Clinical trials: Postoperative Pain Relief
Pectus Excavatum, Chest Deformities
SPSIPB Versus SAPB for Postoperative Analgesia After Minimally Invasive Repair of Pectus Excavatum
This prospective observational cohort study will compare postoperative analgesic outcomes in patients undergoing minimally invasive repair of pectus excavatum.
- Trial name
- NCT07697222
- Testing
- Postoperative Analgesia Protocol, Bispectral Index Monitoring, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Marmara University
Sacral Erector Spinae Plane Block, Caudal Block
Sacral Erector Spinae Plane Block Versus Caudal Block in Penile Surgeries in Pediatrics
The study will be conducted to compare the efficacy of ultrasound guided Sacral Erector Spinae Plane Block to caudal block on pain management in penile surgeries in pediatrics.
- Conditions
- Sacral Erector Spinae Plane Block, Caudal Block, Penile Surgeries, Pediatrics
- Trial name
- NCT06235944
- Testing
- Caudal block, Sacral erector spinae block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Supratentorial Neoplasms
Comparison of Efficacy and Safety of the Postoperative Analgesia Methods
An optimal analgesic therapy is very important for postoperative recovery. In recent years, several studies showed that the prevalence of the moderate to severe pain after craniotomy ranged from 69 to 87% of patients.
- Trial name
- NCT02929147
- Testing
- Morphine, Dexketoprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Total Knee Arthroplasty
Saphenous Nerve Block Versus Femoral Nerve Block for Total Knee Arthroplasty
Currently, the regional anesthetic standard of care for total knee replacement surgery is combined spinal/epidural, with or without a femoral nerve block, or FNB.
- Trial name
- NCT01333943
- Testing
- Study Group: Experimental, Control Group
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Hospital for Special Surgery, New York
Total Hip Arthroplasty (THA), Postoperative Pain Management
Iliopsoas (IPB) and Pericapsular Nerve Group (PENG) Blocks Comparison on Analgesia and Recovery After Total Hip Arthroplasty
Background: In recent years, regional anesthesia has become more popular because it can reduce pain and the need for strong pain medications like morphine. For hip surgery, the PENG block is already known to be effective.
- Conditions
- Total Hip Arthroplasty (THA), Postoperative Pain Management, Peripheral Nerve Blocks, PENG Block
- Trial name
- NCT06964282
- Testing
- PENG Block, Iliopsoas nerve block
- Where
- Belgium
- Volunteers
- 118 people
- Sponsor
- University of Liege
Lumbar Disc Herniation, Postoperative Pain
Comparison of TLIP Block and QIP Block for Postoperative Analgesia After Lumbar Spine Surgery
This study compares two regional anesthesia techniques used for pain control after lumbar spine surgery: the classic thoracolumbar interfascial plane (TLIP) block and the quadratus lumborum-iliac plane (QIP) block.
- Trial name
- TLIP-QIP (NCT07750418)
- Testing
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Quadratus Lumborum-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Vezirköprü State Hospital
Knee Arthroplasty, Total, Peripheral Nerve Block
Postoperative Analgesia in Bilateral Knee Arthroplasties
To observationally compare the analgesic efficacy of LIA and S-FICB techniques and to record the pain scores of patients who underwent bilateral knee operations in the postoperative period.
- Conditions
- Knee Arthroplasty, Total, Peripheral Nerve Block, Pain, Postoperative
- Trial name
- NCT06357013
- Testing
- Bilateral Suprainguinal fascia iliaca compartment block, Local infiltration analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Post Operative Pain, Acute
A Comparative Study Between Ultrasound Guided Thoracic Paravertebral Block VS Serrartus Anterior Muscle Block in VATS as Regard Their Effectiveness in Post-operative Analgesia
A comparative study between ultrasound guided thoracic paravertebral block VS ultrasound guided serrartus anterior muscle block in video-assisted thoracoscopic surgeries as regard their effectiveness in post-operative analgesia
- Trial name
- NCT05971368
- Testing
- thoracic paravertebal block, serratus anterior muscle block
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cardiopulmonar Artery Bypass Grafting
Morphine Postoperative Analgesia and Pharmacokinetic/Pharmacodynamic Modeling
The currently available data are insufficient to develop a model that achieves optimum morphine dose individualization at the postoperative period of coronary artery bypass grafting (CABG).
- Trial name
- NCT01564420
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Sao Paulo
Breast Cancer Surgery Pain
The Effect of Nerve Blocks on Analgesia in Breast Cancer Surgery
Postoperative pain following modified radical mastectomy remains a significant clinical concern and may adversely affect patient recovery, opioid consumption, and overall patient satisfaction.
- Trial name
- breast surgery (NCT07601490)
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Serratus anterior plane block (SAP)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Postoperative Analgesia
Quadratus Lumborum in Cesarean Section Trial
Postoperative pain of a caesarean section may be of high intensity, especially in the first 48 hours after the procedure, which affects the mother / newborn relationship, in addition to having the potential to progress to chronic…
- Trial name
- QUALICS (NCT03673280)
- Testing
- Quadratus Lumborum Block
- Where
- Brazil
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Hip Arthroplasty, Postoperative Pain
DIPB vs. SIFIB for Postoperative Analgesia After Hip Surgery
This randomized, double-blind clinical trial aims to compare the effectiveness of the Deep Iliacus Plane Block (DIPB) and the Suprainguinal Fascia Iliaca Block (SIFIB) for postoperative pain control in patients undergoing primary…
- Conditions
- Hip Arthroplasty, Postoperative Pain, Regional Anesthesia, Acute Postoperative Pain
- Trial name
- NCT07452120
- Testing
- Suprainguinal Fascia Iliaca Block, Deep Iliacus Plane Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sivas Numune Hospital
Nephrolithiasis, Postoperative Pain
Effect of a Low-Dose Ketamine-Dexmedetomidine-Based Opioid-Sparing Anesthesia Protocol on Postoperative Quality of Recovery After Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is a minimally invasive surgical procedure used to remove large or complex kidney stones. Although effective, dilation of the surgical tract and the placement of a nephrostomy tube cause…
- Conditions
- Nephrolithiasis, Postoperative Pain, Quality of Recovery
- Trial name
- NCT07855068
- Testing
- Ketamine and Dexmedetomidine, Fentanyl
- Volunteers
- 100 people
- Sponsor
- Assiut University
Postoperative Analgesia
Erector Spinae Block Using a Dexmedetomidine Versus Magnesium Sulfate as an Adjuvant to Bupivacaine
This prospective parallel group randomized study will be conducted over 52 adult participants between 20 and 60 years ASA (American Association of Anesthesiologists) I and II undergoing lumbar spine surgery.
- Trial name
- NCT05694897
- Testing
- Erector spinae block using bupivacaine 0.25% and magnesium sulfate, Erector spinae block using bupivacaine and dememdetomidine
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Postoperative Pain
Dexmedetomidine Wound Infiltration in Cesarean Section
The effects of four different wound infiltration protocols in cesarean section will be investigated on parturient' pain intensity, PCA morphine consumption given, side effects and parturient' overall satisfaction.
- Trial name
- NCT03382938
- Testing
- Dexmedetomidine, Ropivacaine, Dexmedetomidine - Ropivacaine
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
Pain Relief in Post Operative Patient
Comparison of Pain ReliefofBupivacaineWith Dexmedetomidine and Bupivacaine Alone in TransversusAbdominisPlane Block For Postoperative Anelgesia in Patients Undergoing Abdominal Surgeries
Postoperative pain related to abdominal surgeries poses significant burden on the healthcare system, in terms of increased use of different analgesics, delayed ambulation, pulmonary complications, DVT, and prolonged hospital…
- Trial name
- NCT05244252
- Testing
- dexmeditomidine and bupivacaine, Bupivacaine
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Medical College
Diabetes Mellitus, Nerve Block Duration
Infraclavicular Block Properties in Diabetic Patients
Background and objectives: The investigators are performing this study to explore whether the presence of diabetes mellitus (DM) will affect the outcomes of infraclavicular brachial plexus blocks (ICBs) in patients undergoing…
- Conditions
- Diabetes Mellitus, Nerve Block Duration, Pain, Postoperative
- Trial name
- NCT03486535
- Testing
- Infraclavicular Brachial Plexus Blocks
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Post-operative Analgesia, CSOM - Chronic Suppurative Otitis Media
Preemptive Pregabalin in Myringoplasty
The aim of this study was to investigate the effect of preemptive pregabalin on post-operative pain reduction after myringoplasty.
- Trial name
- NCT03603626
- Testing
- Pregabalin 150mg
- Where
- Nepal
- Sponsor
- Dhulikhel Hospital
Postoperative Analgesia
Analgesic Effect of Adductor Canal Block With and Without Dexamethasone for Knee Arthroscopy
The purpose of this study was to evaluate the efficacy of ultra-sound guided adductor canal block with and without dexamethasone when added to bupivacaine on the duration of postoperative analgesia in patients undergoing…
- Trial name
- NCT03239314
- Testing
- Saline Solution, Dexamethasone
- Volunteers
- 60 people
- Sponsor
- Assiut University
Modified Radical Mastectomy, Postoperative Analgesia
Duloxetine for Postoperative Analgesia After Modified Radical Mastectomy
The aim of this study is to evaluate the role of duloxetine in controlling pain after radical mastectomy.
- Trial name
- NCT05442268
- Testing
- Acetaminophen group, Duloxetine group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University