Clinical trials: Pre-frail Elderly
Frail Elderly Syndrome, Bladder Disease
Perioperative Multimodal Care for Cystectomy Frail Patient
Major surgery in the elderly and frail patient is a challenge. Optimal perioperative management is essential for outcome and survival.
- Conditions
- Frail Elderly Syndrome, Bladder Disease, Nutrition Disorders, Cognitive Symptom
- Trial name
- NCT03065348
- Testing
- oral whey protein, Immunonutrition, Carbohydrate Drink
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Frail Elderly Syndrome
Effectiveness of a Socio-Community Health Intervention on Pre-Frailty in Older Adults
The objective of this study is: To evaluate the effectiveness of a health intervention with a socio-community approach on frailty in older adults with pre-frailty.
- Trial name
- NCT06663150
- Testing
- health intervention with a socio-community approach
- Where
- Colombia
- Volunteers
- 160 people
- Sponsor
- Keralty SAS. Colombia
Frailty, Frailty Syndrome
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Frailty syndrome (i.e. frailty) is a geriatric syndrome which relies on the reduction of multisystem reserve capacity. Frail people have a lower potential to respond to external stressors and various life incidents as well as…
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility
- Trial name
- FRAILPOL (NCT04518423)
- Where
- Poland
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Frail Elderly Syndrome, Sarcopenia
Multidimensional Intervention in Pre-frail Patients Older Than 70 Years
Aging represents a huge advance in society and a health and social challenge. Spain has one of the highest life expectancies in the world, but other countries with the same demographic characteristics are ahead of us in quality…
- Trial name
- NCT04574271
- Testing
- Intensive dietary advice and exercise prescription, Usual dietary advice and exercise prescription
- Where
- Spain
- Volunteers
- 340 people
- Sponsor
- Endocrinology and Clinical Nutrition Research Center, Spain
Frailty, Sleep Quality
Acupoint Stimulation and Exercise for Taiwanese Pre-frail Older Adults
This study aims to explore the relationships between frailty, daily physical activity, sleep quality, and Traditional Chinese Medicine (TCM) constitutions among older adults in Taiwan.
- Conditions
- Frailty, Sleep Quality, Aging
- Trial name
- NCT07732530
- Testing
- Vivifrail Exercise Program, Acupoint Stimulation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Tainan Hospital, Ministry of Health and Welfare
Pre-frail
Effects of Whole Body Vibration in Pre-frail Individuals Over 65 Years of Age
In this study, individuals aged 65 and over who applied to the physical medicine and rehabilitation outpatient clinic with any complaint will be evaluated in terms of geriatric syndromes.
- Trial name
- NCT06004999
- Testing
- Whole body vibration, The exercise program on flat ground without a vibration platform
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Trakya University
Hypertension (HTN)
Stopping Blood Pressure Medications Without Tapering in Long-Term Care
Blood pressure medications may provide limited benefit and cause side effects in frail older adults. It is unclear how best to stop these medications.
- Trial name
- NCT07890129
- Testing
- Deprescribing antihypertensives without a taper
- Where
- 2 sites in Canada
- Volunteers
- 11 people
- Sponsor
- University of Alberta
Community-dwelling Seniors, History of a Fall in the Previous 12 Months
Zurich Disability Prevention Trial
This project was designed to optimizing vitamin D status in prefrail seniors age 70+ living at home and prevent their functional decline. We test 3 arms of monthly vitamin D supplementation.
- Trial name
- ZDPT (NCT01017354)
- Testing
- Hidroferol® (ES), ViDe3 (CH)
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Zurich
Frailty, Pre-operative Exercise
Home-based Exercise for Frail Individuals Prior to Cardiac Surgery
The goal of this quasi-experimental feasibility study is to determine if a home based exercise program, that is supported virtually by a physiotherapist, is feasible for frail adults that are waiting for cardiac surgery.
- Conditions
- Frailty, Pre-operative Exercise, Prehabilitation, Cardiac Surgery
- Trial name
- NCT05834556
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Dr. Todd A Duhamel
Pre-frail Elderly
The Effect of Cholecalciferol in Pre-frail Elderly
Vitamin D plays important role in musculoskeletal health and has been known to influence immune system. Inflammaging is one of risk factors that may contribute to development of frailty in elderly.
- Trial name
- NCT04847947
- Testing
- Cholecalciferol
- Where
- Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Frailty, Ventral Hernia
Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia Repair
The purpose of this study is to assess the physical fitness of patients undergoing hernia repair and correlate the postoperative outcomes and recovery as well as assess the impact of a targeted physical exercise program…
- Trial name
- NCT06874413
- Testing
- Prehabilitation, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Prisma Health-Upstate
Frail Elderly Syndrome, Frailty
Seated Physical Activity in Ageing
This trial will take the form of a feasibility study; designed to assess the feasibility of a proposed future clinical trial in this setting.
- Conditions
- Frail Elderly Syndrome, Frailty, Physical Activity
- Trial name
- SPAA (NCT03141866)
- Testing
- Exercise Intervention 1: Move It Or Lose It (MIOLI), Exercise Intervention 2: Machine-based resistance training intervention
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Birmingham
Health Services for the Aged
Multicomponent Exercise on Executive Function and Balance
The present study is to examine the effects of a multicomponent exercise on executive function and balance in pre-frail older adults.
- Trial name
- NCT03611192
- Testing
- Multicomponent exercise, Home-program exercise
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Yang Ming Chiao Tung University
Frailty
Piloting Prehabilitation Before Abdominal Surgery
Frail Veterans are at increased risk for poor surgical outcomes, and as the Veteran population grows older and more frail, there is a critical need to identify effective strategies for reducing surgical risks for these patients.
- Trial name
- NCT03040336
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Frailty, Muscle Weakness
The Effects of Functional Power Training on Frail and Pre-frail Community - Dwelling Older Adults in Singapore
To investigate the efficacy of a 12-week Functional Power Training (FPT) program in pre-frail and frail community-dwelling older adults in Singapore for the management of physical frailty.
- Trial name
- NCT04438876
- Testing
- Functional Power Training, Usual care
- Where
- Singapore
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Geriatric Education and Research Institute
Aging, Frailty
Mitophagy and Autophagy in Elderly Subjects
In recent years, evidence has shown that mitochondrial dysfunction plays an important role in the development of age-related muscle decline that may lead to frailty.
- Conditions
- Aging, Frailty, Mitophagy
- Trial name
- NCT02472340
- Testing
- Muscle Biopsy
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Frailty Syndrome, Prefrail Elderly
Comparıson of the Effıcacy of Conventıonal Exercıse and Pılates ın Pre-fraıl and Fraıl Older Adults
Brief Summary This clinical study aims to compare the effects of a conventional exercise program and a Pilates exercise program in prefrail and frail older adults.
- Conditions
- Frailty Syndrome, Prefrail Elderly, Frail Elderly, Geriatric
- Trial name
- NCT07458048
- Testing
- PILATES EXERCISES GROUP, CONVENTIONAL EXERCISES GROUP
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Physical Frailty
Protein and Exercise to Counteract Frailty in Older Adults
The purpose of this study is to determine the effects of interventions with high-protein diet alone or in combination with resistance training on muscle mechanical function (muscle power and strength), frailty status, functional…
- Trial name
- NCT03842579
- Testing
- Resistance training, High-protein diet, Recommendations
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark
Colon Cancer, Fragility
Prehabilitation in Frail Colon Cancer
Objectives To investigate the impact of tele-supervised prehabilitation on functional capacity in frail colon cancer patients undergoing colorectal resection and to evaluate the effects of prehabilitation on muscle strength and…
- Trial name
- NCT03097224
- Testing
- Prehabilitation
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Frail Older Adult Syndrome, Nutrition Poor
PROTein to Enhance outComes of (Pre)Frail paTients Undergoing Cardiac Surgery
Heart disease in an aging population has resulted in heart surgery being offered to older and more frail patients. Frail patients which make up more than 50% of patients currently undergoing heart surgery are vulnerable to having…
- Conditions
- Frail Older Adult Syndrome, Nutrition Poor, Cardiovascular Morbidity
- Trial name
- PROTECT-CS (NCT04038294)
- Testing
- ISOlution protein supplement
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- St. Boniface Hospital