Clinical trials: Pre-Term
Pain
Analgesic Effect of Oral 25% Glucose Versus Oral 24% Sucrose for Pain Relief During Heel Lance in Preterm Neonates
RESEARCH HYPOTHESIS-In preterm neonates during heel lance oral 25% glucose is more efficacious in reducing pain as compared to oral 24% sucrose when assessed by PIPP(Premature infant pain profile)
- Trial name
- NCT01931020
- Testing
- Sucrose, Glucose
- Where
- India
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Lady Hardinge Medical College
Preterm Labor, Cervical Incompetence
Cervical Cerclage for Singleton Pregnant on Vaginal Progesterone With Progressive Cervical Length Shortening
The aim of this study is to Determine whether cerclage with vaginal progesterone will: 1. Reduce the overall spontaneous preterm birth rate. 2. Prolong pregnancy latency. 3. Improve neonatal outcome.
- Trial name
- NCT03837288
- Testing
- Cerclage
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Preterm
The Effect of Parental Participation on Newborn Comfort During Diaper Care
It was aimed to determine the effect of parental participation on newborn comfort during diaper care practice in preterm infants.
- Trial name
- NCT06345742
- Testing
- No parental participation, Mother participation, Father participation
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Preterm Infant, Infant, Newborn
Neonatal Wireless Monitoring System for Intensive Care
Babies who require intensive care need to have their heart rate, oxygen levels and temperature measured continuously using specially designed monitors.
- Conditions
- Preterm Infant, Infant, Newborn, Low; Birthweight, Extremely (999 Grams or Less)
- Trial name
- NCT04241263
- Testing
- Wireless vital sign monitoring - comparative, Wireless vital sign monitoring - usability
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Premature Birth, Cerebral Palsy
Neuro-biomechanical Determinants for Motor Behavior in High-risk Infants
This project focuses on motor development, muscle growth and muscle activity. Using advanced, instrumented tests such as , the link between muscles and the movement characteristics will be studied.
- Conditions
- Premature Birth, Cerebral Palsy, Neurodevelopmental Disorders, Brain Injuries
- Trial name
- BAMBI (NCT06111898)
- Testing
- No Intervention
- Where
- Switzerland
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Preterm Labor, Respiratory Distress Syndrome
The Relationship of Fetal Lung Elastography Values With the Development of Respiratory Distress in Cases of Preterm Labor
The aim of this study was to compare fetal lung elastography (FAE) values between groups with and without Respiratory Distress Syndrome (RDS) in preterm neonates and to evaluate the potential of FAE to predict the risk of…
- Trial name
- NCT06168149
- Testing
- fetal lung elastography measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Preterm Birth
Physical Exam Indicated Cerclage in Singleton Gestation 24 Weeks to 25 Weeks and 6 Days Gestation
RCT assessing preterm delivery rate in singleton pregnancies having a physical-exam indicated cerclage placed between 24 weeks and 25 weeks and 6 days.
- Trial name
- NCT05501938
- Testing
- Physical Exam Indicated Cerclage
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Ventricular Premature Complexes
CBT for Premature Ventricular Contractions
The purpose of the present interdisciplinary research program is to develop and evaluate a disease-specific cognitive behavior therapy (CBT) protocol to increase quality of life (QoL) and reduce symptom burden in patients with…
- Trial name
- PVC-CBT (NCT05087238)
- Testing
- CBT
- Where
- Sweden
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Preeclampsia, Preterm Birth
Prediction of Preeclampsia and Other Pregnancy Complications Following Combined Iterative Screening
Preterm birth (PTB), preeclampsia (PE), fetal growth restriction (FGR) and intra-uterine fetal death (IUFD) constitutes the main causes of perinatal morbidity and mortality and are called "Great Obstetrical Syndromes".
- Conditions
- Preeclampsia, Preterm Birth, Fetal Growth Restriction, Intra Uterine Fetal Death
- Trial name
- PREDICTION2 (NCT03067298)
- Where
- Canada
- Volunteers
- 805 people, healthy volunteers welcome
- Sponsor
- Emmanuel Bujold
Vitamin D, Vitamin B12 and Folic Acid Among Patients With Premature Ejaculation
Assessment of Serum Levels of Vitamin D, Vitamin B12 and Folic Acid Among Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Treatment.
Therefore, this study will aim to assess serum levels of vitamin D, vitamin B12 and folic acid among patients with lifelong PE and non-responding to dapoxetine treatment.
- Trial name
- PE (NCT04355949)
- Testing
- Serum vitamin D, vitamin B12, folic acid
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Preterm Labor, Cerebral Palsy
Calcium Channel Blockers Compared to Magnesium Sulfate in Fetal Cerebral Blood Flow
The aim of this study is to investigate the possible use of calcium channel as a neuroprotectant in cases with PTL. This will be done by comparing the effect they have on cerebral blood vessels with the already established MgSo4.
- Trial name
- NCT02591004
- Testing
- Magesium sulphate, Nifedipine, Doppler on fetal middle cerebral artery
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Prematurity
Accuracy of 5D LB Ultrasound in Predicting Birth Weight of Preterm Fetuses : A Pilot Study
5D and 2D ultrasound will be done for pregnant women within 72hours before preterm delivery to determine estimated fetal weight by ultrasound.
- Trial name
- NCT02401438
- Testing
- 5D ultrasound, 2D ultrasound
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Habituation, Psychophysiological, Preterm, Infant
Habituation's Mechanisms in Preterm and Term Infants
Each year in France, 7 % of newborns are born preterm (before 37 weeks of gestational age (GA)). The investigators called very preterm infants those who were born before 33 weeks of GA.
- Trial name
- HABIPREMA (NCT02496104)
- Testing
- Package n°1 of the APIB
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Pregnancy
Tobacco Use in Pregnancy Intervention for Cessation
The proposed project will test the effectiveness of the novel delivery of an established tobacco cessation treatment among pregnant women in Kentucky.
- Trial name
- ToPIC (NCT03442530)
- Testing
- ToPIC, Tobacco Treatment As Usual (TTAU)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kristin Ashford
Atrial Fibrillation, Atrial Flutter
Excessive Supraventricular Activity and Atrial Fibrillation
The aim of the proposed study is to determine if individuals with excessive supraventricular ectopic activity (ESVEA) on Holter recording should be subjected to prolonged screening with Event loop recorder in order to detect…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Supraventricular Beat, Premature, Premature Supraventricular Beats
- Trial name
- ESA-AF (NCT04593498)
- Testing
- Holter recording, Echocardiography (Echo), Blood sample
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Infections, Streptococcal
Study to Evaluate the Safety and Immunogenicity of a 10-valent Pneumococcal Conjugate Vaccine in Preterm Infants
This study aims to evaluate the safety, reactogenicity and immunogenicity of GlaxoSmithKline (GSK) Biologicals´ 10-valent pneumococcal conjugate vaccine when co-administered with diphtheria, tetanus, acellular pertussis-hepatitis…
- Trial name
- NCT00390910
- Testing
- Pneumococcal conjugate vaccine GSK1024850A, Infanrix hexa
- Where
- 8 sites in Greece, Spain
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV-1-infection, Aging, Premature
Mental Ability Challenge Study in Adults With and Without HIV
It is estimated that by 2016, nearly 50% of HIV-positive individuals in the US will be aged 50 or older, and up to 60% of those will experience some degree of cognitive impairment as they age.
- Conditions
- HIV-1-infection, Aging, Premature, Cognitive Impairment, Memory Impairment
- Trial name
- NCT03244488
- Testing
- Scopolamine Injectable Product, Mecamylamine Pill
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Preterm Labor
Uterine Artery Doppler Indices and Uterocervical Angle Measurment in Prediction of Preterm Labor
The goal of this observational study is to evaluate the role of uterine artery doppler indices and uterocervical angle measurement in prediction of preterm labor .The main question it aims to answer is: Does combination of both…
- Trial name
- NCT07336173
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Bronchopulmonary Dysplasia
Preliminary Study on Microplastics Deposition in Ventilator Circuit and the Risk of Bronchopulmonary Dysplasia in Premature Infants
In this study, the premature infants with gestational age less than 30 weeks were taken as the object, and the deposition characteristics of microplastics in ventilator circuit and its correlation with the risk of…
- Trial name
- Microplastics (NCT07848646)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Huiyi Li
Preterm Birth
Molecular Signature Children
Preterm birth (PTB) occurs before 37 weeks of gestation and is a major cause of neonatal mortality and morbidity. PTB results from heterogeneous influences.
- Trial name
- MSP_Ext (NCT03104673)
- Where
- Thailand
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University of Oxford
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