Clinical trials: Postoperative Pulmonary Complication
Coronary Arterial Disease (CAD), Coronary Artery Bypass Graft (CABG)
Comparison of Oxygen Reserve Index and Spirometry in Predicting Respiratory Complications After Coronary Artery Bypass Surgery
Coronary artery disease (CAD) is one of the most common cardiac conditions, primarily caused by atherosclerosis. Studies have shown that environmental factors such as lifestyle, diet, genetics, and air pollution contribute to the…
- Conditions
- Coronary Arterial Disease (CAD), Coronary Artery Bypass Graft (CABG), Postoperative Pulmonary Complication
- Trial name
- NCT07063277
- Testing
- Preoperative Evaluation with ORI and Spirometry
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Ankara Bilkent Sehir Hastanesi
Postoperative Complications, Physical Activity
Preoperative Exercise for Patients Undergoing Complex Cancer Surgery
Treatment for people with cancer of the lung or the oesophagus (food-pipe) often involves surgery. This surgery is complex and there is a high risk that patients will develop severe complications afterwards, leading to a longer…
- Conditions
- Postoperative Complications, Physical Activity, Surgery--Complications
- Trial name
- PRE-HIIT (NCT03978325)
- Testing
- Control, Exercise - HIIT Intervention
- Where
- Ireland
- Volunteers
- 78 people
- Sponsor
- University of Dublin, Trinity College
IHD, Valve Heart Disease
Role of Chest Ultrasound in Detection of Post-operative Pulmonary Complications After Cardiothoracic Surgery
assess feasibility of detecting pulmonary complications postoperative using chest ultrasound compared to chest x-ray measure time lag between using ultrasound and using chest x-ray to detect pulmonary complications postoperative
- Conditions
- IHD, Valve Heart Disease, Surgery--Complications
- Trial name
- NCT04118621
- Testing
- chest ultrasound
- Volunteers
- 100 people
- Sponsor
- Assiut University
Lung Neoplasm, Adult ALL
LUS to Assess Lung Injury After Lung Lobectomy
The purpose of the study is to assess whether lung ultrasound is able to detect lung injury after lung resection surgery.
- Conditions
- Lung Neoplasm, Adult ALL, Lung Injury, Lung Inflammation
- Trial name
- OPEN THORUS (NCT04755478)
- Testing
- Thoracotomy, VATS
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital General Universitario de Valencia
Postoperative Pain
Pain Control of Thoracoscopic Major Pulmonary Resection
The purpose of this study is to evaluate whether pre-emptive local bupivacaine injection is a better alternative pain control modality than the conventional intravenous patient controlled analgesia.
- Trial name
- NCT01758809
- Testing
- Pre-emptive bupivacaine wound infiltration, intravenous patient controlled analgesia
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Bundang Hospital
Arrhythmia, Acute Kidney Injuries
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil.
- Conditions
- Arrhythmia, Acute Kidney Injuries, Sepsis, Pneumopathy
- Trial name
- PEDS-CARE (NCT06985082)
- Testing
- THERE IS NOT A INTERVENTION
- Volunteers
- 310 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Postoperative Pain, Thoracic Surgery Lung
Analgesic Efficacy and Hemodynamic Stability of Ultrasound-guided Thoracic Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Pediatric Thoracic Surgery: a Randomized Controlled Trial.
Thoracic surgery in children is considered a highly invasive procedure that significantly affects respiratory mechanics and cardiovascular function, resulting in substantial physiological disturbances during the perioperative…
- Conditions
- Postoperative Pain, Thoracic Surgery Lung, Thoracotomy Analgesia, Regional Anesthesia
- Trial name
- NCT07602179
- Testing
- Thoracic erector spinae plane block (ESPB), Thoracic epidural analgesia (TEA)
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- Nguyen Dang Thu
Postoperative Pulmonary Complications, Postoperative Pulmonary Atelectasis
Evaluation of the Effect of Perioperative Recruitment Maneuver Practice on Lung Ultrasound Score and Mechanical Power in Pediatric Patients
Pulmonary atelectasis is common during general anesthesia and increases the risk of hypoxemia, especially in pediatric patients. PEEP and recruitment maneuvers (RM) are effective in preventing atelectasis.
- Conditions
- Postoperative Pulmonary Complications, Postoperative Pulmonary Atelectasis, Pediatric Surgery
- Trial name
- LUS RM PEEP (NCT07294560)
- Testing
- recruitment maneuver, right and left lateral decubitus position recruitment maneuvers
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Pain, Acute, Lung Cancer
Thoracic Surgery Intercostal Block Trial With Liposomal vs. Hydrochloride Bupivacaine
This randomized controlled trial evaluates the analgesic effects of liposomal bupivacaine compared to bupivacaine hydrochloride in intercostal nerve block for patients undergoing thoracoscopic lung surgery.
- Trial name
- NCT07134660
- Testing
- Liposomal Bupivacaine intercostal nerve block, Bupivacaine Hydrochloride intercostal nerve block, Standard Postoperative Analgesia
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Hernia, Ventral, Hernia Incisional
Renal- and Pulmonary Function in Relation to Abdominal Hypertension After Abdominal Reconstruction
An incisional hernia is technically challenging to operate and is the most frequent long-term complication after open surgery, resulting in impaired quality of life and reduced physical ability.
- Conditions
- Hernia, Ventral, Hernia Incisional, Acute Kidney Injury, Restrictive Lung Disease
- Trial name
- REPARE (NCT04143776)
- Testing
- Abdominal reconstruction
- Where
- Denmark
- Sponsor
- Bispebjerg Hospital
Colorectal Surgery, Postoperative Pulmonary Complications (PPCs)
Dorsal Vetilation and PPCs in Colorectal Cancer Surgery Patients
Postoperative pulmonary complications (PPCs) are common in patients after major abdominal surgery. It has been shown that 5-40% of patients occur PPCs after major surgery, and the mid to high PPC rate is observed after…
- Trial name
- NCT06662799
- Where
- China
- Volunteers
- 92 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Obesity, Postoperative Pulmonary Complications
Comparison of Standard Versus Dynamic Compliance-Guided Individualized PEEP in Obese Patients Undergoing Spinal Surgery
This study aims to compare standard positive end-expiratory pressure (PEEP) with dynamic compliance-guided individualized PEEP in obese patients undergoing elective spinal surgery under general anesthesia.
- Conditions
- Obesity, Postoperative Pulmonary Complications, Mechanical Ventilation
- Trial name
- NCT07388719
- Testing
- Standard PEEP
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Konya City Hospital
Postoperative Complications, Neuromuscular Blockade
The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications
Substantial respiratory morbidity has been associated with postoperative residual paralysis, which is fairly common after general anesthesia involving a neuromuscular blocking agent.
- Trial name
- NCT02861131
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Postoperative Pulmonary Complications
Assessment of Oxygen Delivery as an Early Predictor of Postoperative Pulmonary Complications During One-lung Pulmonary Ventilation in Thoracic Surgery. A Pilot Study
This is a simple descriptive pilot study where 60 patients undergoing One-lung ventilation (OLV) for > 120 minutes during esophagectomy will be enrolled to see if the Flo Trac® system can identify hypoxemia earlier than the…
- Trial name
- DO2 and POPCs (NCT05154617)
- Testing
- Standard surgical monitoring, along with the Flo Trac® system monitoring.
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Emergence Delirium, Postoperative Delirium
Verification of a New Predictive Delirium Score in Adults With Elective Cardiac Valve or Bypass Surgery With Perioperative Use of a Heart-lung Machine; a Monocentric Pilot Observational Study
Basics (state of scientific knowledge): Delirium is an acute disturbance of consciousness and attention that develops over a short period of time and fluctuates in severity.
- Trial name
- MO-FA2-(TB) (NCT07276503)
- Volunteers
- 100 people
- Sponsor
- University Hospital Tuebingen
Ventilator-Induced Lung Injury
Intraop Ventilation Management and Postop Pulmonary Complications in High Risk Patients for OSA
Lung protective ventilation (LPV) has been proposed to reduce the incidence of postoperative pulmonary complications (PPCs), and protect against ventilator induced lung injury (VILI).
- Trial name
- NCT03135691
- Where
- United States
- Sponsor
- Ohio State University
Respiration, Artificial, Lung Diseases
Impact of Lung Recruitment Maneuvers on Driving Pressure in Cardiac Surgery
In anesthesia the incidence of postoperative pulmonary complications is frequent, especially in cardiac surgery where the incidence can reach 10%.
- Conditions
- Respiration, Artificial, Lung Diseases, Atelectasis, Cardiac Surgical Procedures
- Trial name
- IMPREMO (NCT03976947)
- Where
- France
- Volunteers
- 217 people
- Sponsor
- University Hospital, Caen
Cardiac Surgery, Elderly Patient
Preoperative Nutritional Status Scores to Predict PPC in Elderly With Cardiac Surgery
This prospective study investigates prognostic values and compares the role of nutritional status by using GNRI, MNA-SF, PNI, and NAF in predicting post-operative pulmonary complication among elderly patients with cardiac surgery.
- Conditions
- Cardiac Surgery, Elderly Patient, Postoperative Pulmonary Complication, Nutrition Scoring System
- Trial name
- NCT06340464
- Testing
- Nutrition scoring systems
- Where
- Thailand
- Volunteers
- 217 people
- Sponsor
- Prince of Songkla University
Pulmonary Complications, Inflammatory Response
Intraoperative PEEP Optimization: Effects on Postoperative Pulmonary Complications and Inflammatory Response
The purpose of this prospective randomized controlled trial is to determine the effects of intraoperative lung protective mechanical ventilation using an individual optimal PEEP value on postoperative pulmonary complications and…
- Trial name
- NCT02931409
- Testing
- Optimal PEEP, Standard PEEP
- Where
- 2 sites in Hungary
- Volunteers
- 40 people
- Sponsor
- Péterfy Sándor Hospital
Heart Attack, Cardiac Arrest
Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Based on limited published epidemiological data, up to an alarming 1 in 50 surgical inpatients die within 30 postoperative days.
- Conditions
- Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- SATISFY-SOS (NCT02032030)
- Where
- United States
- Volunteers
- 73,952 people
- Sponsor
- Washington University School of Medicine