Clinical trials: Pre Diabetic
PreDiabetes, Diabetes Mellitus, Type 2
Chronotype, Chrononutrition and Glucose Tolerance Among Prediabetic Individuals
Chronotype and chrononutrition, both are emerging research fields in nutritional epidemiology. However, its association with glycemic control in the global population is less clear.
- Trial name
- NCT05163964
- Testing
- Lifestyle Intervention
- Where
- 11 sites in Malaysia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universiti Tunku Abdul Rahman
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Variation of Genes Controlling Carbohydrate and Lipid Metabolism
Aim of the study is to investigate genes regulating glucose and lipid metabolism in subjects whose glucose metabolism, lipid metabolism, blood flow, or body fat distribution has been measured using positron emission tomography…
- Conditions
- Diabetes Mellitus, Type 2, Cardiovascular Diseases, Obesity, Insulin Resistance
- Trial name
- CMgene (NCT03310502)
- Where
- Finland
- Volunteers
- 2,050 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Diabetes Mellitus, Type 2, Pre Diabetes
Mobile Application to Create Healthy Food Preparation Habits for Patients With Diabetes and Prediabetes
Boston Medical Center (BMC) serves many underserved, low-income patients and has developed an innovative strategy to combat food insecurity including a preventative food pantry, a teaching kitchen, and a rooftop farm that…
- Trial name
- NCT05726409
- Testing
- Mobile application
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Diabetes Mellitus, Type 2, PreDiabetes
18F-FDOPA PET/CT Imaging in Patients Undergoing Metabolic Surgery
The aim of the study is to compare the endocrine function of pancreas between pre and post metabolic surgery in patients with type 2 diabetes or prediabetes.
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Obesity
- Trial name
- NCT03821961
- Testing
- Metabolic Surgery
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Pre Diabetes
Glucose and Glycogen Dynamics in Prediabetes
The goal of this observational study is to investigate changes in nocturnal and postprandial glucose and glycogen metabolism in individuals with impaired fasting glucose and impaired glucose tolerance compared to healthy…
- Trial name
- GGD (NCT06317142)
- Testing
- Acipimox 250 mg Oral Capsule
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Hyperglycemias, Prediabetes
Efficacy of the pA1c®HI Postbiotic in Metabolic Regulation in Healthy Individuals With Hyperglycemia
This study will evaluate the effects of pA1c®HI, a heat-inactivated postbiotic derived from the bacterium Pediococcus acidilactici, on blood glucose regulation and other aspects of metabolic health in adults with elevated blood…
- Trial name
- CR2027 (NCT07903870)
- Testing
- Postbiotic
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genbioma Aplicaciones SL
CKD Progression
Hyperuricemia as Early Indication of CKD Progressing in Prediabetic
Chronic kidney disease (CKD) is a major global health problem, and hyperuricemia has emerged as both a consequence and a potential driver of its progression.
- Trial name
- NCT07199205
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
PreDiabetes
Investigation of Nutrilite Glucose Health Herbal Drink on Prediabetes Persons
The goal of this two arms, randomized, double-blind controlled trial is to study whether Nutrilite herbal drink could ameliorate blood glucose level in prediabetes population.
- Trial name
- NCT07690735
- Testing
- Nutrilite Glucose health herbal drink
- Where
- China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Amway (China) R&D Center
Pre Diabetes
BRInging the Diabetes Prevention Program to GEriatric Populations
Over 24 million Americans are over 65 years and have prediabetes. Prediabetes can be addressed using a public health approach: among the 20% of participants in the Diabetes Prevention Program (DPP) who were ages 60 and over, the…
- Trial name
- BRIDGE (NCT05166785)
- Testing
- DPP Tailored for Older Adults and delivered via Telehealth, In-Person Diabetes Prevention Program (DPP)
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Pre-diabetes
High Protein Diet on Transcriptomic, Metabolomics, Hepatic and Pancreatic Fat Anatomy and Physiology in Asian Indians With Pre-diabetes
Diabetes/ prediabetes is a substantial problem in India not only because it itself can be associated with morbidities such as coronary artery disease but also because it is a point of importance for the prevention of other…
- Trial name
- NCT05925933
- Testing
- Intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
PreDiabetes
2-A-Day Study: Twice a Day Meals Study.
Caloric restriction increases lifespan and/or healthspan across multiple species. However implementation of long-term CR in humans is problematic and unacceptable to many individuals.
- Trial name
- NCT03809299
- Testing
- Ad libitum meal timing, Twice a day meals
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Obesity, Prediabetes
Effects of a GLP-1 Formula Drink on Gut Microbiota and Glycemic Control in Prediabetic Individuals
A clinical human dietary intervention trial was conducted to investigate the effects of GLP-1 FORMUL liquid supplementation in individuals with prediabetes or obesity, with a focus on improvements in glycemic and lipid…
- Trial name
- NCT07089732
- Testing
- GLP-1 formula liquid drink
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Occupational Stress, Gender Related Stress
Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker Women
The goal of this hybrid Type 1 effectiveness-implementation trial is to test the extent to which a peer support and community resource navigation intervention improves psychological well-being, addresses non-biologic drivers of…
- Conditions
- Occupational Stress, Gender Related Stress, Social Isolation, Hypertension
- Trial name
- NCT07111026
- Testing
- Sisters for Heart Health, Basic intervention
- Where
- United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Emory University
PreDiabetes, Overweight and Obesity
Effect of Dairy Product Matrices on Insulin Resistance in People with Overweight and Obesity and Prediabetes
The objective of the study is to determine the effect of dairy product matrices on insulin sensitivity in overweight and obese adults with prediabetes. Females and males (30-65 y) will be recruited from the greater Montreal area.
- Trial name
- NCT06322940
- Testing
- 250 mL serving size, 3.25% fat content, 175 g serving size, ≥2% fat content, 50 g serving size, ≥28% fat content
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
PreDiabetes, Overweight and Obesity
Family Diabetes Prevention Program Pilot Study
This study will examine the feasibility and acceptability of a family-oriented augmentation of the Diabetes Prevention Program lifestyle intervention (DPP), called the Family DPP.
- Conditions
- PreDiabetes, Overweight and Obesity, Type 2 Diabetes, Overweight, Childhood
- Trial name
- NCT05358444
- Testing
- National Diabetes Prevention Program Lifestyle Intervention (DPP), Family Diabetes Prevention Program (Family DPP)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Prediabetic State, Insulin Resistance
Macronutrient Effects on Alzheimer's Disease (MEAL-2)
This study compares the effects of a one-month diet high in saturated fat (SF), glycemic index (GI), and salt (Na+) to a diet low in these nutritional parameters on memory and other cognitive functions, on MRI measures of brain…
- Conditions
- Prediabetic State, Insulin Resistance, Middle Age, Prehypertension
- Trial name
- MEAL-2 (NCT02463084)
- Testing
- Low Diet, High Diet
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
PreDiabetes
Effect of Oral Supplementation With Curcumin on Insulin Sensitivity in Subjects With Prediabetes
This study evaluates the effects of oral supplementation with curcumin on the insulin sensitivity in subjects with prediabetes. The half of participants will receive curcumin and bioperine in combination, while the other half…
- Trial name
- NCT03917784
- Testing
- Curcumin, Starch
- Where
- Mexico
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Hospital General de México Dr. Eduardo Liceaga
Poor Glycemic Control, Cardiovascular Risk Factors
The Potential of Carnosine Supplementation in Optimising Cardiometabolic Health
The investigators hypothesise that carnosine supplementation will improve: 1. glycaemic control 2. cardiovascular risk factors 3.
- Conditions
- Poor Glycemic Control, Cardiovascular Risk Factors, Cognitive Function 1, Social
- Trial name
- NCT02917928
- Testing
- carnosine
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Monash University
Pre Diabetes
Evaluation of an Automated Physician-Directed Messaging on Patient Engagement in the Digital Diabetes Prevention Program
This study aims to understand the effects of automated physician directed messaging on patient engagement in the digital diabetes prevention program (dDPP).
- Trial name
- NCT04773834
- Testing
- Digital diabetes prevention program (dDPP), Adapted dDPP-EHR tool
- Where
- United States
- Volunteers
- 551 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Type 2 Diabetes, Muscular Atrophy
Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes
The purpose of this research is to gather data on how exercise can help recovery of muscle mass, strength, and physical function after bedrest in older adults with pre-diabetes and type 2 diabetes.
- Conditions
- Type 2 Diabetes, Muscular Atrophy, Sedentary Behavior, Exercise
- Trial name
- RECOVER (NCT04057677)
- Testing
- Bed Rest Intervention, Exercise Program
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute