Clinical trials: Prebiotic
Temperament, Sleep
GUTLINK4KIDS Intervention
This study aims to investigate the chronic effects of prebiotic consumption on cognitive, behavioural and gut microbiome outcomes in children aged 3-5 years.
- Conditions
- Temperament, Sleep, Cognition, Emotion Regulation
- Trial name
- GUTLINK4KIDS (NCT07401212)
- Testing
- Prebiotic powder
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Reading
Hypertension, Hyperglycemia
Effect of Dietary Fiber on Metabolic Syndrome, Gastrointestinal Function, Mood and Sleep Quality in Obese People
Metabolic syndrome includes hypertension(high blood pressure), hyperglycemia(high blood suger), dyslipidemia(abnormal blood lipid level) and obesity.
- Conditions
- Hypertension, Hyperglycemia, Dyslipidemia, Obesity
- Trial name
- NCT06626867
- Testing
- Dietary Fiber Supplementation
- Where
- Taiwan
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Chien-Wen Hou
Healthy
A Study to Evaluate the Effect of Diet on the Tolerability of FOS in Healthy Volunteers
The primary objective of this study is to determine the 5-day tolerability of one commercially available prebiotic food ingredient, FOS, in healthy human subjects with and without diet control.
- Trial name
- NCT02628678
- Testing
- FOS
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Kaleido Biosciences
Obesity, Metabolic Syndrome
Role of Colonic Events on Metabolism and Appetite Control: A Synbiotic Approach
The purpose of the study is to evaluate food factors related to colonically derived regulation of glucose metabolism (and related parameters) and satiety using a semi-acute meal study in healthy subjects as experimental model.
- Trial name
- NCT01718418
- Testing
- test meal, reference
- Where
- Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Lund University
Hypercholesterolemia, Flatulence
Fabulous Fibre Study - Effect of Wheat Bran Extract on Gut and General Health in Healthy Aging Subjects (FFS)
This is a placebo controlled, cross-over, randomized, double blinded study. The intervention food products will be taken as diet prebiotic supplements: 1.
- Conditions
- Hypercholesterolemia, Flatulence, Intestinal Diseases
- Trial name
- FFS (NCT02693782)
- Testing
- Fibre supplement
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Gut Microbiome, Prebiotic
ZOE BIOME Study: Biotics Influence on Microbiome Ecosystem
The differences observed in host gut microbiome communities between health and disease states, and between different dietary patterns, has led to an increase in the use of dietary modulations to influence microbiome composition…
- Conditions
- Gut Microbiome, Prebiotic, Probiotic, Postprandial Period
- Trial name
- NCT06231706
- Testing
- Prebiotic-like nut and seed mix, Bread Crouton, Probiotic capsule
- Where
- United Kingdom
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- King's College London
Sarcopenia, Frailty
Protein and Skeletal Muscle in Older Twins: Role of the Gut Microbiome
Research Question: Does the gut microbiome contribute to muscle anabolic resistance to protein supplementation in older adults? Background: Loss of muscle occurs with age and skeletal muscle in older adults can display anabolic…
- Conditions
- Sarcopenia, Frailty, Age-Related Sarcopenia
- Trial name
- PROMOTe (NCT04309292)
- Testing
- Prebiotic food supplement, Protein supplement
- Where
- United Kingdom
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- King's College London
Birth Weight <2500gm, Genitourinary Tract Infection
Prebiotic in Preventing Low Birth Weight
More than 20 million infants worldwide, representing 16 per cent of all births, are born with low birth weight, 96 per cent of them in developing countries.
- Trial name
- NCT02721225
- Testing
- Fructooligosaccharide, Pocari-Sweat
- Where
- Bangladesh
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Olipop, Poppi
Impact of Prebiotic Sodas on Satiety and Metabolic Responses in Healthy Men
The study aims to study healthy men aged 18-40 to explore how different beverages affect hunger, blood sugar, insulin, and a hormone called GLP-1, which helps regulate appetite and blood sugar.
- Conditions
- Olipop, Poppi, Coca Cola - Classic, Diet Coke
- Trial name
- NCT07105826
- Testing
- Prebiotic Soda 1, Prebiotic Soda 2, Diet Soda
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Sleep Disturbance, Fatigue Syndrome, Chronic
Bao Yuan Tang Extract and Galactooligosaccharides for Sleep Regulation
Certain classical formulas in traditional Chinese medicine and dietary prebiotics have demonstrated beneficial effects on various aspects of suboptimal health status in previous studies.
- Conditions
- Sleep Disturbance, Fatigue Syndrome, Chronic, Endocrine Disorder, Glucose Metabolism Disorder
- Trial name
- NCT07774897
- Testing
- Combination product (Bao Yuan Tang full-component extract 2.0g and galactooligosaccharides 2.0g), Galactooligosaccharides 2.0g
- Where
- 6 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Exercise Endurance
Synbiotic Supplementation in Cyclists
The goal of this clinical trial is to assess the efficacy of a synbiotic blend on exercise performance and other exercise parameters in trained adult cyclists.
- Trial name
- NCT06300060
- Testing
- Synbiotic
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Intestinal Diseases
The Prebiotic Effect of Daily Intake of Orange Juice Affects the Bioavailability of Flavanones?
This study aimed investigate the chronic effect of orange juice consumption on gut microbiota and in the bioavailability of flavanones and metabolites by feces, blood and urine analysis.
- Trial name
- NCT03032861
- Testing
- Orange juice
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Healthy, Gastrointestinal Diseases
Prebiotic Effects on Gut Microbiota, Gut Comfort and Immune Function
Human Milk Oligosaccharides (HMOs) are the third most abundant class of nutrients in human milk. Studies investigating the effects of dietary HMOs in infants have shown various health and developmental benefits such as the…
- Trial name
- NCT06094153
- Testing
- HMO 1, HMO 2
- Where
- Singapore
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kyowa Hakko Bio Co., Ltd.
Mood
Effects of Prebiotics on Intestinal Colonization and Mood in a University Cohort
There is a growing interest within the scientific community of whether prebiotics can aid in clinical outcomes including mood via modulation of the gut microbiota and its resulting metabolites via the gut-brain axis.
- Trial name
- NCT05212545
- Testing
- Prebiotic supplement, Prebiotic combination, Prebiotic oligosaccharides
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
Gut Health, Gastrointestinal Diseases
Improved Gut Health Outcomes Associated With Probiotics Fortified With Hydrolyzed Whey Protein in Infant Formula
The goal of this interventional clinical trial is to test the effectiveness of improving gut health in terms of frequency of bowel movements in newly born infants fed with Feihe investigational formula product containing…
- Trial name
- NCT06159088
- Testing
- Feihe Investigational Formula, Control Formula, Breastfeeding
- Where
- 3 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Heilongjiang Feihe Dairy Co. Ltd.
Constipation, Gastrointestinal Discomfort
Clinical Evaluation of the Effects of EpiCor on Digestive Comfort
Previous in vitro studies suggest that EpiCor is well fermented in the colon and has prebiotic potential. The repeated long-term administration of low doses of EpiCor in the Simulator of the Human Intestinal Microbial Ecosystem…
- Trial name
- NCT03051399
- Testing
- EpiCor
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ProDigest
Healthy
Effect of Fructose on Colonic Microflora
Fructose is the principal carbohydrate in fruits and is added to many food products. This 6 carbon sugar is associated with a number of ill effects, like promotion of high triglycerides,precipitation of gout in men,possible…
- Trial name
- MEF (NCT00775567)
- Testing
- Fructose powder
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
T Cell Response to Dried Plum, Vitamin D Influence on Immune Response
Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women
Prior studies have shown that dietary supplementation with dried plums (also known as prunes) reduces bone loss in postmenopausal women.
- Conditions
- T Cell Response to Dried Plum, Vitamin D Influence on Immune Response, Dried Plum and Immune Function
- Trial name
- NCT07222111
- Testing
- Dried plums
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Anemia, Iron-Deficiency
Iron Absorption From a Micronutrient Powder Containing Galacto-oligosaccharides (GOS)
Infants and young children in sub-Saharan Africa have high rates of iron deficiency anemia (IDA), which adversely affects their growth and cognitive development.
- Trial name
- FeGOS (NCT02666417)
- Testing
- Fortified maize porridge (MNP+iron), Fortified maize porridge (MNP+iron+GOS)
- Where
- Kenya
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Gut Microbiota
The Effect of Prebiotic Synergy1 Supplementation on Microbiota, Protein Metabolism and Gastrointestinal (GI) Symptoms in People Consuming High Protein Diet
The composition and metabolism of human gut microbiota play crucial roles in health. Microbial colonisation of the gastrointestinal tract varies widely, with the large intestine having not only the highest density of microbes in…
- Trial name
- ITF (NCT02827760)
- Testing
- Synergy1, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Reading