Clinical trials: Prefrail
Frailty
Effects of Low-Speed and High-Speed Resistance Training Programs on Frailty Status
The present study refers to a three-arm randomized controlled trial that investigated the effects of two types of RT on frailty status, physical performance, cognitive function, and blood pressure of prefrail and frail older…
- Trial name
- RTF (NCT04868071)
- Testing
- Physical Exercise
- Where
- 2 sites in Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Cognitive-prefrailty, Prefrailty
The Cognitive-Prefrail Syndrome and Its Association With Adverse Health Outcomes
Lay Summary Older adults who are prefrail (an intermediate, potentially reversible stage between robustness and frailty) with early symptoms of cognitive impairment are a segment of the population that have hitherto remained…
- Conditions
- Cognitive-prefrailty, Prefrailty, Motoric Cognitive Risk Syndrome
- Trial name
- NCT04240028
- Testing
- Data Collection
- Where
- Canada
- Volunteers
- 1,741 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Frailty, Motoric Cognitive Risk Syndrome
Cognitive Prefrail and Frailty, and Motoric Cognitive Risk Syndrome: Prevalence and Association With Incident Adverse Health Events
We defined a new and early condition in the spectrum of cognitive frailty: the "cognitive-prefrailty" which is a combination of prefrailty stage and subjective cognitive impairment (SCI).
- Conditions
- Frailty, Motoric Cognitive Risk Syndrome, Cognitive-prefrailty
- Trial name
- NCT04275817
- Testing
- Data collection
- Where
- Canada
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Frailty, Inflammation
Fighting Immunosenescence and Promoting Immunity by a Fasting-mimicking Diet Elderly.
Background: Immunosenescence is an aging-dependent phenomenon underlying age dependent deterioration in the function of the immune system, characterized by a decline in B and T cells with a relative increase in natural killer…
- Conditions
- Frailty, Inflammation, Immune System Disorder
- Trial name
- NCT04928963
- Testing
- Prolon - FMD
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Genova
Healthy Young Adults, Prefrail Elderly
GOS and Microbial Fermentation in Aging
The population is aging worldwide, concomitant frailty is increased in older age groups. Frailty has a strong impact on outcomes of multi-morbidity and daily living, thereby negatively influencing quality of life and health care…
- Trial name
- NCT03077529
- Testing
- Galacto-oligosacchride, Maltodextrin
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Inflammatory Response
Effects of Metformin in a Non-Diabetic Patient Population
Metformin has a well-established safety profile and it has become clear that metformin has additional salutary effects, including anti-inflammatory, anti-aging, and anti-thrombotic properties.
- Trial name
- NCT03772964
- Testing
- MetFORMIN Hydrochloride ER
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Brian Zuckerbraun
Elderly, Functional Status
Connecting Emergency Departments With Community Services to Prevent Mobility Losses in Pre-frail & Frail Seniors
About 18% of independent people over 65 who are evaluated in Emergency Departments for minor injuries (fractures, sprains) present some mobility decline up to 3 to 6 months postinjury.
- Trial name
- CEDeComS (NCT03991598)
- Testing
- Exercise program
- Where
- 6 sites in Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval