Clinical trials: Pregnancies
Renal Replacement Therapy, Mortality
Referral Patterns for Hospital Acquired Acute Kidney Injury and Relevance to Renal Outcomes
Few studies analyzed the referral time to nephrologists and its impact on the patient outcome in a large cohort. The investigators described the incidence and determined the outcome with respect to renal function recovery, renal…
- Trial name
- HA-AKI (NCT01151514)
- Testing
- Nephrologist referral
- Where
- Switzerland
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Pulmonary Hypertension, Pregnancy, High Risk
Pregnant Women With Pulmonary Hypertension in China
Little is known about the status of maternal, obstetric and neonatal complications and the potential predictors of developing heart failure (HF) in the mothers with pulmonary hypertension in China.
- Trial name
- NCT05198206
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
End-stage Renal Disease
Two phosphAte taRGets in End-stage Renal Disease Trial (TARGET)
Patients with end-stage renal disease (ESRD) who have elevated serum phosphate (P) levels have significantly higher mortality rates compared to those with normal P.
- Trial name
- TARGET (NCT01994733)
- Testing
- Calcium carbonate ( Intensive phosphate control), Calcium carbonate (Liberalized phosphate control)
- Where
- 5 sites in Canada
- Volunteers
- 104 people
- Sponsor
- Unity Health Toronto
Diabetic Nephropathies
Add-on Pentoxifylline to Losartan Versus Increasing Dose of Losartan on NT-PRO BNP in Type 2 Diabetics With Nephropathy
This study was designed to assess the efficacy of adding pentoxifylline to losartan in comparison with increasing dose of losartan in type 2 diabetes patients with nephropathy.
- Trial name
- NCT03006952
- Testing
- Pentoxifylline, Losartan
- Where
- Iran
- Volunteers
- 59 people
- Sponsor
- Tehran University of Medical Sciences
Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta
MoDi Twin Placental Imaging
Twin-twin transfusion syndrome (TTTS) can arise in monochorionic, diamniotic (MoDi), those identical twins arising from division of a single fertilized ovum at 4-8 days gestational age (GA) or monochorionic, monoamniotic (MoMo or…
- Conditions
- Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta, Monochorionic Twins, Ultrasound Doppler
- Trial name
- NCT07667647
- Testing
- Verasonics Vantage 256 Ultrasound
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Carilion Clinic
Premature Birth of Newborn
Supporting and Enhancing NICU Sensory Experiences (SENSE)
Seventy preterm infants born less than or equal to 32 weeks gestation were put into either the sensory-based intervention (experiment) group or traditional care (control) group. Consecutive admissions at St.
- Trial name
- SENSE (NCT03316547)
- Testing
- SENSE Program
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Pregnancy Complications Affecting Fetus (Diagnosis)
Maternal Serum Pentraxin 3 in Early Pregnancy to Predict Gestational Diabetes Mellitus
To investigate the association of maternal serum concentrations of pentraxin 3 in early pregnancy with gestational diabetes mellitus and to explore its potential value in the prediction of GDM.
- Trial name
- NCT03563638
- Testing
- 75gOGTT
- Volunteers
- 824 people, healthy volunteers welcome
- Sponsor
- Shanghai First Maternity and Infant Hospital
Pregnancy, Embryo Implantation
Administration of GnRH Antagonist to Oocyte Donation Recipients
This prospective and randomized study was performed to evaluate whether the replacement of GnRH agonist by a GnRH antagonist in oocyte donation recipients during endometrial preparation has any impact on pregnancy and…
- Trial name
- GnRH-Ovodon (NCT00635258)
- Testing
- triptorelin (Decapeptyl®, Ipsen Pharma, Barcelona, Spain), GnRH antagonist (Orgalutran®)
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centro Ginecologia y Obstetricia.
Tubal-preserving Treatment of Tubal Ectopic Pregnancy, Tubal Pregnancy
The Selection of Pregnancy for Patients After Tubal Ectopic Pregnancy Treatment
The incidence of re-ectopic pregnancy in patients with tubal ectopic pregnancy increases significantly, which may be related to the condition of the fallopian tubes, such as tubal inflammation, tubal obstruction and other…
- Conditions
- Tubal-preserving Treatment of Tubal Ectopic Pregnancy, Tubal Pregnancy, Pregnancy Preparation
- Trial name
- TSOPFPATEPT (NCT05498558)
- Testing
- No intervention.
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Infant Colic, Postpartum Depression
Measuring and Reducing Excessive Infant Crying
Excessive infant crying (EIC) is likely to increase the risk of child abuse. The investigators propose a randomized trial using an intervention based on recommendations of Karp.
- Trial name
- UTHealth THB (NCT01217658)
- Testing
- The Happiest Baby on The Block, AAP Infant Colic counseling
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The University of Texas Health Science Center, Houston
Gestational Trophoblastic Neoplasia
Dostarlimab in Chemoresistant Gestational Trophoblastic Neoplasia
The purpose of this study is to see if Dostarlimab is an effective treatment for Gestational Trophoblastic Neoplasia (GTN).
- Trial name
- NCT05405192
- Testing
- Dostarlimab
- Where
- United States
- Sponsor
- University of Miami
Cardiac Surgery
Risk of Oxygen During Cardiac Surgery Trial
The investigators will recruit and randomize 200 elective cardiac surgery patients to receive physiologic oxygenation (normoxia) or hyper-oxygenation (hyperoxia) during surgery to test the hypothesis that intraoperative…
- Trial name
- ROCS (NCT02361944)
- Testing
- Oxygen - normoxia, Oxygen - hyperoxia
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Vanderbilt University
Preeclampsia, Pregnancy
Different Regulation of Immune Cells in Patients With Preeclampsia
Adaptation of the maternal immune system to accommodate the semi-allogeneic fetus is necessary for pregnancy success. Dysregulation of this immune adaptation is implicated in reproductive disorders as infertility, recurrent…
- Trial name
- NCT02691364
- Testing
- Blood withdrawal
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Infertility, Female, Pelvic Organ Prolapse
Apical Pelvic Support in Infertility Patients
This study aims to evaluate apical pelvic compartment support in infertility patients at the time of hysteroscopy. Apical pelvic compartment evaluation for pelvic organ prolapse will be performed in infertility patients…
- Conditions
- Infertility, Female, Pelvic Organ Prolapse, Pelvic Floor Disorders
- Trial name
- NCT04039009
- Testing
- Pelvic Organ Prolapse Quantification system
- Where
- Turkey (Türkiye)
- Volunteers
- 1,100 people
- Sponsor
- Uludag University
Focal Segmental Glomerulosclerosis
LDL-Apheresis for FSGS CardioRenal Outcomes
Focal segmental glomerulosclerosis (FSGS) is the most common cause of end-stage renal disease (ESRD) in adolescents. The refractory nature of FSGS and a more than 30% recurrence rate after kidney transplantation renders treatment…
- Trial name
- NCT04088799
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Kidney Diseases, Hemodialysis
Effects of Supplementation With Tocotrienol on Chronic Kidney Disease Patients
The objective of this study is to evaluate the supplementation with tocotrienol, a vitamin E compound on inflammation, oxidative stress, and microbiota on Chronic Kidney Disease patients.
- Conditions
- Chronic Kidney Diseases, Hemodialysis, Microbiota, Oxidative Stress
- Trial name
- NCT04900532
- Testing
- Tocotrienol rich fraction
- Where
- Brazil
- Volunteers
- 61 people
- Sponsor
- Universidade Federal Fluminense
Acute Renal Failure
Development and Validation of an Enhanced Prediction Score for Postoperative Acute Renal Failure After Liver Resection
Post-operative acute renal failure is a severe post-operative complication and is associated with high mortality. The enhanced prediction score, including pre-as well as intra-operative predictors accurately predicted ARF…
- Trial name
- NCT01318798
- Where
- Switzerland
- Volunteers
- 549 people
- Sponsor
- University of Zurich
Schistosomiasis
S. Japonicum and Pregnancy Outcomes
The purpose of the study is to understand whether the drug praziquantel (PZQ) is safe for the mother and developing baby when the mother has schistosomiasis (a type of worm) infection, and whether the drug may improve the…
- Trial name
- NCT00486863
- Testing
- Praziquantel
- Where
- Philippines
- Volunteers
- 370 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Coronary Calcification
Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients
Until 2013 the reported incidence of chronic kidney disease varied widely between countries, reporting the highest prevalence Taiwan, the region of Jalisco in Mexico and United States, with 458, 421 and 363 individuals per…
- Trial name
- NCT04247087
- Testing
- phytomenadione
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Mexicano del Seguro Social
Chronic Kidney Diseases, Hemodialysis Complication
Exposure Of Bisphenol Analogues In Chronic Kidney Disease and Dialysis Patients
In this retrospective study, the serum levels of Bisphenol A (BPA) and three BPA analogs, namely, bisphenol B (BPB), bisphenol S (BPS), and bisphenol F (BPF), in patients with CKD, patients on dialysis therapy and healthy control…
- Trial name
- NCT04100421
- Where
- China
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University