Clinical trials: Postoperative Pulmonary Complication
Cancer, Heart Failure
Evaluation of Preoperative Acceptance of Proactive Palliative Care Intervention
Advances in medicine have led to an increased life expectancy even with complex disease courses of malignant diseases. This leads to frequent critical situations for patients and high risk surgical interventions.
- Conditions
- Cancer, Heart Failure, Chronic Obstructive Pulmonary Disease, Postoperative Complications
- Trial name
- iCare (NCT05575791)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
COVID-19, Surgery
The Effect of COVID-19 Infection on Post-operative Complications
We did an multi-centre, observational cohort study in patients who had surgery in 2023. We included participants who underwent surgery after the COVID-19 to lift the lockdown in China.
- Conditions
- COVID-19, Surgery, Postoperative Complications
- Trial name
- NCT05677815
- Testing
- Underwent Surgery from 2019 to 2022
- Where
- China
- Volunteers
- 3,350 people
- Sponsor
- Xijing Hospital
Post-Amputation Pain, Phantom Limb Pain
Electrical Nerve Block for Amputation Pain
The purpose of the clinical trial is to learn whether electrical nerve block via the Altius System is a safe and effective treatment for patients with post-amputation pain.
- Conditions
- Post-Amputation Pain, Phantom Limb Pain, Residual Limb Pain, Stump Pain
- Trial name
- NCT02221934
- Testing
- Altius
- Where
- 22 sites in United States
- Volunteers
- 607 people
- Sponsor
- Neuros Medical, Inc.
Postoperative Pulmonary Complications, Atelectasis
The Effect of the 5T Teach-Back Method on Respiratory Exercise and Incentive Spirometer Training
Breathing problems after surgery are common and can lead to serious complications such as low oxygen levels, lung collapse, or pulmonary embolism.
- Conditions
- Postoperative Pulmonary Complications, Atelectasis, Patient Education, Respiratory Exercises
- Trial name
- TEACH-BREATHE (NCT07350616)
- Testing
- 5T Teach-Back-Based Respiratory Exercise and Incentive Spirometer Education, Standard Verbal Respiratory Education
- Volunteers
- 76 people
- Sponsor
- Suleyman Demirel University
Mechanical Ventilation Complication, Pediatric ALL
Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
Postoperative pulmonary complications (PPCs) are common in children undergoing general anesthesia and are associated with prolonged stay in the hospital and high costs.
- Conditions
- Mechanical Ventilation Complication, Pediatric ALL, Pulmonary Complication, Perioperative/Postoperative Complications
- Trial name
- BIG APPLE (NCT06166706)
- Where
- 4 sites in Australia, Italy and 2 more
- Volunteers
- 10,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Post-Op Complication, Ventilator-Induced Lung Injury
Optimization of PEEP During Laparoscopic Surgery
Lung-protective ventilation (LPV) during general anesthesia can trigger the development of early postoperative pulmonary complication (PPC) and ventilator associated lung injury.
- Trial name
- NCT05222893
- Testing
- Respiratory monitoring, Capnography, Arterial blood gas
- Where
- Kazakhstan
- Volunteers
- 60 people
- Sponsor
- Karaganda Medical University
Postoperative Complications
Crystalloids vs Albumin Prime Solution and Postoperative Pulmonary Complications
In 2019, the investigators initiated a new priming fluid therapy strategy in the cardiopulmonary bypass (CPB) machine for patients undergoing pulmonary endarterectomy surgery.
- Trial name
- ALBUTEP (NCT04839432)
- Testing
- implementation of albumin solution in the priming of the cardiopulmonary bypass machine
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Erasme University Hospital
Postoperative Pain, Lung Cancer
Pain After Lung Cancer Surgery - Comparing Traditional Versus Prolonged Release Nerve Blockades
To investigate the effect of liposomal bupivacaine compared with bupivacaine hydrochloride for intercostal blockades for patients undergoing Video-assisted thoracoscopic surgery.
- Conditions
- Postoperative Pain, Lung Cancer, Video Assisted Thoracoscopic Surgery, Blockades Neuromuscular
- Trial name
- NCT05038007
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Jannie Bisgaard Stæhr
Locally Advanced Non-small Cell Lung Cancer (NSCLC)
Effect of Pre-operative Exercise Training on Cardiorespiratory Fitness in Patients With Locally Advanced Non-small Cell Lung Cancer Undergoing Induction Chemo-immunotherapy Followed by Surgery - a Randomized Controlled Study
The PREHAB study focuses on patients with locally advanced non-small cell lung cancer (NSCLC) undergoing neoadjuvant chemotherapy and/or immunotherapy prior to surgical resection.
- Trial name
- PREHAB (NCT07479407)
- Testing
- Preoperative Exercise Training
- Where
- 3 sites in Switzerland
- Volunteers
- 74 people
- Sponsor
- Hôpital du Valais
Neuromuscular Blockade
The Effect of Deep Neuromuscular Blockade on Respiratory Mechanics
This study is a randomized, controlled, double-blinded, and parallel design study. A total 58 patients were randomized to receive a deep block or a moderate block scheduled for elective robot assisted laparoscopic radical…
- Trial name
- NCT04174222
- Testing
- Moderate NMB, Deep NMB
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Lung Cancer, Perioperative/Postoperative Complications
Lung Rehabilitation in Treating Patients With Chronic Obstructive Pulmonary Disease Who Are Undergoing Surgery for Lung Cancer
RATIONALE: Exercise may help improve lung function and lessen complications of surgery in patients with chronic obstructive pulmonary disease who are undergoing surgery for lung cancer.
- Conditions
- Lung Cancer, Perioperative/Postoperative Complications, Pulmonary Complications, Tobacco Use Disorder
- Trial name
- NCT00363428
- Testing
- exercise intervention, smoking cessation intervention, counseling intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Mayo Clinic
Complication of Ventilation Therapy, Postoperative Respiratory Complications
Intraoperative Protective Ventilation and Postoperative Pulmonary Complications
The purpose of this pilot study is to identify the optimal way to ventilate patients during abdominal surgery in order to reduce the amount of post-operative pulmonary complications in patients at moderate and high-risk for them.
- Trial name
- NCT02671721
- Testing
- Maximal Compliance, Transpulmonary Pressure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Postoperative Pulmonary Complications (PPCs)
Prediction of Postoperative Pulmonary Complications in Thoracic Surgery
Lung cancer is a common disease, and its treatment is lobectomy or pulmonary segmentectomy. In France, approximately 8,000 patients undergo this procedure each year, but it remains associated with significant Postoperative…
- Trial name
- PREDICT-PPC (NCT07359885)
- Testing
- Evaluation of prognostic performance of a defined score using a machine learning method (STABL: Stability Selection) integrating immune data (cytometric and proteomic)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Rouen
Postoperative Pulmonary Complications (PPCs), Preoperative Functional Status
Physical Function Before Surgery and Lung Complications After Lung Surgery
This study will examine whether patients' ability to perform everyday physical activities before lung surgery is related to their risk of developing lung complications after surgery.
- Trial name
- NCT07853430
- Testing
- Preoperative Functional Status Assessment
- Volunteers
- 450 people
- Sponsor
- Aerospace Center Hospital
Neurosurgery, Phrenic Nerve Stimulation
Intraoperative Diaphragmatic Neuromodulation
This prospective, single-center, randomized controlled clinical trial aims to investigate the impact of intraoperative phrenic nerve stimulation (i.e., diaphragmatic neuromodulation) on postoperative complications in…
- Conditions
- Neurosurgery, Phrenic Nerve Stimulation, Postoperative Delirium
- Trial name
- NCT06518707
- Testing
- Phrenic nerve stimulation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Sanbo Brain Hospital
Carcinoma, Non-Small-Cell Lung
Comprehensive Geriatric Assessment and Complications Following Lung Resection for Lung Cancer
schema : Prospective prognostic study The main objective is to study the value of the Comprehensive Geriatric Assessment in predicting the risk of post operative complications after lung resection for cancer.
- Trial name
- OPERAGE (NCT01956331)
- Where
- 25 sites in France
- Volunteers
- 302 people
- Sponsor
- Groupe Francais De Pneumo-Cancerologie
Cardiac Surgery
Interest of the Not Invasive Ventilation Used in Meadow and Post-operative of Cardiac Surgery
After cardiac surgery, many complications can arise, in particular at the cardiac and lung level and it is true especially as the patient is with comorbidity.
- Trial name
- CAPVNI (NCT02302300)
- Testing
- Manufacturer STELLAR 150
- Where
- France
- Volunteers
- 216 people
- Sponsor
- University Hospital, Brest
Electrical Impedance Tomography (EIT), Postoperative Pulmonary Complications (PPCs)
EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery
This study is a prospective, single-center, single-blind, randomized controlled clinical trial. Patients scheduled for laparoscopic bariatric surgery will be selected and randomly assigned to either the EIT-guided individualized…
- Conditions
- Electrical Impedance Tomography (EIT), Postoperative Pulmonary Complications (PPCs), Recruitment, Mechanical Ventilation Complication
- Trial name
- EIT (NCT07207772)
- Testing
- Group P-eit, Group P-8
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Jianbo Wu
Hypoxemia, Postoperative Complications
Sigh Ventilation on Postoperative Hypoxemia in Cardiac Surgery
Postoperative pulmonary complications (PPCs) remain a frequent event after pump-on cardiac surgery and are mostly characterized by postoperative hypoxemia.These complications are significant contributors to prolonged intensive…
- Conditions
- Hypoxemia, Postoperative Complications, Cardiac Disease, Acute Lung Injury
- Trial name
- NCT06248320
- Testing
- Sigh ventilation
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Zhongda Hospital
Obstructive Sleep Apnea, Postoperative Complications
Postoperative Pulmonary Complications In Obstructive Sleep Apnea Patients
It is known that perioperative respiratory complications occur more often in obstructive sleep apnea syndrome (OSAS) patients during general anesthesia.
- Trial name
- NCT06041750
- Testing
- Elective surgical procedure under general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Cukurova University