Clinical trials: Postoperative Pain Management, After VATS
Thoracic Surgery, Video-assisted, Postoperative Pain
RCT Comparing Analgesia Post-VATS With Epimorph VS Placebo
The purpose of the study is to determine if the administration of a mix of Sufentanil and Morphine in intrathecal is a better analgesia regimen than PCA alone in patient post-VATS.
- Conditions
- Thoracic Surgery, Video-assisted, Postoperative Pain, Rachianesthesia, Sufentanil
- Trial name
- NCT02152514
- Testing
- Intrathecal Morphine/Sufentanil, PCA
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Université de Sherbrooke
Pain, Postoperative
Thoracic Paravertebral Block for Postoperative Analgesia After Video-assisted Thoracic Surgery.
The use of paravertebral catheters is a recommended technique to achieve postoperative analgesia after thoracic surgery. To date there is no consensus on which drug regime (local anesthetics with or without opioid) is best.
- Trial name
- PARAVI (NCT01082744)
- Testing
- Ropivacaine + Sufentanil, Ropivacaine
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Hospices Civils de Lyon
Postoperative Pain Management
Ultrasound-Guided Erector Spinae Plane Block Versus Intravenous Nalbuphine
2.1. Study population and setting: This prospective, randomized, controlled clinical trial will be conducted at the thoracic surgery operation room, cardiothoracic surgery building, Zagazig University Hospitals, from July 2025 to…
- Trial name
- VATS (NCT07391475)
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Zagazig University
Nausea, Vomiting
Effect of Dexamethasone Combined With Ondansetron on Postoperative Nausea and Vomiting in Patients With Patient-controlled Analgesia After Video-assisted Thoracoscopic Surgery
The purpose of this study is to study the effect of dexamethasone combined with ondansetron on postoperative nausea and vomiting in patients with patient-controlled analgesia after video-assisted thoracoscopic surgery.
- Trial name
- NCT01007500
- Testing
- Dexamethasone, Ondansetron
- Where
- South Korea
- Volunteers
- 123 people
- Sponsor
- Yonsei University
Thoracic Surgery, Video-Assisted
Erector Spinae Plane Block For Analgesia Following Video-Assisted Thoracoscopic Surgery
Erector spinae (ESP) block is a recently described plane block designed to block the dorsal and ventral rami of the thoracic spinal nerves. It is meant to block the ipsilateral trunk.
- Trial name
- NCT03860480
- Testing
- ESP with Bupivacaine 0.5%, ESP with Saline 0.9%
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Intercostal Nerve Block, Serratus Posterior Superior Intercostal Plane Block
Analgesic Efficiency of SIPSPB vs ICNB in VATS Surgery
This study aims to evaluate the effectiveness of Serratus Posterior Superior Intercostal Plane (SPSIP) block compared to Intercostal Nerve (ICN) block in terms of postoperative pain control, reduction of opioid analgesic…
- Conditions
- Intercostal Nerve Block, Serratus Posterior Superior Intercostal Plane Block, Post-operative Pain Management, VATS
- Trial name
- NCT07577908
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kocaeli City Hospital
Post-operative Analgesia, Retrolaminar Block
Comparison Between Erector Spinae Plane Block And Retrolaminar Block In Patients Undergoing VATS.
Post-Video-assisted thoracoscopic surgery pain is a challenging clinical problem that may be associated with increased morbidity and mortality.
- Conditions
- Post-operative Analgesia, Retrolaminar Block, Erector Spinae Plan Block, VATS
- Trial name
- NCT06021327
- Testing
- Erector spinae plane block, Retrolaminar block
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Uniportal-VATS, Lung Resection Procedures
Serratus Posterior Superior Intercostal Plane (SPSIP) Block Versus Intercostal Nerve (ICN) Block in Patients Undergoing Uniportal-VATS.
This study aims to assess the effectiveness of the Serratus Posterior Superior Intercostal Plane (SPSIP) block compared to the Intercostal Nerve (ICN) block for postoperative pain control, reduction of opioid analgesic…
- Conditions
- Uniportal-VATS, Lung Resection Procedures, Locoregional Anesthesia, Post-operative Pain Management
- Trial name
- SPUV (NCT07250373)
- Testing
- SPSIP block, ICN block
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Postoperative Pain
Erector Spinae Plane Block vs Retrolaminar Block for Analgesia After VATS
This study compared the postoperative analgesic efficacy of ultrasound-guided erector spinae plane (ESP) block and retrolaminar block in patients undergoing video-assisted thoracoscopic surgery (VATS).
- Trial name
- NCT07830290
- Testing
- Erector spinae plane block (ESP), Retrolaminar block group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Hacettepe University
Thoracic Surgery, Video-Assisted
Intercostal Cryoanalgesia for Acute Pain After VATS Lung Resection
Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia as an adjunct to a single-injection…
- Conditions
- Thoracic Surgery, Video-Assisted, Cryotherapy Effect, Paravertebral Block
- Trial name
- CRYO-VATS (NCT05896150)
- Testing
- Cryoanalgesia AND single-injection paravertebral block, Single-injection paravertebral block
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lung Neoplasms, Postoperative Pain
Prospective Randomized Trial Comparing the Effectiveness of Continuous Paravertebral Infusion of Local Anesthetics Versus Intravenous Patient-controlled Analgesia on Acute and Chronic Neuropathic Pain After VATS Lobectomy
Since mid-2000, thoracoscopic lobectomy has been replaced with conventional open lobectomy and it has reduced the operative morbidities and mortalities.
- Trial name
- NCT01703351
- Testing
- 0.5% ropivacaine, Fentanyl 500mcg + acupan 160mg + nasea 0.6mg
- Where
- South Korea
- Volunteers
- 79 people
- Sponsor
- Yonsei University
Pain Management
Intrapleural Bupivacaine Analgesia for Postoperative Pain Management After Minimally Invasive Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial
Postoperative pain is common after video-assisted thoracoscopic surgery (VATS), with pleural irritation caused by chest tube placement being a major contributor.
- Trial name
- IBVATS (NCT07393386)
- Testing
- Bupivacaine 0.125%, Bupivacaine 0.25%, Normal Saline
- Where
- China
- Volunteers
- 249 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Pericardial Effusion, Inflammatory Response After Surgery
Anesthesia Management, Inflammatory Response and Recovery After Non-intubated VATS Pericardial Window
Non-intubated video-assisted thoracoscopic surgery (NIVATS) is performed under spontaneous ventilation and avoids tracheal intubation and one-lung mechanical ventilation.
- Conditions
- Pericardial Effusion, Inflammatory Response After Surgery, Postoperative Complications, Procedural Sedation and Analgesia
- Trial name
- RNIVATS (NCT07800767)
- Testing
- Systemic opioid-based analgesia during NIVATS, Thoracic regional analgesia during NIVATS
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Post Operative Pain
Post-Operative Kinesio Taping Impact on Pain in Thoracotomy vs Thoracoscopy
The project is of a comparative nature. It seeks to study pain reduction following two forms of chest surgery and compare results between both procedures. It will use kinesio taping as the studied pain reducer.
- Trial name
- NCT05200689
- Testing
- Kinesiotaping (KT)
- Where
- 5 sites in Egypt, Italy and 2 more
- Volunteers
- 310 people
- Sponsor
- Al-Quds University
Video-assisted Thoracoscopic Surgery
Patient-Controlled Thoracic Paravertebral Block After Video-Assisted Thoracoscopic Surgery
Thoracic surgery is commonly associated with severe postoperative pain and marked impairment of respiratory function.1 Minimally invasive video-assisted thoracic surgery (VATS) is assumed to result in better quality of life and…
- Trial name
- NCT02237664
- Testing
- Continuous paravertebral analgesia (C-PVB), Patient-controlled paravertebral analgesia (PC-PVB)
- Where
- Saudi Arabia
- Volunteers
- 62 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Video Assisted Thoracic Surgery (VATS)
Erector Spinae Plane Block Versus Serratus Anterior Plane Block in VATS
Pain control remains challenging in patients undergoing video-assisted thoracoscopic surgery (VATS). It is advised to use a regional block to lower postoperative opioid usage.
- Trial name
- VATS (NCT06996691)
- Testing
- Erector Spinae Plane Block (ESPB) group, Serratus Anterior Plane Block (SAPB) group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Lung Cancer, Pain
Two-Point Versus Single-Point Serratus Anterior Plane Block for Post-Thoracoscopic Surgery Analgesia
Postoperative pain remains a common clinical challenge in patients undergoing video-assisted thoracoscopic surgery (VATS), impairing early recovery and increasing opioid consumption.
- Conditions
- Lung Cancer, Pain, Video-Assisted Thoracoscopic Surgery, Serratus Anterior Plane Block
- Trial name
- NCT07700823
- Testing
- Two-Point Serratus Anterior Plane Block, Single-Point Serratus Anterior Plane Block
- Volunteers
- 88 people
- Sponsor
- Shiyou Wei
Analgesia, Post Operative Pain
Comparison of Midpoint Transverse Process to Pleura Block and Thoracic Paravertebral Block
In this study, hypothesis is that the MTPB (mid point transverse process block), which is easier and has fewer complications in patients aged 18-80 undergoing video-assisted thoracic surgery (VATS), provides analgesia as…
- Trial name
- NCT06089512
- Testing
- paravertebral block group, Mid point transverse process block group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Uludag University
Analgesia, Postoperative Pain
Ultrasound-Guided Serratus Anterior Plane Block in Pneumothorax Surgery
A prospective randomized controlled study was undertaken to compare the postoperative analgesic effect between ultrasound-guided serratus anterior plane block and intercostal nerve block after single port video-assisted…
- Conditions
- Analgesia, Postoperative Pain, Pneumothorax
- Trial name
- NCT04191850
- Testing
- Single Port Video-Assisted Thoracoscopic Surgery
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Kyungpook National University Hospital
Erector Spinae Muscle Plane Block, Serratus Anterior Muscle Plane Block
Analgesic Non Inferiority of the Thoracic Bi-block in Comparison With Thoracic Epidural for VATS.
Video-Assisted thoracic surgery (VATS) is the standard treatment for localized lung cancer. However, there is no consensus on analgesic management in patients undergoing VATS.
- Conditions
- Erector Spinae Muscle Plane Block, Serratus Anterior Muscle Plane Block, Video-Assisted Thoracic Surgery, Lung Cancer
- Trial name
- ANESSTEVATS (NCT04538235)
- Testing
- Thoracic Regional Analgesia
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier