Clinical trials: Postsurgical Pain
Post-operative Pain, Gynecological Surgery
Acupuncture for Post-Operative Pain Control for Patients Undergoing Gynecological Surgery
This study investigates the role of acupuncture in controlling post-operative pain in patients who have undergone gynecological surgery.
- Conditions
- Post-operative Pain, Gynecological Surgery, Acupuncture
- Trial name
- NCT02855567
- Testing
- Acupuncture needles
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Amputation
Targeted Muscle Reinnervation Study (TMR)
The purpose of this study is to examine the effect of targeted muscle reinnervation on the outcomes of amputees at a level 1 trauma center.
- Trial name
- TMR (NCT05408520)
- Testing
- Targeted Muscle Reinnervation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona
Post Operative Pain, Distal Radius Fracture
Low Dose Dexamethasone for Distal Radius Fractures
The addition of the steroid dexamethasone to a single injection of local anesthetic has been shown to significantly prolong the duration of peripheral nerve blockade compared to local anesthetic alone.
- Trial name
- NCT05274113
- Testing
- Dexamethasone 4mg, Ropivacaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Opioid Use, Opioid Dependence
Efficiency And Quality In Post-Surgical Pain Therapy After Discharge
Following inpatient surgery, more than 80% of patients are prescribed opioids for use after discharge, yet up to 90% of patients report leftover opioids, and only 16% maximize non-opioid therapy.
- Conditions
- Opioid Use, Opioid Dependence, Opioid Misuse, Post-Surgical Complication
- Trial name
- EQUIPPED (NCT05221866)
- Testing
- Empowering Patient to Steer Their Pain Management After Surgery, Provider-facing Prescription Aid
- Where
- United States
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Heated Humidified Carbon Dioxide in Gynaecological Laparoscopic Surgery
Standard Carbon Dioxide Gas Versus Heated Humidified Gas in Gynaecological Laparoscopy
To establish if heated humidified carbon dioxide gas improves pain scores as well as nausea and analgesic requirements in post operative patients compared to standard cold carbon dioxide.
- Trial name
- NCT02319902
- Testing
- Standard cold carbon dioxide gas, Heated humidified carbon dioxide gas
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fevzi Shakir
Pain Management
Effect of Over-the-counter Analgesics on Postoperative Pain
In 2011, a randomized controlled trial compared acetaminophen, acetaminophen + ibuprofen, and acetaminophen + codeine for post-operative pain relief after Mohs surgery.
- Trial name
- NCT06948513
- Testing
- Naproxen, Acetaminophen (Standard of Care), ibuprofen
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zitelli & Brodland Skin Cancer Center
Pain
The Efficacy of Pulsed Electromagnetic Field Therapy for Management of Post-operative Pain Following Cesarean Delivery
Pain following Cesarean delivery remains the most common post-operative complaint, and the provision of effective and safe analgesia is very important.
- Trial name
- NCT01383122
- Testing
- Pulsed electromagnetic field device (ActiPatch TM), Inactive pulsed electromagnetic field device (ActiPatch TM)
- Where
- Canada
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Anesthesia, Endotracheal
Excision Size and Location on the Postoperative Pain After Nevi Excision in Children
The primary purpose of this study is to investigate the effects of excised surface area/body surface area ratio and location of excision on the postoperative pain after nevi excision in children.
- Trial name
- NCT03094754
- Testing
- nevi excision
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Postoperative Pain
Comparison of Two Drugs Bupivacaine and Ropivacaine for Postoperative Analgesia in Bilateral Superficial Cervical Plexus Block After Thyroidectomy
There is significant difference between bupivacaine and ropivacaine in terms of postoperative pain assessment in patients undergoing total thyroidectomy with bilateral superficial cervical plexus block.
- Trial name
- NCT07779551
- Testing
- Group 1 will receive 10ml of 0.25% bupivacaine, Group 2 will receive 10ml of 0.25% ropivacaine on each side.
- Where
- Pakistan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Sargodha Medical College
Other Acute Postoperative Pain
Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal Anesthesia
We conducted a prospective, randomized double-blind study to compare the effectiveness of intravenous paracetamol and dipyrone for preventing pain during early postoperative period in school-age children undergoing lower…
- Trial name
- NCT01858402
- Testing
- Paracetamol, Dipyrone
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baskent University
Root Canal Infection
Evaluation of Post Operative Pain Following Reciprocating and Rotary Heat-treated NiTi Instrumentation of Root Canals: a Randomized Controlled Clinical Trial
The present clinical evaluation was planned for comparing the post-operative pain incidence in maxillary premolar teeth with acute irreversible pulpitis treated by recently introduced heat treated TruNatomy TM and other widely…
- Trial name
- NCT04655105
- Testing
- root canal rotary files
- Where
- India
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Tamil Nadu Dr.M.G.R.Medical University
Procedure, Gynecologic Surgical
Anesthesia on Postoperative Pain After Loop Electrosurgical Excision Procedure
The loop electrosurgical excision procedure (LEEP) is a modified cervical conization that is performed with an electrosurgical loop.
- Trial name
- NCT04984122
- Testing
- LEEP
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Narcotic Use, Renal Transplant Donor of Left Kidney
Postoperative Pain Protocol Limiting Narcotics for Laparoscopic Hand-assisted Donor Nephrectomy
Kidney donors represent healthy patients and their anticipated postoperative course should be uncomplicated and brief. This study looks to optimize the perioperative pain regimen of laparoscopic donor nephrectomy patients by…
- Trial name
- NCT06458842
- Testing
- Ketamine
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Retreatment
Effect of Different Apex Locators on Postoperative Pain in Endodontic Retreatment of Single-Rooted Teeth: Prospective Randomized Clinical Study
Nonsurgical endodontic retreatment is a vital procedure that promotes periapical healing by eliminating previous root canal fillings, necrotic tissue, and residual microorganisms, thanks to the comprehensive cleaning of the root…
- Trial name
- NCT06964490
- Testing
- determination of working length
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ipek Eraslan Akyuz
Postoperative Pain
Efficacy of S(+)-Ketamine Administered as a Continuous Infusion for the Control of Postoperative Pain
Background: The use of low-dose continuous infusion of S(+)-ketamine combined with target-controlled intravenous anesthesia with remifentanil and propofol may be related to the control of postoperative pain and of opioid-induced…
- Trial name
- NCT02421913
- Testing
- S(+)-Ketamine
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Centro Medico Campinas
Crohn's Disease, Inflammatory Bowel Disease
A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Techniques
Postoperative pain can pose significant challenges in the postoperative recovery of patients undergoing major colorectal surgery. Traditionally, opioids have played an important role in treating postoperative pain.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Postoperative Pain
- Trial name
- NCT02538679
- Testing
- US TAP Bupivacaine/Epinephrine, Lap TAP Bupivacaine/Epinephrine
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Root Canal Obturation
Postoperative Pain: Single Cone vs Continuous Wave Compaction Obturation Techniques
The study involves two groups in which root canal obturation will be performed using different obturation techniques. Group one consists of participants with the single cone cold lateral condensation method, while group two…
- Trial name
- NCT07057388
- Testing
- continous wave compaction
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
ACL Injury, Postoperative Pain
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2.
- Trial name
- NCT04246554
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Pain, Postoperative, Periapical; Infection
Clinical and Radiographic Evaluation of Zinc Oxide-Propolis Mixture Versus Modified Triple Antibiotic Paste in LSTR
The aim of this study is to evaluate and compare the clinical effectiveness of zinc oxide-propolis mixture with triple antibiotic paste in LSTR as root canal filling material in necrotic primary molars.
- Trial name
- NCT06158451
- Testing
- Zinc oxide propolis, Modified triple antibiotic paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post-operative Pain, Acute, Opioid Use, Unspecified
Patient Centered Post-Op Pain Management Software Tool Interventional Study Verses Standard of Care
The goal of this clinical trial is to learn if the Pain Coach App will result in less opioids being prescribed to and used by patients undergoing Shoulder/Hip/Knee Arthroplasty surgery while maintaining the same or better pain…
- Conditions
- Post-operative Pain, Acute, Opioid Use, Unspecified, Arthroplasty Complications, Knee Osteoarthritis
- Trial name
- NCT06469177
- Testing
- Pain Coach App
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
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