Clinical trials: Pre-Diabetic
Obesity, Obesity, Abdominal
Vestibular Stimulation to Trigger Adipose Loss Clinical Trial
There is an ongoing and worsening problem with obesity in the developed, and much of the developing world. Although it has long been realized that Western diets that are rich in sugar and fat play an important role in this, it…
- Conditions
- Obesity, Obesity, Abdominal, Metabolic Syndrome, Weight Loss
- Trial name
- VeSTAL (NCT03138369)
- Testing
- Vestibular nerve stimulator
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Neurovalens Ltd.
Healthy, Prediabetes
Effect of Visualization of Functional Milk Efficacy on Perceived Benefits
This study aims to demonstrate the effect of visualizing the effect of consuming a functional milk on postprandial glucose response on perceived benefits compared to absence of visualization.
- Conditions
- Healthy, Prediabetes, Asian, Adult
- Trial name
- NCT06864364
- Testing
- CGM feedback visualization, milk supplemented with mulberry leaves extract, blinded CGM feedback visualization
- Where
- China
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Obesity
Weight Loss in Pre-diabetic, Obese Women
This is a six (6) month, single center, randomized, double-blind, parallel, controlled-feeding weight-loss study comparing two dietary groups (triglyceride and olestra) in pre-diabetic obese women.
- Trial name
- NCT00686816
- Testing
- Low calorie diet, Olestra
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Procter and Gamble
Diabetes Mellitus, Type 2, Pre-diabetes
Prediabetes and Type 2 Diabetes Data Collection Study
To collect data in an observational study from Prediabetes (PD) and Type 2 Diabetes (T2D) patients including time correlated CGM, medication and food intake approximately 80% of the time for each subject that completes the entire…
- Trial name
- T2Help (NCT04503239)
- Testing
- G6
- Where
- 5 sites in United States
- Volunteers
- 306 people
- Sponsor
- DexCom, Inc.
Childhood Obesity, Prediabetes
Clinical Utility of SUDOSCAN in the Pediatric Population
The main purpose of this study is to evaluate whether SUDOSCAN is a valid, accurate clinical device for the the determination of sweat gland function in the pediatric population.
- Conditions
- Childhood Obesity, Prediabetes, Diabetes
- Trial name
- NCT02216201
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Impeto Medical
Diabetes, Diabetes Mellitus, Type 2
A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic Drugs
This trial is conducted in Asia. The aim of this trial is to compare the efficacy and safety of insulin degludec/liraglutide and insulin degludec both in combination with metformin in Japanese subjects with type 2 diabetes…
- Trial name
- DUAL™ II Japan (NCT02911948)
- Testing
- Insulin degludec/liraglutide, Insulin degludec
- Where
- 38 sites in Japan
- Volunteers
- 210 people
- Sponsor
- Novo Nordisk A/S
Diabetes, Pre-diabetes
Glucose Risk Assessment in Employer Populations
This is an observational study to understand the glucose characteristics of the general population (normal glucose, pre-diabetes, and diabetes).
- Conditions
- Diabetes, Pre-diabetes, Glucose Intolerance
- Trial name
- NCT04529824
- Testing
- Dexcom G6 Continuous Glucose Monitor (CGM) System
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- DexCom, Inc.
Pre Diabetes, Overweight
A Study to Determine the Safety and Tolerability of a Range of Doses of PeptiControl in Pre-diabetic Individuals
A randomised, double blind, placebo controlled parallel study to examine the effects of a dose range of PeptiControl, a plant-based ingredient, in pre-diabetic males and females.
- Trial name
- NCT06440213
- Testing
- PeptiControl™ (Low - Dose 435 mg/day), PeptiControl™ (Mid - Dose 870 mg/day), PeptiControl™ (High - Dose 2610 mg/day)
- Where
- 4 sites in India
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Nuritas Ltd
Glycemic Response
Study of a Carbohydrate Drink in Adults
The objective of this study is to determine the postprandial glycemic response and rates of gastric emptying in healthy subjects and those with pre-diabetes and type 2 diabetes following oral ingestion of carbohydrate.
- Trial name
- NCT04313920
- Testing
- Nutritional Supplement
- Where
- 3 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Diabetes Mellitus, Type 2
A Research Study to Compare Two Types of Insulin, a New Insulin, Insulin Icodec and an Available Insulin, Insulin Glargine, in People With Type 2 Diabetes Who Have Not Used Insulin Before
This study compares insulin icodec (a new insulin taken once a week) to insulin glargine (an insulin taken once daily which is already available on the market) in people with type 2 diabetes.
- Trial name
- ONWARDS 1 (NCT04460885)
- Testing
- Insulin icodec, Insulin glargine
- Where
- 198 sites in United States, Croatia and 11 more
- Volunteers
- 984 people
- Sponsor
- Novo Nordisk A/S
PreDiabetes
To Evaluate the Impact of Consumption of a Bioactive Compound on Fasting Blood Glucose Levels in Asian Indians With Pre-diabetes
This is randomized placebo controlled, double-blinded, parallel arm study on free living Asian Indians. Eligible subjects will undergo one-week run-in period and subjects will be asked to maintain their usual diet and exercise…
- Trial name
- NCT06417840
- Testing
- N-trans-caffeoyltyramine (NCT) and N-trans-feruloyltyramine (NFT)
- Where
- India
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Brightseed
Diabetes Mellitus, Gestational Diabetes Mellitus (GDM)
A Proof of Concept (PoC), Randomized, Controlled Study to Validate the Algorithm and Evaluate the Accuracy, Safety and Pain Level of the Smartest-AE in Comparison to Self-measure Blood Glucose Levels
The study is conducted in Israel so plain language for the study is exist in Hebrew only
- Conditions
- Diabetes Mellitus, Gestational Diabetes Mellitus (GDM), Pre Diabetes
- Trial name
- NCT06587087
- Testing
- Smartest-AE: The lancet that will be used will be the Vitrex Soft Lite lll 28G.
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Smartest Technologies
Age-Related Macular Degeneration, Branch Retinal Vein Occlusion with Macular Edema
Ocular Safety and Usability Study for FYB203 PFS
The objective of the study is to assess the ocular safety of the FYB203 pre-filled syringe in terms of preparation and administration by Retina Specialists in the clinical setting.
- Conditions
- Age-Related Macular Degeneration, Branch Retinal Vein Occlusion with Macular Edema, Central Retinal Vein Occlusion with Macular Edema, Diabetic Macular Edema
- Trial name
- NCT06708637
- Testing
- FYB203 2 mg (0.05 mL of 40 mg/mL)
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- Formycon AG
Prediabetes
Effects of Yoghurt Consumption on Glucose Metabolism in Prediabetic Subjects
The purpose of this study is to explore the effects of yoghurt consumption on glucose metabolism in prediabetic subjects.
- Trial name
- SNOWFALL (NCT06836752)
- Testing
- Yoghurt, Milk
- Where
- France
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Pre-diabetes
7-Ketolithocholic Acid in Prediabetes
7-Ketolithocholic Acid, a naturally occurring bile acid, is a novel food currently under investigation for potential metabolic benefits, including glucose-lowering effects.
- Trial name
- NCT07650123
- Testing
- 7-KLCA, Diet and Physical Activity
- Where
- 8 sites in Italy
- Volunteers
- 100 people
- Sponsor
- ICE S.p.A.
Diabetes Mellitus
Intraoperative Dexamethasone and Its Effect on Hyperglycemia
To study the effect of intra-operative dexamethasone on the management of post-operative blood sugar in diabetic patients.
- Trial name
- NCT03646916
- Testing
- Dexamethasone, No dexamethasone
- Where
- United States
- Sponsor
- Ascension Health
Weight Loss, Metabolic Syndrome
Use of Continuous Glucose Monitoring in Non-Diabetic Population to Compliment Signos Mobile Health Platform
Metabolic syndrome and resulting downstream health effects remains a growing health concern. In published trials, the use of continuous glucose monitoring (CGM) assists behavioral changes efforts, leading to improved adherence…
- Conditions
- Weight Loss, Metabolic Syndrome, Pre-diabetes, Central Obesity
- Trial name
- NCT05121844
- Testing
- Continuous Glucose Monitor Device
- Where
- United States
- Volunteers
- 31,187 people, healthy volunteers welcome
- Sponsor
- Signos Inc
Prediabetes
Effect of Inulin-type Fructose Extracted From Jerusalem Artichoke on Improving Prediabetic State of Type 2 Diabetes
The trial was a multicenter, randomized, double-blind, placebo-controlled, parallel-controlled, exploratory clinical study.Through the intervention of soluble dietary fiber in the pre-type 2 diabetic population, the change of…
- Trial name
- NCT03794232
- Testing
- NIUCHANG
- Volunteers
- 246 people
- Sponsor
- Inuling (Bei Jing) Science and Technology Co. Ltd
Obesity
Research Study Looking at How Well Semaglutide Works in People Living With Obesity and Prediabetes
This study looks at how well a new medicine, called semaglutide, works at helping people with obesity and prediabetes. This study will look at how much weight participants lose, and if participants can go from having blood sugar…
- Trial name
- STEP 10 (NCT05040971)
- Testing
- Semaglutide 2.4 mg
- Where
- 43 sites in Canada, Denmark and 3 more
- Volunteers
- 207 people
- Sponsor
- Novo Nordisk A/S
Overweight and Obesity
The Effect of Extended Use of the EPITOMEE CAPSULE (ELECT)
The Effect of Extended Use of the Epitomee Capsule on BodyWeight in subjects with Overweight and Obesity with and without Prediabetes
- Trial name
- NCT04994769
- Testing
- Epitomee Capsule
- Where
- 3 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Epitomee medical