Clinical trials: Pre-Diabetic
Prediabetic State, Overweight
OXXYNEA® GS: Study for Glycaemia Management
The aim of this study is to develop a proof of concept establishing a causal relationship between glycemia improvement through combination of polyphenols-rich botanical extracts or polyphenols-rich botanical extracts associated…
- Trial name
- NCT05926947
- Testing
- Verum A, Verum B
- Where
- Spain
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Fytexia
Prediabetes
Effect of Resistant Starch on Insulin Sensitivity and Beta Cell Function in Subjects With Prediabetes
To compare the use supplementation based on green banana flour versus placebo in the insulin sensitivity on individuals who have prediabetes.
- Trial name
- NCT03294915
- Testing
- Resistant Starch
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pre Diabetic
PASO A PASO: Tailored Diabetes Prevention Program for Spanish-Speaking Communities Feasibility Study
The interdisciplinary and interprofessional community-academic partnership (CAP) has been working with Spanish-speaking H/L Salt Lake City residents and organization leaders to adapt the National Diabetes Prevention Program to…
- Trial name
- NCT07392008
- Testing
- Paso a Paso
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Utah
Prediabetic State
RCT of a Polyherbal Dietary Supplement for Prediabetes
The primary purpose of this study is to evaluate the impact of a polyherbal dietary supplement (Designs for Health - GlucoSupreme™ Herbal) on markers of glycemic control and other structure/function outcomes among a sample of…
- Trial name
- NCT03388762
- Testing
- GlucoSupreme™ Herbal
- Where
- 4 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Branched-chain Amino Acid Metabolism, Insulin Sensitivity
Regulation of Branched-chain Amino Acid Metabolism in Pre-Diabetes
Elevated circulating levels of certain amino acids (the building blocks of protein) are strongly associated with insulin resistance.
- Trial name
- BCAAM-PD (NCT01786941)
- Testing
- Pre-Diabetes Group - 6-mo Aerobic and Resistance combined exercise training, GBP Group - Non-diabetics intending to undergo Gastric Bypass surgery
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Duke University
Prediabetic State
Clinical Study to Assess the Long-term Effect of Pep2Dia® on Glucose Homeostasis in Prediabetic Subjects
The goal is to assess the long-term effect of Pep2Dia® compared to placebo intake on blood glucose homeostasis. Respective improvements will be assessed by changes in glycated haemoglobin (HbA1c) before and after the 12-weeks…
- Trial name
- NCT05391854
- Testing
- Pep2dia
- Where
- Germany
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ingredia S.A.
Diabetes Mellitus, Chronic Disease
Meta-analyses of Liquid Versus Solid Calories and Body Weight
Consumption of sugar-sweetened beverages (SSBs) has been linked to rising rates of overweight and obesity. The most prominent mechanism to explain the link between SSBs and obesity is that liquid calories are not perceived by the…
- Conditions
- Diabetes Mellitus, Chronic Disease, Cardiovascular Diseases, Prediabetic State
- Trial name
- NCT02702440
- Testing
- Liquid calories from sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
PreDiabetes, Nutrition
Zinc, Chromium, Vitamin C, and Copper Combination Supplement for Prediabetes Progression
Currently, the incidence of diabetes mellitus is increasing worldwide. People with prediabetes have higher risk to develop diabetes mellitus type 2.
- Trial name
- CHANGE (NCT04511468)
- Testing
- Zinc, Chromium, Vitamin C, and Copper Supplementation, Standard healthy lifestyle intervention
- Where
- Indonesia
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Diabetes Mellitus, Type 2, PreDiabetes
Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance
This 12-week controlled diet and weight intervention study seeks to define the molecular pathways that link excess body weight to the development of insulin resistance (IR).
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Insulin Resistance, Obesity
- Trial name
- NCT05165706
- Testing
- Dietary Intervention Mediterranean Low Carbohydrate Diet, Dietary Intervention Standard Low Carbohydrate Diet, Dietary Intervention Standard Low Fat Diet
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Stanford University
Dietary Habits
Study to Investigate the Effect of Dietary Fibre Supplementation on Long-term Glucose Control in Prediabetic Subjects
The purpose of the study is to explore the potential metabolic health benefits of a dietary fibre intervention by using Soluble Fibre in a human intervention study in Healthy Obese Pre-diabetic participants over a period of 16…
- Trial name
- NCT05157815
- Testing
- Soluble Fibre, Calorie Matched Control
- Where
- Ireland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Tate & Lyle
Pre-biabetes
Effects of Milk Probiotics Intervention on Blood Glucose Control Middle-aged and Elderly People With Pre-diabetes
This study aims to conduct a 8-week probiotics intervention involving for middle-aged and elderly individuals with pre-diabetes, assessing its impact on blood glucose control in comparison to placebo
- Trial name
- NCT06972524
- Testing
- a special probiotics from Mengniu Group, supplemented with milk powder, regular milk powder does not contain any additional supplementation, and the color, flavor, shape, taste, and weight are same with the probiotic milk powder
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Huilian Zhu
Diabetic Retinopathy
Augmenting Referral Pathway to Improve Uptake of Retinal Services by Diabetic Patients
Reiyukai Eiko Masunaga Eye Hospital (REMEH) is a non-profitable organization. Retina services were resumed from October 2019. Until this retinal service started, it has been mostly cataract-focused.
- Trial name
- NCT04829084
- Testing
- Pre-post educational intervention
- Where
- Nepal
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Seva Foundation
Osteoporosis, Metabolic Syndrome
Body Composition and Risk for Development of Pre-diabetes in Post-menopausal Chinese Women in Singapore
This project aims to ascertain that novel imaging and metabolic markers can be used to identify as well as to validate and improve the detection of Singapore-Chinese women at increased risk of diabetes.
- Trial name
- NCT03503552
- Where
- Singapore
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- JeyaKumar Henry
Type 2 Diabetes Mellitus (T2DM), Cognitive Function
Prediabetes and Type 2 Diabetes in Aging
This case-control study will evaluate the effects of geriatric individuals on cognitive status, physical function and fatigue. Our study aims to compare the effects of geriatric individuals with prediabetes and type 2 diabetes…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Cognitive Function, Dual Task, Fatigue
- Trial name
- NCT06953609
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Uşak University
PreDiabetes, Appetitive Behavior
Prediabetes, Exercise, and Appetite Regulation
The purpose of the study is to learn about how type of exercise influences measures of appetite regulation.
- Trial name
- PEAR (NCT04910763)
- Testing
- Resistance Exercise
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Utah
Prediabetes
The Association Between Body Constitution and Meridian Energy in Prediabetes
Traditional Chinese medicine (TCM) theories assert that body constitution and meridian energy are the foundations for disease prevention. However, few studies have incorporated TCM concepts into risk factors.
- Trial name
- NCT05475587
- Testing
- Routine care
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
PreDiabetes, Impaired Fasting Glucose (IFG)
Metformin and Its Impact on the Substances Associated With NO Production in Prediabetes Patients.
This study evaluates the effect of different doses of metformin on the function of endothelium in people with pre-diabetes. One group of the patients will receive metformin in dose: 1500 mg, the second one will receive 3000…
- Conditions
- PreDiabetes, Impaired Fasting Glucose (IFG), Impaired Glucose Tolerance (IGT)
- Trial name
- NCT03398356
- Testing
- Metformin
- Where
- Poland
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
PreDiabetes
A Trial to Assess Diets Containing Beef vs. Poultry on Pancreatic Beta-Cell Function
The objective of this study is to assess and compare the effects of usual diets containing lean beef vs. lean poultry on pancreatic beta-cell responses in men and women with prediabetes.
- Trial name
- NCT05456477
- Testing
- Beef, Poultry
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
PreDiabetes, Type 2 Diabetes
Type 2 Diabetes Prevention in Community Health Care Settings for at Risk Children and Mothers
The two main questions that this research study will answer: 1. will a 16-week community-based diabetes prevention program for delivery to at-risk mothers and children in a Federally Qualified Health Center (FQHC) setting show…
- Trial name
- NCT03781102
- Testing
- 16-Week Diabetes Prevention Program for Mothers and Children
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Pre Diabetes
Personalized Nutrition for Pre-Diabetes
The Personalized Nutrition Project for Prediabetes (PNP3) study will investigate whether personalized diet intervention will improve postprandial blood glucose levels and other metabolic health factors in individuals with…
- Trial name
- NCT03222791
- Testing
- Algorithm-based diet, Mediterranean-style low-fat diet
- Where
- Israel
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Weizmann Institute of Science