Clinical trials: Pregabalin
Taxane, Drug-related Side Effects and Adverse Reactions
Exploratory Study on the Use of Pregabalin for the Treatment of Taxol Related Arthralgia-Myalgia
Paclitaxel is chemotherapeutic agent used in many of the most common anti-cancer regimens. Its use is frequently associated with moderate to severe muscle and joint pain that may persist for several days after the treatment.
- Conditions
- Taxane, Drug-related Side Effects and Adverse Reactions, Pain, Breast Cancer
- Trial name
- NCT02024568
- Testing
- Pregabalin
- Where
- Israel
- Volunteers
- 38 people
- Sponsor
- Assaf-Harofeh Medical Center
Diabetic Peripheral Neuropathic Pain
To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Diabetic Peripheral Neuropathic Pain
Investigate the efficacy and safety of HSK16149 capsules in Chinese diabetic peripheral neuropathic pain (DPNP) following 13 weeks treatment in comparison to placebo.
- Trial name
- NCT04647773
- Testing
- HSK16149 20mg BID, HSK16149 40mg BID, HSK16149 60mg BID
- Where
- China
- Volunteers
- 687 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Breast Cancer Surgery, Post Operative Pain
The Effects of Peri-Operative Pregabalin on Post-Operative Pain Following Breast Cancer Surgery With Axillary Node Dissection: A Pilot Study
Breast cancer is a devastating disease. Some women with breast cancer undergo surgery to remove the breast and lymph nodes in the axilla (armpit).
- Trial name
- NCT00852683
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Nova Scotia Health Authority
Chronic Postsurgical Pain
The Effect of Esketamine Combined With Pregabalin on Chronic Postsurgical Pain in Patients After Craniotomy.
Chronic postsurgical pain (CPSP), which is one of the most common and serious long term complication of surgery，occurs in approximately 10% of patients after a surgical procedure.
- Trial name
- NCT05160493
- Testing
- S-ketamine and pregabalin
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Beijing Tiantan Hospital
Fibromyalgia
Fixed Versus Flexible Dosing of Pregabalin in Patients With Fibromyalgia
A 9-week randomized double-blind, multi-center study of 172 patients, who after 1 week baseline evaluation are randomized to either fixed dose pregabalin starting at 75 mg BID for one week and increased to 150 mg BID for 7 weeks…
- Trial name
- Flexdose (NCT01226667)
- Testing
- Pregabalin
- Where
- 5 sites in United States
- Volunteers
- 174 people
- Sponsor
- Osteoporosis Medical Center, Beverly Hills, CA
Epilepsies, Partial
Vision Testing in Patients With Partial Seizures Receiving Either Lyrica or Placebo
Patients with partial seizures currently taking 1-3 antiepileptic medications will have a 50:50 chance to receive Lyrica 300 mg per day or placebo (no active ingredients) added on to their current medications for 3 months.
- Trial name
- NCT00351611
- Testing
- Lyrica (pregabalin)
- Where
- 150 sites in United States, Bulgaria and 7 more
- Volunteers
- 187 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Persistent Postoperative Pain
Swiss Multi-centre, Randomized, Placebo Controlled Trial of Pregabalin for Prevention of Persistent Pain in High Risk Patients Undergoing Breast Cancer Surgery
This study will test the benefits and risks of using pregabalin perioperatively to prevent persistent postoperative pain in patients at high risk (>30%) of developing such pain after breast cancer surgery.
- Trial name
- PREVENT (NCT03216187)
- Testing
- Pregabalin
- Where
- 6 sites in Switzerland
- Volunteers
- 126 people
- Sponsor
- Benno Rehberg-Klug
Breast Cancer, Lymphoma
Trial of Pregabalin for Granulocyte Colony-stimulating Factor (GCSF)-Induced Bone Pain
Purpose: To evaluate the preventative effects of pregabalin on pegfilgrastim-induced bone pain in cycle 1. Because granulocyte colony stimulating factor (G-CSF) receptors are found at nerve endings which modulate the pain signal…
- Conditions
- Breast Cancer, Lymphoma, Pain
- Trial name
- NCT03407430
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Generalized Tonic Clonic Seizures
A Safety, Efficacy and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric and Adult Subjects With Primary Generalized Tonic-Clonic (i.e., Grand Mal) Seizures.
The study is designed to evaluate the safety, tolerability and efficacy of two doses of pregabalin as add-on treatment in pediatric and adult subjects with Primary Generalized Tonic-Clonic (PGTC) seizures as compared to placebo.
- Trial name
- NCT01747915
- Testing
- Pregabalin Dose Level 1, Pregabalin Dose Level 2
- Where
- 127 sites in United States, Austria and 24 more
- Volunteers
- 219 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Compliance, Chronic Pain
Evaluation of a Compliance Marker in Prescription Opioid Abusers With Chronic Pain
In a small, well-characterized sample of prescription opioid abusers (POAs) with chronic pain and on buprenorphine therapy, this study will investigate the utility and feasibility of two novel tracer compounds, and in combination…
- Trial name
- NCT02276989
- Testing
- acetazolamide, Quinine, Riboflavin
- Where
- United States
- Sponsor
- Georgetown University
Epilepsy, Partial
To Evaluate the Long-Term Safety of Pregabalin in Refractory Partial Epilepsy.
To evaluate the long-term safety of pregabalin in refractory partial epilepsy.
- Trial name
- NCT00141414
- Testing
- Pregabalin
- Where
- 25 sites in United States, Germany
- Volunteers
- 82 people
- Sponsor
- Pfizer
Herpes Zoster, Postherpetic Neuralgia
Study to Find Out if Therapy With the Drug Pregabalin Relieves Pain During Shingles Compared With Placebo
The purpose of this study is to see if therapy with the drug pregabalin relieves pain during shingles compared with placebo. A placebo is an inactive substance.
- Trial name
- NCT00352651
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Postoperative Pain
Pre- Versus Post-incisional Pregabalin for Postoperative Pain Attenuation and Analgesics Spare in Orthopedic Oncologic Patients
Hypothesis No studies considered the comparison of preemptive vs. post-surgery Pregabalin (PGL) only administration. The investigators believe that the administration of PGL preemptively would diminish pain sensation and…
- Trial name
- NCT01359059
- Testing
- Pregabalin
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Epilepsy, Partial Seizure Disorder
Comparative Study Of Pregabalin And Gabapentin As Adjunctive Therapy In Subjects With Partial Seizures
To compare the efficacy of pregabalin and gabapentin, as adjunctive therapy in subjects with partial seizures.
- Conditions
- Epilepsy, Partial Seizure Disorder, Epilepsies, Partial, Complex Partial Seizure Disorder
- Trial name
- NCT00537940
- Testing
- Pregabalin, Gabapentin
- Where
- 8 sites in Costa Rica, El Salvador and 2 more
- Volunteers
- 482 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Alcoholism
Pregabalin for Alcohol Dependence
The study hypothesis is: Pregabalin is superior to placebo in preventing relapse to drinking and reducing drinking severity
- Trial name
- NCT02205879
- Testing
- Pregabalin
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- St. Petersburg Bekhterev Research Psychoneurological Institute