Clinical trials: Pregabalin
Healthy
An Investigation of the Effects of Erythromycin on the Pharmacokinetics of the Pregabalin Controlled Release Tablet
The purpose of this study is to 1) evaluate the extent of absorption of a single dose of a pregabalin controlled release tablet with and without coadministration of erythromycin and 2) evaluate the safety and tolerability of a…
- Trial name
- NCT01342198
- Testing
- Pregabalin controlled release, 330 mg, erythromycin
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Peripheral Neuropathic Pain
Gabapentin and Pregabalin Effects on Inflammation and Cardiac Function in Peripheral Neuropathic Pain
This prospective, controlled, observational cohort study will evaluate short-term changes in inflammatory biomarkers and subclinical cardiac function in adults with peripheral neuropathic pain who are prescribed gabapentin or…
- Trial name
- NCT07755514
- Testing
- Gabapentin, Pregabalin
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Giresun University
Anxiety State, Sedation
Pre-emptive Pregabalin on Attenuating Maternal Anxiety And Stress Response To Intubation During Caesarean Section
There is exaggerated neuroendocrine stress response to laryngoscopy and endotracheal intubation during the Induction to anesthesia-delivery (I-D) period under light anesthesia.
- Trial name
- NCT04622202
- Testing
- Pregabalin 150mg, multivitamin
- Where
- Egypt
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Healthy
Pharmacokinetic Drug Interaction Between Pregabalin and Thioctic Acid.
A randomized, open-label, six-sequence, three-period, three-treatment, multiple dosing clinical trial to investigate the pharmacokinetic drug interaction between Pregabalin and Thioctic acid after oral administration in healthy…
- Trial name
- NCT01808300
- Testing
- Pregabalin 300mg, Thioctic acid 600mg
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Unimed Pharmaceuticals
Anxiety Disorders
PharmacofMRI of Anxiolytic Medications (Pregabalin)
The purpose of this study is to use functional magnetic resonance imaging (fMRI) in healthy controls to examine the acute effects of certain anxiolytic medications on brain function.
- Trial name
- NCT00706836
- Testing
- Pregabalin 50mg, Pregabalin 200 MG
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Diabetic Peripheral Neuropathy (DPN)
Thymoquinone as an add-on Therapy for the Management of Patients With Diabetic Peripheral Neuropathy
The goal of this clinical trial is to evaluate the efficacy of thymoquinone as an adjuvant treatment with pregabalin in the management of diabetic peripheral neuropathy for both sexes older than 18 years.
- Trial name
- TQDPN (NCT07313111)
- Testing
- stander treatment pregabalin, thymoquinone
- Where
- Iraq
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Abuse Potential
Study Evaluating Abuse Potential of Lyrica® in Healthy Non-Drug Dependent Recreational Opioid Users
This is a Phase 4 clinical study in healthy non-drug dependent recreational opioid users to assess the abuse potential of Lyrica when taken alone or in combination with oxycodone.
- Trial name
- NCT05053126
- Testing
- Pregabalin 300mg, pregabalin 450 mg, Pregabalin 300 mg with oxycodone 20 mg
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Viatris Specialty LLC
Healthy
Bioequivalence Study of Two Formulations of Pregabalin Capsules 150 mg
The present study was conducted to find out whether the bioavailability of 150 mg pregabalin capsules produced by Dexa Medica was equivalent to the reference products (Lyrica® capsule 150 mg, Pfizer Manufacturing Deutschland…
- Trial name
- NCT02233777
- Testing
- Pregabalin capsules 150 mg of Dexa Medica, Pregabalin capsules 150 mg of Pfizer Manufacturing Deutschland
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dexa Medica Group
Pain
The Effect of Pregabalin and Dexamethasone on Acute and Chronic Pain After Lumbar Spinal Surgery
Multimodal analgesia may be important for optimal postoperative pain treatment and facilitation of early mobilization and recovery.
- Trial name
- NCT01168531
- Testing
- Pregabalin, dexamethasone
- Where
- South Korea
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Breast Cancer, Hot Flashes
Pregabalin in Treating Women With Hot Flashes
RATIONALE: Pregabalin may help relieve hot flashes in women with a history of breast cancer or those who have no history and do not wish to take estrogen therapy for fear of increased risk of breast cancer.
- Trial name
- NCT00702949
- Testing
- pregabalin
- Where
- 209 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Herpes Zoster, Postherpetic Neuralgia
Study to Find Out if Therapy With the Drug Pregabalin Relieves Pain During Shingles Compared With Placebo
The purpose of this study is to see if therapy with the drug pregabalin relieves pain during shingles compared with placebo. A placebo is an inactive substance.
- Trial name
- NCT00352651
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Postoperative Pain, Opioid Use
Trial of Pregabalin for Post-operative Pain in Women Undergoing Abdominal Hysterectomy
We hypothesize that pregabalin will decrease post-operative pain scores and opioid use following abdominal hysterectomy compared to placebo.
- Trial name
- NCT00781131
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Pain
Pregabalin and Remifentanil - Analgesia and Ventilation
In this experimental study on healthy volunteers we explored the effect of pregabalin alone and in combination with remifentanil on acute experimental pain and ventilatory function.
- Trial name
- NCT01419405
- Testing
- Pregabalin, Remifentanil, sugar pill, saline infusion
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Fibromyalgia
Brain Response to Single Dose of Pregabalin in Fibromyalgia
Fibromyalgia syndrome represents a "spectrum disorder" characterized by widespread chronic pain, fatigue, sleep disturbances, mood and cognitive alterations.
- Trial name
- NCT02639533
- Testing
- Pregabalin
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Rotator Cuff Tears, Central Sensitisation
Effect of Pregabalin on Shoulder Pain in Patients With Central Sensitization After Arthroscopic Rotator Cuff Repair
This study aims to investigate the effects of Pregabalin intake on shoulder pain management in patients with central sensitization undergoing arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Central Sensitisation, Neuropathic Pain
- Trial name
- NCT06367998
- Testing
- Pregabalin
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Healthy
Assessment of the Analgesic Effects of PF-05089771 and Pregabalin in Healthy Volunteers Using Evoked Pain Endpoints
This study will examine the activity of PF-05089771 and pregabalin, alone and in combination on a panel of evoked pain tests carried out from 0.5 to 10 hours following oral dosing in healthy male subjects
- Trial name
- NCT02349607
- Testing
- PF-05089771 300mg, PF-05089771 300 mg + pregabalin 300 mg, pregabalin 300 mg
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
An Investigation Of The Absorption And Pharmacokinetics Of A Single Dose Of A Controlled Release (CR) Pregabalin Tablet Following A Low, Medium, And High-Fat Evening Meal As Compared To A Single Dose Of The Immediate Release (IR) Pregabalin Capsule In Healthy Volunteers
The purpose of this study is to 1) evaluate the extent of absorption of a single dose of a pregabalin controlled release tablet following either a low, medium, or high-fat evening meal as compared to a single dose of the…
- Trial name
- NCT01257529
- Testing
- Pregabalin controlled release, 330 mg, low-fat, Pregabalin controlled release, 330 mg, medium-fat, Pregabalin controlled release, 330 mg, high-fat
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain Detection, Pain Threshold
Pharmacodynamic Study of 300mg Pregabalin vs Placebo in Healthy Male Adults
This is a randomized, double-blind, placebo-controlled within-participant crossover study in healthy male participants 18-55 years of age to assess pain tolerance during a cold pressor test.
- Trial name
- NCT06600607
- Testing
- pregabalin 300 mg
- Where
- New Zealand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Latigo Biotherapeutics
Sleep Disorder
Improving Perioperative Sleep Disorders
In today's day of increasing surgical volume, perioperative sleep disorders are an issue that cannot be ignored. They are an important component of perioperative brain protection.
- Trial name
- NCT06512155
- Testing
- Pregabalin, Zolpidem
- Where
- China
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Mengchang Yang
Healthy
A Clinical Trial to Compare The Pharmacokinetics of A Pregabalin GLARS Tablet 150mg With Immediate Release Formulation and to Assess The Effect of High Fat Diet in Healthy Male Subjects
The purpose of this clinical trial is to compare the pharmacokinetic characteristics of GLA5PR GLARS tablet 150mg and Lyrica Capsule 75mg.
- Trial name
- GLA5PR-101 (NCT01635751)
- Testing
- Pregabalin
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation