abdominal cavity.
- Trial name
- AIRSEAL (NCT03418402)
- Testing
- Airseal®, Standard insufflator
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Postoperative Pain
An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Undergoing Hysterectomy
The objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing hysterectomy on the basis of pharmacokinetics, efficacy and safety evaluations.
- Trial name
- NCT00993226
- Testing
- SABER-Bupivacaine Treatment 1a, Bupivacaine HCl Treatment 1c, SABER-Bupivacaine Treatment 2a
- Where
- 14 sites in France, Germany and 4 more
- Volunteers
- 115 people
- Sponsor
- Durect
Postoperative Pain
Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy
This is a randomized, double-blinded, placebo-controlled trial to compare the effectiveness of IV oxytocin infusion to placebo on peri-operative opioid consumption and reducing post-operative pain following a minimally invasive…
- Trial name
- NCT06483659
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Post Operative Analgesia
Erector Spinae Plane Versus Quadratus Lumborum Blocks for Pain Management After Total Abdominal Hysterectomy
TAH, being a large scale gynaecological operation, is a construction bound to cause serious postoperative pain to the patient in that the procedure will inevitably entail massive tissue dissection.
- Trial name
- NCT07480499
- Testing
- Erector Spinae Plane Block, Quadratus Lumborum Block (QLB)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Chronic Pain, Acute Pain, Cotinine, Hysterectomy
The Correlation Between Cotinine and Postoperative Acute and Chronic Pain After Hysterectomy
It is known that there is an association between smoking and acute/chronic pain. But it is so difficult to assess this relation with asking questions to the patients in the preoperative period.
- Trial name
- NCT04274673
- Testing
- measuring cotinine level
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people
- Sponsor
- Mustafa Kemal University
Hysterectomy, Myoma
Morphine vs. Oxycodone for Postoperative Pain Management
The purpose of this study is to determine whether oxycodone provides better analgesia compared to morphine after laparoscopic hysterectomy or myomectomy.
- Conditions
- Hysterectomy, Myoma, Postoperative Pain, Opioids
- Trial name
- NCT00528177
- Testing
- Morphine and oxycodone
- Where
- Norway
- Volunteers
- 90 people
- Sponsor
- Ullevaal University Hospital
Post-operative Pain Management
TAP Block , Intrathecal Morphine Or Their Combination For Post Operative Analgesia Following TAH
This randomized controlled clinical trial designed to evaluate the efficacy of transversus abdominis plane (TAP) block, intrathecal morphine, or their combination in postoperative pain relief, as assessed by time to first…
- Trial name
- NCT06882369
- Testing
- TAP Block, Intrathecal morphine injection, spinal anesthesia
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Minia University
Post Operative Analgesia
Intravenous Ibuprofen Postoperative Analgesia After Abdominal Hysterectomy
The current research is designed to investigate the analgesic efficacy of intravenous ibuprofen on the postoperative analgesic requirements, pain intensity and other recovery parameters.
- Trial name
- NCT05750264
- Testing
- Ibuprofen
- Where
- Egypt
- Volunteers
- 152 people
- Sponsor
- Menoufia University
Postoperative Pain
Bilateral Erector Spinal Plan Block in Postoperative Analgesia After Total Abdominal Hysterectomy
The importance of effective postoperative pain management is well known. Overall, for total abdominal hysterectomy operations are related with severe postoperative pain.
- Trial name
- NCT05513196
- Testing
- Erector spinae plane block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Kocaeli University
Post Operative Pain
Effect of Different Plane Blocks on Quality of Recovery and Postoperative Pain After Laparoscopic Hysterectomy
The goal of this clinical trial is to evaluate in effect of tap block and esp block on quality of recovery and postoperative pain after laparoscopic hysterectomy.
- Trial name
- NCT05780333
- Testing
- TAP block, ESP block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mentese State Hospital
Pain, Postoperative
Intraperitoneal Lavage for Reducing Pain in Laparoscopy
The aim of the present study is to evaluate the role of intraperitoneal washing irrigation with saline solution at the end of laparoscopic hysterectomy or myomectomy in reducing perception of postoperative pain.
- Trial name
- NCT03290521
- Testing
- intraperitoneal washing with saline solution, No washing
- Where
- Italy
- Volunteers
- 277 people
- Sponsor
- Campus Bio-Medico University
Hysterectomy, Myomectomy
Effect of Perioperative iv Dexmedetomidine vs. Lidocaine on Postoperative Pain, Analgesic Consumption and Recovery After Abdominal Gynaecological Surgery
Postoperative pain continues to be inadequately managed and is the most common reason for the delay in discharge and unplanned hospital admission after surgery. Opioids remain the mainstay for postoperative analgesia.
- Trial name
- NCT03363425
- Testing
- Lidocaine Iv, Dexmedetomidine, Normal saline
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Athens
Acute Pain
Oral Treatment for Gynaecological Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride
This study aims to evaluate the analgesic efficacy of single and repeated doses of fixed combination of dexketoprofen trometamol (DKP) and tramadol hydrochloride (TRAM) in comparison to the single agents (and placebo for the…
- Trial name
- DAVID lap (NCT01904149)
- Testing
- Dexketoprofen-single dose, Tramadol-single dose, Dexketoprofen/Tramadol-single dose
- Where
- 28 sites in Hungary, Latvia and 6 more
- Volunteers
- 606 people
- Sponsor
- Menarini Group
Pain, Postoperative
The Effect of Pre-sacral Nerve Block on Immediate Post-operative Pain Following Laparoscopic Hysterectomy.
Hysterectomy (removal of the uterus) is the most common major gynecologic surgery performed in Canada. With a focus on minimally invasive techniques and optimization of peri-operative pain control, gynaecologists have made great…
- Trial name
- NCT03646006
- Testing
- Bupivacaine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Mount Sinai Hospital, Canada
Post Operative Pain, Shoulder Pain
The Effect of Postoperative Modified Trendelenburg Position to Decrease Shoulder Pain After Laparoscopic Hysterectomy: A Randomized Controlled Trial
Laparoscopic surgery is commonly used procedure in diagnostic and treatment including Hysterectomy. Post laparoscopic shoulder pain is common side effect mostly occur after surgery.
- Conditions
- Post Operative Pain, Shoulder Pain, Gynecologic Disease
- Trial name
- NCT05428982
- Testing
- Postoperative Modified Trendelenburg position
- Where
- Thailand
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Pain, Postoperative, Postoperative Nausea and Vomiting
Trigonelline Plus Sufentanil for Postoperative Analgesia After Laparoscopic Hysterectomy: A Randomized Controlled Clinical Trial
The goal of this clinical trial is to learn whether the combination of trigonelline and sufentanil can better control postoperative pain in adult women undergoing gynecologic laparoscopic surgery, while reducing discomforts such…
- Trial name
- TPS-GLS (NCT07914946)
- Testing
- Sufentanil, Trigonelline
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Hainan Medical College
Hysterectomy
Randomized Controlled Trial Comparing Postoperative Pain Following TAH With GA vs. Combined GA + SAB
The investigators hypothesize that a spinal anesthetic administered prior to the induction of general anesthesia will result in reduced need for pain medication and reduced postoperative pain, as well as reduced hospital stay…
- Trial name
- NCT01511627
- Testing
- General Anesthesia + Spinal anesthesia combined, General Anesthesia (control group)
- Where
- Canada
- Sponsor
- University of Saskatchewan
Opioid Use, Surgical Recovery
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
The goal of the study to see if giving a numbing medicine around the cervix (called a paracervical block) during vaginal hysterectomy with prolapse repair helps people feel less pain and need fewer strong pain medicines…
- Conditions
- Opioid Use, Surgical Recovery, Vaginal Hysterectomy, Prolapse Pelvic
- Trial name
- NCT07213635
- Testing
- Bupivacaine-epinephrine, Normal saline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Post Hysterectomy Pain
Ultrasound Guided QLB Versus Laparoscopic Superior Hypogastric Plexus Block for Postoperative Analgesia After Laparoscopic Hysterectomy
Pain following laparoscopic hysterectomy may interfere with early ambulation, discharge of patient from hospital and interfere with enhanced recovery with more opioid consumption.
- Trial name
- NCT06359743
- Testing
- Quadratus Lamborum versus superior hypogatric
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Zagazig University
Pain, Postoperative
Comparison of Adverse Drug Reactions Associated for Oxycodone and Morphine in Postoperative Pain After Abdominal Hysterectomy
The objective of this study is compare adverse reactions associated with oxycodone and morphine for the treatment of postoperative pain after abdominal hysterectomy
- Trial name
- NCT02936934
- Testing
- Morphine, Oxycodone
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hospital Civil de Guadalajara