Clinical trials: Postsurgical Pain
Postoperative Pain
Ropivacaine Transversus Abdominis Plane Blocks for Cesarean Section Analgesia
With this research the investigators hope to determine the lowest dose of ropivacaine used in transversus abdominis plane (TAP) blocks that can effectively treat pain in women after cesarean section (c-section).
- Trial name
- TAPROPI (NCT02893423)
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Postoperative Pain
Pain After PRP Revascularization and Endodontic Treatment of Non-vital Mandibular Molars With Apical Periodontitis
randomized clinical trial which Evaluate thr Post-operative Pain Following Platelet Rich Plasma (PRP) Revascularization versus Conventional Endodontic Treatment of Non-vital Mature Mandibular Molars with Chronic Peri-apical…
- Trial name
- NCT03350841
- Testing
- Platelet rich plasma PRP, root canal treatment
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative, Endodontically Treated Teeth
Postoperative Pain Intensity Associated With the Use of Different Nickel Titanium Instrumentation Systems
In this study the effect of different engine-driven nickel titanium (Ni-Ti) instrumentation systems (OneShape, Revo S and WaveOne) on postoperative dental pain in patients with asymptomatic teeth after a single-appointment root…
- Trial name
- NCT03478241
- Testing
- Group 1: single file rotary motion, Group 2: multiple file rotary motion, Group 3: single file reciprocal motion
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Drug Usage
Gabapentin as Adjunctive Treatment for Postoperative Pain Control
The specific aims of this research study are to use 600 mg gabapentin as an adjunctive treatment for acute postoperative pain control in order to reduce postoperative opiate consumption and improve postoperative pain control.
- Trial name
- NCT02490345
- Testing
- gabapentin
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Indiana University
Fractures, Closed, Humeral Fractures
Regional Blocks for Lateral Condyle Fractures
The purpose of this study is to investigate the post-operative pain control in pediatric patients with closed lateral condyle fractures who undergo open reduction and percutaneous pinning.
- Conditions
- Fractures, Closed, Humeral Fractures, Pain
- Trial name
- NCT03796572
- Testing
- Ropivacaine, Puncture Wound and Dressing
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Post Operative Pain, Preemptive Analgesia
Paracetamol Plus Tramadol Versus Fentanyl in Day Case Surgeries
Postoperative pain is an important problem, especially for day case surgeries. It has negative effects on patient's hemodynamics and can cause delayed ambulation resulting in prolonged duration of hospital stay and poor patient…
- Trial name
- NCT05990686
- Testing
- tramadol plus paracetamol, Fentanyl Injection
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Post Operative Pain
Evaluation of Post Operative Pain After Sonic Activation and Different Irrigation Needles During Root Canal Treatment
The study compares the post operative pain after root canal therapy, after using different irrigation protocols. The subjects are divided into 3 groups and different irrigation protocol is used in each group.
- Trial name
- Endoactivator (NCT05840783)
- Testing
- Open ended needle irrigation, side vented needle irrigation, Sonic activation
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Temporomandibular Joint Disorders
The Effect of Piroxicam Addition During Arthrocentesis on Mouth Opening and Postoperative Pain
TMDs is an ancient condition discovered thousands of years ago. Historians state that the ancient Egyptians were the first who managed TMDs. They manually treated joint dislocation by away similar to ours nowadays.
- Trial name
- NCT06508203
- Testing
- arthrocentesis with lactate ringer only, arthrocentesis with lactate ringer followed by injection with piroxicam 2 ml (40mg)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Reduced Corneal Sensation
Effect of Superficial Keratotomy on Reducing Postoperative Pain Fallowing Conjuctival Flap
During conjunctival flap surgery the corneal epithelium is removed and a conjunctival flap is placed on the cornea and after a few weeks the conjunctiva covers the surface of the eye.
- Trial name
- NCT05494931
- Testing
- corneal neurotomy
- Where
- Iran
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Iran University of Medical Sciences
Ambulatory Hand Surgery
Patient Education and Use of Post Operative Pain Medication in Ambulatory Hand Surgery: a Randomized Controlled Trial
There is a current opioid epidemic in the United States partially fueled by excess prescribing practices after surgery. The objective of this study is to decrease the amount of opioids needed after ambulatory hand surgery.
- Trial name
- NCT03219177
- Testing
- Patient education regarding indications for opioid use and side effects of opioid use after hand surgery, Standard of care post-operative counseling
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Postoperative Pain Management, Open-heart Surgery
Erector Spinae Plane Block and Postoperative Recovery After Open-Heart Surgery
This prospective randomized controlled clinical trial evaluated the effects of bilateral erector spinae plane block (ESPB) on postoperative systemic functions in adult patients undergoing elective open-heart surgery via median…
- Conditions
- Postoperative Pain Management, Open-heart Surgery, Median Sternotomy, Erector Spinae Plane Block
- Trial name
- ESPB-SYSHEART (NCT07259057)
- Testing
- Erector spinae plane block (ESPB), Intravenous Opioid Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Pain
Analgesic Effects Of Dexamethasone; Its Use To Reduce Post Operative Pain Scores
A randomised controlled clinical trial to assess the effect of intraoperative dexamethasone on the 24 hour post operative pain scores of adult patients in Mulago hospital undergoing mastectomies, laparotomies and thyroidectomies.
- Trial name
- DOPP (NCT02372812)
- Testing
- dexamethasone
- Where
- Uganda
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Makerere University
Arthroscopic Shoulder Surgery, Pain, Postoperative
Examining the Effectiveness of a Connective Tissue Matrix Implant in Reducing Post-operative Pain and Narcotic After Outpatient Arthroscopic Shoulder Surgery
This document is a protocol for a human research study. This study is to be conducted according to United States standards of Good Clinical Practice in accordance with applicable Federal regulations and institutional research…
- Trial name
- ECM (NCT04633837)
- Testing
- Extracellular Matrix Graft Injectable Implant
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brian Badman
Hyperhidrosis
Study to Assess the Efficacy of Botulinum Toxin B (Myobloc) for the Treatment of Prosthesis-associated Sweating
The objective of this study is to determine if Myobloc significantly decreases prosthesis-associated symptomatic sweating in amputees when compared to a saline solution placebo.
- Trial name
- NCT01671800
- Testing
- Botulinum Type B
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Pain, Postoperative
Comparison of AI-Generated Pain Scoring Visuals With Visual Analog Scale (VAS) for Pain Assessment
This prospective study will be conducted in surgical wards, assessing postoperative patients. Initially, patients will be evaluated using the VAS method.
- Trial name
- NCT06456853
- Testing
- Pain assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Endodontically Treated Teeth
Postoperative Pain After İntracanal Procedures
Aim: The aim of this study is to investigate the effects of different irrigation activation systems on pain after endodontic treatment in molar teeth with irreversible pulpitis.Post-operative pain values of the participants will…
- Trial name
- NCT04892355
- Testing
- Root canal irrigation
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Stress Urinary Incontinence, Postsurgical Pain
The Follow-up After Shorter Tapes Study. Effectiveness and Safety of Shorter Trans-obturator Tapes.
Urinary incontinence after pregnancy and labor affects 1 in 3 women and has a negative impact on quality of life (QOL), limiting women's physical activity and impairing sexual function.
- Conditions
- Stress Urinary Incontinence, Postsurgical Pain, Follow-Up Studies
- Trial name
- FAST (NCT06731985)
- Where
- Norway
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Hysterectomy, Myomectomy
Effect of Perioperative iv Dexmedetomidine vs. Lidocaine on Postoperative Pain, Analgesic Consumption and Recovery After Abdominal Gynaecological Surgery
Postoperative pain continues to be inadequately managed and is the most common reason for the delay in discharge and unplanned hospital admission after surgery. Opioids remain the mainstay for postoperative analgesia.
- Trial name
- NCT03363425
- Testing
- Lidocaine Iv, Dexmedetomidine, Normal saline
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Athens
Postoperative Pain, Postoperative Nausea and Vomiting
Effect of Steroids on Post-tonsillectomy Morbidities
This study aims to evaluate the effect of postoperative systemic rapid onset and short acting dexamethasone followed by a tapering dose of oral prednisolone on post-tonsillectomy morbidities.
- Trial name
- NCT02401529
- Testing
- IV dexamethasone, Oral prednisolone, Paracetamol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Fahd General Hospital
Pain, Postoperative
PREEMPTİVE PARA-CERVİCAL BLOCK FOR POSTOPERATİVE PAIN AFTER LAPAROSCOPIC HYSTERECTOMY
Total hysterectomy is one of the most common surgical procedure in gynecology. The laparoscopic route for the performance of hysterectomies are on the rise [1].
- Trial name
- NCT05341869
- Testing
- Para-cervical block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.