Clinical trials: Pre- and Postoperative Analgesia
Postoperative Pain
Effect of Oral Melatonin on Postoperative Analgesia After Thoracotomy in Infants
Thoracotomy pain is one of the severest pain that should be taken seriously, especially in children. (1) Inadequate postoperative pain management can compromise respiratory function, delay postoperative extubation, increase the…
- Trial name
- NCT05141344
- Testing
- Melatonin 3 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Ankyloglossia, Oral Mucoceles
The Effect of Pre-emptive Analgesia on the Postoperative Pain in Children Undergoing Pediatric Stomatology Day Surgeries
The aim of this double-blinded, randomized, controlled trial was to test whether pre-emptive analgesia with ibuprofen suppository is effective for children undergoing pediatric stomatology day surgeries in the postoperative…
- Conditions
- Ankyloglossia, Oral Mucoceles, Supernumerary Teeth
- Trial name
- NCT05878262
- Testing
- ibuprofen suppository
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Post Operative Pain
The Use of Ketamine as Rescue Analgesia in the Recovery Room Following Opioid Administration. A Double-blind Randomised Trial in Postoperative Patients
This clinical trial will determine if postoperative patients who have postoperative pain, which has been refractory to morphine administration, will have improved pain relief following a bolus administration of ketamine as…
- Trial name
- NCT00163969
- Testing
- ketamine
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- Bayside Health
Pain
Pre- Versus Post-Incisional Epidural Morphine: Higher Postoperative Pain Perception and Extra Morphine Consumption
Background and Objectives: Neuraxial administration of morphine is an effective way of controlling postoperative pain and reducing analgesic consumption.
- Trial name
- NCT01095575
- Testing
- normal saline 3 ml, morphine 3mg
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain, Supratentorial Brain Tumor
Effects of Pre-emptive Scalp Infiltration With Ketorolac and Ropivacaine for Post-craniotomy Pain
The PAINLESS study is a single-center, prospective, randomized, open-label, blinded-endpoint (PROBE) controlled clinical study to compare the efficacy and safety of pre-emptive scalp infiltration with ropivacaine plus ketorolac…
- Trial name
- NCT04141319
- Testing
- Ketorolac, Ropivacaine, Epinephrine
- Volunteers
- 100 people
- Sponsor
- Beijing Tiantan Hospital
Postoperative Pain
Pre-emptive Dexamethasone in Hip Arthroplasty
Certain studies suggested that preoperative administration of systemic glucocorticoids in patients undergoing hip or knee arthroplasty surgery may improve the postoperative analgesia owing to their anti-inflammatory effect.
- Trial name
- NCT04898920
- Testing
- Normal saline, Dexamethasone
- Where
- Egypt
- Volunteers
- 83 people
- Sponsor
- Tanta University
Knee Replacement, Knee Replacement Surgery
Effect of Virtual Reality on Patient Outcomes and Satisfaction in Total Knee Replacement
This study aims to evaluate the effectiveness of virtual reality (VR) in managing preoperative anxiety and postoperative pain in patients undergoing total knee replacement.
- Conditions
- Knee Replacement, Knee Replacement Surgery, Postoperative Pain, Acute, Anxiety, Preoperative
- Trial name
- NCT06933732
- Testing
- Virtual Reality Intervention for Preoperative Anxiety and Postoperative Pain Management (2 hours), Device: Virtual Reality Intervention for Preoperative Anxiety and Postoperative Pain Management (4 hours), Virtual Reality Intervention for Preoperative Anxiety and Postoperative Pain Management (6 hours)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Aykut Turgut
Postoperative Pain Management
Assessment of Healthcare Professionals' Knowledge and Attitudes Toward Patient-Controlled Analgesia
Patient-controlled analgesia (PCA) is a widely used method for postoperative pain management that allows patients to self-administer analgesics according to their pain needs.
- Trial name
- NCT07359118
- Testing
- Patient-Controlled Analgesia Educational Program
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Pain, Postoperative, Analgesia
Pre-operative Analgesics for Postoperative Pain Relief After Dental Treatment
The aim of the study is to compare the efficacy of the pre-operative administration of Paracetamol and placebo in reducing postoperative pain after routine dental treatment in children.
- Trial name
- NCT02393339
- Testing
- paracetamol
- Where
- Israel
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Osteo Arthritis Knee
Pain Control With Pre-operative Cryoneurolysis Following TKA
The purpose of this study is to assess the potential benefit of preoperative cryoneurolysis in postoperative pain management of total knee arthroplasty patients over current pain management protocol.
- Trial name
- NCT03818022
- Testing
- Cryoneurolysis (Iovera)
- Where
- United States
- Sponsor
- Fondren Orthopedic Group L.L.P.
Post Thoracotomy Pain
The Pre-Emptive Administration Of Ketamine for Controlling Post-thoracotomy Pain
The goal of this paper is to evaluate whether the pre-emptive administration of Ketamine would potentiate the effect of intravenous morphine analgesia in management of post thoracotomy pain.
- Trial name
- NCT03415191
- Testing
- Ketamine, Normal Saline
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University of Campania Luigi Vanvitelli
Post Operative Pain
Pre-incision Versus Lapaorscopic-assisted Transversus Abdominis Plane (TAP) and Rectus Sheath Block for Post-Cholecystectomy Pain
The goal of this clinical trial is to compare pre-incision vs laparoscopic assisted Transversus abdominis plane and rectus sheath block in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT05856682
- Testing
- Laparoscopic-assisted TAP block(LATAP) and Rectus Sheath block
- Where
- Pakistan
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Patel Hospital, Pakistan
Cholecystectomy, Laparoscopic, Pain, Postoperative
Effect of Pre- and Postoperative ESP Block on Frontal QRS-T Angle in Laparoscopic Cholecystectomy
This study aims to investigate the effects of preoperative and postoperative Erector Spinae Plane (ESP) block on the frontal QRS-T angle, a marker of cardiac electrophysiological instability, in patients undergoing laparoscopic…
- Conditions
- Cholecystectomy, Laparoscopic, Pain, Postoperative, Electrocardiography, Regional Anesthesia
- Trial name
- NCT07058194
- Testing
- Preoperative Erector Spinae Plane Block, Postoperative Erector Spinae Plane Block, Standard General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Harran University
Postoperative Anxiety, Pain
The Effect of Operating Room Nurse Visit Prior to Cardiac Surgery on Patients's Anxiety, Pain and Analgesic Use
This study was planned as a quasi-experimental pre-test post-test control group design in non-randomized groups to determine the effect of the preoperative visit by the operating room nurse on the postoperative anxiety level and…
- Conditions
- Postoperative Anxiety, Pain, Postoperative Pain Management
- Trial name
- NCT04525963
- Testing
- Preoperative visit of the operating room nurse and patient education
- Volunteers
- 64 people
- Sponsor
- Nurgül Arpag
Pain, Postoperative, Hepatocellular Carcinoma
Preoperative Pain Control in Liver Surgery Patients
Pregabalin 150mg or placebo are administered 1 hour preoperatively in patients undergoing partial hepatectomy. Postoperatively, patients receive morphine as rescue analgesic.
- Trial name
- NCT01923948
- Testing
- Pregabalin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Head and Neck Cancer, Pain, Postoperative
Pre-Operative Pregabalin for Post-Operative Pain in Head and Neck Cancer Surgery
The purpose of this study is to evaluate and reduce pain and improve quality of life in patients being treated for head and neck cancer with primary tumor resection and bilateral neck dissections.
- Trial name
- NCT03714867
- Testing
- Pregabalin 150mg
- Where
- United States
- Sponsor
- Augusta University
Pain Management, Arthroplasty
Effect of Preoperative Pain Education on Anxiety, Pain, and Analgesic Use in Total Knee and Hip Replacement Patients
This randomized controlled trial evaluates whether a standardized preoperative pain education session delivered by a nurse reduces postoperative pain intensity and surgical anxiety among adult elective orthopedic surgery patients…
- Conditions
- Pain Management, Arthroplasty, Knee Replacement, Hip Replacement
- Trial name
- Pain-Anxiety (NCT07362589)
- Testing
- Pain education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Yeditepe University
Phantom Limb Pain
Optimized Perioperative Analgesia Reduces the Prevalence and the Intensity of Phantom Pain in Lower Limb Amputation
Severe pre-amputation pain is associated with phantom pain development, and phantom pain models assign major importance to central and peripheral nervous system changes related to pre-amputation pain.
- Trial name
- NCT00443404
- Testing
- perioperative epidural catheter
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Patras
Pain, Analgesia
Post-Operative Pain Scores and Analgesic Requirements After Elective Inguinal Herniorrhaphy
The study will investigate the effects of single dose pre-operative oral dose of gabapentin (1200) on post -operative pain scores and oral analgesic requirements.
- Conditions
- Pain, Analgesia, Hernia, Inguinal
- Trial name
- NCT00735124
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Oklahoma
Conscious Sedation, Postoperative Analgesia
Analgo-Sedative Effects Of Oral, Or Nebulized Ketamine In Pre-schoolers Undergoing Elective Surgery.
the primary objective of this study is to investigate the sedative, and analgesic effects of oral, or nebulized ketamine as premedication drugs, and providing postoperative analgesia for the preschoolers and decrease their need…
- Trial name
- NCT03885427
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Zagazig University