Clinical trials: Postpartum Depression (PPD), open to volunteers
Doula Support, Postpartum
The Goal is to Examine the Impact of Doula-delivered, Nurse-coordinated Postpartum Care Among Individuals With Preterm Births <34 Weeks' Gestation Requiring NICU Admission.
The primary objective of this research is to conduct a randomized clinical trial to examine the impact of nurse-coordinated, doula-delivered postpartum support (intervention arm) on postpartum health care utilization, health…
- Conditions
- Doula Support, Postpartum, Postpartum Depression (PPD), Postpartum Anemia
- Trial name
- NEST (NCT07787845)
- Testing
- Doula-delivered, Nurse-coordinated postpartum support
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of South Carolina
Postpartum Depression (PPD), Postpartum Anxiety
AI-Enabled Wearable Monitoring for Detection of Postpartum Depression and Anxiety
The goal of this observational study is to examine whether passively collected wearable data can be used to predict onset and severity of postpartum depression and anxiety symptoms. The main questions it aims to answer are: 1.
- Trial name
- NCT07866053
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Postpartum Depression (PPD), Breastfeeding
Methyl Donor-Rich Diet in the Postpartum Period
This study aims to evaluate the effects of a methyl-donor-rich diet during the postpartum period on maternal depression, breastfeeding success, and infant weight.
- Conditions
- Postpartum Depression (PPD), Breastfeeding, Maternal Nutrition, Infant Development
- Trial name
- NCT07887178
- Testing
- Methyl Donor-Rich Dietary Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Postpartum, Postpartum Depression (PPD)
Postpartum Care in the NICU Multi-Site
Parents of infants admitted to the neonatal intensive care unit (NICU) face unique challenges in caring for their own health after giving birth.
- Conditions
- Postpartum, Postpartum Depression (PPD), Hypertension Disorders in Pregnancy, Postpartum Anxiety
- Trial name
- PeliCaN (NCT07873190)
- Testing
- Postpartum Doula Support in the NICU
- Where
- 14 sites in United States
- Volunteers
- 756 people
- Sponsor
- Children's Hospital of Philadelphia
Postpartum Depression (PPD), Alcohol Use
Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms.
- Conditions
- Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
- Trial name
- MOMS-AD (NCT07485036)
- Testing
- Contingency Management & Problem Solving Therapy, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois at Chicago
Postpartum Depression (PPD)
SAINT in Postpartum Depression (PPD)
This study is a large, multi-site clinical trial testing whether Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT), a fast-acting form of repetitive transcranial magnetic stimulation (rTMS), can more effectively…
- Trial name
- NCT07210255
- Testing
- SAINT Neuromodulation System
- Where
- 4 sites in United States
- Volunteers
- 192 people
- Sponsor
- Magnus Medical
Pregnancy, Post Partum
Deconstructing Maternal Burdens: Doulas and the Community Unite for Health
This study is a randomized controlled trial comparing two models of doula support for pregnant individuals enrolled in Medicaid: an enhanced doula support model, in which support starts earlier in pregnancy, occurs more…
- Conditions
- Pregnancy, Post Partum, Doula Care, Postpartum Depression (PPD)
- Trial name
- UNITE (NCT07799805)
- Testing
- Doula, Standard (non-enhanced) Medicaid doula support
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- University of Florida
Postpartum Depression (PPD)
Treatment of Anaemia After Caesarean With Intravenous Versus Oral Iron and Postpartum Depression
The objectif of the IRON-DEP Study is to assess the efficacy of intravenous (IV) versus oral iron treatment on the prevalence of postpartum depression (PPD) in women with moderate iron deficiency anemia after caesarean delivery.
- Trial name
- IRON-DEP (NCT06833788)
- Testing
- Ferric carboxymaltose IV, TIMOFÉROL®
- Where
- France
- Volunteers
- 2,860 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postpartum Anxiety, Postpartum Depression (PPD)
Narrative Nursing for Cesarean Mothers' Anxiety and Breastfeeding Confidence
This study tests whether a nurse-led "4-step narrative nursing" program can reduce anxiety and improve breastfeeding confidence in mothers who are having a planned or non-emergency cesarean section.
- Conditions
- Postpartum Anxiety, Postpartum Depression (PPD), Breastfeeding Self-Efficacy, Cesarean Section Wound
- Trial name
- NARRCARE (NCT07272252)
- Testing
- 4-step narrative nursing program
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Xi Huang
Depression, Postpartum, Postpartum Depression (PPD)
Brexanolone Lifting Outcomes Of Moms
The purpose of this research study is to test the study drug, LPCN 1154A, as a possible treatment for postpartum depression (PPD).
- Conditions
- Depression, Postpartum, Postpartum Depression (PPD), Post-partum Depression, Postnatal Depression
- Trial name
- BLOOM (NCT07822321)
- Testing
- LPCN 1154A
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- Lipocine Inc.
Depression During Pregnancy, Postpartum Depression (PPD)
Treatment With Repetitive Transcranial Magnetic Stimulation in Peripartal Depression
The goal of this clinical trial is to learn whether repetitive transcranial magnetic stimulation (rTMS) can reduce depressive symptoms in women who are pregnant or up to 12 months after childbirth and have peripartum depression.
- Conditions
- Depression During Pregnancy, Postpartum Depression (PPD), Peripartum Depression
- Trial name
- PPD and rTMS (NCT07774559)
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- 2 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- Psychiatric University Hospital, Zurich
Postpartum Depression (PPD)
Informing Implementation of a Circadian-Focused Intervention for Postpartum Depression
The proposed study is an open-label trial of Re-Timer® wearable morning bright light therapy for postpartum depression. The study is focused on evaluating the feasibility, acceptability, and implementation context of morning…
- Trial name
- NCT07766161
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Postpartum Depression (PPD)
Routine vs. Early Postpartum Depression Screening: A Pragmatic Clinical Trial
After having a baby, some women develop a condition called postpartum depression, or PPD, which can cause sadness, anxiety, and difficulty bonding with their newborn.
- Trial name
- NCT07460063
- Testing
- Early PPD Screening
- Volunteers
- 428 people
- Sponsor
- Massachusetts General Hospital
Perinatal Depression, Postpartum Depression (PPD)
Parents and Babies Pilot
The goal of this study will be piloting the Parents and Babies perinatal depression prevention intervention to examine its feasibility and acceptability and to obtain preliminary data on its efficacy.
- Trial name
- PAB (NCT07607613)
- Testing
- Parents and Babies Virtual Group Intervention, Parents and Babies Hybrid Group Intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Northwestern University
Postpartum Depression (PPD)
A Study of MI078 for Postpartum Depression
This is a multicenter, randomized, double-blind, placebo-controlled trial consisting of an experimental drug group and a placebo group, each enrolling 100 participants.
- Trial name
- NCT07721961
- Testing
- MI078 capsule
- Where
- 36 sites in China
- Volunteers
- 200 people
- Sponsor
- Nanjing Minova Pharmaceutical Co., Ltd.
Parenting Self-efficacy, Postpartum Anxiety
Essential Coaching Postpartum: Evaluating a Parent-focused Postpartum Text Message Program in Nova Scotia
The transition to parenthood is often an exciting yet hard period for parents. In the first year after a new baby, many parents feel less confident, have more anxiety and depression, and feel more isolated and alone.
- Conditions
- Parenting Self-efficacy, Postpartum Anxiety, Postpartum Depression (PPD), Postpartum Stress
- Trial name
- NCT06996067
- Testing
- Essential Coaching Postpartum
- Where
- Canada
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Postpartum Depression (PPD), Perinatal Anxiety
Midwife-led Childbirth Review and Psychological Outcomes in New Parents
The aim of this clinical trial is to support psychological well-being and facilitate adjustment to parenthood among postpartum mothers and fathers through a midwife-led childbirth review (MLCR).
- Conditions
- Postpartum Depression (PPD), Perinatal Anxiety, Postpartum Mental Health
- Trial name
- CROWN (NCT07678801)
- Testing
- Midwife-led childbirth review (MLCR)
- Where
- 2 sites in Czechia
- Volunteers
- 1,300 people
- Sponsor
- Charles University, Czech Republic
Postpartum Depression (PPD), Self-Efficacy
NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE)
The study's objective is to conduct a Phase II randomized controlled trial examining the preliminary efficacy of the VoiceLove app compared to usual care on maternal postpartum depression in mothers with infants admitted to the…
- Conditions
- Postpartum Depression (PPD), Self-Efficacy, Parental Anxiety, Engagement, Patient
- Trial name
- NURTURE (NCT07214597)
- Testing
- VoiceLove mobile phone application
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Postpartum Depression (PPD), Postpartum Anxiety
mHealth Intervention to Prevent Postpartum Depression and Anxiety in Chilean Women (WWWT)
The goal of this clinical trial is to evaluate the effectiveness of a digital psychoeducational intervention, "What Were We Thinking" (WWWT), to prevent the development of postpartum depression and anxiety symptoms in first-time…
- Trial name
- NCT07587177
- Testing
- What Were We Thinking (WWWT) mHealth Intervention
- Volunteers
- 220 people
- Sponsor
- Universidad del Desarrollo
Postpartum Depression (PPD), Labor Analgesia
Maternal Expectations on Labor Analgesia and Risk of Postpartum Depression: An Observational Study
Postpartum Depression (PPD) is defined as the development of depression at any time during the first year after childbirth¹. Its prevalence ranges from 15% to 20%.
- Conditions
- Postpartum Depression (PPD), Labor Analgesia, Expectations
- Trial name
- NCT07292649
- Testing
- Epidural analgesia, Spinal analgesia for labour pain, No neuraxial analgesia
- Where
- Italy
- Volunteers
- 3,640 people
- Sponsor
- University of Padova