Clinical trials: Preeclampsia Postpartum
Postpartum Infection
Trends in Pregnancy Outcomes Beyond Twenty Weeks Gestational Age in Assisted Reproductive Technology Conceived Pregnancies in British Columbia
Examining outcomes beyond 20 weeks gestational age in pregnancies conceived by ART compared to spontaneously conceived pregnancies 1.
- Trial name
- NCT06726603
- Testing
- Assisted Reproductive Technology
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Preeclampsia
Balance of Angiotensin II Receptors in Vessel Function After Preeclampsia
Otherwise healthy women who develop preeclampsia during pregnancy are more likely to develop and die of cardiovascular disease later in life.
- Trial name
- NCT06157580
- Testing
- Compound 21, Angiotensin II
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Postpartum Hemorrhage, Postpartum Depression
Postpartum Video Education in High Risk Populations
This is a prospective, single-center, randomized control study to determine if video education at the time of postpartum discharge improves patient knowledge on the warning signs for the top three causes of severe maternal…
- Conditions
- Postpartum Hemorrhage, Postpartum Depression, Postpartum Sepsis, Postpartum Preeclampsia
- Trial name
- NCT06310720
- Testing
- Video Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Preeclampsia
Post-Pregnancy Cardio Trial
Preeclampsia is a systemic pregnancy disorder and is associated with an increased cardiovascular risk later in life. This study will characterize myocardial tissue in patients after preeclampsia compared to controls and…
- Trial name
- PPC1 (NCT03313063)
- Where
- Germany
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Preeclampsia With Severe Features
Use of Cheetah® Cardiac Monitoring System to Guide Discontinuation of Magnesium Sulfate in Women With Severe Preeclampsia
This is a single site pilot randomized, controlled, trial randomizing patients with PE with severe features to one of 2 groups: 24 hours of postpartum magnesium sulfate (current arbitrary standard of care) Using the Cheetah®…
- Trial name
- NCT04474704
- Testing
- Cheetah® non-invasive cardiac monitoring system, Standard of care
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Preeclampsia Postpartum
Sensitivity of Angiotensin II Type II Receptors in Women Following Preeclampsia
Women who develop preeclampsia during pregnancy are more likely to develop and die of cardiovascular disease later in life, even if they are otherwise healthy.
- Trial name
- NCT05937841
- Testing
- Compound 21
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Hypertension in Pregnancy, Gestational Diabetes
Reshaping Postpartum Follow-up
The aim of this study is to evaluate the impact of personalized postpartum follow-up cards on completion of postpartum health related tasks. The intervention will consist of a card given to patients at time of discharge.
- Conditions
- Hypertension in Pregnancy, Gestational Diabetes, Cervical Dysplasia
- Trial name
- NCT06054841
- Testing
- Postpartum follow up card, Control
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Hypertension
Prevention of Severe Postpartum Hypertension
The purpose of this study is to determine whether postpartum administration of furosemide to women with antepartum hypertensive disorders (gestational hypertension, preeclampsia) or elevated blood pressure in the first 24 hours…
- Trial name
- NCT02450773
- Testing
- Furosemide, Potassium chloride
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Puerperal Sepsis, Postpartum Hemorrhage
Assessing Childbirth-related Complications at the Community Level in Kenya
Kenya is one of the countries in sub-Saharan Africa that still experience high maternal mortality. For instance, in 2008/09 maternal mortality ratio was estimated to be 488/100,000 live births.
- Conditions
- Puerperal Sepsis, Postpartum Hemorrhage, Preeclampsia and Eclampsia, Retained Placenta, Without Hemorrhage
- Trial name
- NCT01665456
- Where
- Kenya
- Volunteers
- 585 people, healthy volunteers welcome
- Sponsor
- Wilson Liambila
Pre-Eclampsia, HELLP Syndrome
Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe Features
NSAIDs, specifically cyclo-oxygenase (COX) inhibitors, are known to increase blood pressure over time in non-pregnant adults, but the effect of COX-inhibitors on blood pressure in the setting of preeclampsia have not been well…
- Conditions
- Pre-Eclampsia, HELLP Syndrome, Eclampsia
- Trial name
- NCT02911701
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Preeclampsia, Microvascular Function
Prenatal Aspirin and Postpartum Vascular Function
Preeclampsia is a pregnancy disorder affecting ~5-10% of pregnancies in the United States. Women who develop preeclampsia during pregnancy are more likely to develop and die of cardiovascular disease later in life, even if they…
- Trial name
- NCT05653973
- Testing
- Acetylcholine, Endothelin-1
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Preeclampsia, Gestational Hypertension
Postpartum NSAIDS and Maternal Hypertension
Previous studies have suggested that NSAID use causes an increase in blood pressure. Further, blood pressure elevation has been noted in women with pregnancy related hypertensive disease during the postpartum period.
- Conditions
- Preeclampsia, Gestational Hypertension, Superimposed Preeclampsia, Chronic Hypertension in Obstetric Context
- Trial name
- NCT03824119
- Testing
- Ibuprofen 600 mg, Standard Postpartum Care without NSAIDs
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Patient Satisfaction
Patient Satisfaction With Abbreviated Postpartum Magnesium Sulfate for Severe Preeclampsia
Preeclampsia is a common and potentially devastating disease that affects only pregnant or postpartum patients. It is a leading cause of maternal mortality not only worldwide, but in the United States as well.
- Trial name
- NCT05789381
- Testing
- Magnesium sulfate
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Post Partum Severe Preeclampsia
Magnesium Sulfate During the Postpartum in Women With Severe Preeclampsia
There is no evidence that patients receiving magnesium sulfate before birth are required to maintain the drug for 24 hours. Therefore the investigators will have a randomized clinical study in patients with severe preeclampsia…
- Trial name
- MAG-PIP (NCT02307201)
- Testing
- Magnesium Sulfate
- Where
- 9 sites in Dominican Republic, Ecuador and 3 more
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Dr. Arnulfo Arias Madrid
Cardiovascular Disease, Preeclampsia
Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia
This study will compare two arms in a randomized clinical trial of cardiovascular risk prevention in women with a history of preeclampsia.
- Conditions
- Cardiovascular Disease, Preeclampsia, Hypertension, Post-partum Weight Retention
- Trial name
- HH4M (NCT02147626)
- Testing
- Web-based educational and motivational modules, Information and Screening Group
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital