Clinical trials: Pre- Frail
Frailty in Older Adults
Chair-bound Exergaming in Pre-frail/ Frail Older Adults in Nursing Home
This pilot randomized controlled trial is designed to investigate the effectiveness of chair-bound exergaming on improving physical and cognitive function in pre-frail/ frail nursing home residents
- Trial name
- NCT06849557
- Testing
- Exergaming
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Hong Kong Metropolitan University
Fragility
Exercise Intervention to Reverse Frailty
The objective of this study is to evaluate a multi-component exercise intervention as an effective therapy to reverse pre-frailty phenotype in females age 65 or older.
- Trial name
- ERF (NCT02952443)
- Testing
- Exercise, Control
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Frailty Syndrome, Pre-frail Older Adults
Targeted Physical Function Exercises on Frailty and Falls Management in Pre-Frail Community-Dwelling Older Adults
The investigators will conduct a randomized controlled trial to assess the impact of targeted physical function exercises on frailty and falls in community-dwelling adults over 65 years of age.
- Trial name
- NCT06731712
- Testing
- Physical Function Exercises
- Where
- Greece
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Hellenic Mediterranean University
Pre-frail Elderly, Frail Elderly
Dose Finding Study in Physically Frail Elderly to Measure 25(OH) Vitamin D Levels After Supplementation With Hy.D Calcifediol 25 SD/S and Vitamin D3
The purpose of this study is to assess the dose of Hy.D Calcifediol 25 SD/S (a metabolite of vitamin D3) which will achieve the range of mean serum 25(OH)D between 75-100nmol/L in physically frail elderly people after 24 weeks of…
- Trial name
- D-DOSE (NCT01868945)
- Testing
- 5 µg/day Hy.D Calcifediol, 10 µg/day Hy.D Calcifediol, 15 µg/day Hy.D Calcifediol
- Where
- Netherlands
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Health Services for the Aged
Multicomponent Exercise on Executive Function and Balance
The present study is to examine the effects of a multicomponent exercise on executive function and balance in pre-frail older adults.
- Trial name
- NCT03611192
- Testing
- Multicomponent exercise, Home-program exercise
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Yang Ming Chiao Tung University
Frail Elderly, Dual Task Exercises in Elderly People
FreeFrail Project: A Multicomponent Intervention for the Management of Frailty in Primary Care: A Randomized Controlled Trial
The primary aim is to assess the effectiveness of a multicomponent intervention including dual-task exercise in improving functionality and cognitive performance and in reducing frailty among community-dwelling adults aged ≥65…
- Conditions
- Frail Elderly, Dual Task Exercises in Elderly People, Exercise Training, Frailty
- Trial name
- NCT07205016
- Testing
- Dual task exercise, Otago exercise
- Volunteers
- 220 people
- Sponsor
- Universitat de Lleida
Frail Elderly People Hospitalized
Evaluation of the Hospital Pathway for Frail Elderly Patients Hospitalised for Pathologies Leading to Medical Decompensation
People aged over 75 account for 25% of emergency department visits in the Provence Alpes Côte d'Azur region. Depending on the facility, around 50% of these patients are discharged home without being hospitalised.
- Trial name
- FRAGIL (NCT06873256)
- Where
- France
- Volunteers
- 310 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Hypertension (HTN)
Stopping Blood Pressure Medications Without Tapering in Long-Term Care
Blood pressure medications may provide limited benefit and cause side effects in frail older adults. It is unclear how best to stop these medications.
- Trial name
- NCT07890129
- Testing
- Deprescribing antihypertensives without a taper
- Where
- 2 sites in Canada
- Volunteers
- 11 people
- Sponsor
- University of Alberta
Fragility
Effects of VIVIFRAIL Program on Functional Capacity and Geriatric Syndromes in the Elderly.
The aim of this quasi-experimental, pretest-posttest study is to evaluate the effectiveness of the Vivifrail multicomponent physical exercise program in improving the functional capacity of pre-frail and frail older adults (aged…
- Trial name
- VIVIAL (NCT07436715)
- Testing
- Behavioral: Vivifrail multicomponent physical exercise program
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Elena Pérez Expósito, MD
Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults
The StayFitLonger Study: an Innovative Computerized Home-based Training to Foster Independent Life at Home
Multimodal training, including physical and cognitive activities, has been associated with a reduction in age-related physical and cognitive decline.
- Conditions
- Cognitive Decline Prevention in Robust Older Adults, Cognitive Decline Prevention in Pre-frail Older Adults, Physical Decline Prevention in Robust Older Adults, Physical Decline Prevention in Pre-frail Older Adults
- Trial name
- SFL (NCT04237519)
- Testing
- SFL training, Active controlled training
- Where
- 4 sites in Belgium, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Pre-frail Elderly
Effects of Combined Motor and Cognitive Training in Pre-frail Elderly
The objective of this study is to investigate psychometric properties of dual-task walking assessments and compare effects of combined motor and cognitive training on physical fitness, brain fitness, and dual-task walking…
- Trial name
- NCT04605809
- Testing
- combined motor and cognitive training, motor training alone, cognitive training alone
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Frailty
Piloting Prehabilitation Before Abdominal Surgery
Frail Veterans are at increased risk for poor surgical outcomes, and as the Veteran population grows older and more frail, there is a critical need to identify effective strategies for reducing surgical risks for these patients.
- Trial name
- NCT03040336
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Dance, Older Adults
Dose-response Effect of Community Dance Programme
The goal of this interventional study is to examine the dose-response effect of Community Dance Programme (CDP) on the physical, cognitive and psychological health of pre-frail and mildly frail community-dwelling older adults.
- Conditions
- Dance, Older Adults, Frailty at Older Adults, Active Ageing
- Trial name
- NCT07081191
- Testing
- Dance, Active Control
- Where
- Singapore
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Pre-frail Senior Adults
What Are the Effects of a Bilateral Hip Exoskeleton During Daily Use by 65+ Adults?
Despite the huge popularity exoskeletons have gained in the past years and the benefits that they have shown to provide to users, there are still many aspects of wearing an exoskeleton that have yet to be determined.
- Trial name
- NCT06041100
- Testing
- Exoskeleton
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Frailty, Frail Elderly
Prehabilitation of Elderly Patients With Frailty Syndrome Before Elective Surgery (PRAEP-GO)
The aim of the study is to evaluate the effect of a shared decision-making conference and three-week prehabilitation program on the outcome "care dependency" one year after surgery.
- Trial name
- NCT04418271
- Testing
- Prehabilitation- new form of care
- Where
- 23 sites in Germany
- Volunteers
- 1,199 people
- Sponsor
- Charite University, Berlin, Germany
Muscle Strengh, Frailty
Effectiveness of Intervention in Prevention of Sarcopenia, Frailty and Functional Decline in Pre-frail Community Elderly
Frailty is a geriatric syndrome characterized by a decrease in the function of various organs and systems that leads to a greater risk of suffering from diseases or disabilities.
- Conditions
- Muscle Strengh, Frailty, Sarcopenia
- Trial name
- ESPAI-F (NCT06280586)
- Testing
- Multidisciplinary intervention
- Where
- 2 sites in Spain
- Volunteers
- 232 people
- Sponsor
- Consorci Sanitari del Maresme
Frail Elderly Syndrome
Home-based Prehabilitation for Elderly Patients
As a consequence of the increasing life expectancy hospitals are seeing a growing number of elderly patients undergoing elective surgery.
- Trial name
- TRAilty (NCT03964363)
- Testing
- Unsupervised home-based physical prehabilitation
- Where
- 3 sites in Germany
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Frail Elderly
Resistance Training to Optimize Health in Pre-frail Older Adults
Exercise programs, particularly resistance training programs using weights or resistance bands, can help improve or maintain mobility and function in older adults, preserve independent living, and improve quality of life.
- Trial name
- NCT02593084
- Testing
- Higher Intensity Resistance Training, Lower Intensity Resistance Training
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- McMaster University
Coronary Artery Disease, Valvular Heart Disease
PRehabilitiation in Elective Frail and Elderly Cardiac Surgery PaTients
Older and more frail adults are more often being referred for cardiac surgery. These patients are often in suboptimal health, and may be physically frail, malnourished, and have other conditions, such as diabetes, that complicate…
- Trial name
- PREFECT (NCT03399162)
- Testing
- PREHAB Workshop, PREHAB Exercise Program
- Where
- Canada
- Sponsor
- Ottawa Heart Institute Research Corporation
Frailty, Pre-Frailty
Frailty Improvement Through Technology With Informal Caregiver Supported Exercise (FITWISE) for Pre-frail and Frail Community-dwelling Older Adults
The goal of this pilot trial is to evaluate the feasibility and potential effectiveness of a caregiver-mediated, technology-facilitated home-based intervention named Frailty Improvement through Technology With Informal Caregiver…
- Trial name
- FITWISE (NCT07519642)
- Testing
- FITWISE, Psychosocial support, Health education control
- Where
- 2 sites in Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Singapore