Clinical trials: Pregnancy
Pregnancy, Postpartum Period
Impact of Collaborative Care for Pregnant Women With Opioid Use Disorder in Low-Resource Obstetric Settings
The investigators seek to adapt a collaborative care model (CCM) for community-based, low-resource obstetric settings and to test the effects of this adapted CCM on health outcomes among Pregnant, postpartum, and parenting person…
- Conditions
- Pregnancy, Postpartum Period, Opioid Use Disorder
- Trial name
- NEST (NCT06956352)
- Testing
- Usual Care, Adapted Collaborative Care Model (CCM)
- Where
- United States
- Volunteers
- 1,350 people
- Sponsor
- University of Pittsburgh
Pain, Analgesia
Impact of the NeuroCuple Device on Pain Management After Cesarean Delivery
This will be a single-center, sham-controlled, 3 arms, randomized (1:1:1) prospective study in females undergoing cesarean delivery to investigate the impact of NeuroCuple™ non-pharmacological analgesic device for management of…
- Conditions
- Pain, Analgesia, Pregnancy
- Trial name
- NCT07185425
- Testing
- NeuroCuple
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Inova Health Care Services
Hypertension
Cardiac Effects of Mineralocorticoid Receptor Antagonism After Hypertensive Disorders of Pregnancy
The goal of this clinical trial is to determine if the medication eplerenone yields greater improvements in coronary microvascular function than chlorthalidone in women who experienced hypertension during pregnancy and…
- Trial name
- CARDAMOM (NCT07238400)
- Testing
- Eplerenone 100 mg daily, Chlorthalidone 25 mg daily, Potassium Chloride
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Massachusetts General Hospital
Virtual Reality, Postpartum Depression (PPD)
Virtual Reality-Assisted Intraoperative Sensory Modulation on Postpartum Depression and the Kynurenine Pathway
The research will be conducted as a prospective, observational, and comparative study with 98 pregnant volunteers aged 18-45 at Düzce University Faculty of Medicine.
- Conditions
- Virtual Reality, Postpartum Depression (PPD), Kynurenine Pathway and Its Metabolites, Pregnancy
- Trial name
- VR effect (NCT07300176)
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Duzce University
Fear of Childbirth, Pregnancy
Mindfulness Psychoeducation Based on Transtheoretical Model for Fear of Childbirth
Childbirth is a significant life event with important physical and psychological effects on pregnant women. Due to uncertainty during pregnancy, many women experience fear of childbirth.
- Trial name
- NCT07624253
- Testing
- Mindfulness-Based Psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Nigde Omer Halisdemir University
Pregnancy Complications
Effect of Direct Myofascial Release Technique Combined With Exercise on Round Ligament Pain During Pregnancy
Study's objective is to explore effect of combining direct myofascial release technique with therapeutic exercises on decreasing round ligament pain during pregnancy.The main question to be answered by this study: Does a…
- Trial name
- NCT07715422
- Testing
- Manual therapy technique named myofascial release combined with therapeutic exercises
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Beni-Suef University
Hyperemesis Gravidarum, Nausea and Vomiting of Pregnancy
Diagnostic and Psychometric Validation of the FRENCH HELP Scale in Hyperemesis Gravidarum
Severe forms of nausea and vomiting of pregnancy (NVP) are classified as hyperemesis gravidarum (HG). NVP is debilitating in approximately 35% of women impairing daily life and professional activities while negatively affecting…
- Trial name
- French-HELP (NCT07767071)
- Testing
- HELP score
- Where
- 7 sites in France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Bariatric Surgery, Pregnency
Mother and Offspring's Nutritional Status -Pregnancy After Maternal Bariatric Surgery
The goal of this observational study is to learn how bariatric surgery affects the health and nutritional status of women and their babies during pregnancy and after birth.
- Conditions
- Bariatric Surgery, Pregnency, Reproductive Health and Childbirth, Pregnancy and Delivery
- Trial name
- MOBS (NCT07877233)
- Testing
- Post-Bariatric Maternal and Infant Health Study, Observation arm
- Where
- 3 sites in Norway
- Volunteers
- 210 people
- Sponsor
- Helse Nord-Trøndelag HF
Pregnancy Disease, Malignancy
Maternal and Fetal Outcomes in Pregnancy With Malignancy
This retrospective study aims to evaluate maternal and fetal outcomes in women diagnosed with malignancy during pregnancy at Assiut University Women's Health Hospital.
- Trial name
- NCT07882329
- Volunteers
- 50 people
- Sponsor
- Assiut University
Pregnancy Complicated With Intrauterine Adhesion
Comparison of Operative Hysteroscopy and Vacuum Aspiration for Terminating First-trimester Pregnancy With Intrauterine Adhesions
In cases of early pregnancy complicated with intrauterine adhesions (IUAs), termination of pregnancy is prone to incomplete abortion with retained gestational products, failed abortion or uterine perforation due to altered…
- Trial name
- NCT07883057
- Testing
- Vacuum Aspiration Group, Hysteroscopy adhesiolysis combined with vacuum aspiration
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Pregnancy, Prenatal Care
Comparing AI and Standard Pregnancy Chatbots
Many pregnant women in India use mobile phones to get health information. Nivi runs a free WhatsApp service called askNivi that answers questions about pregnancy and sends reminders about prenatal care visits.
- Conditions
- Pregnancy, Prenatal Care, Maternal Health
- Trial name
- NCT07883993
- Testing
- Scripted maternal health chatbot, MATRI retrieval-augmented maternal health chatbot
- Where
- India
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Nivi, Inc.
Iron Deficiency Anemia in Pregnancy, Iron Deficiency in Pregnancy
Safety and Efficacy of Iron Prophylaxis With on Iron Homeostasis in Healthy Pregnant Women
The clinical study aims to evaluate the effect of iron supplementation in preventing the onset of Iron Deficiency Anemia during pregnancy.
- Trial name
- NCT07884617
- Testing
- Iron plus folic acid, Folic acid
- Where
- Italy
- Volunteers
- 162 people
- Sponsor
- IBSA Farmaceutici Italia Srl
Hepatitis C, Chronic, Pregnancy; Infection
Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy
This is a multicenter, single arm study of Sofosbuvir/Velpatasvir (SOF/VEL) for treatment of chronic hepatitis C infection during pregnancy.
- Trial name
- STORC (NCT05140941)
- Testing
- Sofosbuvir/Velpatasvir 400 MG-100 MG Oral Tablet
- Where
- 9 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Catherine Anne Chappell
Diabetes, Gestational, Pregnancy Complications
Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes
Pregnant women aged 18-45 with gestational diabetes (GDM) will take part in this study. We want to see how two different insulin treatments affect their blood sugar after they eat.
- Conditions
- Diabetes, Gestational, Pregnancy Complications, Glucose Metabolism Disorders, Glucose Intolerance During Pregnancy
- Trial name
- INHALE-GDM (NCT06535789)
- Testing
- Inhaled Technosphere Insulin
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Jaeb Center for Health Research
Sickle Cell Disease, Pregnancy Related
Prophylactic Transfusion In Pregnant in Women With Sickle Cell Disease
The goal of this study is to determine if there is a positive effect of prophylactic red blood cell (RBC) transfusion of leukoreduced, ABO, Rh (D/Cc/Ee) and Kell matched blood compared to standard of care on the number of…
- Trial name
- ProTIP (NCT06979492)
- Testing
- Prophylactic Transfusion Intervention group: Transfusion, Control group
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Contraception, Birth Control
Safety of a Contraceptive Copper Vaginal Ring
Many birth control options today come with unwanted side effects or risks. Hormonal methods can affect both mental and physical health, while devices like copper IUDs carry risks such as uterine perforation or infection.
- Conditions
- Contraception, Birth Control, Pregnancy Prevention
- Trial name
- NCT07666997
- Testing
- Vaginal Ring
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Elle, MD Biotechnologies Inc.
Pregnancy, Birth
Effects of Online and App-Based Prenatal Yoga on Birth Outcomes
This randomized controlled trial evaluated the effects of a midwife-led digital prenatal yoga intervention via the MIDWIFEYOGA mobile application on birth and neonatal outcomes among 74 primiparous women.
- Conditions
- Pregnancy, Birth, Yoga
- Trial name
- NCT07880093
- Testing
- Online and App-Based Prenatal Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Vasviye Eroğlu
Sleep, Circadian Rhythm
HEARTBEAT SOUND FOR BREASTFEEDİNG DİFFİCULTİES: A RANDOMİZED CONTROLLED TRİAL
This randomized controlled trial aims to evaluate the effect of listening to a pre-recorded, standardized maternal heartbeat sound on perceived stress levels and breastfeeding self-efficacy in mothers experiencing early…
- Conditions
- Sleep, Circadian Rhythm, Pregnancy, Newborn
- Trial name
- NCT07881484
- Testing
- Standardized Maternal Heartbeat Sound Application
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hakan Avan
Pregnancy Related, Perinatal Depression
Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care
This study will provide high-quality, representative data on the capacity of Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care (EleVATE GC) to reduce perinatal depression, preterm birth, and…
- Trial name
- EleVATE GC (NCT04838210)
- Testing
- EleVATE Group Care, Individual Prenatal Care
- Where
- 4 sites in United States
- Volunteers
- 416 people
- Sponsor
- Washington University School of Medicine
Gestational Diabetes, Pregnancy, High Risk
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
- Conditions
- Gestational Diabetes, Pregnancy, High Risk, Overweight and Obesity
- Trial name
- iGDM (NCT05124808)
- Testing
- Intensive glycemic targets, Standard glycemic targets
- Where
- 5 sites in United States
- Volunteers
- 828 people
- Sponsor
- Indiana University