Clinical trials: Posttraumatic Stress Disorder, completed
Stress Disorders, Post-Traumatic
Study To Evaluate The Efficacy And Safety Of Balovaptan In Adults With Post-Traumatic Stress Disorder (PTSD)
This study will evaluate the efficacy and safety of 10 mg of oral administration balovaptan once a day (QD) compared with matching placebo in adults with PTSD.
- Trial name
- NCT05401565
- Testing
- Balovaptan
- Where
- 15 sites in United States
- Volunteers
- 29 people
- Sponsor
- Hoffmann-La Roche
PTSD, Depression
Vilazodone for the Treatment of Posttraumatic Stress Disorder
The purpose of this study is to determine whether vilazodone is effective in the treatmen of Posttraumatic Stress Disorder (PTSD)and co-morbid mild or more depression.
- Trial name
- NCT01715519
- Testing
- Treatment (Viibryd)
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Southern California Institute for Research and Education
Mild Traumatic Brain Injury, Post Traumatic Stress Disorder
Biological Signatures, Probiotic Among Those With mTBI and PTSD
Exaggerated inflammation in the body and brain is thought to play a role in the vulnerability to and aggravation and perpetuation of adverse consequences among those with co-occurring mild TBI (mTBI) and post-traumatic stress…
- Trial name
- NCT02723344
- Testing
- of Lactobacillus reuteri (L. reuteri; DSM 17938), Sunflower and medium chain triglyceride oils
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- VA Office of Research and Development
Trauma, Posttraumatic Stress Disorder
Tachikawa Project for Prevention of Posttraumatic Stress Disorder With Polyunsaturated Fatty Acid (TPOP): TPOP-02 Study
The purpose of this study is to evaluate efficacy and safety of Polyunsaturated Fatty Acid for the prevention of Posttraumatic Stress Disorder (PTSD) in patients with accidental injuries.
- Trial name
- NCT00671099
- Testing
- Omega-3 Polyunsaturated Fatty Acid
- Where
- Japan
- Volunteers
- 110 people
- Sponsor
- Japan Science and Technology Agency
PTSD
Brief Treatment for Posttraumatic Stress Disorder
The primary goal of this study is to examine whether a brief treatment approach for PTSD is equally efficacious in the treatment of active duty service members relative to a first line treatment approach that requires much…
- Trial name
- NCT03033602
- Testing
- written exposure therapy, CPT, cognitive only
- Where
- 2 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Boston VA Research Institute, Inc.
PostTraumatic Stress Disorder, Eating Disorder
Integrated Treatment for Co-occurring Eating Disorders and Posttraumatic Stress Disorder
Although psychotherapy for eating disorders (EDs) can be effective, approximately 50% of those who complete a course of the best available therapy continue to have significant ED symptoms at the end of treatment.
- Trial name
- NCT03502564
- Testing
- CBT for ED, Concurrent CBT for ED and PTSD
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- University Health Network, Toronto
Mild Traumatic Brain Injury
Remediation of Impaired Self-Regulation in Patients With Mild TBI
The ability to regulate impulses enables us to plan for the future, to maintain focus in the face of distractions (i.e. to encode memories), and to manage emotions.
- Trial name
- NCT02260570
- Testing
- Tolcapone
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Complex Post-Traumatic Stress Disorder
Patient-centered Modular CBT for CPTSD: A Randomised Controlled Pilot Study
Modular Patient Centred CBT (MPC) for Complex PTSD (CPTSD) is a manualized psychotherapy programme that consists of five treatment modules addressing 1) Affect dysregulation, 2) Disturbed relationships, 3) Negative self-concept…
- Trial name
- PACE pilot RCT (NCT05259592)
- Testing
- Psychotherapy
- Where
- 5 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Danish Veterans Centre
PTSD
Post-Traumatic Stress Disorder (PTSD) Symptom Study
The primary goals for this investigation are to quantify: (1) fluctuations in PTSD symptom reports when assessed at bi-weekly intervals; (2) change in PTSD symptoms associated with stressful life events; and (3) change in PTSD…
- Trial name
- NCT00018798
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Schizophrenia, Bipolar Disorder
Mobile Self-Tracking of Mental Health
Serious mental illnesses require years of monitoring and adjustments in treatment. Stress, substance abuse or reduced medication adherence cause rapid worsening of symptoms, with consequences that include job loss, homelessness…
- Conditions
- Schizophrenia, Bipolar Disorder, Schizoaffective Disorder, Post-traumatic Stress Disorder
- Trial name
- NCT05023252
- Testing
- mobile application
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
An RCT of a Primary Care-Based PTSD Intervention: Clinician-Supported PTSD Coach
Posttraumatic Stress Disorder (PTSD) is an often severe and frequently disabling condition. It is associated with compromised health, early mortality, and substantial economic costs.
- Trial name
- NCT02685358
- Testing
- Clinician-Supported PTSD Coach, Primary Care Mental Health Integrated Care as Usual
- Where
- 2 sites in United States
- Volunteers
- 234 people
- Sponsor
- VA Office of Research and Development
Fibromyalgia Syndrome, Posttraumatic Stress Disorder
Impact of Post-Traumatic Stress Disorder Treatment by Reconsolidation Therapy on Fibromyalgia Syndrome
The aim of the study is to demonstrate a significant improvement in quality of life specific to patients with fibromyalgia syndrome in patients with fibromyalgia syndrome with comorbid posttraumatic stress disorder, treated with…
- Trial name
- PTSD-FMS (NCT04950426)
- Testing
- Propranolol
- Where
- 2 sites in France
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Henri Laborit
Substance Use Disorders, Posttraumatic Stress Disorder
Post-traumatic Stress Disorder (PTSD), Addiction, and Virtual Reality
Eligible veterans, National Guardsmen \& Reservists with post-traumatic stress disorder (PTSD) and problems with addiction will be randomly assigned to one of two treatment conditions.
- Trial name
- NCT01186315
- Testing
- Prolonged Exposure Therapy, Prolonged Exposure therapy + VR/ER
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Duke University
Post Traumatic Stress Disorder
Autobiographical Memory Flexibility Training (MemFlex) for Posttraumatic Stress Disorder
The experience of trauma not only impacts the way an individual thinks and feels, but can also produce changes in the way someone remembers their personal past.
- Trial name
- NCT03634709
- Testing
- Memory Flexibility training (MemFlex)
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Respiratory Failure, SARS-CoV 2
Stress Related Disorders in Family Members of COVID-19 Patients Admitted to the ICU
Coronavirus disease 2019 (COVID-19) is a novel infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Conditions
- Respiratory Failure, SARS-CoV 2, Corona Virus Infection, Post Intensive Care Unit Syndrome
- Trial name
- NCT04476914
- Where
- 9 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Generalized Anxiety, Stress Disorder, Posttraumatic
CBT for Anxiety Sensitivity vs. Disorder-specific CBT: An RCT
Adults with high anxiety sensitivity (AS) and a mental health diagnosis of anxiety, depression, or posttraumatic stress will be recruited and will be randomly assigned to either transdiagnostic cognitive behavioural therapy (CBT)…
- Conditions
- Generalized Anxiety, Stress Disorder, Posttraumatic, Social Anxiety, Major Depression
- Trial name
- NCT03015285
- Testing
- Cognitive Behavioural Therapy
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
PTSD
Intranasal Insulin for Posttraumatic Stress Disorder
To evaluate if intranasal insulin is effective in reducing PTSD symptoms.
- Trial name
- NCT04044534
- Testing
- Intranasal insulin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- VA Connecticut Healthcare System
Traumatic Brain Injury, Posttraumatic Stress Disorder
Neural Markers and Rehabilitation of Executive Functioning in Veterans With Traumatic Brain Injury and Posttraumatic Stress Disorder
Up to half of all military service members with combat-related traumatic brain injury (TBI) also suffer from Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT01410721
- Testing
- Cognitive Rehabilitation Intervention, Cognitive Rehabilitation Control Intervention
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- University of North Carolina, Chapel Hill
Post Intensive Care Syndrome, Anxiety
Sensation Awareness Focused Training for Spouses
The purpose of the feasibility study is prevention of Post Intensive Care Syndrome in Family (PICS-F), specifically in spouses of critically ill, mechanically ventilated patients, using a nonpharmacological intervention called…
- Conditions
- Post Intensive Care Syndrome, Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- SAF-T (NCT03129204)
- Testing
- SAF-T
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Trauma, Psychological, Post Traumatic Stress Disorder
Motor Interference Therapy For Traumatic Memories
The aim of the study is to compare the effect of motor interference therapy (TIM) to reduce the intensity of discomfort (distress) generated by a traumatic memory compared to a relaxation control maneuver, immediately after the…
- Trial name
- TIMCO (NCT03627078)
- Testing
- motor interference therapy, Relaxation exercises
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
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