Clinical trials: Postoperative Pain Management
Pain, Postoperative
Dexmedetomidine Versus Fentanyl on Postoperative Analgesic Profile in Laparoscopic Sleeve Gastrectomy
Dexmedetomidine (Dex) activates the α2 adrenergic receptor that is present within the locus coeruleus, leading to anxiolysis, hypnosis, analgesia, and sedation.
- Trial name
- NCT06186895
- Testing
- Dexmedetomidine, Fentanyl
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Helwan University
Pain Postoperative
Pregabalin and Analgesia After Laparoscopic Cholecystectomy
The purpose of this study is to evaluate how effective is the preoperative administration of pregabalin 600mg, to attenuate postoperative pain and opioids consumption after laparoscopic cholecystectomy.
- Trial name
- NCT01321801
- Testing
- Pregabalin
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Larissa University Hospital
Stomach Neoplasms, Pain
A Phase IV Randomized Trial of Maxigesic® Versus Standard Analgesia After Radical Gastrectomy
Background: Radical gastrectomy causes moderate-to-severe pain during the first 48 hours after surgery. Opioids are effective but carry adverse effects and risks of prolonged use, so ERAS-based care recommends multimodal…
- Conditions
- Stomach Neoplasms, Pain, Postoperative
- Trial name
- NCT07687394
- Testing
- Acetaminophen (Newaminophen Premix), Maxigesic IV (acetaminophen/ibuprofen)
- Volunteers
- 160 people
- Sponsor
- Yonsei University
Total Knee Arthroplasty
Compression Bandage in Local Infiltration Analgesia Afte Total Knee Arthroplasty
purpose: to determine wether a compression bandage prolongs analgesia of local infiltration analgesia after total knee arthroplasty
- Trial name
- NCT00485212
- Testing
- compression bandage
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Thumb Osteoarthritis
Magnesium as an Adjunct for Pain Treatment After Surgery for Thumb Base Arthrosis
A randomised controlled trial of addition to the standard pain treatment of 1000 mg oral magnesium citrate or placebo for 7 Days during surgery for thumb base arthrosis.
- Trial name
- NCT04613154
- Testing
- magnesiumcitrate
- Where
- Sweden
- Volunteers
- 9 people
- Sponsor
- Region Örebro County
Pain, Postoperative, Nerve Block
Paravertebral Blocks for Breast Cancer Surgery
This research project intends to look at the effect that a certain type of freezing injection, called a paravertebral block, has on the pain after an operation for breast cancer, the amount of pain relief that is needed and the…
- Trial name
- NCT01904266
- Testing
- GA + paravertebral block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Wound Healing and Prevention, Oral Inflammation
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation.
- Conditions
- Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management
- Trial name
- NCT07095556
- Testing
- Low-level laser therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Laparoscopic Nissen Fundoplication
Intraoperative Use of Dexketoprofen Trometamol, Pethidine Hcl, Tramadol Hcl and Their Combinations for Postoperative Pain Management in Laparoscopic Nissen Fundoplication
The purpose of this study is to evaluate the analgesic effects of dexketoprofen trometamol, tramadol hydrochloride, pethidine hydrochloride and their combinations in laparoscopic Nissen fundoplication.
- Trial name
- NCT01558622
- Testing
- dexketoprofen trometamol, tramadol hydrochloride, pethidine hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Kavaklıdere Umut Hospital
Postoperative Pain Management
Ultrasound-guided Erector Spinae Plane Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia of Adult Patients Undergoing Ovarian Cancer Surgery
Postoperative pain is one of the greatest patient concerns following any surgery. Although an increased emphasis has been placed on pain management, approximately 80% of surgical patients report postoperative pain with 86% of…
- Trial name
- NCT04434339
- Testing
- erector spinae block, transversus abdominis block
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Abdominal Hysterectomy
A Comparison Between Continuous and Intermittent Intraabdominal Analgesia Using Local Anaesthetics
The investigators hypothesis is that patient controlled local anesthetics administered intraabdominally are more efficacious compared to continuous infusion in reducing postoperative pain and morphine consumption.
- Trial name
- PoPuLAR (NCT01492075)
- Testing
- PCRA (Intermittent injection)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Örebro University, Sweden
Pneumonia, Cardiac Surgery
Catheter Outcomes With Sternotomy Cardiac Operated
Pneumonia occurs frequently in patients undergoing cardiac surgery and allows to increase their mortality. While chest physical therapy plays a crucial role to prevent postoperative pneumoniae, painful mobilization of the sternum…
- Conditions
- Pneumonia, Cardiac Surgery, Multiperforated Catheter, Analgesia
- Trial name
- STERNOCAT (NCT01648777)
- Testing
- L bupivacaine
- Where
- France
- Volunteers
- 1,502 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Maxillofacial Abnormalities, Maxillofacial Injuries
Vitamin C Level Effect in Orthognathic Surgery
Comparing the pre and post-operative blood plasma levels of vitamin C according to oxidative stress and investigate the correlation between post-operative analgesia requirement and vitamin C levels following orthognathic surgery.
- Conditions
- Maxillofacial Abnormalities, Maxillofacial Injuries, Maxillofacial Trauma
- Trial name
- NCT04416386
- Testing
- Vitamin C
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Pain, Postoperative
Providing Standardized Consented PROMs (Patient Reported Outcome Measures) for Improving Pain Treatment
PROMPT aims at improving management of acute and chronic pain by identifying a core set of PROMs (patient reported outcome measures) that are predictive indicators of treatment success in clinical practice and controlled trials.
- Trial name
- PROMPT (NCT03834922)
- Testing
- Prospective data collection
- Where
- Germany
- Volunteers
- 3,322 people
- Sponsor
- Prof. Dr. Winfried Meissner
Bladder Tumors, Spinal Anesthesia
Magnesium vs. Dexmedetomidine in TURBT Under Spinal Anesthesia
This randomized controlled trial evaluated the effects of intraoperative intravenous magnesium sulfate versus dexmedetomidine on postoperative pain, analgesic consumption, hemodynamic stability, and respiratory function in…
- Conditions
- Bladder Tumors, Spinal Anesthesia, Postoperative Pain, Magnesium Sulfate
- Trial name
- TURBT (NCT07445451)
- Testing
- magnesium sulfate, Dexmedetomidine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Inguinal Hernia Unilateral, Postoperative Pain Management
Transversalis Fascia Plane Block Versus Surgical Wound Infiltration for Postoperative Analgesia in Open Inguinal Hernia Repair
The purpose of this clinical trial is to evaluate whether two different analgesic techniques - ultrasound-guided Transversalis Fascia Plane Block (TFPB) and surgical wound infiltration - can improve postoperative pain control in…
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain Management, Regional Anaesthesia, Transversalis Fascia Plane Block
- Trial name
- TFPB-WIN (NCT07238829)
- Testing
- Ultrasound-Guided Transversalis Fascia Plane Block (TFPB), Surgical Wound Infiltration
- Volunteers
- 104 people
- Sponsor
- Ondokuz Mayıs University
Femoral Neck Fracture
Postoperative Pain Control After Hip Hemiarthroplasty: Intrathecal Morphine vs Periarticular Infiltration of Bupivacaine
Falls are a common problem in elderly people which they have to receive the operation. Hemiarthroplasty is one of the common orthopedics operations.
- Trial name
- NCT01219062
- Testing
- morphine, control, Bupivacaine
- Where
- 2 sites in Thailand
- Volunteers
- 10 people
- Sponsor
- Mahidol University
Breast Reduction, Postoperative Pain
Parasternal Block Added to Serratus Anterior Plane Block in Breast Reduction Surgery
This study aims to evaluate the effect of adding a Superficial Parasternal Intercostal Plane Block (PIPB) to the Serratus Anterior Plane Block (SAPB) on postoperative pain control in patients undergoing breast reduction surgery…
- Conditions
- Breast Reduction, Postoperative Pain, Opioid Consumption
- Trial name
- NCT07432256
- Testing
- Serratus Anterior Plane Block (SAPB), Serratus Anterior Plane Block (SAPB) and parasternal intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Zonguldak Bulent Ecevit University
Pain, Postoperative
Comparison of The Continous Suprainguinal Fascia Iliaca Compartment Block and Continous Epidural
This study evaluates the effectiveness of postoperative analgesia quality, Interleukin-6, Hemodynamic stability and QoR-40 of continuous Suprainguinal Fascia Iliaca Compartment Block (S-FICB) compared with continuous epidural in…
- Trial name
- NCT06636331
- Testing
- Continuous Suprainguinal Fascia Iliaca Compartment Block, Continuous Epidural
- Where
- 2 sites in Indonesia
- Volunteers
- 46 people
- Sponsor
- Udayana University
Surgery of Abdominoplasty With Flank Liposuction
Analgesic Effect Between TAP Block and Continuous Wound Infusion in Abdominoplasty Surgery
The purpose of this randomized controlled study is to compare the postoperative analgesic effect of a continuous wound infusion of local anesthetics and a sole transverse abdominal plan (TAP) regional block in the surgery of…
- Trial name
- NCT01862354
- Testing
- Transverse abdominal plan block, Continuous wound infusion
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University of Liege
Postoperative Pain, Postoperative Nausea and Vomiting
Ultrasound-guided Blocks for Ambulatory Knee Arthroscopy
In this study, we wish to investigate the effect of ultrasound (US) -guided block of the saphenous nerve (SN) and the posterior branch of the obturator nerve (ONP) on postoperative pain and the use of opioids (morphine-like pain…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Postoperative Function Level
- Trial name
- NCT01837394
- Testing
- Block of the SN and ONP, Paracetamol, Morphine
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Jens Borglum Neimann