Clinical trials: Pre Diabetic
Pre Diabetes
The Effect of Nutrient Sequencing in Healthy Adults
There is emerging evidence that the order in which food is consumed in a meal, known as the "nutrient sequence", can have protective health effects against obesity and metabolic disease.
- Trial name
- NCT07873437
- Testing
- Finger Prick- Blood Glucose, Whole Blood Draw, Diet History Questionnaire
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cornell University
PreDiabetes, Circadian Dysregulation
Morning Light Treatment to Improve Glucose Metabolism
The primary purpose of this pilot study is to test a novel head worn light device (Re-Timer®) as an intervention to improve glucose metabolism in people with prediabetes.
- Trial name
- ML (NCT03188263)
- Testing
- Bright Light, Dim Light
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Overweight and Obesity
The Effect of Extended Use of the EPITOMEE CAPSULE (ELECT)
The Effect of Extended Use of the Epitomee Capsule on BodyWeight in subjects with Overweight and Obesity with and without Prediabetes
- Trial name
- NCT04994769
- Testing
- Epitomee Capsule
- Where
- 3 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Epitomee medical
Type 2 Diabetes, PreDiabetes
Recreational Basketball to Increase Participation in Diabetes Prevention
The purpose of this study is to assess the efficacy of adapting the National Diabetes Prevention Program (NDPP) to include recreational sports in effort to increase physical activity (PA) and promote lifestyle changes that can…
- Trial name
- DPPHoops (NCT05066542)
- Testing
- NDPP + Basketball (BB), NDPP Standard of Care SOC
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Prediabetes
Time to Healthy Lifestyle Habit Using Digital Health Tools in Adults at Risk of Diabetes
1. Background \& Context The Challenge: Type 2 Diabetes (T2D) is a major public health burden. Lifestyle changes are effective, but little is known about how long it actually takes to make these changes stick.
- Trial name
- NCT07667361
- Testing
- Hybrid digital intervention with personalized support., Standard lifestyle education
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Prediabetes
Training Induced Muscle-Adipose EV Communication
This study examines how muscle cells communicate with fat cells through tiny packages called extracellular vesicles (EV) during exercise.
- Trial name
- TIMER2 (NCT07106450)
- Testing
- Acute Resistance Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yuan Wen
Obesity, Metabolic Syndrome
Time Restricted Feeding to Reduce Weight and Cardiometabolic Risk
The obesity rate in Malaysia is higher than the average world obesity rate. Central obesity is a component of metabolic syndrome (MetS) which is also made up of dyslipidemia, impaired glucose tolerance, and hypertension.
- Conditions
- Obesity, Metabolic Syndrome, Pre Diabetes
- Trial name
- NCT04243746
- Testing
- Time Restricted Feeding, Standard Care
- Where
- Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- RCSI & UCD Malaysia Campus
Diabetes Mellitus, Type 2, Insulin Resistance
Exercise to Restore 24h Rhythms in Metabolism
This study will investigate the effect of exercise training on 24h rhythms in substrate metabolism in overweight subjects with impaired glucose tolerance. Subjects will perform exercise training for 12 weeks.
- Trial name
- RESTORE (NCT04565418)
- Testing
- High-intensity interval training
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Diabetes Prevention
Diabetes Prevention Program Pilot Study
This pilot study is intended to demonstrate that we can actually deliver the Diabetes Prevention Program intervention well and to show that it is likely effective.
- Trial name
- DPP (NCT00729079)
- Testing
- DPP
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rochester
PreDiabetes
The Effects of Tai Chi and Pilates for Individuals With Prediabetes
The purpose of this study; To investigate the effects of Clinical Pilates and Tai Chi exercises on glycemic control, body composition, balance function and physical activity level in individuals with prediabetes.
- Trial name
- NCT06343025
- Testing
- Pilates Exercises Group, Tai Chi Exercises Group
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Prediabetes, Diabetes Type 1
An Exploratory Clinical Trial to Generate Whole Blood Samples for Analysing Genetic Polymorphisms
G (guanine nucleotide binding) proteins associating with G protein-coupled receptors (GPCR) are key players in the pathogenesis of obesity and diabetes and are targets of pharmacotherapeutic inter-ventions.
- Conditions
- Prediabetes, Diabetes Type 1, Diabetes Type 2
- Trial name
- NCT02057497
- Volunteers
- healthy volunteers welcome
- Sponsor
- Profil Institut für Stoffwechselforschung GmbH
Morbid Obesity, Metabolic Syndrome
FMT in Obesity: RYGB vs. LEAN vs. Autologous FMT
This double-blinded proof-of-concept study is proposed to explore the effects of fecal microbiota transfer (FMT) in human subjects.
- Conditions
- Morbid Obesity, Metabolic Syndrome, Diabetes, PreDiabetes
- Trial name
- DACH (NCT06268990)
- Testing
- Fecal microbiota transplantation
- Where
- Austria
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Wiebke Kristin Fenske
Diabetes Mellitus, Impaired Fasting Glucose
Effect of Red Blood Cell Survival on a Commonly Used Diabetes Lab Test-HbA1c
Prevention of complications in veterans with diabetes depends heavily on assessment of blood glucose and HbA1c. The HbA1c is a blood test that measures the exposure of hemoglobin (Hb) to a person's average blood glucose over the…
- Conditions
- Diabetes Mellitus, Impaired Fasting Glucose, Prediabetes
- Trial name
- NCT01204216
- Testing
- re-infusion of biotin labeled cells, Diabetes education/diabetes medication adjustment
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Isolated Impaired Fasting Glucose
Low-calorie Diet in Isolated Impaired Fasting Glucose
This study aims to evaluate the preliminary efficacy of a low-calorie diet (LCD) intervention in addressing the underlying pathophysiological abnormalities and improving fasting hyperglycemia among individuals with isolated…
- Trial name
- NCT06451055
- Testing
- Low-calorie diet, Routine dietary and physical activity habits
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Diabetes (DM), Pre Diabetes
FastForward: A Prospective Analysis of Long-term Fasting and Subsequent Food Reintroduction in Humans
This study explores what happens in the body and wellbeing during and after a period of long-term fasting. At the Buchinger Wilhelmi Clinic, participants follow a medically supervised fasting program lasting five or more days…
- Conditions
- Diabetes (DM), Pre Diabetes, Overweight (BMI > 25)
- Trial name
- FastForward (NCT07155993)
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Buchinger Wilhelmi Development & Holding GmbH
Pre-diabetes, Obesity
Sub-Study of the PREVIEW Study Australia
The aim of this study is to investigate possible enduring effects of a standard 2-month weight loss program on appetite regulation, bone homeostasis and muscle strength in younger and older adults, as well as the impact of…
- Trial name
- NCT02030249
- Testing
- Low calorie diet administered from 0 to 2 months, High Protein / Low Glycaemic Index, Moderate Protein / High Glycaemic Index
- Where
- 3 sites in Australia
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Obesity, Hyperlipidemia
Translating a Heart Disease Lifestyle Intervention Into the Community
Translating a Heart Disease Lifestyle Intervention in the Community study will evaluate the feasibility and initial effectiveness of a community-based, culturally-targeted, lifestyle intervention to improve the cardiovascular…
- Conditions
- Obesity, Hyperlipidemia, Hypertension, Pre-diabetes
- Trial name
- NCT01647438
- Testing
- Lifestyle Intervention, Print Health Education
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Obesity, Gestational Diabetes
Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics
The primary objective of the STRIVE study is to compare two implementation strategies for Diabetes Prevention Program delivery: an in-person health coach strategy (standard 24 in-person sessions at WIC clinics) vs.
- Conditions
- Obesity, Gestational Diabetes, Lifestyle, Healthy, Glucose Intolerance During Pregnancy
- Trial name
- STRIVE (NCT06116149)
- Testing
- In-person health coach delivery of the GLB, Technology-assisted health coach delivery of the GLB
- Where
- United States
- Volunteers
- 722 people, healthy volunteers welcome
- Sponsor
- Tulane University
Pre-diabetes, Pre-hypertension
Primary Prevention of Cardiovascular Disease (CVD) in Pre-diabetic & Pre-hypertensive Subjects
The purpose of this study is to determine whether treating pre-diabetic \& pre-hypertensive individuals using multiple drugs intervention (anti-hypertensive drugs (i.e., ACEI) plus anti-glycemic drug (i.e., metformin) plus…
- Trial name
- PPCVD (NCT01364675)
- Testing
- Metformin+Enalapril+Simvastatin
- Where
- Thailand
- Volunteers
- 8,900 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Prediabetic State (IGT), Prediabetic State
Intestinal Endotoxemia and Beta- Cell Dysfunction in Prediabetics
the goal of this observation study is to learn about association between intestinal endotoxemia and prediabetes lean patients with the aim of prevention of diabetes in those category of patients
- Trial name
- NCT07557329
- Testing
- hba1c, lbp, fasting blood sugar, lipogram, fastinf insulin
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sohag University