Clinical trials: Postoperative Sleep
Pain, Postoperative, Tonsillar Hypertrophy
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea
- Trial name
- OPTIMAL (NCT06576830)
- Testing
- Methadone, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Duke University
Gynecologic Neoplasms
Impact of Preoperative Sleep Quality and Anxiety on Postoperative Outcomes in Abdominal Gynecologic Cancer Surgery
This prospective observational study aims to evaluate the effects of preoperative sleep quality and anxiety levels on postoperative outcomes in patients undergoing abdominal gynecologic cancer surgery.
- Trial name
- NCT07036549
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Izmir City Hospital
Chronic Post-Surgical Pain
Effect of Perioperative Dexmedetomidine on Chronic Post-Surgical Pain
The goal of this clinical trial is to learn if intranasal dexmedetomidine works to improve sleep quality to treat chronic post-surgical pain (CPSP) in patients undergoing thoracic surgery.
- Trial name
- NCT06849466
- Testing
- Dexmedetomidine, Saline solution
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Peking Union Medical College Hospital
Esketamine, Sleep Disturbance
Esketamine on Postoperative Sleep Disturbance of Patients Undergoing Spinal Surgery
The goal of this clinical trial is to learn about the effect of intraoperative esketamine infusion on postoperative sleep disturbance(PSD) of patients undergoing spinal surgery.
- Conditions
- Esketamine, Sleep Disturbance, Spinal Surgery
- Trial name
- NCT06451627
- Testing
- Esketamine, saline
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital
Sleep Quality of Patients Undergoing TURP
Postoperative Sleep Quality of Patients Sedation With i.v. Dexmedetomidine or Midazolam Undergoing TURP
The investigators designed a study to determine whether dexmedetomidine versus midazolam combined with spinal anesthesia would provide same postoperative sleep quality in patients undergoing transurethral prostatic resection.
- Trial name
- NCT02142595
- Testing
- dexmedetomidine, Midazolam
- Where
- China
- Volunteers
- 111 people
- Sponsor
- China Medical University, China
Delirium - Postoperative, Sleep Problems
Preoperative Sleep Intervention on Postoperative Delirium in School-aged Children Undergoing Congenital Heart Surgery
This is a multicenter, randomized, controlled clinical trial aimed to determine whether preoperative sleep interventions could reduce the incidence of adverse outcomes, such as postoperative delirium, in sleep-disordered…
- Conditions
- Delirium - Postoperative, Sleep Problems, Congenital Heart Disease (CHD)
- Trial name
- NCT06879431
- Testing
- cognitive-behavioral intervention
- Where
- China
- Volunteers
- 544 people
- Sponsor
- Yan Fuxia
Cystic Adenomatoid Malformation of Lung, Congenital, Bronchopulmonary Sequestration
Effect of Ultrasound-guided Erector Spinae Plane Block on Postoperative Pain and Sleep Quality of Infants With Congenital Pulmonary Cystic Disease After Thoracoscopic Surgery
This study intends to evaluate the effect of erector spinae plane block on postoperative analgesia and sleep quality in infants with congenital cystic pulmonary disease after thoracoscopic surgery, and provides reference for…
- Conditions
- Cystic Adenomatoid Malformation of Lung, Congenital, Bronchopulmonary Sequestration, Bronchogenic Cyst
- Trial name
- NCT06498583
- Testing
- Ropivacaine, erector spinae plane block, Incision infiltration of local anesthesia
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Lei Xiaoming
Transcranial Electrical Stimulation
Transcranial Electrostimulation and Obstructive Sleep Apnea Surgery
Postoperative pain after major surgery for obstructive sleep apnea (OSA), such as palatopharyngoplasty (PPP) and maxillomandibular advancement (MMA) is moderate-to-severe, and may persist for weeks.
- Trial name
- NCT03735004
- Testing
- Transcranial electrostimulation (TES)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Chronic Tonsillitis, Sleep Disordered Breathing
Outcomes of Post-operative Diet in Children Following Tonsillectomy and Adenoidectomy
This research is being done because it is not known which dietary recommendations are best to help patients recover after a tonsillectomy and/or adenoidectomy.
- Trial name
- NCT03437954
- Testing
- Diet modification
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Georgetown University
Sleep Disordered Breathing
Evaluation of Sleep Disordered Breathing Following Ambulatory Surgery
Obstructive sleep apnea (OSA) is a relatively common medical condition that includes upper-airway obstruction and consequent cessation of breathing during sleep with significant associated other medical problems.
- Trial name
- NCT01851798
- Testing
- Home sleep test administered to all enrolled subjects
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Walter Reed National Military Medical Center
Total Knee Arthroplasty (TKA)
Effect of Preoperative Sleep Disturbance on Postoperative Pain and Recovery
The study subjects consisted of patients who underwent elective total knee arthroplasty (TKA) at Gansu Provincial Hospital of TCM from November 2023 to January 2024.
- Trial name
- NCT06815744
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Gansu Provincial Hospital
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Low Anterior Resection Syndrome, Rectal Cancer Surgery
Transanal Irrigation for Low Anterior Resection Syndrome
The preservation surgery of the anal sphincter muscle has become the standard procedure in the treatment of rectal cancer and, thanks to advancements in surgical techniques, can now be performed for tumors located closer to the…
- Conditions
- Low Anterior Resection Syndrome, Rectal Cancer Surgery, Insomnia
- Trial name
- TraLARS (NCT06796296)
- Testing
- Transanal Irrigation (TAI)
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Seoul National University Hospital
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Vagus Nerve Stimulation
Transauricular Vagus Nerve Stimulation Improves Postoperative Sleep Disorders in Elderly Patients.
Postoperative sleep disorder is one of the common complications after general anesthesia. Compared to patients of various ages, elderly patients have a much higher incidence of postoperative sleep disturbance.
- Trial name
- Vnstep (NCT06421051)
- Testing
- Transauricular Vagal Nerve Stimulation
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Beijing Tiantan Hospital
Preoperative Anxiety, Virtual Reality
The Effect of Virtual Reality Education on Preoperative Anxiety, Postoperative Pain, and Sleep in Patients Undergoing Colon Surgery
The effect of patient education given to patients undergoing colon surgery using virtual reality in the preoperative period on preoperative anxiety, postoperative pain and sleep is the subject of this study.
- Conditions
- Preoperative Anxiety, Virtual Reality, Postoperative Pain Management, Postoperative Sleep
- Trial name
- NCT07297095
- Testing
- preoperative patient education via virtual reality device
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Yildirim Beyazıt University
Postoperative Sleep Quality
Postoperative Sleep Quality of Patients Anesthesia With Propofol or Sevoflurane Undergoing Thyroidectomy
The investigators designed a study to determine whether Propofol or Sevoflurane would provide same postoperative sleep quality in patients undergoing thyroidectomy.
- Trial name
- NCT02146976
- Testing
- propofol, sevoflurane
- Where
- China
- Volunteers
- 124 people
- Sponsor
- China Medical University, China
Postoperative Delirium
Postoperative Delirium: EEG Markers of Sleep and Wakefulness
Postoperative delirium is a condition in which patients develop temporary difficulties in maintaining attention and thinking clearly. These new problems can appear after surgery and change throughout the day.
- Trial name
- NCT03291626
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Washington University School of Medicine
Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery
Effect of Subanesthetic Dose of Esketamine on Sleep Quality and Recovery of Gastrointestinal Function in Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery in the Early Postoperative Period
Patients undergoing gynecological surgery are at high risk of developing postoperative sleep disorders. Intraoperative opioid use is detrimental to the patient's postoperative recovery of gastrointestinal function.
- Trial name
- NCT05715671
- Testing
- esketamine
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Zhuan Zhang
Obstructive Sleep Apnea, Arrhythmia
Evaluation of Sleep Apnea and Cardiac Rhythm Abnormalities After Surgery Under General Anesthesia
Higher risk of cardiac and respiratory post-operative events is observed in patients with unrecognised Obstructive Sleep Apnea (OSA).
- Trial name
- Etude3A (NCT02833662)
- Testing
- Measure of ODI and heart rhythm
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble