Clinical trials: Prefrail Elderly
Elderly, Functional Status
Connecting Emergency Departments With Community Services to Prevent Mobility Losses in Pre-frail & Frail Seniors
About 18% of independent people over 65 who are evaluated in Emergency Departments for minor injuries (fractures, sprains) present some mobility decline up to 3 to 6 months postinjury.
- Trial name
- CEDeComS (NCT03991598)
- Testing
- Exercise program
- Where
- 6 sites in Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Frailty
Effects of Low-Speed and High-Speed Resistance Training Programs on Frailty Status
The present study refers to a three-arm randomized controlled trial that investigated the effects of two types of RT on frailty status, physical performance, cognitive function, and blood pressure of prefrail and frail older…
- Trial name
- RTF (NCT04868071)
- Testing
- Physical Exercise
- Where
- 2 sites in Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Frailty, Inflammation
Fighting Immunosenescence and Promoting Immunity by a Fasting-mimicking Diet Elderly.
Background: Immunosenescence is an aging-dependent phenomenon underlying age dependent deterioration in the function of the immune system, characterized by a decline in B and T cells with a relative increase in natural killer…
- Conditions
- Frailty, Inflammation, Immune System Disorder
- Trial name
- NCT04928963
- Testing
- Prolon - FMD
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Genova
Inflammatory Response
Effects of Metformin in a Non-Diabetic Patient Population
Metformin has a well-established safety profile and it has become clear that metformin has additional salutary effects, including anti-inflammatory, anti-aging, and anti-thrombotic properties.
- Trial name
- NCT03772964
- Testing
- MetFORMIN Hydrochloride ER
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Brian Zuckerbraun
Healthy Young Adults, Prefrail Elderly
GOS and Microbial Fermentation in Aging
The population is aging worldwide, concomitant frailty is increased in older age groups. Frailty has a strong impact on outcomes of multi-morbidity and daily living, thereby negatively influencing quality of life and health care…
- Trial name
- NCT03077529
- Testing
- Galacto-oligosacchride, Maltodextrin
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center