Clinical trials: Postprandial
Pharmacokinetics, Metabolism
RI-AME Study OF [ISOTHIAZOLYL-3-14C]-LURASIDONE
This will be an open-label, non-randomized, absorption, metabolism, and excretion study of Lurasidone administered in a suspension at 40 mg to 6 normal healthy male subjects in a postprandial state
- Trial name
- NCT01082146
- Testing
- Lurasidone
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Sumitomo Pharma America, Inc.
Systemic Proinflammatory State
Effect of Eplerenone on Postprandial Inflammatory Response in Healthy Adults
The purpose of this study is to investigate the effect of mineralocorticoid receptor (MR) blockade in healthy participants in a systemic proinflammatory state after a meal high in fat and glucose, which is associated with the…
- Trial name
- NCT01786551
- Testing
- Eplerenone
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Healthy Subjects, Bioavailability
Bioavailability of Oleanolic Acid Formulated as Functional Olive Oil
The oral bioavailability of Oleanolic acid (OA) when formulated as functional olive oil, and its mechanisms of systemic transport, will be approached by mean of randomized and controlled trial with 20 healthy volunteers.
- Trial name
- BIO-OLTRAD (NCT05529953)
- Testing
- Oleanolic acid (CAS no. 598-02-1; PubChem CID 10494), Control commercial olive oil
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Spanish National Research Council
Gastroesophageal Reflux, Dyspepsia
Effects of Diet on Reflux and Dyspepsia
Reflux and dyspeptic symptoms are common affecting 10-20% of the population on a regular basis. Reflux symptoms such as heartburn and regurgitation are caused by the return of acid or non-acid gastric contents into the esophagus.
- Trial name
- NCT02425553
- Testing
- Diet
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Dyslipidemia
Feeding Trial to Determine How Combinations of Different Dietary Bioactive Ingredients Influence High Density Lipoprotein (HDL) Metabolism
This study involves measuring subject's blood lipid responses after they consume a mixture of dietary fats of marine and dairy origin and vitamin supplements mixed into a milkshake, on three separate days.
- Trial name
- HDL (NCT01803594)
- Testing
- Krill Oil, Lutein, Nicotinic acid
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of California, Davis
Cardiovascular Disease
Postprandial Differences After Herring and Beef
While observational studies often find that diets rich in fish reduce the risk of disease, and that diets including a high intake of red meat are associated with increased risk of cardiovascular disease and cancer, the difference…
- Trial name
- NCT02381613
- Testing
- Baked beef, Baked herring, Pickled herring
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Grain-Like Products, Postprandial Glucose
Postprandial Glucose, Insulin and Subjective Saturation Response in Healthy Individuals
This study is a pioneering study in which the effect of the consumption of cakes produced with the addition of cereal-like products such as chia and flax seeds, which have high soluble fiber content, on blood glucose and insulin…
- Conditions
- Grain-Like Products, Postprandial Glucose, Plasma Insulin, Subjective Saturation Response
- Trial name
- NCT05358561
- Testing
- Flaxseed and Chia
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Toros University
Gastroparesis
Cardiac Vagal Effects of GES in Patients With Gastroparesis and Vagal Nerve Action Potentials in Vagus Nerve
The objective of this study is to determine if Gastric Electrical Stimulation may influence vagal outflow via vagal afferent fibers that terminate in the Central Nervous System.
- Trial name
- GES (NCT02159586)
- Testing
- gastric electrical stimulator
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Indiana University
Bioequivalence, Schizophrenia
Study on the Bioequivalence of Amisulpride Orally Disintegrating Tablets in Human Body
The experiment adopts a single center, randomized, open, single dose, two cycle, and double crossover design. The subjects were randomly divided into TR and RT groups.
- Trial name
- NCT06066112
- Testing
- Drug: Test (T) Amisulpride orally disintegrating tablets (200mg). Produced and supplied by Zezheng (Shanghai) Biotechnology Co., Ltd.
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Type 2 Diabetes Mellitus
An Investigational Drug Study in Adults With Type 2 Diabetes on Basal Insulin (MK-0941-006)
A study to assess safety, pharmacokinetics (PK), and pharmacodynamics (PD) of MK-0941 in Type 2 diabetics being treated with basal insulin.
- Trial name
- NCT00511472
- Testing
- MK-0941, LANTUS insulin
- Volunteers
- 70 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2
Beta Cell Relieving and Cardiovascular Protective Effects of LANTUS Treatment in Type 2 Diabetes Patients
The purpose of this phase IV clinical trial is to investigate the effect of Insulin glargine + metformin treatment vs. sulfonylurea + metformin treatment vs. DPP-4 + metformin treatment vs.
- Trial name
- NCT01206712
- Where
- Germany
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- ikfe-CRO GmbH
Healthy
To Test the Effect of Selected Fibres and Flours in Flat Bread on Post-Prandial Blood Glucose and Insulin Responses in Healthy Indian Population
Double-blind, randomized, controlled, cross-over design with 3 test products and one control product. To evaluate the effect of 4 different flour compositions (guar gum 2% and 4%, chickpea flour 15% and barley flour 2% and 5%) of…
- Trial name
- NCT02814357
- Testing
- Control (market standard), wheat flour, chickpea flour
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Drug-induced Weight Gain
Effect of RDX-002 on Postprandial Triglycerides in Subjects Treated With Olanzapine
This Phase 1b Study RDX-002-22-09 has been planned to evaluate the effect of RDX-002 on postprandial triglycerides and ApoB48 levels in normal healthy subjects treated with the atypical antipsychotic drug, olanzapine.
- Trial name
- NCT05857566
- Testing
- RDX-002 + Olanzipine, Olanzapine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Response Pharmaceuticals
Functional Dyspepsia
The Six Food Elimination in Postprandial Distress Syndrome
The six food elimination diet, as known in eosinophilic esophagitis, will be performed in 15 patients with functional dyspepsia (subtype postprandial distress syndrome).
- Trial name
- NCT05651386
- Testing
- Diet
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Metabolic Disorder; Carbohydrate, Absorption, Intestine
Determination of the Postprandial Responses to Two Cereal Foods Differing by Their SDS Content Consumed Alone.
This study aimed at determining the 4-hours postprandial blood glucose and insulin responses to the ingestion of cereal product differing by their SDS content.
- Trial name
- NCT02538653
- Testing
- Sandwich biscuit high in SDS, Co-extruded cereal low in SDS
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mondelēz International, Inc.
Diabetes Mellitus, Type 1
Impact of Meal Composition and Alcohol Consumption on Postprandial Glycemic Control in Subjects With Type 1 Diabetes
Postprandial glucose control is a challenging issue in everyday diabetes care. Indeed, excessive postprandial glucose excursions are the major contributors to plasma glucose (PG) variability in subjects with type 1 diabetes…
- Trial name
- NCT03320993
- Testing
- Mixed meal with different macronutrient composition
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Jorge Bondia
Postprandial Glucose and Insulin Response
Postprandial Effect of High-starch Meals in Individuals With Low and High Copy Number of the Salivary Amylase Gene
Individuals with low copy numbers of salivary amylase gene have lower salivary amylase levels and might therefore have decreased capacity to metabolize starch into glucose.
- Trial name
- NCT03974126
- Testing
- 40 grams of starch, 80 grams of starch
- Where
- Sweden
- Volunteers
- 23 people
- Sponsor
- Lund University
Glucose Metabolism Disorders, Hunger
Ordered Eating and Acute Exercise
There is well documented evidence that ingesting dietary carbohydrate in large amounts tends to increase postprandial glucose. In healthy populations, this is not necessarily a problem, but continuous exposure to high levels of…
- Trial name
- NCT06242015
- Testing
- Carbohydrate-first meal, Carbohydrate-last meal
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Glycemic Response
Assessment of the Glycemic Responses to Nutritional Products (v2.0)
This study assesses the glycemic responses to nutritional products. During a study visit fasted subjects will consume one serving of the reference product or the test product.
- Trial name
- GLIN#2 (NCT05308147)
- Testing
- First Reference product, Second Reference product, Third Reference product
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Post Prandial Inflammation Markers
Study to Investigate the Efficacy of Digestive Enzymes on Inflammation After a Meal
The primary objective of the study is to assess the efficacy of Digestive Enzyme Blend #2, a digestive enzyme dietary supplement product, on markers indicative of inflammation after a meal.
- Trial name
- NCT01729793
- Testing
- Digestive Enzyme #2
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Enzyme Company
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