Clinical trials: Pre-hypertension
Breastfeeding, Breastfeeding Initiation
Birth & Breastfeeding Support Study
The goal of this observational study is to learn about the effects of birth practices such as cesarean section and vacuum assisted birth and diseases such as gestational diabetes and preeclampsia on exclusive breastfeeding.
- Conditions
- Breastfeeding, Breastfeeding Initiation, Breastfeeding Duration, Birth
- Trial name
- BABSS (NCT06844019)
- Where
- Denmark
- Volunteers
- 1,628 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Pregnancy Toxemia, Hypertension
Treatment Targets for Chronic Hypertension in Pregnancy
This project is a clinical study of women with high blood pressure who become pregnant. Preeclampsia is a syndrome developing at the end of a pregnancy characterized by an abrupt rise in blood pressure (BP), blood clotting and…
- Conditions
- Pregnancy Toxemia, Hypertension, Proteinuria
- Trial name
- NCT00194974
- Testing
- methyldopa, labetalol, nifedipine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pre-Eclampsia, Depression
Preeclampsia Research on Vitamin D, Inflammation, & Depression
This study is designed to comprehensively investigate the anti-inflammatory role of vitamin D in reproductive aged women, and its association with preeclampsia and depression.
- Conditions
- Pre-Eclampsia, Depression, Inflammation, Vitamin D Deficiency
- Trial name
- PROVIDE (NCT03018132)
- Testing
- mental health screening, education and referral program
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Vitamin D Deficiency, Pre-Eclampsia
Effect of Vitamin D3 Supplementation in Pregnancy on Risk of Pre-eclampsia
Vitamin D deficient pregnant ladies were selected and randomized into 2 groups for routine daily dose of multivitamin (400IU vitamin D3) versus maximum safest treatment daily dose (4000IU vitamin D3).
- Trial name
- NCT03101150
- Testing
- 400 IU Vitamin D3, 4000 IU Vitamin D3
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Prehypertension, Hypertension
Nebivolol and Endothelial Regulation of Fibrinolysis (NERF)
The investigators hypothesize that nebivolol will improve endothelial t-PA release in adult humans with elevated blood pressure to a greater extent than either metoprolol or placebo.
- Trial name
- NCT01595516
- Testing
- Nebivolol, Metoprolol, Bradykinin
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Preeclampsia, Recurrence
Effects of Recurrent PE on Women and Offspring
The purpose of this study is to evaluate the risk factors of recurrent preeclampsia and compare the short-term and long-term adverse outcomes of women and their offspring.
- Conditions
- Preeclampsia, Recurrence, Hypertension
- Trial name
- RPOH (NCT05134285)
- Testing
- blood pressure,BMI, blood sample
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Dunjin Chen
Preeclampsia (PE)
Prevention of Preeclampsia in Denmark: A National Implementation Study
The goal of this clinical study is to learn if a new first-trimester screening program can better find pregnant women who are at high risk of developing preeclampsia and help prevent the condition with early treatment.
- Trial name
- PREPRED (NCT07485140)
- Testing
- First trimester screening for preeclampsia
- Where
- 3 sites in Denmark
- Volunteers
- 80,000 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
Preeclampsia, Preterm Birth
Prediction of Preeclampsia and Other Pregnancy Complications Following Combined Iterative Screening
Preterm birth (PTB), preeclampsia (PE), fetal growth restriction (FGR) and intra-uterine fetal death (IUFD) constitutes the main causes of perinatal morbidity and mortality and are called "Great Obstetrical Syndromes".
- Conditions
- Preeclampsia, Preterm Birth, Fetal Growth Restriction, Intra Uterine Fetal Death
- Trial name
- PREDICTION2 (NCT03067298)
- Where
- Canada
- Volunteers
- 805 people, healthy volunteers welcome
- Sponsor
- Emmanuel Bujold
Overweight, Obesity
Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study
The Fit2Play prospective cohort study examines the effects of a park-based youth physical activity afterschool program on youth participant fitness and mental health outcomes.
- Conditions
- Overweight, Obesity, Hypertension, Prehypertension
- Trial name
- F2P (NCT06595251)
- Testing
- Fit2Play curriculum
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Airway Assessment
Ultrasonographical Assessment of Airway Indices in Pregnancy
Clinical and ultrasound indices of airway, in addition to laryngoscopic view will be assessed and compared among three groups of patients: non pregnant, pregnant with normal blood pressure, preeclampsia patients undergoing…
- Trial name
- NCT07423741
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- South Valley University
Pregnancy, Preeclampsia
Impact of Particulate Matter on Mothers and Babies in Antwerp (IPANEMA)
Introduction: An emerging body of evidence indicates that there is an association between air pollution exposure in pregnancy and adverse pregnancy outcomes (Rudra, Williams, Sheppard , Koenig, \& Schiff, 2011; Dadvand, et al.…
- Trial name
- IPANEMA (NCT02592005)
- Testing
- amount of fine dust and other environmental exposure
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Preeclampsia, Gestational Hypertension
Heart Health 4 New Moms: A Randomized Trial in the First Year After Preeclampsia
Preeclampsia causes devastating maternal and neonatal morbidity and mortality with a high recurrence risk and a rapid, occult progression to cardiovascular disease after delivery.
- Conditions
- Preeclampsia, Gestational Hypertension, Hypertension, Obesity
- Trial name
- HH4NM (NCT03749746)
- Testing
- Home Blood Pressure Monitoring, Heart Health 4 New Moms, Usual care
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Blood Pressure
Pre-conception Interventions to Reduce Blood Pressure Before Pregnancy
The study proposes to evaluate the feasibility of a preconception intervention comprising two proven interventions for reducing blood pressure; Beetroot juice; a source of dietary nitrate which reduces BP by 8/4mmHg after 4…
- Trial name
- CONCEIVE 2 (NCT05299450)
- Testing
- Beet It shots, Exercise, Control group
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Preeclampsia, Premature Birth
Cohort Study on the Levels of Placental Growth Factor and Nucleosomes in Early Pregnancy and Adverse Pregnancy Outcomes
Objective: This study aims to investigate the association between maternal serum placental growth factor (PLGF) and nucleosome levels in early pregnancy and adverse pregnancy outcomes, and to evaluate their predictive value for…
- Conditions
- Preeclampsia, Premature Birth, Fetal Growth Restriction, Recurrent Miscarriage
- Trial name
- NCT07841197
- Testing
- Measurement of plasma nucleosome and placental growth factor (PLGF) levels
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Blood Pressure
Clinical Evaluation of the Performance of Bionet Sphygmomanometer Modules Based on Protocol Presented by the International Organization for Standardization
According to INTERNATIONAL STANDARD (hereafter ISO) blood pressure (BP) monitor clinical evaluation protocol (ISO 81060-2:2018, Non-invasive sphygmomanometers- Part2: Clinical investigation of intermittent automated measurement…
- Trial name
- NCT06609486
- Testing
- Blood pressure measurement group
- Where
- South Korea
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hoon-Ki Park
Health, Subjective, Healthy
Prevalence of Sedentary Lifestyle, Pre-hypertension, and Obesity
Hypertension has been a serious problem among people from different ages in the last few decades, so by taking this in consideration we decided to search for specific risk factors that cause hypertension in young healthy adults…
- Trial name
- NCT05629351
- Testing
- Observational Group
- Where
- Turkey (Türkiye)
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Hypertension,Essential, Exercise Activity
Effect of High-Intensity Interval Training Compared to Hydrochlorothiazide on Ambulatory Blood Pressure
The number of persons with hypertension is increasing and with it the number of related cardiovascular events and related functional or cognitive declines.
- Trial name
- DIISCCO (NCT04103411)
- Testing
- 24h-Ambulatory Blood Pressure
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Anil Nigam
Prehypertension
Diet and Exercise on Ambulatory Blood Pressure
This is a multicenter, randomized, single-blinded clinical trial investigating the effect of dietary management and active aerobic exercise training on reduction of 24-hour ambulatory blood pressure in subjects with…
- Trial name
- NCT05274971
- Testing
- Active dietary management and aerobic exercise training.
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Pre-Eclampsia
Role of ASpirin in Placental and Maternal Endothelial Cell Regulation IN Pre-eclampsia
Endothelial dysfunction and defective placental vascularization are hypothesized to be significant causes of preeclampsia. In preeclampsia, due to vascular endothelial dysfunction, vasoconstriction and platelet activation can…
- Trial name
- ASPERIN (NCT03893630)
- Testing
- Acetylsalicylic Acid 81 mg, Acetylsalicylic Acid 162 mg, Control
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- John O'Brien, MD
Pre-Eclampsia
Preeclamptic Patients and Pentraxin 3 & Lipoprotein-associated Phospholipase A2
In particular, pentraxine 3 (PTX3) molecule was assumed to have a prognostic value in acute myocardial infarction.In patients affected by acute myocardial infarction, early plasma elevation of PTX3 appears to predict a worse…
- Trial name
- NCT04239352
- Testing
- Pentraxin 3 ; new biomarker, Lipoprotein-associated phospholipase A2 ; new biomarker
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital